GIVAUDAN LAVIROTTE S.A. 56, rue Paul Cazeneuve BP Lyon FRANCE Tél.: +33 (0) Fax: +33 (0)

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2 SEPICAP PROPERTIES AQUAYL TM TM MP LIPACIDE TM UG LIPACIDE TM CG SEPICALM TM S SEPICALM TM VG SEPITONIC TM M3 *SEPPIC being: Moisturiser and restructurer Multi-protection Purifyers of oily hair Anti dandruff Soothers and dermoprotectors Formulas for fragile hair Hair growthing ECOCERT validation INCI (CTFA) name ylitylglucoside & Anhydroxylitol & ylitol Sodium Cocoyl aminoacids & potassium dimethicone PEG-7 panthenyl phosphate Undecylenoyl glycine Capryloyl glycine Sodium Cocoyl aminoacids & sarcosine & magnesium aspartate & potassium aspartate Sodium Palmitoylproline & nymphaea alba flower extract Glossary ( ): am : Active Matter cp : Commercial Product SLES : Anionic surfactant widely used in foaming formulas (Sodium Lauryl Ether Sulfate) EM : Electronic Microscopy MIC : Minimum Inhibitory Concentration HET-CAM test : Alternative methods to animal testing for irritation evaluation Magnesium aspartate & zinc gluconate & copper gluconate SEPPIC S.A. Tour KUPKA C 7, boulevard Franck Kupka 939 Paris La Défense cedex FRANCE Tél. : 33 () Fax: 33 () GIVAUDAN LAVIROTTE S.A. 5, rue Paul Cazeneuve BP 3 9 Lyon FRANCE Tél.: +33 () Fax: +33 () and, depending on the country: SEPPIC Inc 3, Two Bridges Road, suite 1 Fairfield, New Jersey USA Tél. : (1) Fax : (1) SEPPIC UK Ltd 5 Salisbury Road PO Box 33 - Hounslow TW SH - ENGLAND Tél. : () 577 Fax : () 57 1 SEPPIC ITALIA SRL Via Quarenghi Milano ITALY Tél. : (39) 3911 Fax : (39) 391 Nota The analytical specifications warranted are only those mentioned on the certificate of analysis supplied with each delivery of the product. Except as set forth above, SEPPIC* makes no warranties, whether express, implied or statutory, as to the product which is the subject of this document. Without limiting the generality of the foregoing, SEPPIC* makes no warranty of merchantability of the product or of the fitness of the product for any particular purpose. Buyer assumes all risk and liability resulting from the use or sale of the product, whether singly or in combination with other goods. The information set forth herein is furnished free of charge and is based on technical data that SEPPIC* believes to be reliable. It is intended for use by persons having technical skill and at their own discretion and risk. Since conditions of use are outside SEPPIC*'s control, SEPPIC* makes no warranties, express or implied, and assumes no liability in connection with any use of this information. Nothing herein is to be taken as a license to operate under or a recommendation to infringe any patents. "Please check with SEPPIC* that you have the most recent version of this document". AQUAYL TM - SEPICAP MP TM - LIPACIDE TM CG - LIPACIDE TM UG - SEPICALM TM S - SEPICALM TM VG and SEPITONIC TM M3 are SEPPIC registered trademarks. SEPPIC* is a subsidiary of the AIR LIQUIDE group. 7 - SEPPIC C357/GB/1/May 7 Création Galbe/37 - Photos : gettyimages SEPPIC Chine Room 51 Jin Tai Building 5 South Mao Ming Road Shanghai - CHINA Tél.: (-1) 1 9 Fax : (-1) 11 9 SEPPIC GmbH Ettore-Bugatti Str Köln-Porz - GERMANY Tél.: +9 () Fax : +9 () SEPPIC Belgium NV Nieuwe Weg 1 Haven 153 B 7 Zwijndrecht BELGIUM Tél.: Fax:

3 AQUAYL TM CLEVER MOISTURISATION! HYDRACONCEPT HAIR - IN N OVATIO N - Two water sources in the hair Essential to maintain the hair s mechanical and protective properties. 1 st moisturising level : SUPERFICIAL nd moisturising level : DEEP Water weakly bound to the surface of the hair. Easily eliminated by hairdryer. Water strongly bound to the hydrophilic part of the hair, in the core of the cuticle Difficult to eliminate. Dry hair (open scales) is a consequence of a loss of the nd level of moisturisation. weakened hair! CONTROL : Bleached hair lock (5x) EM : x % moisture reserves 5.3 % 5.1 %.9 %.7 %.5 % Improvement of deep moisturisation Control 3% AQUAYL TM Curative treatment Rinse-off product 1.5% AQUAYL TM Caucasian hair EM : x Leave on product 1.5% AQUAYL TM Caucasian hair EM : x Rinse-off product 3% AQUAYL TM Asian hair EM : x At 1.5%, AQUAYL TM effectively protects the hair fibre and its appearance (rinse-off or leave on products). At 3%, it restores moisture of damaged hair to the core of cuticle ( rinse-off products). For brilliant hair.

4 HYDRACONCEPT AQUAYL TM FOR FOAM ENHANCEMENT & SMOOTHY SENSATION! HAIR - 1. IMPROVEMENT OF FORMULAS TOLERANCE IN N OVATIO N Irritant Reduction of the SLES irritant effect by the addition of AQUAYL TM Moderatly irritant HET-CAM Index 1% + % % + % % + % 5% + 5% % + % % + % 1% + 9% Evaluation of SLES irritation Evaluation of SLES irritation in presence of AQUAYL TM Slightly irritant No irritant % SLES % AQUAYL TM Irritation effects observed by HET-CAM test : Application of the diluted product to a chorioallantoic membrane of egg. Density Bubble size AQUAYL TM reduces the irritation effects of surfactants such as SLES (Proved with a finished formula SLES % and AQUAYL TM %).. IMPROVEMENT OF FORMULAS SENSORY PROFILE Softness Foam volume 1 st wash Foam volume after dilution SLES % am/ AQUAYL TM % cp SLES alone % am Density Bubble size Softness 1 Foam volume 1 st wash Foam volume after dilution ORAMI TM NS1 % am/ AQUAYL TM % cp Control ORAMI TM NS1 % am Handwashing by panelists with differents formulas, using a standardized method. AQUAYL TM significantly increases the softness and volume of the foam and improves the hygiene formula sensory profile (confirmed also with % of AQUAYL TM and several non ionic surfactants such as ORAMI TM range).

5 SOS SPECIAL ITCHY SCALP! 1. DERMOPROTECTOR EFFECT STRESS NH COOH COOH Healthy scalp (Acid ph) LIPOAMINOACID : Restoration of the acidic ph (COOH free) NH Unbalanced scalp (Basic ph) Redness score Free radicals DNA alteration Cell death Thanks to their structure (COOH free), LIPACIDE TM CG, SEPICALM TM S, SEPICALM TM VG protect the scalp. They restore its acid coat. Very red scalp D Slightly red scalp Normal scalp D 15 D 3 D 5 D Test on volunteers: - Formula 79A - % LIPACIDE TM CG volunteers with capillary seborrheic dermatitis months of treatment, one application every 3 days. Days LIPACIDE TM CG formulated at % removes scalp irritation, from the first month of treatment.. MODULATING EFFECT ON THE INFLAMMATORY CASCADE SEPICALM TM VG Cyclo-oxygenase Prostaglandines Sensation of pain, inflammation STRESSED SCALP Inflammatory enzymes SEPICALM TM VG & SEPICALM TM S SEPICALM TM S Elastase Hyaluronidase Lipooxygenase Destruction of Cutaneous proteins (elastin & collagen) REDNESS, HEAT, PAIN Leukotriens Inflammation SEPICALM TM S and SEPICALM TM VG decrease the concentration of inflammation mediators. They work for a complete anti-stress protection against external agressions. Real feeling of well-being and comfort.

6 YES TO SHINY HAIR, NO TO OILY HAIR! LIPACIDE TM CG LIPACIDE TM UG Finasteride 3 ng/ml am (positive control) AMAZING P FOR HAIR % anti 5α-reductase activity -5 % (.1 % am) -33 % (.1 % am) -35 % Sebum score LIPACIDE TM CG and LIPACIDE TM UG modulate the 5α-reductase activity (enzyme responsable for the sebum production). Very oily scalp and hair D Slightly oily scalp and normal hair D 15 D 3 D 5 Normal scalp and hair D Test on volunteers: - Formula 79A - % LIPACIDE TM CG volunteers with capillary seborrheic dermatitis months of treatment one application every 3 days. Days LIPACIDE TM CG and LIPACIDE TM UG effectively limit the sebum production (clinicaly proven from the first month of treatment with % of LIPACIDE TM CG in the formula). MULTI-FUNCTIONAL THERMO-ACTIVE PROTECTION! STRESS SEPICAP TM MP, thermo-active, superactivated by hairdryer heat (+% of efficiency). ATTACK Limits the formation of lipid peroxides (radical scavenging effect) Prevents keratin breakdown Prevents flaking Restores normal cell division Stimulates protein metabolism Root SEPICAP TM MP restructures and protects stressed hair. Proven efficacy on stressed and damaged hair, demonstrated both with in vivo and in vitro test.

7 ROGRAM CRISIS! LET S COMBAT DANDRUFF! Germ tested : Pytyrosporum ovale (ph = 5) LIPACIDE TM CG LIPACIDE TM UG Minimum Inhibitory Concentration.75 % am.1 % am LIPACIDE TM CG and LIPACIDE TM UG control the proliferation of germs responsible for dandruff. Test on volunteers: - Shampoo - Formula 79A - % LIPACIDE TM CG Volunteers Test on volunteers: - Capillary lotion - Formula 73A - % LIPACIDE TM UG 1 Volunteers Weight of squamae (mg) 1 1 LIPACIDE TM CG and LIPACIDE TM UG clearly improve the state of desquamation. From the first month of treatment, squamae decrease in size and number. Minimum Inhibitory Concentration Squamae Score 1 Many large squamae D FORMULAS FOR FRAGILE HAIR! * p<.5 Before treatment Few small squamae D 15 D 3 D 5 Significant reduction of 55%* squamae After days of treatment No squamae D LIPACIDE TM CG LIPACIDE TM UG UG + CG Bacteria Fungi Days LIPACIDE TM CG and LIPACIDE TM UG allow formulation of products with reduced preservative quantity. (SEPPIC patent). LIPACIDE TM CG reduces effectively the proliferation of bacteria. LIPACIDE TM UG inhibits fungi. Their synergy is indicated for a best result.

8 DON T LET YOUR HAIR DOWN! 1. HELP MAINTAIN HAIR GROWTH Ageing UV, chemical aggressions Air pollution O available Stress, fatigue, diet, cigarette BURNED OUT CELLULAR ENGINE! HAIR CRISIS! Fragile, dull, tired. SEPITONIC TM M3 Cellular chrono-energizer SEPICAP TM MP Preventive protection to the core of stressed hair Cellular division by quantity of DNA (µg/puit) Cells + heat + 53 % of division 5.7 Cells +.5 ppm am SEPICAP TM MP + heat + 17 % of division.3 Cells + 1 ppm am PANTHENOL TM + heat SEPITONIC TM M3 stimulates the synthesis of cellular energy mediator and metabolics (ATP-ADN-proteins) via an optimized cellular respiration. SEPICAP TM MP stimulates the cellular division of stressed keratinocytes. LIPACIDE TM CG LIPACIDE TM UG SEPITONIC TM M3 and SEPICAP TM MP reawaken cellular metabolism. The hair base is toned and revitalised.. LIMITED HAIR LOSS 5α-REDUCTASE 3- HYDROYSTEROIDE DESHYDROGENASE TESTOSTERONE 5α- DEHYDROTESTOSTERONE 5α- ANDROSTANEDIOLS activation of genes responsible for the miniaturization of follicules. premature telogenic phase (hair death). LIPACIDE TM CG and LIPACIDE TM UG are recommended for hair-loss control, thanks to their anti-5α-reductase activity.