The expert. dermatology. cosmeceutical care

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1 The expert in aesthetic dermatology cosmeceutical care

2 The expert in aesthetic dermatology ESSENTIAL ACTIONS Dermaceutic Laboratoire is the partner of choice for over 30,000 aesthetic dermatology specialists throughout the world. One of the first laboratories to develop products using ingredients such as hyaluronic acid, stabilized vitamin C, and glycolic acid (now standard ingredients in skincare), Dermaceutic has led the cosmeceutical industry in the discovery of effective combinations of ingredients for use in aesthetic dermatology. The efficacy of Dermaceutic s cosmeceutical and peel treatment protocols is supported by extensive clinical trials, and the company s collaboration with industryleading practitioners from around the globe. 1 PREPARATORY EXFOLIATION PURIFY RESTORE PREVENT Cleanser 5 Gentle Exfoliant Foamer 15 Exfoliating Foam Mask 15 Oil Reducing Mask stimulate Light Ceutic Skin Toning Night Cream Turn Over Stimulating Night Cream 2 post 3 EXPERT treatment care TREATMENT Hyal Ceutic Intense Moisturizer Regen Ceutic Skin Recovery Cream K Ceutic Post-Treatment Cream PROTECT Sun Ceutic Anti-Aging Sun Protection C25 Cream Antioxidant Concentrate TARGET Yellow Cream Dark Spot Concentrate TARGET Post-Peel Treatment Spot Cream Depigmenting Cream TREATMENT STRENGTH Mild Medium Strong

3 purify Cleanser 5 Gentle Exfoliant Gentle Exfoliating Lotion Removes impurities and dead cells, and gently purifies the skin. Cleanser 5 is recommended for dull complexions with an irregular texture. The skin becomes smooth and silky, radiance is restored and pores are tightened. The glycolic acid removes impurities and dead cells from the skin while allantoin soothes and repairs. This combination of active ingredients gently stimulates cell renewal. 5% Glycolic acid solution One of the alpha hydroxy acids (often called fruit acids ), this very small molecule easily penetrates the skin and its acidic ph accelerates exfoliation by destroying the links that bind dead cells together. Allantoin Renowned for its moisturizing, soothing and anti-irritant properties, allantoin is a keratolytic agent that stimulates cell proliferation and the formation of healthy tissue. 50ml

4 purify Foamer 15 exfoliating foam Mask 15 OIL REDUCING MASK Expert Cleanser Removes impurities and dead cells, and purifies the skin. Foamer 15 is recommended for dull complexion, irregular texture and skin imperfections. Astringent Clay Mask Removes dead cells and excess sebum, and purifies combination and oily skin. Mask 15 is recommended for oily skin, and skin that is prone to acne. Prepares skin for cosmetic treatments, and makes the skin smooth and silky. Restores radiance and tightens pores. The skin is purified, a matte appearance is restored, and pores are tightened. Expert, double-action formula. Glycolic acid removes impurities, and permeates the hydroscopic film, while the enoxolone complex soothes the skin. Glycolic acid 15% One of the alpha hydroxy acids (often called fruit acids ), this very small molecule easily penetrates the skin and its acidic ph accelerates exfoliation by destroying the links that bind dead cells together. Enoxolone Renowned for its soothing and calming properties, enoxolone is an anti-inflammatory agent extracted from liquorice root. 100ml The unique combination of smectic clay and glycolic acid purifies and removes imperfections from the skin, tightens pores and reduces excess sebum. Glycolic acid 15% One of the alpha hydroxy acids (often called fruit acids ), this very small molecule easily penetrates the skin and its acidic ph accelerates exfoliation by destroying the links that bind dead cells together. Bentonite Highly absorbent clay that is saturated in fat, which enables it to remove toxins and impurities from tissue. Salicylic acid Causes a keratolytic action that reduces intercorneocyte cohesion, and destroys lipids that bind the outer cells of the epidermis. 50ml Paraben, preservative and fragrance free

5 stimulate Light Ceutic Skin Toning Night Cream Skin Toning Night Cream Stimulates skin radiance and evens out the complexion. Light Ceutic is recommended for dull skin and irregular complexion. The complexion is harmonized and the skin's radiance is restored. 100% of patients enjoyed using and would like to purchase Light Ceutic * The combination of glycolic acid, phytic acid and vitamin C gently exfoliates the skin and regulates the production of melanin, which causes pigment spots. 8% Glycolic acid solution Reduces corneocyte cohesion of the keratin layer of the skin, which enables homogeneous exfoliation. 4% Phytic acid solution Lightening and antioxidant agent. When associated with glycolic acid, phytic acid helps reduce the epidermal pigmentation process by blocking iron and copper ions involved in the formation of melanin. Stabilized vitamin C Considerably improves the skin's resistance to attacks from free radicals. The vitamin C used in this formulation is stable, and will not oxidize. 40ml *In vivo study for the efficacy of Dermaceutic peels on 63 caucasian, asian and dark skin women. Inovapotek. European independent clinical research organisation. July 2013.

6 stimulate Turn Over Stimulating Night Cream Rejuvenating Cream Promotes skin turnover and reduces the appearance of signs of aging. Turn Over is recommended to treat loss of skin tone, wrinkles and fine lines. 85% of patients trust the cream s efficacy and performance * The skin is smoother and appears rejuvenated. The formula of concentrated glycolic acid removes dead cells that build up on the skin s surface and stimulates cellular renewal. 15% Glycolic acid solution Reduces corneocyte cohesion of the keratin layer of the skin, enabling homogeneous exfoliation of upper layers. By removing dead cells from the skins surface, the signs of aging are less visible, the skin appears smoother, and complexion is more homogeneous. 40ml *In vivo study for the efficacy of Dermaceutic peels on 63 caucasian, asian and dark skin women. Inovapotek. European independent clinical research organisation. July 2013.

7 restore Hyal Ceutic Intense MOISTURIZER Long lasting hydration Intense 24hr Moisturizing Cream Helps moisturize the skin after aesthetic procedures. Hyal Ceutic provides essential nutrients to keep the skin hydrated all day. This formula is intensely moisturizing, and helps prevent the signs of premature aging of the skin. This exclusive formula has a smoothing and repairing action while combating changes in the skin, thanks to a highly concentrated combination of low and high moleculars. 5.5% Hyaluronic acid solution This formulation combines hyaluronic acid of low and high molecular weight. The low molecular weight penetrates skin deeply to ensure suppleness and firmness, and moisturizes the skin. The high molecular weight has a protective and hygroscopic role on the skin s surface. 10% Aloe vera extract: Re-moisturizes and regenerates cells. Aloe vera soothes the skin, reduces inflammation, and stimulates production of collagen to combat skin aging. Jojoba oil Creates a non-oily moisturizing layer on the skin surface, relieves sensitive epidermises, and protects the skin from UV rays. Vitamin E Renowned for its antioxidant properties, vitamin E also combats the signs of photoaging. 40ml

8 Regen Ceutic Skin Recovery Cream restore Long lasting hydration Suited for sensitive skin 100% of the patients feel that their skin is well hydrated, firmer and rejuvenated * Repairing Cream Accelerates epidermal restoration post aesthetic treatments: nourishes and firms the skin. Regen Ceutic is recommended for sensitive, dehydrated and aging skin. The highly active formula boosts the skin s recovery and provides optimal moisturizing, soothing, firming and superior skin comfort. The synergy of 2 high-performance repairing peptides stimulates dermal synthesis; hyaluronic acid and powerful antioxidants hydrate and help the skin to protect and restore itself. 3% Peptides Complex: A synergy of 2 of the most efficient peptides, which stimulates collagen, hyaluronic acid and elastin production to induce an antiwrinkle effect from within. 3% Hyaluronic Acid Gel Moisturizes skin and improves firmness. Stabilized vitamin C & E Combination of vitamins which combats and limits the signs of photo-aging and has an anti-inflammatory action. Shea butter Hydrates and nourishes the skin. 40ml * In vivo study of Regen Ceutic efficacy on 21 women for 1 month. Inovapotek. European independent clinical research organisation. July 2013.

9 Restore K Ceutic Post-Treatment cream 84% of patients feel that it is a high performance cream * Recovery Cream Helps nourish the skin following aesthetic treatments, by soothing the skin and delivering essential nutrients. K Ceutic helps reduce skin redness, irritations and inflammations. This advanced formula helps skin maintain optimal moisture, which optimizes the recovery time. This cream contains a combination of ingredients designed to repair, moisturize, protect, and soothe the skin. It also provides complete sun protection (SPF 50 - UVA/UVB barriers). K Complex Features soothing agents essential to combat inflammation. Glycoprotein Favours the development of keratinocytes and the cohesion of fibroblasts while regenerating the skin. Vitamins C and E With renowned antioxidant properties, this combination of vitamins combats the signs of photoaging and limits their appearance. Hypoallergenic and tested under dermatological control. 30ml *In vivo study for the efficacy of Dermaceutic peels on 63 caucasian, asian and dark skin women. Inovapotek. European independent clinical research organisation. July 2013.

10 protect Sun Ceutic 50 ANTI-AGING SUN PROTECTION Anti-Aging Sun Cream Provides high protection for skin exposed to UV rays and helps to prevent premature aging of skin. The skin is restored, and protected from photoaging: spots, fine lines, dehydration. 88% of patients trust the product performance and would like to purchase Sun Ceutic 50 *In vivo study for the efficacy of Dermaceutic peels on 63 caucasian, asian and dark skin women. Inovapotek. European independent clinical research organisation. July Powerful UVA/UVB filters with SPF 50 protect the skin. The dispersed micro-mineral filters allow the cream to be completely transparent, while maintaining efficacy. This unique formula also contains a powerful stem cell stimulator and repairing active ingredients. Zinc oxide and Titanium dioxide These mineral filters form a stable physical barrier against UVB and UVA rays. Hyaluronic acid Creates suppleness and firmness, and moisturizes the skin. A genuine molecular sponge, hyaluronic acid has the power to retain up to four-hundred times its weight in water. Aloe vera Soothes the skin, reduces inflammation, and stimulates the production of collagen to combat skin aging. 50ml

11 prevent C25 Cream Antioxidant Concentrate Antioxidant Day Cream Concentrated in antioxidants which contribute to prevent damage from free radicals. C25 Cream is recommended for irregular complexion and loss of radiance. Complexion is harmonized and glows with natural radiance. 80% of the patients trust the cream s efficacy and performance * This concentrated formula contains 25% stabilised vitamin C, vitamins A, B5, and E, and polyphenols to combat oxidative stress, and protects the skin from premature aging. 25% Stabilized vitamin C A powerful antioxidant, it reduces the signs of skin aging. Vitamin A Improves the structure of the skin and combats the signs of aging, such as wrinkles, fine lines, uneven skin texture, and hyperpigmentation. Vitamin B5 Reduces water loss and keeps the skin smooth and elastic due to its moisturizing properties. Vitamin E Renowned for its antioxidant properties, vitamin E also combats the signs of photoaging. Polyphenols Naturally present in plants and fruit, polyphenols combat the action of free radicals and preserve the integrity of the skin s collagen. 30ml Paraben free *In vivo study for the efficacy of Dermaceutic peels on 63 caucasian, asian and dark skin women. Inovapotek. European independent clinical research organisation. July 2013.

12 TARGET Yellow Cream DARK SPOT CONCENTRATE Expert Skin Toning Cream Stimulates and promotes skin radiance and harmonizes complexion. Yellow Cream reduces dark spots and uneven skin tone. Pigmentation spots are less visible and overall complexion is harmonized. The synergy of glycolic acid, salicylic acid, and highly concentrated pigment-reducing ingredients (20% of active ingredients) exfoliates the skin and regulates the production of melanin, which causes pigment spots. Kojic acid Because it inhibits the production of melanin, kojic acid is a proven, effective treatment of melasma (for exemple the mask of pregnancy). Arbutin Inhibits cells production of melanin (melanogenesis) by blocking the action of tyrosinase. It is also an antioxidant. Liquorice A proven depigmenting agent, due to its flavonoid-rich composition. Liquorice inhibits the action of two tyrosinases, which catalyse the production of melanin. It also has soothing properties. Morus alba A species of fruit tree, morus alba limits the production of melanin by inhibiting the action of the tyrosinase. It is also an antioxidant. Glycolic acid Speeds up exfoliation and promotes cell renewal. Salicylic acid Causes a keratolytic action that reduces intercorneocyte cohesion, and destroys lipids that bind the outer cells of the epidermis. 15ml

13 TARGET Spot Cream Depigmenting Cream 83% of patients believe in the product s efficacy compared to other products used in the past * Post Spot Peel Treatment Reduces pigment spots and promotes homogenous complexion. Spot Cream is to be used as part of the Spot Peel Treatment protocol, to treat pigment spots and melasma. Helps reduce the appearance of pigment spots and decreases melanin content. Mandelic acid Is known to diminish the appearance of fine lines by acting as a humectant and its exfoliating action breaks the bond between dead skin cells. Idebenone Is found to possess anti-aging properties and protect against damage by free radicals. Emblica Protects the skin from harmful photo-damage thanks to its controlling effect on oxidative processes. Retinol Stimulates collagen production and prevents its degradation. Acts on the skin cell s renewal process to provide a luminous and healthy complexion. Salicylic acid Causes a keratolytic action that reduces intercorneocyte cohesion, and destroys lipids that bind the outer cells of the epidermis. 30ml Paraben free *In vivo study for the efficacy of Dermaceutic peels on 63 caucasian, asian and dark skin women. Inovapotek. European independent clinical research organisation. July 2013.

14 clinical research PROVEN S In 2013, Dermaceutic carried out the most extensive clinical research in the industry Methodology Half the volunteers used Dermaceutic cosmeceuticals in combination with their professional treatments. Cosmeceuticals proven efficacy as peel treatments enhancer Skin color homogeneity improvement Smoothing of skin s texture Anti-wrinkle effect Reductin in volume of frown lines Less desquamation following peel treatment Light Ceutic 100% enjoyed using Light Ceutic, trusted its efficacy and performance and will keep using Light Ceutic after the treatment Turn Over 85% of patients trust the product s efficacy and performance and believe that it is a technical product K Ceutic 84% of patients feel that it is a high performance product 93% find the texture pleasant 81% are interested in continuing to use K Ceutic after the peel program Sun Ceutic 90% of patients are confident this product works 88% are interested in continuing to use the cream 94% like its texture and spreadibilty C25 Cream Over 80% of the patients trust the product s efficacy and performance 80% are interested in continuing to use C25 Cream 100% find the texture pleasant Spot Cream 83% of patients believe it has a higher efficacy than other products used in the past 83% trust its efficacy and performance 100% like its fragrance and spreadibility Regen Ceutic Up to 109% increase in skin hydration +32% increase in skin firmness +43% decrease in wrinkles volume 100% feel that their skin is well hydrated, firmer and rejuvenated 95% feel that their skin is lifted and regenerated 100% would like to purchase Regen Ceutic Day 0 Day 28 Reduced appearance of wrinkles, bags, darkness and puffiness under eyes Increased skin radiance and clarity Firmer skin, less wrinkle volume In vivo study for the efficacy evaluation of Dermaceutic professional peels and homecare products on 63 Caucasian, Asian and dark skin women. Inovapotek. European independent clinical research organisation. July In Vivo Study of Regen Ceutic Efficacy on 21 Women for 1 month Inovapotek. European independent clinical research organisation. July 2013.

15 For any further information you may require about the Dermaceutic range, please visit: 11/2013

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