Material Safety Data Sheet

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1 Material Safety Data Sheet NFPA HMIS Personal Protective Equipment 2 0 Health Hazard Fire Hazard 2 0 See Section 5. Section. Chemical Product and Company Identification Common Name/ Trade Name Manufacturer Commercial Name(s) Synonym Chemical Name Triamcinolone acetonide SPECTRUM CHEMICAL MFG. CORP S. SAN PEDRO STREET GARDENA, CA Fluoro-,2-dihydroxy-6,7-[-methylethylidenebis(oxy)pregna-,4 Catalog Number(s). CAS# RTECS TSCA CI# YY27, TR TU IN CASE OF EMERGENCY CHEMTREC (24hr) Page Number: TSCA 8(b) inventory: Triamcinolone acetonide Chemical Family Chemical Formula Supplier C24H3FO6 SPECTRUM CHEMICAL MFG. CORP S. SAN PEDRO STREET GARDENA, CA CALL (30) Section 2.Composition and Information on Ingredients Name CAS # Exposure Limits TWA (mg/m 3 ) STEL (mg/m 3 ) CEIL (mg/m 3 ) % by Weight ) Triamcinolone acetonide Toxicological Data on Ingredients Triamcinolone acetonide LD50: LC50: Section 3. Hazards Identification Potential Acute Health Effects Potential Chronic Health Effects Hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Slightly hazardous in case of skin contact (permeator). CARCINOGENIC EFFECTS: MUTAGENIC EFFECTS: TERATOGENIC EFFECTS: DEVELOPMENTAL TOXICITY: PROVEN The substance is toxic to the reproductive system. Repeated or prolonged exposure to the substance can produce target organs damage.

2 Triamcinolone acetonide Page Number: 2 Section 4. First Aid Measures Eye Contact Check for and remove any contact lenses. Do not use an eye ointment. Seek medical attention. Skin Contact Serious Skin Contact Inhalation After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing before reusing. Wash with a disinfectant soap and cover the contaminated skin with an anti-bacterial cream. Seek medical attention. Allow the victim to rest in a well ventilated area. Seek immediate medical attention. Serious Inhalation Ingestion Serious Ingestion Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention. Section 5. Fire and Explosion Data Flammability of the Product Auto-Ignition Temperature Flash Points Flammable Limits Products of Combustion Fire Hazards in Presence of Various Substances May be combustible at high temperature. These products are carbon oxides (CO, CO2), halogenated compounds. Explosion Hazards in Presence of Various Substances Risks of explosion of the product in presence of mechanical impact: Risks of explosion of the product in presence of static discharge: Fire Fighting Media and Instructions Fire Hazards Explosion Hazards SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Section 6. Accidental Release Measures Small Spill Large Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.

3 Triamcinolone acetonide Page Number: 3 Section 7. Handling and Storage Precautions Storage Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If you feel unwell, seek medical attention and show the label when possible. Avoid contact with skin and eyes Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly closed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heat and away from strong oxidizing agents. Section 8. Exposure Controls/Personal Protection Engineering Controls Personal Protection Personal Protection in Case of a Large Spill Exposure Limits Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Splash goggles. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Section 9. Physical and Chemical Properties Physical state and appearance Solid. Odor Molecular Weight ph (% soln/water) g/mole Taste Color Boiling Point Decomposes. Melting Point 293 C (559.4 F) Critical Temperature Specific Gravity Vapor Pressure Not applicable. Vapor Density Volatility Odor Threshold Water/Oil Dist. Coeff. Ionicity (in Water) Dispersion Properties Solubility Section 0. Stability and Data Stability Instability Temperature Conditions of Instability Incompatibility with various substances The product is stable.

4 Triamcinolone acetonide Page Number: 4 Corrosivity Non-corrosive in presence of glass. Corrosivity Polymerization No. Section. Toxicological Information Routes of Entry Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Toxicity to Animals Chronic Effects on Humans other Toxic Effects on Humans Eye contact. Inhalation. Ingestion. LD50: LC50: DEVELOPMENTAL TOXICITY: PROVEN The substance is toxic to the reproductive system. Hazardous in case of skin contact (irritant), of ingestion, of inhalation. Slightly hazardous in case of skin contact (permeator). Animal: embryotoxic, foetotoxic, passes through the placental barrier. Menstrual disorders in human. Section 2. Ecological Information Ecotoxicity BOD5 and COD Products of Biodegradation Toxicity of the Products of Biodegradation the Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The products of degradation are more toxic. Section 3. Disposal Considerations Waste Disposal Section 4. Transport Information DOT Classification Identification Not a DOT controlled material (United States). Not applicable. Special Provisions for Transport Not applicable.

5 Triamcinolone acetonide Page Number: 5 DOT Section 5. Other Regulatory Information and Pictograms Federal and State Regulations TSCA 8(b) inventory: Triamcinolone acetonide California Proposition 65 Warnings Other Regulations OSHA: Hazardous by definition of Hazard Communication Standard (29 CFR ). Other Classifications WHMIS (Canada) DSCL (EEC) CLASS D-2A: Material causing other toxic effects (VERY TOXIC). R36/38- Irritating to eyes and skin. HMIS (U.S.A.) Health Hazard Fire Hazard Personal Protection 2 0 E National Fire Protection Association (U.S.A.) Health 2 0 Flammability Specific hazard WHMIS (Canada) DSCL (Europe) TDG (Canada) ADR (Europe) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Wear appropriate respirator when ventilation is inadequate.

6 Triamcinolone acetonide Page Number: 6 Splash goggles. Section 6. Other Information MSDS Code References Other Special Considerations T3780 Validated by Sonia Owen on 8/29/2006. Verified by Sonia Owen. Printed 9/4/2006. CALL (30) Notice to Reader All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.

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