Beauty through Innovation Sensory INNOVATOR

Transcription

1 EYESEL Beauty through Innovation Sensory INNOVATOR

2 EYESEL Crossing view and Integrated values Business Category BT DIGILOGUE IT Natural Raw Materials Cosmetics, Food, and Medical supplies Biomass (BMR) Eco-friendly Materials Global Fair Trade Raw Materials Cosmetic Bio chip Photo Sensitive Materials Medical Filler Device Preservative Vessel New Concept Beauty Device Life Medical Equipment Ubiquitous Cosmetic Cultural Life

3 EYESEL Vision R&D Company with Global Network R&D Network Business Network 2020 year s Global Top Bio R&D Firm Bioconversions Business Bio Beauty Device for Ubiquitous Life Medical Device for Skin Diagnosis Biotechnology and Bioengineering map Business System Natural Resources R&D Center More Natural source secure : Plant Stem Cell, Plant DNA Global Natural Source Map Secure Cooperation application of Raw materials in Cosmetic, Food, and Drug New Natural Concept & Mechanism for Cosmetic

4 Company and CEO History Company History Company EYESEL Co., Ltd. CEO Beom-Jun, Kim Registration of incorporation Company s Address Homepage #911~913 U-Tower, Yeongdeok-dong, Yongin-si, Gyeonggi-do, Korea CEO History Coreana Cosmetics R&D Center Senior Researcher SK Chemical R&D Center Senior Researcher Ellead Clinical Center Chief manager Interlees Nano R&D Center R&D Director Interlees Co., Ltd. Sales director Now Eyesel Co., Ltd. CEO Now Ajou University Biotechnology Adjunct Professor Registrated Patents 62 items

5 Developmental Process ~ Now Incorporation ( Interlees Joint Venture) Amorepacific HERA Dermasonic and IOPE Dermalay Development Stem Cell Cosmetic Formula development (PROSTEMICS, PARMICELL) ELMIZMOR(ion Beauty Device) Russia Export MELA X Dermaion GS Homeshopping Acquired Plant Stem Cell Callus)Culture Technology(Patent Registration) Korean Government Certificated Venture Company( ) Korean Small and Medium Business Administration Supported Project ( ) Korean Government Certificated R&D Institute Foundation( ) Pulmuone ISSINE Development Amway W-Care Development SPF Boosting Polymer Development Plant Placenta Development Skin Cell Membrane like Vesicle composition Development Bio-conversion technology Development with Mushroom s mycelium culture Phyto-hyaluronic acid Development Japan DHC Beauty Device Development with New technology or Function MPS Dr. SYS Shopping Mall Open MAXCLINIC Foam Cleansing Oil Formular Development (Home shopping launching) Developing of Anti-bacterial Cosmetic Container Developing of Natural Sun Filter Developing of Skin Temperature Response Polymer Developing of Natural Preservative with Nano technology Developing of Cosmetic New Function Formula MAXCLINIC Foam Cleansing Oil : More than 50 millions sale Medical Cosmetics Development ( Stem cell, Botox, PDRN, Acne, Atopy, Rejuvenation, Hair growth Bust Up, Anti-wrinkle, Whitening, Slimming etc. ) IoT Based Beauty Device Developing

6 OUR DIFFERENCY Emotional science

7 EYESEL Developed Stem Cell Cosmetic Brands -. PARMICELL - Beaucell -. EYESEL Dr. SYS(own brand) -. STARS - CARECELL -. HUMEDIX HUON HYPERCELL -. MICELLFLONIA - MICELL -. MOTIVEBIZ HONEY CELL -. FOX & PLANET - YOUNGCELLOGY -. FOX & PLANET CELL IN CELL

8 EYESEL Brand - Dr.SYS Brand Concept Home Aesthetic Dr. SYS is a home aesthetic cosmetic brand containing various kinds of plant stem cells such as wild mountain ginseng, green tea, bamboo and home aesthetic device treatment using ion, ultrasound, far infrared ray, LED, and vibration. Dr. SYS's Home Esthetics program is a functional cosmetic product containing plant stem cells and growth factors with excellent ability to differentiate and regenerate. Dr. SYS can help your beauty using developed skin treatment program such as Iontophoresis, Sonophoresis, and Photo dynamic treatment (PDT), which are u sed in dermatology and esthetic shop to maximize the efficacy.

9 Dr.SYS Brand Concept Home Aesthetic

10 Dr.SYS Brand Concept Home Aesthetic Plant stem cells, which maintain their vitality and keep growing, activate skin cells and stimulate regeneration, making them clear and transparent skin. There is no destruction of the active ingredient by extracting stem cells by cold pressing. It has strong differentiation and regenerative capacity like human stem cells. There are no ethical or safety issues like human stem cells. Skin cell membrane mimic system stabilizes active ingredient by forming nano size membrane. In addition, the penetration efficiency of the skin is increased, and after the penetration of the skin, the active ingredient moves out of the cell due to the osmotic pressure and is released slowly, so that the effect can be maintained for a long time.

11 Dr.SYS Brand Concept Home Aesthetic Give vitality to the skin. Beauty Device EYESEL Beauty Device is a home aesthetic beauty device that provides comfortable and economically beautiful skin at home instead of an esthetic shop and a dermatologist who have to pay for expensive expenses. EYESEL Beauty Device is a beauty device which applied ion and ultrasonic massage principle used in dermatology and aesthetic shop and it has programmed ion, vibration, ultrasonic, far infrared ray function, and it increases skin absorption of active ingredient more than 30 times. No matter how good the skin is absorbed into the skin, it is useless. Experience incredible skin changes with Dr. Sees beauty equipment. Increases skin absorption of active ingredients 30 times or more. Dr. SYS Iontophoresis and Sonophoresis technology maximize skin penetration of active ingredients

12 EYESEL Developed Stem Cell Brands MICELL 6.8 x 10 8 Adipocyte Stem Cell Media Liposome 36.5% More than 40 active ingredients

13 EYESEL Developed Stem Cell Brands PHARMICELL Beaucell

14 EYESEL Developed Stem Cell Brands HU:ON HYPERCELL Activator Ampoule

15 EYESEL Developed Stem Cell Brands RETEENAGE Extra Gold Stem Ampoule : Clinic Skincare Method

16 EYESEL Developed Stem Cell Brands YOUNGCELLOGY

17 EYESEL Developed Plastic Surgery Filler Brands CELLIANCE PDRN & HA

18 EYESEL Developed Plastic Surgery Filler Brands BRAND NEW BNMS Meso Ampoule & MGF Rejuvenating Ampoule PDRN & HA

19 EYESEL Developed Plastic Surgery Filler Brands Suhada PDRN & HA & BTX(Botox) Peptide

20 EYESEL Developed Plastic Surgery Filler Brands MTS PDRN & HA & BTX(Botox) Peptide

21 EYESEL Developed Plastic Surgery Filler Brands Botox Ampoule RELAXSIM BOTOX (Botulinum toxin) is a kind of neurotoxin produced by Clostridium botulinum. It acts on the endogenous nerve endings of the neuron junctions of mammals to inhibit the extracellular release of synaptic vesicles. This poison does not affect the synthesis or storage of the transducer and the conduction of action potentials. It consists of a heavy chain of 100 kda and a light chain of 50 kda, folded into one S-S bond. The heavy chain is necessary because the toxin specifically binds to the neuronal membrane and the light chain enters the cell. In the cell, the reduced light chain after bisecting by proteolytic enzyme acts as a peptide internal hydroliase with Zn2 +

22 EYESEL Developed Plastic Surgery Filler Brands BTX(Botox) Ampoule RELAXSIM BOTOX (Botulinum toxin) Botox has been spread in the European market, and now, as a raw material for wrinkle improvement worldwide, many products have been commercialized. What is BOTOX? Botox inhibits the secretion of acetylcholine which is a neurotransmitter secreted from nerve cells and suppresses the contraction action of muscle Acetylcholine is secreted from nerve cells when facial expressions are formed, and secreted acetylcholine binds to the SNARE Complex (VAMP, Syntaxin, SNAP-25) to be released outside the nerve cells. The released acetylcholine binds to the receptors of muscle cells and transmits signals, which contract muscles to form facial wrinkles. Botox destroys SNAP-25, the main protein in the SNARE complex, and ultimately interferes with the formation of the SNARE complex, thus preventing the release of acetylcholine to the outside and suppressing facial wrinkles.

23 EYESEL Developed Plastic Surgery Filler Brands BTX(Botox) Ampoule RELAXSIM Botox like mechanism peptide Product Name INCI Name Explanation Argireline Leuphasyl Syn-AKE Acetyl Hexapeptide-8 Pentapeptide-3 Tripeptide With concept ingredient that is most similar to Botox Prevent wrinkle formation by competitive binding with SNAP-25 which is a major constituent protein of SNARE complex. Reduces the concentration of Ca ions necessary for the release of neurotransmitter acetylcholine and prevents the release of acetylcholine. The released acetylcholine competitively binds to receptors for binding to muscle cells.

24 EYESEL Developed Plastic Surgery Filler Brands BTX(Botox) Ampoule RELAXSIM Argireline Similar like BOTOX mechanism. Argireline, which mimics the N-terminal of the SNAP-25, is a peptide with 6 amino acids that competitively react with SNAP-25 to form the SNARE complex. This unstable SNARE complex formed by Argireline eventually fails to release the vesicles containing neurotransmitters to the outside, reducing wrinkles. Compared to Botox, it is safe, has good skin-affinity, and has a long lasting effect.

25 EYESEL Developed Plastic Surgery Filler Brands BTX(Botox) Ampoule RELAXSIM Our Botox like peptide BTXEL It is the most similar peptide to BOTOX and has a similar function as a mechanism. It competitively reacts with SNAP-25 as a peptide of 42 amino acids mimicking the active site of SNAP-25 to form SNARE complex. This unstable SNARE complex by BTXEL eventually reduces wrinkles as it does not release vesicles containing neurotransmitters to the outside. Compared to Botox, it is safe, has good skin-affinity, and has a long lasting effect.

26 EYESEL Developed Plastic Surgery Filler Brands BTX Ampoule RELAXSIM Our Botox like Ampoule RELAXSIM Also known as " Spread Botox" ampoule, it is easily penetrated into the skin, effective in increasing skin elasticity and anti-wrinkle. It contains 25ppm of BTX like peptide, and if you apply it to the skin where you want to see the Botox like effect. You feel like you are injecting Botox immediately. Main Ingredient Oligopeptide-27(BTXEL), Niacinamide, Adenosine, Sodium DNA(PDRN), Sodium Hyaluronate, EGF, IGF-1, bfgf, KGF, Palmitoyl Tripeptide-5, TGF-beta

27 EYESEL Developed Plastic Surgery Filler Brands PDRN Ampoule PDRN is a tissue regeneration agent that exists in vivo, which promotes regeneration of the skin cells. They are usually harvested from the testes of the salmon, and they are made of refined water. PDRN is composed of a DNA composition that is composed of DNA, which is composed of salmon DNA, and has a variety of skin improvements, which makes it a great ingredient for a variety of skin treatments. PDRN has an excellent effect on organizational regeneration. When PDRN is combined with cell receptors in the body, it creates microscopic blood vessels in the damaged area, recovers the tissue in the stem cells, produces collagen in stem cells, and promotes regeneration of skin cells. Why is salmon DNA? The salmon is a biologically rich organism, especially the composition of the base material, which is composed of people who make the most of salmon DNA, which can be added to the human body and can be used without worrying about safety when administered in the human body.

28 EYESEL Developed Plastic Surgery Filler Brands PDRN Ampoule The biggest effect of PDRN is tissue regeneration. It helps heal the rapid recovery of damage or scarring, which relieves swelling, flushing, and pain.it is currently being used as an organization for tissue and pain clinics in hospitals and clinics, and is being used for injections of skin tissue in the name of cosmetic surgery and clinics. Enhance skin problems by improving overall skin problems such as skin bleaching, moisture reduction, reduction of pores, improvement of skin color, and improved skin tone. Fast, prominent regeneration of the skin cell regeneration and cell growth, and the ability to regenerate tissue by reconfiguring the epidermis tissue is long-lasting. Therefore, it is a substance that helps the fundamental regeneration and growth of skin tissue damaged by skin troubles, aging, scars, and ultraviolet rays.

29 EYESEL Developed Plastic Surgery Filler Brands PDRN Ampoule Salmon PDRN, peptide complex, growth factors, collagen, and molecular weight combine to combine the peptide compounds with the optimum mix of sodium to moisturize your skin texture. It is also an ampoule that not only helps skin regenerate from the skin filling it, but also improves wrinkle and skin whitening of the skin. Main Ingredient Niacinamide, Adenosine (Double functional cosmetics) Sodium Hyaluronate, Sodium DNA(PDRN), Palmitoyl Tripeptide-5, EGF, IGF-1, bfgf, KGF, TGF-beta, sh-decapeptide-7, sh-octapeptide-4, sh-oligopeptide-9, sh-pentapeptide-19, Octapeptide-7, Copper Tripeptide-1

30 EYESEL Collaborated Plastic Surgery Hospital Kim Jong Seo Plastic Surgery RETEENAGE Brand Major Field Facial contour, Skin Rejuvenation Brand New Clinic BNMS, Rejuvenating Brand Major Field Korean Get It Beauty TV Program, baby injection, salmon injection Model line Plastic Surgery Major Field Liposuction, facial contouring The Clinic Major Field Anti-aging center anti-aging clinic, molding Face Care

31 EYESEL Beauty through Innovation Sensory INNOVATOR