PCA derivatives. Our performant range of humectants

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1 PCA derivatives Our performant range of humectants enews August 2015

2 What is PCA? Pyrrolidone carboxylic Acid (PCA) is one of the component of the Natural Moisturizing Factor (NMF) NMF is the natural moisturizing substance which occurs in the stratum corneum of human skin. It plays an essential role in maintaining skin moisture Amino Acids 42% PCA 12% Lactic Acid 11% Urea 7% Others 28% It is also well absorbed by hair. It makes hair soft, shows antistatic properties and improves hair manageability

3 Ajinomoto products We can provide you with PCA and PCA salts, able to protect skin from dryness, to moisturize, to promote elasticity and to help keeping the skin and hair healthy and fresh-looking Pyrrolidone carboxylic Acid (PCA) is an acid type powder Sodium salt of L-pyrrolidone carboxylate (Na PCA) is a natural humectant derived from sodium L- Glutamate Zinc salt of L-pyrrolidone carboxylate (Zn PCA) provides fresh feeling to the skin by decreasing excess of sebum

4 Ajidew NL-50 O Skin moisturizing properties: good properties compared to Glycerin and sodium hyaluronate in both water absorption and water retention Ajidew ZN-100 O Sebum Control: after 4 weeks quantity of sebum decreases O Anti bacterial activity TS data E O Hair moisturizing properties: exhibits good moisture retention property, similar to hydrolyzed collagen ones MIC Value (μg/ml) Starains ZN-100 Escherichia coli 1250 Pseudomonas aeruginosa 7500 Staphylococcus aureus 938 MRSA 938 Streptococcus mutans 625 Propionibacterium acnes 1875 Candida albicans 1875 Aspergillus niger 1250 Cladosporium cladosporioides 938 Trichophyton mentagrophytes 1875 Malassezia furfur 313 O Anti aging properties Inhibits collagen degradation and wrinkle formation

5 What else? Our Amino Acid cocktail is the humectant blend, containing a combination of PCA-Na, PCA, Sodium Lactate and eleven kinds of amino acids. It has been developed for the efficient application of PCA and amino acids in hair care preparation, based on the Amino Acids composition of the proteins of the Cell Membrane Complex (CMC, intercellular cement for cuticle and cortex) Components Conc. (%) Effects Sodium PCA and PCA 20 Moisturizing, conditioning, improvement of colour retention Arginine 7 Amino Acids Mix 7 Conditioning, improvement of PCA absorption Damage care (Alanine increases hair surface hydrophobicity, Histidine and Phenylalanine improve tensile strength) Sodium Lactate 12 Moisturizing Aspartic Acid 4 ph adjustment Water 50

6 Products from the market AVON, Poland Daily Cream SPF 15 Positioning: Moisturising, Hydrating, for sensitive skin Lavera, Germany Sensitive 24h Deodorant Roll-On Positioning: Organic, Long-Lasting, For Sensitive Skin, Environmentally Friendly Product Jo Hansford, UK Voluminous Spray for hair Positioning: Fortified, Damaged Hair, Brightening / Illuminating, Long-Lasting, Protects Against Elements Caudalie, France Purifying Mask Positioning: Anti-Acne, Skin Disorders, Mattifying Mintel data

7 Guide formulations Leave-on conditioner ALTP-03 Acrylate10-30 alkyl acrylate crosspolymer % w/w 0.40 A Moisturizing gel AMJ-1 Water % w/w balanc e Butylene glycol 5.00 Glycerin 4.00 Ajidew NL Water Hydroxylated lecithin, glycerin 0.10 A Hair shampoo NSAI-ZN02 % w/w Sodium lauryl sulfoacetate 4.00 Lauryl glucoside 9.00 Amisoft CS Preservatives q.s. A Arginine C 0.37 Water Butylene Glycol 3.00 PEG-40 hydrogenated castor oil 0.20 PEG-40 hydrogenated castor oil PCA isostearate 0.20 B Pentasodium pentetate 0.05 PEG-40 hydrogenated castor oil PCA isostearate 0.20 Eldew PS-203R 0.15 Trisiostearine 0.10 Sodium hyaluronate 0.01 Water B Eldew PS C Prodew P-DS B Glyceryl caprate 3.00 C Amisafe AL D Fragrance q.s. E Magnesium chloride 1.50 F G Citric acid 0.50 Water balanc e Ajidew ZN Water 5.00 This sulfate-free hair shampoo is formulated for normal to oily hair and scalp Ajidew ZN-100 is a multifunctional ingredient that has sebum control and antibacterial properties Eldew SL Dimethicone and Laureth-4 and Laureth C Preservative q.s. Alcohol Fragrance q.s. Prodew Disodium EDTA 0.02 Water balance The leave-on hair conditioner nourishes hair with Amino Acids. This lightweight formula can be applied either to damp or to dry hair D E F Water 5.00 Acrylate/C alkyl acrylate crosspolymer 0.40 Water Arginine C 0.41 Water 5.00 CAE 0.10 Water 5.00 Fragrance q.s. A light touch gel moisturizer in which amino-acid based moisturizers and emollient help the skin keeping moisture. Free from alcohol and parabens. Challenge test result is available

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