A new generation of technology. For a new generation of patients. Elite MPX. Powered by MultiPlex

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1 A new generation of technology. For a new generation of patients Elite MPX Powered by MultiPlex

2 A laser that adjusts to your patients. How fitting. Today, your patients are both young and old. They are light skinned, dark skinned and somewhere in between. No matter what age, race or ethnicity, they have high treatment expectations but little time. It s a new generation of patients, and the new Elite MPX is the first aesthetic workstation designed to treat them. Now you can deliver customized hair, vascular and anti-aging treatments to a wider range of patients more quickly and effectively than ever before. Welcome to Generation MPX. They want it all. Now you can be the one to give it to them.

3 1 Before After 2 Before After 3 Elite MPX. The difference is clear. Before After 4 Whether you re an experienced practitioner taking the next step or introducing aesthetic medicine into your practice, Elite MPX can give you dramatic results. No wonder it s the solution for a new generation. Before After

4 The Elite MPX removes all obstacles. Before, your patients had to fit your laser. But with more technologies and applications in a single workstation, you can treat all blends of skin types more effectively than ever. In this changing world of ours, that s a critical advantage. Only Elite MPX has our patented MultiPlex TM sequencing technology two wavelengths blended for the best possible results. Remove hair, veins, pigmented lesions and all that stands between you and a greater ROI. The changing face of our world 1 Non-Hispanic white people will decrease 46% by 2050 Hispanic, black, Asian and Native American people will increase 56% by 2050 Human migration is increasing globally According to census projections, by 2050 one in every two Americans will be of Hispanic, Asian, African, or Indian descent Today, over 40% of the global population is non-caucasian

5 Putting incredible new power in your hands. With our proven, patented MultiPlex technology, Elite MPX gives you more applications, drives more consumer demand and helps you generate more revenue. Other advantages include: Optimal treatment of facial and leg veins The flexibility to treat pigmented lesions such as age spots, freckles and photo-aged skin The most comprehensive range of hair removal applications today MPX dual-wavelength technology. Only from Cynosure. The time is right for MultiPlex two wavelengths that fire sequentially and work beautifully together. The Elite MPX provides safer, more effective treatments than single-wavelength systems, for a broader range of skin types and conditions. Target vein Initial 755 nm Alexandrite exposure to vein Followed by Low dose 1064 nm Nd:YAG automatically delivered vessel elimination MultiPlex for vascular or

6 Today, you need greater customization. Elite MPX delivers. Eight different spot sizes with adjustable pulse durations, combined with two sequentially firing wavelengths, allows you to provide customized laser prescriptions for today s complex mix of skin types. Vascular Treatment The 755 nm wavelength converts oxy-hemoglobin to methemoglobin. This increases absorption of the deeper penetrating 1064 nm energy by % in the targeted vessel. Multiplex allows the 1064 nm energy to be reduced due to high absorption by methemoglobin greater absorption + deeper penetration = optimized results Target Hair Follicle (darker skin type) Hair Removal By blending these interchangeable wavelengths for darker skin and finer hair, the patient will benefit from the added melanin absorption of the 755 nm wavelength. That means greater Tx efficacy with less pain 2. Less fluence is required for each respective wavelength 755 nm component has increased hair follicle energy absorption reduced 1064 nm component decreases pain nm ideal for lighter skin types 1064 nm ideal for darker skin types INITIAL 1064 nm Nd:YAG EXPOSURE TO FOLLICLE FOLLOWED BY LOW DOSE 755 nm Alexandrite AUTOMATICALLY DELIVERED Skin Rejuvenation By preheating with the deeper penetrating 1064 nm wavelength, then following with the 755 nm wavelength, skin treatment is uniquely combined. Targets pervasive dyschromia 1064 nm wavelength targets collagen and photodamaged skin 755 nm wavelength targets unwanted pigment Less fluence required for each respective wavelength Hair Follicle elimination hair removal treatment

7 The perfect balance of power, ease and control. New features create the ultimate experience for both clinician and patient. Xenon Pulsed Light (XPL2) Cynosure s new XPL2 has been designed to meet today s most demanding aesthetic goals. Higher power Interchangeable filters Integrated skin cooling Faster treatments Applications Sun-damaged skin Dyschromia Pigmented lesions Diffuse redness, rosacea Graphical User Interface (GUI) Elite MPX s completely redesigned user interface makes operation simple & easy Touch-screen air cooling controls Easy software upgrades Integrated Zimmer Cooling Conventional Zimmer Cooling Integrated Zimmer Cooler We ve taken Zimmer s SmartCool proven air cooling technology and built it right in, saving space, increasing efficiency and making treatments easier than ever Skin temperature post 5 sec. Thermal camera imaging shows faster skin cooling of integrated Zimmer cooling vs conventional Zimmer cooling. 18 mm 15 mm This skin cooling system is exclusive to Cynosure. It combines the best features of Zimmer technology into one compact module, making it best in class for cooling Just one service contract 18 mm Spot Size The new 18 mm spot size gives you: More power in your hands 44% more treatment area per pulse* Less treatment time = More patient throughput = More revenue in your pocket 44% More treatment Area per pulse with More Power *As compared to standard 15 mm spot sizes

8 Aesthetic Workstation System Type Alexandrite Nd:YAG MultiPlex Wavelength 755 nm 1064 nm 755 nm nm Pulse Width msec msec msec Maximum Fluence per Spot Size * 18 mm 22 J/cm 2 27 J/cm 2-15 mm 30 J/cm 2 40 J/cm 2 32 J/cm 2 12 mm 40 J/cm 2 60 J/cm 2 50 J/cm 2 10 mm 50 J/cm 2 90 J/cm 2 70 J/cm 2 7 mm J/cm J/cm 2 5 mm 25 J/cm J/cm J/cm 2 3 mm J/cm mm** J/cm 2 - Maximum Rep Rate 10 Hz 10 Hz 1.5 Hz Aiming Beam Skin Cooling System Electrical Requirements Size (H x W x D) Weight *Independent of pulse width **Optional hand piece Adjustable continuous pulse or single pulse operation Red Cold Air ( l/min) 230 VAC/30A (117 cm 59 cm 83 cm) 298 lbs (135 kg) Sources: 1 US Census Bureau 2 Lasers in Surgery and Medicine Supplement, 2008; Abstract #118, Hair Removal with Blended 755/1064 nm Laser Energy, E. Victor Ross et. al. ASLMS 2008 presentation. Before and After Photos: 1 Courtesy of A Ribé, MD 2-3 Courtesy of C. Arroyo, MD 4 Courtesy of A. Badawi, MD CORPORATE HEADQUARTERS United States Cynosure, Inc. 5 Carlisle Road Westford, MA USA Tel: Toll-Free: Cynosure and the Cynosure logo are proprietary trademarks of Cynosure, Inc Cynosure, Inc Rev. 2

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