NTC. Portfolio. October 2017

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1 NTC Portfolio October 2017

2 A bit of history. 2

3 We originate from two Business-To-Business organizations, PH&T SpA and NTC Srl, both with Headquarters in Milan, Italy. In 2015 both companies have been acquired by an Italian investment fund, Wise SGR, and were merged into NTC Srl in Jan Our portfolio of products is made of drugs, nutraceuticals and medical devices. We are now investing significantly in development and our pipeline is getting richer in particular areas like ophthalmology, gastro-metabolism, pediatrics and pharmacy. We are looking forward to accelerate our growth also through the acquisitions of products, technologies and companies. 3

4 NTC, who we are. We are a pharmaceutical company that develops products on our initiative or on request. We innovate on several dimensions: new products supported by relevant clinical trials new technologies, to help patient compliance and so favor personalized treatment new packaging solutions to better serve the patients We invest substantially in R&D, and we sustain independent research too. We quickly develop, we know where to manufacture, we register and sell. We own strong regulatory skills about drugs, medical devices and nutraceuticals. We supply through sourcing from CMOs. We have a good network of contacts. We sell in more than 70 countries to north to 200 clients. About 70% of our sales are in EMEA. We sell also in Asia, Australia, Africa, Middle East, Canada. We are expanding in America. In 2016 we signed our first deal in the US. In 2017 we signed our first deal in LATAM. 4

5 Our organization. 5

6 Management with vast experience and strong success stories in large multinationals like Novartis, Pfizer, Alcon, Bausch+Lomb, Gilead, Walt Disney. We hold a significant experience in VC and PE M&A, and capabilities to integrate smoothly new organizations. Smart R&D Team to foster innovation: 7 people devoted to conceptualize new projects and to manage project development, leveraging large KOL network/consultants. Experienced Regulatory Team: more than 10 people with international experience in drugs, medical devices and nutraceuticals. Skilled CMO Group: 3 people dedicated to interact with CMOs and audit. Strong Market Reach: more than 10 BD&L professionals (internal and partners) in the field. Kind and professional Customer Service: 6 dedicated people. NTC supplies pharmaceutical products in line with high quality standard. The NTC Quality team supports the clients leveraging a certified Quality System. Technology supports NTC on multiple dimension: NTC customer service to track the orders, Italian Innovation App to present our updated innovation. 6

7 Some of our partners. 7

8 Our core areas today and tomorrow. Ophthalmology Gastro - Metabolism Pediatrics OTC - Pharmacy Gynecology/Urology Onco - CNS Respiratory/Allergy TODAY TOMORROW 8

9 Ophthalmology. 9

10 Available for deals now DRY EYE GEL/OINTMENTS BIOTRANSFORMERS CLEANING BLEPHARITIES 0.2%, 0.4% Hyaluronic Acid in single dose 0.2%, 0.4% Day & Night combo box in single dose 0.1%, 0.15%, 0.2%, 0,4% Hyaluronic Acid in multi dose preservative free 0.2%, 0.4% Hyaluronic Acid in multi dose with preservative Hyaluronic Acid combinations in multi dose preservative free: 0.2% with Red fruits and Chamomile 0,2% Hyaluronic Acid with Amino Acids 0.4% with Levocarnitine and Zinc 0.4% with Levocarnitine, Zinc and castor oil 0.5%, 1% Carboxymethylcellulose in multi dose with preservative and single dose 0.5%, 1% Carboxymethylcellulose in multi dose (preservative free) 0.3% Hydroxypropylmethyl cellulose in multi dose preservative free 0.2% Carbomer, Nighttime gel 3% Carbomer + 5% Dexpanthenol, gel plus 0.4% Hyaluronic Acid, Isotonic gel and Ointment 0.4% Hyaluronic Acid + 5% Sodium chloride, Hypertonic gel and Ointment 0.4% Hyaluronic Acid Hypotonic gel Wipes with Hyaluronic acid and Chamomile (periocular hygiene) Wipes with Terpinen-4-ol 0.5% + Hyaluronic acid 0.15% Wipes with Terpinen-4-ol 0.5% + Hyaluronic acid 0.15% + warming compress 10

11 Available for deals now DRY AMD Retinorm gel (based on the AREDS 2 study) Retinorm liquid drink (based on the AREDS 2 study) Retinorm capsules (based on the AREDS 2 study) VITREAL TROPHISM Vitreonorm capsules ALLERGY Lertal Tablets (Perilla + Quercetin + Vit D3) Lertal Spray (Hyaluronic Acid, Perilla, Lyposomes) ANTIBIOTICS Levofloxacin multi dose Ofloxacin multi dose, single dose ANTI-INFLAMMATORIES Diclofenac single dose preservative free Dexamethasone single dose preservative free 11

12 Available for deals now GLAUCOMA Dorzolamide + Timolol, multidose Latanoprost multidose Latanoprost + Timolol, multidose Travoprost multidose Travoprost + Timolol multidose Bimatoprost 0.03% multidose preservative free SPECTACLES for adults UV-A, UV-B, mirrored, to be combined in a Kit for Refractive Surgery together with Dry Eye, Wipes, Anti-inflammatory, Antibiotics SPECTACLES for kids Anallergic, innovative, sport line 12

13 Available in a next future ANTIBIOTICS PREMIUM Levofloxacin slow release (O.D.) Levofloxacin + Dexamethasone Levofloxacin + NSAID Tobramycin spray moist (Innovative Device) CHRONIC INFLAMMATION Budesonide + Hyaluronic Acid (Preservative free) DIAGNOSTIC Tropicamide spray most (Innovative Device) PERIOCULAR DISINFECTANT TiAB active against Gram+ and Gram- DRY EYE Hyaluronic Acid and Amino Acids spray-moist (Innovative Device) 13

14 Gastro-Metabolism. 14

15 Available for deals now DYSPEPSIA DIARRHEA CONSTIPATION PROBIOTICS LIPID DISORDERS ANTIOXYDANT HEPATIC USE NEPHROLOGY CANKER SORES Simethicone softgel capsules for dyspeptic disorders Simethicone Simethicone in oil Simethicone + active carbon in tabs for aerophagy and colics Diosmectite and prebiotic fibers in sachet for acute and chronic diarrhea Macrogol 4000 sachets Physiomanna (Baby, Fibra, Lax Depur) The power of 5 + vitamins during and after antibiotics treatment The power of 1 (Symethicone + Sacch. Boulardii) during antibiotic treatment Omega 3 drug (1g) L-Glutathione sublingual (100 mg; 250 mg) Paricalcitol: drug vials/ampoules for vit D deficiencies and secondary parathyroidism in patients with kidney failure (nephrology) Hyaluronic Acid + Rosa Damascena 15

16 Pediatry. 16

17 Available for deals now IRON SUPPLEMENTS PROBIOTICS CONSTIPATION GAS/StomPAIN DERM IRRIT. DERMATOLOGY WIPES ALLERGY DRY COUGH ANTIBIOTICS CANKER SORES Turbofer (pyrophosphate microencapsulated highly absorbable iron drops odourless, tasteless). The power of 5 + vitamins during and after antibiotics treatment Treatment and prevention (building) in infants with Bifidumbacterium lactis Physiomanna Baby Drops: Simethicone Hyaluronic acid + Chamomile foam TiAB cream, spray Hyaluronic acid with chamomile and euphrasia Lertal Spray (Hyaluronic acid, perilla seeds extract, Lyposomes) Tux Gel (Sorbygel technology) Levofloxacine multi dose Hyaluronic Acid +Rosa Damascena 17

18 Available in a next future BIOMA Large program on Bioma supplementation (atopic dermatitis; intestinal flora) EYE ANTIBIOTICS PREMIUM Tobramycin (innovative device) Levofloxacine + Dexamethasone Levofloxacine Slow Release 18

19 Respiratory/Allergy. 19

20 Available for deals now MUCOLITICS Sea Water and Dexpanthenol ALLERGY Lertal tablets (perilla + quercetin + vit D3) Lertal Spray (Hyaluronic acid, perilla seeds extracts, lyposomes) ASTHMA Turbospin: dry powder inhalher available for multiple asthma drugs RHINITIS Mometasone spray Hyaluronic acid + Amino acids 20

21 Gynecology, Urology. 21

22 Available for deals now VAGINAL CARE IRON DEFICIENCY MENOPAUSE CONSTIPATION IN PREGNANCY NASAL CONGESTION IN PREGNANCY Vaginal ovules and bottles for the treatment of dryness (Hyaluronic acid and boric acid both with TTO) Vaginal gel (Hyaluronic acid and other ingredients) (lubricate and restore vaginal normal conditions and avoid dryness) Vaginal bottle with «hydrogen peroxyde» (antiseptic effect) Vaginal soft gel capsules, gel tube, gel sachets with silver ion Turbofer (microencapsulated iron sachet) Talitha Quiet (sublingual trans-resveratrol + vit E, D 3, B 6, B 12 ) «well being» Physiomanna LaxDepur; Physiomanna Fibra Sea Water+ Dexpanthenol Available in a next future VAGINAL INFECTIONS Combo treatment (oral/local) 22

23 OTC/Pharmacy. 23

24 Available for deals now BIOMA GAS/StomPAIN DRY EYE WIPES ALLERGY IRON DEFICIENCY MENOPAUSE ULCER and WOUNDS CANKER SORES Sachets, capsules, drinkable vials, drops - Lactobacillus acidophilus and Saccharomyces Boulardii; Lactobacillus + vitamins Drops: Symethicone CMC, HPMC in MD (preserved) (price sensitive strategy) Day&Night (in multidose preservative free; in single dose) Medical devices, also with Tea Tree Oil derivatives for blepharitis Lertal Spray (Hyaluronic acid, perilla seeds extract, Lyposomes) Turbofer (microencapsulated iron sachet) Talitha Quiet (sublingual trans-resveratrol + vit E, D 3, B 6, B 12 ) «well being» TiAB (active silver ions): it stands for Titanium, Silver, Benzalkonium. Chemical complex with antibacterial action (Spray, Gyn Softgel Capsule, Derm Cream, Gel) dry spray with kaolin, used to dry wounds Hyaluronic acid +Rosa Damascena 24

25 Supportive Care. 25

26 Available for deals now ULCER and WOUNDS CONSTIPATION TiAB (active silver ions): it stands for Titanium, Silver, benzalkonium. Chemical complex (with bacterial action) (Spray, Gyn Softgel Capsule, Derm Cream, Gel) dry spray with kaolin, used to dry wounds Physiomanna Lax Depur Available in a next future SUPPORTIVE CARE Food supplement for cachexia Probiotics for mucositis 26

27 This document is distributed for informational purposes only. It is exclusively for internal use of NTC and partners. Unauthorized use, disclosure or reproduction is prohibited. ntc S.r.l. Con Socio Unico Sede operativa via dei Gracchi, Milano Sede legale via Luigi Razza, Milano Tel Fax

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