SYN -EYE. Lineless eyes within 7 days

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Magnus Wilkinson
5 years ago
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1 SYN -EYE Lineless eyes within 7 days

SYN -EYE: 4-in-1 blend composition Dunaliella salina extract Palm-Lys-Val-Lys-OH Dunaliella salina is a very small unicellular microalgae, discovered in 1838 by Dunal in the salters of Montpellier.

This feature, based on a powerful cocktail of different of secondary metabolites such as amino acids and carbohydrates, qualifies D. Salina as a unique ingredient to reload the skin with new energy.

mechanism to produce collagen via TGF-β. Collagen represents the main component of the ECM (Extracellular Matrix) of the dermal connective tissue.

When applied to the skin D-Panthenol readily converts to pantothenic acid. Pantothenic acid, also known as vitamin B5, is part of the B group vitamins and is classified as a water-soluble vitamin.

2 SYN -EYE: 4-in-1 blend composition Dunaliella salina extract Palm-Lys-Val-Lys-OH Dunaliella salina is a very small unicellular microalgae, discovered in 1838 by Dunal in the salters of Montpellier. It grows in salt water with up to 3% salinity which is nine times higher than sea water. Living in such harsh conditions, D. salina has become an expert of surviving. This feature, based on a powerful cocktail of different of secondary metabolites such as amino acids and carbohydrates, qualifies D. Salina as a unique ingredient to reload the skin with new energy. Energizes and protects in vitro mitochondria Stimulates in vitro epidermal renewal Palm-Lys-Val-Lys-OH is a small synthetic tripeptide with a unique sequence that imitates the human body s own mechanism to produce collagen via TGF-β. Collagen represents the main component of the ECM (Extracellular Matrix) of the dermal connective tissue. Panthenol Pro Vitamin B5 or D-Panthenol has been used for years in hair care products. It functions as a Humectant, increasing the water content in hair and improves its elasticity. When applied to the skin D-Panthenol readily converts to pantothenic acid. Pantothenic acid, also known as vitamin B5, is part of the B group vitamins and is classified as a water-soluble vitamin. Pantothenic acid is then incorporated as an important component in the energy cycle of the cell. Panthenol itself can also attract water into the upper layer of the skin and can enhance the regeneration of skin. HO Helps to keep the skin moist and supple Inhibits irritation and reddening H Protects from collagen network degradation Boosts collagen production OH NH OH Hyaluronic acid Hyaluronic acid (HA) is a non-branched, naturally occuring polysaccharide of the human body. It is mainly found in the extracellular matrix. HA today is mainly produced by fermentation, followed by an extended purification. During the process special attention is paid to maintain a particular molecular size range (35 to 55) KD to ensure the best combination between film forming properties and anti-aging benefits. Excellent moisturizing benefit Anti-wrinkle and firming effect DSM internal studies

3 The windows to the world reduction of puffiness What consumers are seeking. It s been said the eye is the window to the outside world. This is why it attracts a lot of attention and it requires a lot of care. With long standing experience in skin care, DSM has created a multifunctional, patented ingredient complex that fulfill consumers expectation for high- and fast-performing eye care products. reduction of wrinkles and fine lines reduction of dark circles less tired more energetic Key facts Unique product features SYN -EYE combines SYN -Peptide know-how with superior bioactives in a multifunctional eye care formula It offers multi-target science based approach to fight against the most common concern in eye care the appearance of lines & wrinkles and dark circles It shows significant effects in only 7 days SYN -EYE is a patented complex and fully China compliant Benefits Reduces visibly the appearance of lines and wrinkles around the eye within 7 days Reduces the appearance of dark circles Improves the skin s texture and smooths the delicate skin eye area Moisturizes, protects, and energizes the skin around the eyes Cosmetic applications Fast-acting and multi-functional eye care formulas Anti-aging eye care products to minimize the visual aspect of lines and wrinkles Product that focuses on youthful, fresh, and smooth facial skin Product that reduces the appearance of dark circles Suggested concentration 1% SYN -EYE INCI name (active) Palmitoyl Tripeptide-5, Panthenol, Sodium Hyaluronate, Algae (Dunaliella Salina) extract overall anti-aging effect fast results Need for multifunctional products The eye area ages faster as it is the thinnest and most fragile area of skin. Over the years the production of collagen slows down and an extensive muscle contraction contributes to the formation of lines and wrinkles. The delicate area around the eyes needs special care and focus on different parameters, such as collagen reduction, microcirculation and skin thinning, all of which needs to be taken care of. Most of the products in the market only treat one aspect and disregard others. However, the multifunctionality of SYN -EYE offers more opportunity to treat this sensitive area in an effective and gentle way. This multifunctionality is highly accredited in consumer feedback. Mintel Color Cosmetics, US, July 213. Datamonitor 213 illuminating 71% said multifunctional products are convenient and time saving. 48% of global skin care shoppers found it important or very important to minimize the number of products used in their health and beauty regime. 68% said multifunctional products save me money instead of buying multiple products. 66% said multifunctional products allow me to reduce or replace the number of skincare products I use.

SYN -EYE 4 in 1 blend in vivo efficacy Effect on wrinkles and fine lines High consumer

in a 4 week, split-face study amongst European female volunteers in the age range of

Visible difference in skin color in the dark circle area Result: SYN -EYE shows a

It compared 2 samples (SYN -EYE and a competitive benchmark) against a placebo in an eye

Measurement of different parameters on wrinkle and dark circles has been conducted by

4 SYN -EYE 4 in 1 blend in vivo efficacy Effect on wrinkles and fine lines High consumer acceptance Effect on dark circles Significant in 7 days SYN -EYE efficacy was evaluated in a 4 week, split-face study amongst European female volunteers in the age range of Visible difference in skin color in the dark circle area Result: SYN -EYE shows a visibly brighter skin color in dark circle area after only 14 days. It compared 2 samples (SYN -EYE and a competitive benchmark) against a placebo in an eye care cream. Measurement of different parameters on wrinkle and dark circles has been conducted by Primos or DermaTop; image analysis has been performed by Newtone. Dark Circle reduction (ITA in ) +1 Day Day 7 Day 14 Day % SYN -EYE 1 % Benchmark -5 p<.5. vs. day. ITA 3 is visable bright ΔITA = 3 dark INCI: Glycerin, Albizia Julibrissin Bark Extract, Darutoside

Continuous visible improvement on fine lines and wrinkles Day After 7 days with 1% SYN -EYE After 14 days with 1% SYN -EYE After 28 days with 1% SYN -EYE Significant reduction in the appearance of

SYN -EYE 1 % Benchmark Placebo Reduction in skin roughness (ΔRa in µm) +1-1 -2-3 -4-5 Day 7 Day 14 Day 28 1 % SYN -EYE 1 % Benchmark Placebo vs. day & placebo. vs. day, benchmark & placebo. p<.

Result: SYN -EYE shows a significant effect on skin smoothing in only 7 days. Let s ask the consumer!

5 Continuous visible improvement on fine lines and wrinkles Day After 7 days with 1% SYN -EYE After 14 days with 1% SYN -EYE After 28 days with 1% SYN -EYE Significant reduction in the appearance of wrinkles compared to benchmark and placebo Smoothing noticeable reduction in roughness compared to day Subject #46 Wrinkle reduction (DRz in µm) Day 7 Day 14 Day 28 +9% 1 % SYN -EYE 1 % Benchmark Placebo Reduction in skin roughness (ΔRa in µm) Day 7 Day 14 Day 28 1 % SYN -EYE 1 % Benchmark Placebo vs. day & placebo. vs. day, benchmark & placebo. p<.5 vs. day & placebo. vs. day, benchmark & placebo. p<.5 Result: SYN -EYE shows a significant anti-wrinkle efficacy in 7 days. Result: SYN -EYE shows a significant effect on skin smoothing in only 7 days. Let s ask the consumer! Consumer questionnaire: products efficacy on wrinkles Consumers confirmed outstanding activity of SYN -EYE Satisfied subjects (%) % 66 % under-eye wrinkles 75 % 69 % crow s feet 1 % SYN -EYE 1 % Benchmark 7 % 63 % lines around the eyes 72 % 52 % puffiness 7 % 58 % dark circles Result: Higher consumer acceptance in all key aspects compared to benchmark.

6 Europe DSM Nutritional Products Europe Ltd. P.O. Box 2676, 42 Basel Switzerland Phone: Fax: Asia Pacific DSM Singapore Industrial Pte Ltd. trading as DSM Nutritional Products Asia Pacific 3 Pasir Panjang Road Mapletree Business City #13-31 Singapore Phone: Fax: info.pc-apac@dsm.com North America DSM Nutritional Products, LLC 45 Waterview Boulevard, Parsippany, NJ 754 United States of America Phone: Fax: info.pc-na@dsm.com Latin America DSM Produtos Nutricionais Brasil S.A. Avenida Engenheiro Billings, 1729 Prédio 31 Sala A - CEP:5321-1, São Paulo SP Brasil Phone: Fax: info.pc-latam@dsm.com 215 DSM Nutritional Products, 42 Basel, Switzerland. All rights reserved. No part of this brochure may be reproduced, distributed or translated in any form or by any means, or stored in a database or retrieval system, without the prior written permission of DSM Nutritional Products AG ( DSM ). While making reasonable efforts to ensure that all information in this brochure is accurate and up to date, DSM makes no representation or warranty of the accuracy, reliability, or completeness of the information. Use of this information shall be at your discretion and risk. Nothing herein relieves you from carrying out your own suitability determinations and tests and from your obligation to comply with all applicable laws and regulations and to observe all third party rights. The uses and claims for DSM s products recommended in the brochure should be adapted to the current local regulatory environment. We disclaim any and all liability in connection with your product or its use. P75

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