Fall Special. Buy Five Colostrum Gels and Get One Free. DermaConcepts

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1 Product of the Month: Colustrum Gel Autumn and winter are the ideal times to regenerate and reverse the photo damage sustained during the summer months. With all the hype surrounding ALA-PDT, Peptides and numerous other treatments for skin rejuvenation, it s sometimes hard to know where to start. The answer is quite simple: start at the beginning with the first food of life Colostrum! Protein, immune factors and numerous growth factors in Colostrum provide newborn babies with the essential nutrients needed to begin a healthy life. Immune factors in Colostrum can help balance and support a healthy immune system, which is the key to good health. Growth factors supply the necessary building blocks for the newborn, enhancing the growth of cells, muscles, tissue, bone and cartilage. As we age, our bodies produce less and less of these vital factors, increasing signs of aging, and making it more difficult for us to fight disease. We can utilize these miraculous ingredients to benefit aged and damaged cells in our bodies and skin. Colostrum is the foremilk of breast milk and is produced for the first 72 hours postpartum. Environ uses bovine Colostrum which is nearly identical to human Colostrum but research confirms it is four times richer in immune factors than human Colostrum. IMMUNE FACTORS Medical and clinical studies show immune factors in Colostrum fight viruses, bacteria, yeast, fungus, allergens and other toxins. Immunoglobulins Immunoglobulins provide a superior defense in both treatment and prevention of viral infections, bacterial infections, allergies, fungus and yeast. There are five types of immunoglobulins present in Colostrum, specifically IgA, IgD, IgE, IgG, & IgM. Bovine Colostrum contains mostly IgG with very small amounts of IgA, IgD, IgE, and IgM. Human Colostrum typically contains 2% IgG content, while bovine Colostrum can have from 8% to above 25% IgG content. These are protein molecules that are effective in fighting bacterial and viral infections, parasites, and yeast. Immunoglobulins are energizing elements in Colostrum that are anti-inflammatory in nature. Antibodies Colostrum has been shown to contain specific antibodies to more than 19 specific disease-causing pathogens including: rotavirus, h. pylori, cryptosporidium, salmonella, candida, streptococcus, staphylococcus and E. coli. PRP (Proline-rich Polypeptide) Shown to help regulate the thymus gland (bodies central command for the immune system), PRP can stimulate a weakened immune response as well as balance an over-active one. Lactoferrin An iron-binding protein with antiviral, antibacterial, anti-inflammatory properties, Fall Special Buy Five Colostrum Gels and Get One Free. Mature skin becomes noticeably thinner. This is particularly evident in a woman who either is going through or has gone through menopause as well as middle aged men who spend considerable time outdoors. Thinning skin also accompanies severe sun damage. To assist with this problem, Environ s intensive Colostrum Gel has been formulated to address this skin condition. It is nature s perfect combination of immune factors, growth factors, vitamins and minerals. Colostrum Gel is designed to soothe, refine and tighten skin. It assists in the reduction of fine lines and helps to promote healthy collagen and elastin. Colostrum also is wonderful to use on skin that has lost its sheen and for those who smoke, as it restores a natural, healthy luster to one s skin. Remember to always apply a sunscreen. Promotion expires Dec. 1, Lactoferrin has been implicated in the treatment of such diseases as cancer, HIV, herpes, candida albicans and other infections. Glycoproteins (protease and trypsin inhibitors) These factors protect the immune and growth factors in Colostrum. Lactalbumins Research indicates tremendous possibilities that Lactalbumins can be highly effective against numerous forms of cancer and viruses. Continued on reverse.

2 Product of the Month continued from front. Cytokines (Interleukin 1 & 6, Interferon Y & Lymphokines) These chemicals are involved in cell-to-cell communication, antiviral and anti-tumor activity and regulation and intensity of immune responses. Cytokines help increase T-cell activity and stimulate production of immunoglobulins. One cytokine, Interleukin- 10, is a potent anti-inflammatory agent that has been shown to have a profound effect on pain relief. Interleukins have shown particular promise in fighting cancer. Lysozymes Helps protect the body from bacterial infections. Lysozyme has actually been shown to destroy bacteria on contact and is an effective topical antibiotic. GROWTH FACTORS Medical studies have shown that the vital growth factors from bovine Colostrum are practically identical to human Colostrum in composition. Furthermore, it has been shown that growth factors stimulate normal growth, as well as help regenerate and accelerate the repair of aged or injured muscle, skin collagen, bone, and cartilage and nerve tissues. Growth factors also stimulate the body to burn fat for fuel instead of the body s own muscle tissue in times of fasting (diet), and build lean muscle. In addition, growth factors can be used as an effective topical application for burns, injuries and skin rejuvenation. Epithelial Growth Factor (EGF) EGF is instrumental in protecting and maintaining the skin. Along with the other growth factors in Colostrum, EGF can stimulate normal skin growth and repair cellular tissue. Insulin-like Growth Factor I and II (IGF-I & IGF-II) IGF I & II are the most abundant growth factors in Colostrum. They affect how the body uses fat, protein and sugar. IGF-I is one of the only substances known to stimulate the repair and growth of DNA and RNA, making it one of the most powerful antiaging substances. IGF-I have been clinically proven to help increase lean muscle mass and may help regulate blood sugar and cholesterol levels. Transforming Growth Factors A & B (TGF A & B) TGF stimulates the proliferation of cells in connective tissue and assists in the formation of bone and cartilage. It is also showing promise as a therapeutic agent in bone and wound healing. TGF can help repair tissue and may support the development of growth of the lining of the gut. Platelet-Derived Growth Factor (PDGF) PDGF has been shown to help with cell division in connective tissue, smooth muscle, and fibroblasts. It may also assist in neuron survival and regeneration. Colostrum is an ideal treatment for any skin needing improvement in immunity and growth. a) Peri and post-menopausal skin. As people pass their 40 s, their hormone levels drop and they have lower concentrations of growth factors in their organs. Fortunately growth factors are not species specific and so we can employ the growth factors normally found in Colostrum to stimulate the growth of the epidermis and the dermis. b) Acneic and problematic skin. The cells here require more immunity to bacteria and also repair of already damaged cells. c) Indicated for older, chrono-aged as well as sun damaged skin and those with fine lines. Also important for those who have thin skins and wish to thicken their skin and build up collagen. d) Burn wounds. All humans are exposed to pollution, toxins, carcinogens, etc. They are in the air we breathe and the food we eat. When our bodies are healthy, our immune system fights off these pathogens without needing any help. However, if our immune system is compromised in any way (which is unfortunately true for most of us) Colostrum can help restore the body and skin s ability to function normally. Environ Client Survey The results are in from our client satisfaction survey! Thanks for taking the time to complete the survey and for the overwhelming endorsement of our staff, business practices and product line. Our average score in all categories ranged from out of a possible score of 5. Overall results of the survey applauded customer service and office support, product quality and efficacy and training and education programs. You collectively asked for more advanced training courses and an increase in available promotional materials. We plan to act on these suggestions in very short order. There will be new brochures, promotional, point of sales displays and increased advanced training all within the coming months! Upcoming Training Training and refresher courses: Boston, MA Sept. 18 and 19 Bethesda, MD Oct. 2 and 3 Cincinnati, OH Oct. 14 and 15 Boston, MA Nov. 6 and 7 (Products) Boston, MA Nov. 21 (Peel Training) If you would like a training course scheduled for your area this fall, please contact your rep, or our home office at , so we may develop a schedule to best meet your needs.

3 Environ Annual Meeting We just returned from an exciting 10 days in South Africa. Our trip was comprised of an advanced course in skin science, an update on all the new and exciting products that will be launched shortly, as well as cutting edge research that will lead to new products in the coming months, and a master class in training techniques. Environ only releases new or improved products when they are measurably better than existing products on the market and can make a real difference in skin conditions. NEW BROCHURES A new brochure designed for your clients and patients explaining the Environ system is going to be released in the next month. Available in reasonable quantities at no charge, this informative and attractive publication is a great way to introduce Environ to your practice, makes a wonderful addition to your waiting area, and answers many frequently asked questions about skin care and Environ. An improved DF Ionzyme Machine pamphlet is also available. It explains the purpose and function of Pulsed Iontophoresis and Low Frequency Sonophoresis to your clients and includes several sets of before and after photos. POINT OF SALE CUBES This winter there will be a series of point of sale display cubes with wonderful graphics for each Environ Range. These can be used on counter tops, case displays or as wall or mobile decorations. We expect to have these available prior to the holiday season. There is no charge for cubes on orders over $1,000. NEW PRODUCTS The Environ Research and Development team has been hard at work continuing to ensure Environ is one step ahead in the skin care industry. New, state-of-the-art products are on the horizon. It is anticipated that over the coming 18 months, 14 new or improved products will be released. Sebumask is set to be released in late October. Details on this kaolin based product include active ingredients of tea tree oil, vitamin E and salicylic acid. One would use it as one uses Claytech Masque but for problematic and acneic skin. Improved Serum C-Quel, now in 10 ml bottles, is presently available. Added active ingredients include a more effective Vitamin C for ionization, and Retinol to replace Retinyl Acetate. The price remains the same for the 10 ml size as was for the 5 ml. C-Quence 4 is also being released in October. Please remember, this is a very, very potent product and should only be given to clients who are currently using C-Quence 3 and Retinol 2. If they move up too soon to this highly effective product, a temporary retinoid reaction will result. Not everyone can or should move up to C-Quence 4. In the future, expect to see an entire new concept in treating pigmentation. The results are extraordinary. This new generation product is more effective and brings to the market new, safe ingredients and technology. While testing is ongoing and Des and his R & D team will only release a product when they are completely satisfied it is the best on the market, we were bowled over with what we saw and heard. The future of high tech skin care is exciting. A Self Tanner and efficacious and luxurious Body Treatments are on the horizon, as are additions to the ground breaking Ionzyme Range of anti-aging products. Dr. Des has also put together a home cool peeling kit to compliment the professional, in-office, strength peels. This will allow your patients the opportunities to self administer a series of light peels as a follow up maintenance program until the next professional treatment. These are particularly effective in treating some forms of acne, light pigmentation and to reduce the signs of photo-aging. Environ Receives Multiple Awards Named Outstanding Company and Exporter of the Year Once again, our parent company, Environ South Africa, has received accolades for its business, humanitarian and personnel practices. The company has been named one of the outstanding companies in South Africa as well as receiving the award Exporter of the Year from the government. Environ offers medical care, educational scholarships, Tuberculosis and HIV screening, health and personal counseling, and hires individuals with disabilities. The company has been lauded for its employment practices. The company also received plaudits for its handling of environmental matters including its use of water, management of effluent, recycling, and e-mark certification. The factory, research and development staff now totals 120. Our state-of-the-art factory has been recently expanded to ensure we can meet present and future needs for years to come. Environ is one of a very few companies that owns and manages its own factory, production facilities and dedicated research staff all ensuring we remain a state-of-theart company.

4 A Total Program of Care for Age Management by Alexandra J. Zani A growing trend in medical practices is the expansion into ancillary services. Rising operational costs of a medical business have forced physicians to take a look at how they can expand and better serve their patients. Moreover it also will supplement the requirements of an aging populace who are not about to settle for a rocking chair. The boomers are being forced to work way beyond what was considered years ago as a normal retirement age. The medical spa and/or anti-aging skin care center concept is here to stay. Costs of expansion are great and require exhaustive architectural and financial planning. There are many details to consider. A very important one is the choice of products and services. Retailing is not to be looked upon lightly since it can bring in 35-45% of total revenue. Product consideration is vital to providing your patients/ customers with good results. Product choice is tantamount to the machines and procedures taken into consideration for skin treatments. Selection of products is at best foreign to those who are delving into a medical esthetics or anti-aging spa venture for the first time. When visiting a potential Environ client, I may discover that there is a plethora of unrelated products on a retail shelf. An over abundance of inventory potentially leads to confusion both to staff and customer as well as revenue loss. Perhaps the products no longer serve your clients needs. Remember, Environ will buy out your inventory of no longer wanted products. Certain conditions apply. Call the office at or your sales rep for details. What is your treatment focus? Some offices offer hair removal and/or IPL only. Certainly it will bring in customers. However, these modalities alone will not address a total system of care and correction that speaks to aging skin, pigmentation, acne, and other skin challenges. Combining numerous modalities IPL, laser, ultrasound, iontophoresis, and targeted corrective facials that includes a scheme of graduated peels with a home regimen of vitamin therapy will produce RESULTS and repeat business. Does your current product line allow flexibility when you re purchasing? Is there a minimum order requirement? Perhaps your current products are not performing as you initially expected. Wouldn t it be great to be able to participate in a buy-back program so that you can begin a better program that gives credit towards your old products? Is your present company focused on building a partnership with you? Does the company provide continuing education? You can have the best products and treatments; however, results ultimately depend on the expertise and precision of the practitioner. Does the company own its own manufacturing? Does it follow guidelines for using the latest scientific research for developing efficacious formulas? Are products obtainable through the Internet? Skin conditions need a thorough analysis by a skin care professional who can prescribe the correct treatment system and companion home care. Self-prescribing through the Internet is not recommended. You ve made a great investment in your business, including product sales. Ms. Zani is the Environ sales representative for North and South Carolina More so, there may be less understanding of how significant the process of combining in-clinic facial treatments for skin rejuvenation and/or pre- and post-surgery needs lead to a total system of care that exudes maximum results and success for your patient/client. Is your choice of products and treatments actually going to serve the needs of your patients/clients? Many product combinations and aggressive treatments may produce more damage to an already compromised skin. A better choice would be to provide gradual correction in order to support the skin s own healing mechanisms. Follow this by a simple home regimen that works in tandem with your clinic treatments. Choose a product line that allows for greater flexibility for moving to higher levels of nutrients and treatments. Approximately 90% of the success of a skin management program relies on compliancy to a home care regimen. Grandma, didn t anyone tell you about RAD sunscreen?

5 Alpha Hydroxy Acids: Question & Answer By Dr. Ernst Eiselen, Medical Advisor Q: I am interested in your products but rather nervous about using AHA s that are used in your toning lotion which I presume you use twice a day. During the 1990s there was a lot of scare stories about these ingredients and some say that eventually they will cause more sun damage to the skin. Please, can you tell me a bit more about the AHA s used in the Environ products, where they are derived from, etc? Also, are the vitamins (A, C and E) derived from natural products? A: Thank you for your interesting questions as they raise some pertinent points. You need not be scared of the AHA s. They are present in suitably low dosages and at a friendly ph in the Environ products. They serve as penetrant enhancers for the vitamin enriched Environ products. I would suggest using toners only once per day initially until your skin is well adapted to the vitamin A. Many of the scare-stories pertaining to cosmetic ingredients came from people who either used the acids in high concentrations, or as single ingredients without any added vitamins and anti-oxidants. Some of the bad publicity was just simply hoax-like reports from people who took data out of context. The skin requires treatment with formulations which are well-balanced to contain many different elements at the right concentrations and correct formulations. The phrase natural products is one which appears to have deepened the confusion about ethical and good chemistry. Natural is a word which appears to have taken on the meanings of organic and safe. I suspect that the manufacturers of botanical and other extracts have used this word to denote and foster these concepts in the minds of the buying public. A critical appraisal of the concept unfortunately lays the confusion bare. There can be nothing more natural than a molecule synthesized in a laboratory with the exact structure of the one found in nature. The extract from a plant or chemical source will be termed natural yet could contain unwanted or even potentially harmful substances not removed by the extraction method. In fact some of the most poisonous substances like botulinum toxin, mercury, arsenic and radioactive materials are all perfectly natural. We should therefore be careful to equate the concept of natural with safe and wholesome. Environ uses only the highest quality raw materials available and many of the ingredients are synthetically prepared to be nature identical. This is a much more reliable, precise and ethical concept. It means that the molecules are exact copies of those active ones found in the cells of living human beings. It makes everything a lot more predictable and is safer than any other approach to the preparation of a cosmetic. The absence of surprise ingredients, as will inevitably be found in many extracts, makes the Environ products certainly much safer and in every way more natural. Environ s formulations are based on properly researched scientific data, tested only on human volunteers and are only released to the public once the quality, efficacy and safety can be assured. Please follow the instructions of your skin care professional closely and remember to take the dosage of vitamin A up very slowly over several months. Do not be in a hurry. Good skin takes time, but the rewards will be lasting. Environ in the News The past several months have seen an exponential increase in press coverage for Environ and its staff in the United States. Articles have been published in several medical journals on medical needling and its effectiveness in treating fine lines, wrinkles and acne scarring. Copies are available upon request. The following publications have praised Environ products in their editorial or new products sections: Skin Inc.; Aesthetic Trends and Technologies; Plastic Surgery Magazine; Lucire; Happi; Fashionista; Fashion Tribes; Plastic Surgery Products; Plastic Surgery.com; PreferredConsumer.com; TheCelebrityCafe.com; Brentwood Magazine; Foam; Beauty News; Woman s Post; and Your Life. Pending placements include Les Nouvelles Aesthetique, Urban Male, Medical Spa Report, Men s Exercise, and many other national magazines that work on a longer lead time.

6 Your presenter: Florence Barrett-Hill is one of the world s foremost CIDESCO & ITEC qualified skin treatment therapy experts with over 30 years of experience and knowledge to share. Florence has a vast knowledge from cosmetic chemistry through to paramedical techniques and is the author of the world famous book Advanced Skin Analysis Over 1000 Aestheticians & skin care technicians have already taken their careers to the next level with Florence s seminars over the past ten years. Join them! BOOK EARLY! Limited Seats Available Distributor of Environ Skin Care present a special event one-day workshop Melanogenesis and the Treatment of Pigmentation Evaluate the different types of pigmentation Review of Melanocyte lifecycle and synergistic cells Establish cause and effect of cells and systems affected. Review the cosmetic chemistry of all actives that are most effective. Explore treatment modalities that are effective on this skin condition. Plan an effective treatment program Join international skin treatment therapy expert Florence Barrett-Hill and embark on a journey of discovery and revision of your chosen career. Expand your potential to offer much more to your clients! One day intensive workshop: $ late registrations on the day: $ Monday, September 26, am to 4.00 pm Continental breakfast and check-in from 8.00 am Venue: Marriott Boston Newton, 2345 Commonwealth Avenue, Newton, MA Ph SEMINAR REGISTRATION Name:...Clinic.. Address Phone.. Fax/mobile.... Paying by: MC / Visa Amex Card No..Exp..... Name on card:.. Post or fax your registration to: DermaConcepts, 766 Falmouth Road, Unit C17 Mashpee, MA Phone: Fax: PALOMAR IPL systems GENTLEWAVES LED Photomodulation Proudly sponsored by: ORION LASER Harmony IPL system MEGAPEEL Microdermabrasion QUADRA 4 IPL system

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