Hyaluronic Acid Dermo Active Cream

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1 Hyaluronic Acid Dermo Active Cream Technical Information Retail reference : Reference : B0050/1 50 ml / 1.75 fl.oz Tube flip top + box Professional reference : Reference : B0150/1 Airless bottle 150 ml / 5 fl.oz with high-tech creams and fluid for face enriched in highly concentrated active ingredients. With incredible textures, they offer pure moments of well-being. Hyaluronic Acid Dermo Active Cream Anti-Ageing Cream Dry Skin Brings long-lasting hydration* Reduces the appearance of wrinkles and fine lines Helps to tense and firm the skin No coloring agent No perfume Soft and unctuous, the Hyaluronic Acid Dermo Active Cream strengthens the cells metabolism, brings long-lasting hydration* and comfort to the skin as well as a boosting effect, helping to reduce the appearance of wrinkles and fine lines and firm the epidermis. The skin just feels younger! Directions for Use Massage gently onto face and neck after cleansing morning and/or evening. For better results, apply the Hyaluronic Acid Dermo Active Complex before the cream. * Upper layers of the epidermis

2 Hyaluronic Acid Dermo Active Cream Active Principles % Claims Hyaluronic Acid Complex 10,00% It is one of the chief components of the extracellular matrix. It contributes significantly to cell proliferation and migration, and locks moisture* into the extracellular matrix, keeping collagen and elastin moist and promoting a youthful appearance. Literally acting like a sponge in the skin, the sodium hyaluronate can reach a level of water mobilization of up to 20 times its own weight. So it allows maintaining the cutaneous moisturization*, the water loss being the early symptom of the cutaneous ageing. Hyaluronic acid is also a major component of skin, where it is involved in tissue repair. When skin is excessively exposed to UVB rays, it becomes inflamed (sunburn) and the cells in the dermis stop producing as much hyaluronan, and increase the rate of its degradation. In this formula, several hyaluronic acids with different molecular weight (HW, MW and LW) have been used in order to obtain an optimal and complete efficacy : Sodium Hyaluronate HW MW LW Molecular weight range (in Da) Applications Anti-dehydration*, film forming & tensing effect Tensing effect, long-lasting hydration* Fastrack hydration* Myrtus Communis Complex Efficacy test available 4,00% Obtained from myrtle, prized in antiquity for its rejuvenating virtues, this active ingredient slows the expression of the senescence factors down, limits dermal degeneration and increases cells lifetime by: - favoring the synthesis of SIRT-1, universal proteins involved in cell longevity; - regulating and reorganizing caveolines-1, proteins deeply involved in cell-cell communication; - inhibiting the glycation of collagen, an irreversible reaction responsible for the tissue rigidification. Ingredients WATER (AQUA), CYCLOPENTASILOXANE, GLYCERIN, CAPRYLIC/CAPRIC TRIGLYCERIDE, CETEARYL ETHYLHEXANOATE, DIMETHICONE, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, LAURYL LAURATE, METHYL METHACRYLATE CROSSPOLYMER, PROPYLENE GLYCOL, CETEARYL ALCOHOL, BEHENETH-25, HYDROGENATED POLYISOBUTENE, VITIS VINIFERA (GRAPE) SEED OIL, POLYSILICONE-11, COCO-GLUCOSIDE, DIMETHICONE CROSSPOLYMER, SILICA, CARBOMER, TOCOPHERYL ACETATE, TRIETHANOLAMINE, PHENOXYETHANOL, HYDROLYZED MYRTUS COMMUNIS LEAF EXTRACT, CHLORPHENESIN, SODIUM HYALURONATE, CYCLOTETRASILOXANE, METHYLISOTHIAZOLINONE, ETHYLHEXYLGLYCERIN. * Upper layers of the epidermis

3 Collagen & Elastin Dermo Active Cream Technical Information Retail reference : Reference : B0050/7 50 ml / 1.75 fl.oz Tube flip top + box Professional reference : Reference : B0150/7 Airless bottle 150 ml / 5 fl.oz with high-tech creams and fluid for face enriched in highly concentrated active ingredients. With incredible textures, they offer pure moments of well-being. Collagen & Elastin Dermo Active Cream Wrinkles Filler Cream Dry to Normal Skin Helps to moisturize* and heal the skin Improves skin elasticity and tonifies it Promotes youthful appearance No coloring agent No perfume Thanks to its high concentration of active ingredients, the Collagen & Elastin Dermo Active Cream is a must-have in the process of cells regeneration and skin elasticity improvement. Light and melting, it helps to reduce significantly the appearance of wrinkles and fine lines. Directions for Use Massage gently onto face and neck after cleansing morning and/or evening. For better results, apply the Collagen & Elastin Dermo Active Complex before the cream. * Upper layers of the epidermis

4 Collagen & Elastin Dermo Active Cream Active Principles % Claims Marine Collagen Complex 6,00% The marine collagen is mainly used for its tonifying and moisturizing* properties but also like an activator of the cells growth and in order to improve skin elasticity. ADN Gel Complex Efficacy tests available Hydrolyzed Elastin Complex 6,00% Particularly adapted to products for the treatment of skin ageing, this ADN gel is a remarkably stable product with both moisturizing* and healing properties. The moisturizing* properties logically result from its richness in hydrophilic groups which bind a large amount of water. As for the healing properties, DNA may intervene as a synthesis of ATP. 5,00% Concentrated in amino-acid and working by strengthening of tissues support, the marine elastin contributes to slow down cutaneous ageing. Hyaluronic Acid Complex 3,00% It is one of the chief components of the extracellular matrix. It contributes significantly to cells proliferation and migration, and locks moisture into the extracellular matrix, keeping collagen and elastin moist and promoting a youthful appearance. Literally acting like a sponge in the skin, the sodium hyaluronate can reach a level of water mobilization of up to 20 times its own weight. Thus, it allows maintaining the cutaneous hydration*, the water loss being the early symptom of cutaneous ageing. Hyaluronic acid is also a major component of skin, where it is involved in tissue repair because when skin is excessively exposed to UVB rays, it becomes inflamed (sunburn) and the cells in the dermis stop producing as much hyaluronan, and increase the rate of its degradation. Ingredients WATER (AQUA), GLYCERIN, PROPYLENE GLYCOL, PENTAERYTHRITYL TETRAETHYLHEXANOATE, HYDROLYZED ELASTIN, CYCLOPENTASILOXANE, C12-15 ALKYL BENZOATE, OCTYLDODECANOL, PEG-40 STEARATE, GLYCERYL STEARATE, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, BUTYROSPERMUM PARKII (SHEA BUTTER), PHYTOSTERYL CANOLA GLYCERIDES, METHYL METHACRYLATE CROSSPOLYMER, HDI/TRIMETHYLOL HEXYLLACTONE CROSSPOLYMER, SACCHARIDE ISOMERATE, TALC, CETYL ALCOHOL, DIMETHICONE, STEARETH-2, PANTHENOL, PHENOXYETHANOL, TRIETHANOLAMINE, BENZOPHENONE-4, DNA, XANTHAN GUM, CARBOMER, CHLORPHENESIN, SOLUBLE COLLAGEN, TETRASODIUM EDTA, SODIUM HYALURONATE, POTASSIUM SORBATE, SILICA, METHYLISOTHIAZOLINONE, TRISODIUM EDTA, CITRIC ACID, SODIUM CITRATE, SODIUM HYDROXIDE, TRISODIUM NTA. * Upper layers of the epidermis

5 Acetyl Hexapeptide Dermo Active Cream Technical Information Retail reference : Reference : B0050/5 50 ml / 1.75 fl.oz Tube flip top + box Professional reference : Reference : B0150/5 Airless bottle 150 ml / 5 fl.oz with high-tech creams and fluid for face enriched in highly concentrated active ingredients. With incredible textures, they offer pure moments of well-being. Acetyl Hexapeptide Dermo Active Cream Tensing Cream Normal to Dry Skins Helps to firm, tense and smooth the skin Reduces the appearance of wrinkles Slows down apparent skin ageing No coloring agent No perfume With an immediate and long term tensing effect, the Acetyl Hexapeptide Dermo Active Cream is essential to the well-being of a more luminous and firmer skin. Its softness, unction and efficiency make the apparent skin ageing just fade away. Wrinkles and fine lines belong to the past! Directions for Use Massage gently onto face and neck after cleansing morning and/or evening. For better results, apply the Acetyl Hexapeptide Dermo Active Complex before the cream.

6 Acetyl Hexapeptide Dermo Active Cream Active Principles % Claims ACETYL HEXAPEPTIDE-8 0,005% It reduces facial wrinkles depth caused by repeated facial movements, especially on the forehead and around the eyes. Furthermore, it can prevent apparent skin aging induced by repeated facial movements caused by excessive catecholamine release. DIMETHYLAMINOETHANOL 2,00% Natural compound near to choline, which brings a firming and tensing effect to the skin. The DMAE is not able to smooth out the facial wilt but it can slow down the progression of this phenomenon. AVENA SATIVA (OAT) KEMEL COMPLEX Efficacy tests available 4,00% This active ingredient is a 100% natural sugar tensor purified fraction of oat polysaccharides. It procures a tensor effect that is visibly and immediately perceptible by the consumer because it absorbs to the surface of the skin and forms a viscoelastic, cohesive and continuous biological film. In addition, it provides a short and long-term antiwrinkle effect. Thus, an efficacy study has showed that this active ingredient significantly reduces the number of wrinkles, the total wrinkled surface and the total length of wrinkles. Ingredients WATER (AQUA), CYCLOPENTASILOXANE, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, CYCLOHEXASILOXANE, C12-15 ALKYL BENZOATE, DIMETHYLAMINOETHANOL TARTRATE, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL, POLYSILICONE-11, DIMETHICONE, GLYCERIN, SODIUM CHLORIDE, PEG/PPG-18/18 DIMETHICONE, PROPYLENE GLYCOL, PHENOXYETHANOL, METHYLISOTHIAZOLINONE, ETHYLHEXYLGLYCERIN, ACETYL HEXAPEPTIDE-8.

7 Arbutin Dermo Active Cream Technical Information Retail reference : Reference : B0050/4 50 ml / 1.75 fl.oz Tube flip top + box Professional reference : Reference : B0150/4 Airless bottle 150 ml / 5 fl.oz with high-tech creams and fluid for face enriched in highly concentrated active ingredients. With incredible textures, they offer pure moments of well-being. Arbutin Dermo Active Cream Whitening Cream Oily Skin and/or with pigmentation problems Brings immediate and long-term lightening effects Minimizes the appearance of blemishes Brings moisturization* No coloring agent No perfume Specially formulated to bring an immediate and long term brightening effect, the Arbutin Dermo Active Cream actively contributes to even the skin tone and minimize the appearance of pigmentation problems while moisturizing* the epidermis. Its soft and light texture makes the application easy and very pleasant for a real moment of pureness! Directions for Use Massage gently onto face and neck after cleansing morning and/or evening. For better results, apply the Arbutin Dermo Active Complex before the cream. * Upper layers of the epidermis

8 Arbutin Dermo Active Cream Active Principles % Claims Arbutin 5,00% Natural extract found in bearberry Arctostaphylos uva ursi) plants, Arbutin blocks epidermal melanin biosynthesis by inhibiting enzymatic oxidation of Tyrosine and Dopa structurally. This leads to a skin lightening active that acts faster and more efficiently than existing single components, minimizes liver spots and reduces the degree of skin tanning after UV exposure. Hyaluronic Acid Complex 3,00% Literally acting like a sponge in the skin, the sodium hyaluronate can reach a level of water mobilization of up to 20 times its own weight. So, it allows maintaining the cutaneous hydration*, the water loss being the early symptom of the cutaneous ageing. Natural Glucidic Complex 1,00% regulates effectively the skin hydration*. Indeed, thanks to its particular structure, it drains water like a magnet and captures it, letting it go only via the natural desquamation process. Ingredients WATER (AQUA), ALCOHOL DENAT., CYCLOPENTASILOXANE, ARBUTIN, GLYCERIN, ISONONYL ISONONANOATE, CYCLOHEXASILOXANE, PROPYLENE GLYCOL, DIMETHICONE, PHENYL TRIMETHICONE, TITANIUM DIOXIDE (CI 77891), AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, METHYL METHACRYLATE CROSSPOLYMER, HDI/TRIMETHYLOL HEXYLLACTONE CROSSPOLYMER, SACCHARIDE ISOMERATE, TALC, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, BENZOPHENONE-4, HYDROXYETHYL ACRYLATE/SODIUM ACRYLOYLDIMETHYLTAURATE COPOLYMER, TRIETHANOLAMINE, SQUALANE, CHLORPHENESIN, TETRASODIUM EDTA, POLYSORBATE 60, SODIUM HYALURONATE, SILICA, METHYLISOTHIAZOLINONE, CITRIC ACID, SODIUM CITRATE, SODIUM HYDROXIDE, TRISODIUM NTA. * Upper layers of the epidermis

9 Taurine Dermo Active Cream Technical Information Retail reference : Reference : B0050/6 50 ml / 1.75 fl.oz Tube flip top + box Professional reference : Reference : B0150/6 Airless bottle 150 ml / 5 fl.oz with high-tech creams and fluid for face enriched in highly concentrated active ingredients. With incredible textures, they offer pure moments of well-being. Taurine Dermo Active Cream Revitalizing Cream Normal Skin Helps to revitalize, regenerate and restructure the skin Contains an antioxidant agent which helps to reduce wrinkles depth No coloring agent No perfume A soft and unctuous texture associated to targeted active ingredients : Taurine (stimulating muscles growth and tonus) and Q10 (an antioxydant agent and wrinkles filler). Thus, the Taurine Dermo Active Cream shows energizing and regenerating properties, revitalizing the epidermis and helping reduce wrinkles depth. Directions for Use Massage gently onto face and neck after cleansing morning and/or evening. For better results, apply the Taurine Dermo Active Complex before the cream.

10 Taurine Dermo Active Cream Active Principles % Claims Taurine 3,00% Taurine is an organic acid derivative of the cysteine and the only known naturally occurring sulfonic acid. It is a stabilisator of cell membrane by maintaining the structure, permeability and polarization, and has a revitalizing effect on the skin. COENZYME Q10 0,10% Antioxidant agent, acting in multiple ways to reduce the effects of environmental aggressions to the skin, visible in the reduction of wrinkle depth and a decreased turnover time of the epithelium. BIOCHEMICAL ROLE Coenzyme Q10 is found in the membranes of endoplasmic reticulum, peroxisomes, lysosomes, vesicles, and the inner membrane of the mitochondrion, where it is an important part of the lectron transport chain; there it passes reducing equivalents to acceptors such as Coenzyme Q : cytochrome c - oxidoreductase : CoQH2+ 2 FeIII-cytochrome c CoQ + 2 FeII-cytochrome c Coenzyme Q10 is also essential in the formation of the apoptosome, along with other adapter proteins. The loss of trophic factors activates pro-apoptotic enzymes, causing the breakdown of mitochondria. ANTIOXIDANT ROLE OF COENZYME Q10 IN THE BODY Apart from being a cofactor in the mitochondrial electron transport chain, Coenzyme Q10 in its reduced form (ubiquinol or CoQ10 H2) serves as an important antioxidant in both mitochondria and lipid membranes, where it protects the body's cells in their battle against the destructive effects of free-radicals. Coenzyme Q10 is essential in vitamin E regeneration. Ubiquinol inhibits protein and lipid oxidation in cell membranes, and helps to minimize oxidative injury to DNA. Coenzyme Q10 is an integral part of the respiratory chain and thereby located exactly where the free-radicals are generated, in the mitochondria. These endogeneously produced free-radicals are considered an import factor of the aging process. Ingredients WATER (AQUA), CYCLOPENTASILOXANE, DIMETHICONE/VINYL DIMETHICONE CROSSPOLYMER, CYCLOHEXASILOXANE, TAURINE, C12-15 ALKYL BENZOATE, PRUNUS AMYGDALUS DULCIS (SWEET ALMOND) OIL, POLYSILICONE-11, DIMETHICONE, GLYCERIN, SODIUM CHLORIDE, PEG/PPG-18/18 DIMETHICONE, PROPYLENE GLYCOL, TOCOPHERYL PEG-40 HYDROGENATED CASTOR OIL, METHYLISOTHIAZOLINONE.

11 Sebo-Normalizing Dermo Active Fluid Technical Information Retail reference : Reference : SEBO/FLUID50 50 ml / 1.75 fl.oz Glass bottle with pipette + box with high-tech creams and fluid for face enriched in highly concentrated active ingredients. With incredible textures, they offer pure moments of well-being. Sebo-Normalizing Dermo Active Fluid Helps to normalize sebum production Purifies the epidermis Beautifies the appearance of the skin Oily to acne prone skin Fresh and light, this Sebo-Normalizing Fluid combines efficiency and well-being perfectly. It brings a sensation of freshness to the epidermis and normalizes the sebum production. This fluid helps to reduce the imperfections of the complexion and restores the balance of the skin. It leaves the skin softer and smoother. The complexion is unified. Directions for use Massage gently onto face and neck after cleansing morning and/or evening. For better results, apply the Sebo-Normalizing Cream Mask and Serum before the Fluid.

12 Sebo-Normalizing Dermo Active Fluid Active Principles % Claims Evermat 3,00% Evermat is an association of Enantia extract sebum secretion by : - Regulation of proliferation and differentiation of sebocytes. - Inhibition of the activity of 5-alpha reductase Efficiency tests show that this active refines skin texture and reduces significantly the brightness. Ingredients WATER (AQUA), CYCLOPENTASILOXANE, ALCOHOL DENAT., ISONONYL ISONONANOATE, BUTYLENE GLYCOL, GLYCERIN, PROPYLENE GLYCOL, PEG-60 GLYCERYL ISOSTEARATE, FRAGRANCE (PARFUM), METHYL METHACRYLATE CROSSPOLYMER, AMMONIUM ACRYLOYLDIMETHYLTAURATE/VP COPOLYMER, DIPROPYLENE GLYCOL, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, TRIETHANOLAMINE, DECYLENE GLYCOL, ENANTIA CHLORANTHA BARK EXTRACT, BENZOPHENONE-4, HYDROXYPROPYL GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE, LIMONENE, TETRASODIUM EDTA, LINALOOL, HYDROXYISOHEXYL 3-CYCLOHEXENE CARBOXALDEHYDE, CITRONELLOL, HYDROXYCITRONELLAL, METHYLISOTHIAZOLINONE, SODIUM HYDROXIDE, OLEANOLIC ACID, DC RED 33 (CI 17200), TRISODIUM NTA.

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