MATERIAL SAFETY DATA SHEET

Transcription

1 MATERIAL SAFETY DATA SHEET 1 PRODUCT AND COMPANY IDENTIFICATION Product Name: POROS HE kg Product No./Trade Name(s): D50: ; ; ; ; ; ; ; POROS D50 MICRON CHROMATOGRAPHY MEDIA; POROS D 50 MICRON CHROMATOGRAPHY MEDIA; POROS 50D 25 ml BULK PK; POROS 50D HE50: ; ; ; ; ; ; ; ; POROS HE50, 10 ml; POROS HE50, 25 ml; POROS HE50, 125 ml; POROS HE50, 1 L; POROS HE50, 5 L; POROS HE50, 10 L; POROS HE50, 1.5 kg; POROS 50 MICRON HEPARIN 50 ml HQ150: ; ; ; ; ; ; ; ; ; ; ; POROS 50 HQ 25 ml BULK PK; POROS 50 HQ 125 ml BULK PK; POROS 50HQ1 1,000 ml BULK; POROS 50HQ1 10,000 ml BULK; POROS HQ kg; POROS 50 MICRON HQ1 STRONG ANION EXCHANGE; POROS HQ 50 MICRON CHROMATOGRAPHY MEDIA HS250: ; ; ; ; ; ; ; ; POROS 50 HS 5 ml BULK PK; POROS 50 HS 25 ml BULK PK; POROS 50 HS 125 ml BULK PK; POROS HS 50 MICRON CHROMATOGRAPHY MEDIA MC50: ; ; ; ; ; ; FG, POROS 50 MC 25 ml BULK PACK; FG, POROS 50 MC 50 ml BULK PK; FG, POROS 50 MC 250 ml BULK PK; FG, POROS 50 MC 1000 ml BULK PK; FG, POROS 50 MC 5000 ml BULK PK; FG, POROS 50 MC 10,000 ml BULK PK OH150: ; ; POROS OH150 4 kg, EtOH; POROS 50 OH1 OH250: ; POROS OH250, EtOH PI150: ; ; ; ; ; ; ; ; POROS 50 PI 25 ml BULK PK; POROS 50 PI 125 ml BULK PK; POROS 50PI COATING (2000 g); POROS PI 50 MICRON CHROMATOGRAPHY MEDIA; POROS PI 50 MICRON CHROMATOGRAPHY MEDIA; POROS PI 50 MICRON POROS MEDIA (10-30% ETHANOL) NA ENGLISH MSDS 1 / 8

2 Manufacturer Name: Applied Biosystems 850 Lincoln Centre Drive Foster City, CA USA Phone: (650) (USA) Emergency Telephone: (NORTH AMERICA); (INTERNATIONAL, REVERSE CHARGES) Intended Use: For Research Use Only, Not for Use in Diagnostic Procedures 2 HAZARDS IDENTIFICATION Emergency Overview Physical State: Liquid Color: No data available. Odor: No data available. WARNING! Causes eye irritation. Prolonged or repeated contact may dry skin and cause irritation. Combustible liquid and vapor. Potential Health Effects Inhalation: Vapors may cause drowsiness and dizziness. Eye Contact: Irritating to eyes. Exposed individuals may experience eye tearing, redness, and discomfort. Skin Contact: May cause skin irritation. Degreasing to skin. Ingestion: May cause discomfort if swallowed. Chronic Health Effects: Repeated exposure may cause skin dryness or cracking. Target Organ(s): Eye Skin Potential Physical / Chemical Effects: COMBUSTIBLE. Heating will generate vapors which may form explosive vapor/air mixtures. OSHA Regulatory Status: This product is hazardous according to OSHA 29CFR Environment: The product components are not classified as environmentally hazardous. However, this does not exclude the possibility that large or frequent spills can have a harmful or damaging effect on the environment. The product contains a substance which has a photochemical ozone creation potential. 3 COMPOSITION / INFORMATION ON INGREDIENTS General Information: The product contains: Polymer. NA ENGLISH MSDS 2 / 8

3 Chemical Name CAS-No. Concentration* Ethanol % * All concentrations are percent by weight unless ingredient is a gas. Gas concentrations are in percent by volume. This chemical is hazardous according to OSHA/WHMIS criteria. 4 FIRST AID MEASURES Inhalation: Move injured person into fresh air and keep person calm under observation. Get medical attention if any discomfort continues. Eye Contact: Immediately flush with plenty of water for up to 15 minutes. Remove any contact lenses and open eyes wide apart. If irritation occurs, get medical assistance. Skin Contact: Remove contaminated clothes and rinse skin thoroughly with water for at least 15 minutes. If irritation occurs, get medical assistance. Ingestion: Rinse mouth thoroughly with water and give large amounts of milk or water to people not unconscious. Get medical attention if any discomfort continues. 5 FIRE-FIGHTING MEASURES Extinguishing Media: Extinguish with foam, carbon dioxide, dry powder or water fog. Unsuitable Extinguishing Media: Not applicable. Special Fire Fighting Procedures: Use standard firefighting procedures and consider the hazards of other involved materials. Cool containers exposed to heat with water spray and remove container, if no risk is involved. Unusual Fire & Explosion Hazards: During fire, gases hazardous to health may be formed. Solvent vapors may form explosive mixtures with air. Hazardous Combustion Products: Carbon Dioxide, Carbon Monoxide Protective Measures: Selection of respiratory protection for fire fighting: follow the general fire precautions indicated in the workplace. Self-contained breathing apparatus and full protective clothing must be worn in case of fire. Flammability Class: NFPA Rating Fire = 2. 6 ACCIDENTAL RELEASE MEASURES Personal Precautions: Extinguish all ignition sources. Avoid sparks, flames, heat and smoking. Ventilate. Avoid inhalation of vapors and contact with skin and eyes. Wear suitable protective clothing. See Section 8 of the MSDS for Personal Protective Equipment. Spill Cleanup Methods: Remove sources of ignition. Absorb spillage with non-combustible, absorbent material. For waste disposal, see section 13 of the MSDS. Environmental Precautions: Avoid discharge into drains, water courses or onto the ground. NA ENGLISH MSDS 3 / 8

4 Notification Procedures: Inform authorities if large amounts are involved. 7 HANDLING AND STORAGE Handling: Local exhaust is recommended. Use explosion proof electric equipment. The product is combustible, and heating may generate vapors which may form explosive vapor/air mixtures. Do not smoke and do not spray near an open flame or other sources of ignition. Avoid inhalation of vapors and contact with skin and eyes. Wear approved safety goggles. Wear protective gloves and appropriate clothing to prevent skin contact. Observe good industrial hygiene practices. Storage: Follow rules for combustible liquids. Store in closed original container in a dry place. Keep away from heat, sparks and open flame. Keep away from food, drink and animal feeding stuffs. 8 EXPOSURE CONTROLS / PERSONAL PROTECTION Exposure Limits: Chemical Name Source Type Exposure Limits Notes Ethanol ACGIH TWA 1000 ppm Ethanol NIOSH Guide IDLH 3300 ppm Ethanol US. OSHA Table Z-1 TWA 1000 ppm 1900 mg/m³ Consult Canadian Provincial Regulations and/or Mexican Regulations on exposure limits, if applicable. Engineering Controls: Use explosion-proof ventilation equipment. Provide adequate ventilation. Observe Occupational Exposure Limits and minimize the risk of inhalation of vapors. Provide easy access to water supply or an emergency shower. Respiratory Protection: If engineering controls do not maintain airborne concentrations below recommended exposure limits (where applicable) or to an acceptable level (in countries where exposure limits have not been established), an approved respirator must be worn. In the United States of America, if respirators are used, a program should be instituted to assure compliance with OSHA Standard 63 FR 1152, January 8, Seek advice from supervisor on the company's respiratory protection standards. Eye Protection: Wear approved safety goggles. Hand Protection: Wear protective gloves. Be aware that the liquid may penetrate the gloves. Frequent change is advisable. Suitable gloves can be recommended by the glove supplier. Skin Protection: Wear appropriate clothing to prevent repeated or prolonged skin contact. Apron and long sleeves are recommended. Hygiene Measures: Always observe good personal hygiene measures, such as washing after handling the material and before eating, drinking, and/or smoking. Routinely wash work clothing and protective equipment to remove contaminants. 9 PHYSICAL AND CHEMICAL PROPERTIES Color: No data available. Odor: No data available. NA ENGLISH MSDS 4 / 8

5 Odor Threshold: No data available. Physical State: Liquid ph: No data available Melting Point: No data available. Freezing Point: No data available. Boiling Point: No data available. Flash Point: No data available. Evaporation Rate: No data available. Flammability Limit - Upper (%): No data available. Flammability Limit - Lower (%): No data available. Vapor Pressure: No data available. Vapor Density (Air=1): No data available. Specific Gravity: No data available. Solubility in Water: Soluble Solubility (Other): No data available. Partition Coefficient (n-octanol/water): No data available. Autoignition Temperature: No data available. Decomposition Temperature: No data available. Viscosity: No data available. 10 STABILITY AND REACTIVITY Stability: This product is stable under expected conditions of use. Conditions to Avoid: Heat, sparks, flames. May attack some plastics, rubber and coatings. Incompatible Materials: Strong oxidizing agents. Hazardous Decomposition Products: At Elevated Temperatures: Carbon Dioxide, Carbon Monoxide 11 TOXICOLOGICAL INFORMATION Specified Substance(s) Acute Toxicity: Component Chemical Name Ethanol Ethanol Test Results Inhalation LC50 (10 hour(s), Rat): ppm (m) Oral LD50 (Rat): 7060 mg/kg Listed Carcinogens: Chemical Name IARC NTP OSHA ACGIH Ethanol Not Listed Not Listed Not Listed A4 IARC: 1 = Carcinogenic to Humans; 2A = Probably Carcinogenic to Humans; 2B = Possibly Carcinogenic to Humans; 3 = Not classifiable as to carcinogenicity to humans; 4 = Probably not carcinogenic to humans; Not listed = Not evaluated by IARC. ACGIH: A1 = Confirmed Human Carcinogen; A2 = Suspected Human Carcinogen; A3 = Confirmed Animal Carcinogen; A4 = Not classifiable as a human carcinogen; A5 = Not suspected to be a human carcinogen; Not listed = Not evaluated by ACGIH. Product Information Acute Toxicity: Causes eye irritation. May cause skin irritation. NA ENGLISH MSDS 5 / 8

6 Chronic Toxicity: Repeated exposure may cause skin dryness or cracking. 12 ECOLOGICAL INFORMATION Ecotoxicity: The product components are not classified as environmentally hazardous. However, this does not exclude the possibility that large or frequent spills can have a harmful or damaging effect on the environment. Mobility: The product is water soluble and may spread in water systems. The product contains organic solvents which will evaporate easily from all surfaces. Persistence and Degradability: No data available. Bioaccumulation Potential: No data available. Other Adverse Effects: The product contains a substance which has a photochemical ozone creation potential. 13 DISPOSAL CONSIDERATIONS General Information: Dispose of waste and residues in accordance with local authority requirements. Disposal Methods: No specific disposal method required. Container: Since emptied containers retain product residue, follow label warnings even after container is emptied. 14 TRANSPORT INFORMATION DOT Non hazardous for transport. This material is not subject to the requirements of 49CFR HMR per Section (e). TDG Non hazardous for transport. This material is not subject to the requirements of thetdg Regulations - Schedule 1 for UN1170, Ethanol. IATA Non hazardous for transport. This material is not subject to the requirements of ICAO/IATA DGR per Special Provision A58. IMDG Non hazardous for transport. This material is not subject to the requirements of IMDG Code per Special Provision REGULATORY INFORMATION Canadian Controlled Products Regulations: This product has been classified according to the hazard criteria of the Canadian Controlled Products Regulations, Section 33, and the MSDS contains all required information. WHMIS Classification: B3, D2B Mexican Dangerous Statement: This product is dangerous according to Mexican regulations. NA ENGLISH MSDS 6 / 8

7 Inventory Status: US TSCA inventory Status: All the components of this substance are listed on or are exempt from the inventory. For purposes of 40 CFR , this product is for Research and Development (R&D) Use Only. US Regulations CERCLA Hazardous Substance List (40 CFR 302.4): Chemical Name Ethanol RQ 100 lbs SARA Title III Section 302 Extremely Hazardous Substances (40 CFR 355, Appendix A): Not regulated. Section 311/312 (40 CFR 370): X Acute (Immediate) Chronic (Delayed) X Fire Reactive Pressure Generating Section 313 Toxic Release Inventory (40 CFR 372): Not regulated. Clean Air Act (CAA) Section 112(r) Accidental Release Prevention (40 CFR ): Not regulated. Clean Water Act Section 311 Hazardous Substances (40 CFR 117.3): Not regulated. Drug Enforcement Act: Not regulated. TSCA: TSCA Section 4(a) Final Test Rules & Testing Consent Orders: Not regulated. TSCA Section 5(a)(2) Final Significant New Use Rules (SNURs) (40CFR 721, Subpt. E): Not regulated. TSCA Section 5(e) PMN-Substance Consent Orders: Not regulated. TSCA Section 12(b) Export Notification (40 CFR 707, Subpt. D): Not regulated. State Regulations California Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65): Not regulated. Massachusetts Right-To-Know List: Ethanol Michigan Critical Materials List (Michigan Natural Resources and Environmental Protection Act (Act. 451 of 1994)): Not regulated. Minnesota Hazardous Substances List: Ethanol New Jersey Right-To-Know List: Ethanol NA ENGLISH MSDS 7 / 8

8 Pennsylvania Right-To-Know List: Ethanol Rhode Island Right-To-Know List: Ethanol 16 OTHER INFORMATION HAZARD RATINGS Health Hazard Fire Hazard Instability Special Hazard NFPA Hazard rating: 0 - Minimal; 1 - Slight; 2 - Moderate; 3 - Serious; 4 - Severe NFPA Label colored diamond code: Blue - Health; Red - Flammability; Yellow - Instability; White - Special Hazards Health Hazard Flammability Physical Hazard Personal Protection HMIS B Hazard rating: 0 - Minimal; 1 - Slight; 2 - Moderate; 3 - Serious; 4 - Severe Personal Protection codes: B - Safety Glasses, Gloves HMIS Label colored bar code: Blue - Health; Red - Flammability; Orange - Physical Hazards; White - Special Disclaimer: This MSDS has been prepared using information from sources considered technically reliable. It should not be relied upon as a product specification. The company makes no warranty of any kind, express or implied, concerning the safe use of this material in your process or in combination with other chemical substances. Every user of the product is responsible for evaluating its own processes and conditions of use and selecting appropriate protective measures for employee exposure. NA ENGLISH MSDS 8 / 8