Product Information. Components. Transport Information

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1 Coulter TM Product Name HmX PAK Part Number Product Information Kit MSDS : Rev. AA Doc. ID Issued (day/month/year) 07/03/2000 Series Name: COULTER HmX System Components Description Transport Information Transportation of this product is not regulated under ICAO, IATA, US DOT, European ADR or Canadian TDG Beckman Coulter, Inc. Global MSDS English

2 Coulter TM MATERIAL SAFETY DATA SHEET Section 1 Company and Product Identification Product Name Part Number Component of P/N HmX PAK Doc. ID Issued (day/month/year) 07/03/2000 Manufacturer Distributor and Emergency Phone No. Beckman Coulter, Inc Harbor Blvd. Fullerton, CA , U.S.A. Refer to attached list, Document ID: , for local distributor and emergency phone numbers. Section 2 Composition and Information on Ingredients Hazardous Ingredients: Meets Hazardous Criteria: Chemical Name CAS # % by wt. EU US OSHA WHMIS Formic Acid <0.5 No Yes Exempt See Section 15 Regulatory Information for additional information on ingredient hazard classifications. Emergency Overview Section 3 Hazards Identification Light yellow; Clear; Liquid; Odorless Nonflammable aqueous solution. Skin, eye, respiratory, and gastrointestinal irritant. May be harmful or fatal if swallowed. Physical Hazards Potential Health Effects Summary No physical hazards were determined from a review of available literature. Exposure may result in irritation of skin, eyes, and mucous membranes. See Section 11 Toxicological Information for more detailed health information. Product Hazard Classifications EU: WHMIS: Exempt US OSHA: Hazardous Inhalation Eye Contact Section 4 First Aid Measures If product is inhaled, move exposed individual to fresh air. If individual is not breathing, begin artificial respiration immediately and obtain medical attention. If product is splashed in eyes, wash eyes under gently running water for several minutes, making sure that the eyelids are held open. If irritation or redness develops, obtain medical attention. Skin Contact In case of skin contact, flush with copious amounts of water for at least 15 minutes. Call a physician.

3 Ingestion Page 3 of 11 Section 4 First Aid Measures (Continued) If ingested, wash out mouth with water. Call a physician. Section 5 Fire Fighting Measures Flash Point Flammable Limits Autoignition Temp. Extinguishing Media Special Fire and Explosion Hazards Hazardous Combustion Products Protective Equipment for Firefighters Use extinguishing media suitable for surrounding fire. No special hazards determined. Due to the composition and volume of this product, combustion products generated from it are not expected to present a significant hazard. Self-contained breathing apparatus is recommended for firefighters. Section 6 Accidential Release Measures Personal Precautions Spill and Leak Procedures Environmental Precautions Avoid skin contact. Use good laboratory procedures. Wipe up material carefully and place in container suitable for disposal. Contain spill to prevent migration. Section 7 Handling and Storage Handling Precautions Recommended Storage Conditions Avoid inhaling, ingestion, and contact with eyes and skin. Keep away from incompatible material. To maintain efficacy, store according to the instructions in the product labeling. Section 8 Exposure Controls and Personal Protection Exposure Limits US OSHA: Formic Acid 5 ppm TWA; 9 mg/m3 TWA ACGIH: Formic Acid DFG MAK: Formic Acid Engineering Controls 10 ppm STEL; 5 ppm TWA 5 ppm MAK; 9.5 mg/m3 MAK; 2 x normal MAK (5 min momentary value); don t exceed 8 times during shift Use in well ventilated area.

4 Page 4 of 11 Section 8 Exposure Controls and Personal Protection (Continued) Respiratory Protection Eye Protection Skin Protection Under normal conditions, the use of this product should not require respiratory protection. If overexposure should occur and ventilation is not adequate to maintain airborne concentrations at acceptable levels, the use of respiratory protection should be evaluated by a qualified professional. Safety glasses or chemical goggles should be worn to prevent eye contact. Impervious gloves should be worn to prevent skin contact. Section 9 Physical and Chemical Properties Physical State Liquid Color Light yellow Transparency Clear Odor Odorless Odor Threshold Formic Acid no geometric mean air odor threshold ph 2.7 Boiling Point Melting Point Specific Gravity 1.0 Vapor Pressure Vapor Density Evaporation Rate Coefficient of Water/Oil Distribution Percent Volatiles Solubility Water Organic Miscible Section 10 Stability and Reactivity Stability Hazardous Incompatibilities Hazardous Decomposition Products Conditions to Avoid Stable under normal temperatures and pressures. Strong Oxidizers Perchloric Acid Strong bases Permanganates When stored as labeled, no known hazardous decomposition products are formed during the shelf-life of this product. Keep away from incompatible material.

5 Page 5 of 11 Section 11 Toxicological Information Toxicity Data for Hazardous Ingredients Formic Acid Inhalation LC50 Rat : 15 gm/m3/15m; Inhalation LC50 Mouse : 6200 mg/m3/15m;oral LD50 Rat : 1100 mg/kg; Oral LD50 Mouse : 700 mg/kg Primary Routes of Exposure Potential Effects of Acute Exposure Potential Effects of Chronic Exposure Symptoms of Overexposure Carcinogenicity Other Effects Common routes of entry include inhalation, ingestion and eye/skin contact. Specific paths of concern for potentially infectious materials are skin puncture, contact with broken skin, contact with mucous membranes and inhalation of aerosolized material. Inhalation of dilute acidic mists may cause respiratory tract irritation or burns to mucous membranes resulting in coughing, choking and difficulty in breathing. Results of skin contact may range from irritation and inflammation to burns with blistering. Eye contact may cause severe irritation with painful, watery eyes or burns with possible blindness. Ingestion may cause irritation or burns to the mouth and throat resulting in pain, difficulty in speaking and swallowing, intense thirst, nausea and vomiting. Depending upon concentration and duration of exposure to dilute acidic mist, effects may be similar to those described for acute exposure. Repeated or prolonged contact with dilute acid may result in dermatitis and conjunctivitis with inflamed skin and eyes. Symptoms of overexposure may include: redness, burning and watering of the eyes; dry, red, cracked skin; coughing and difficult breathing; nausea and vomiting. No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA or 67/548/EEC Annex I. Reproductive effects have been reported in animal studies. Conditions Aggravated by Exposure Individuals with eye, skin or kidney disorders may find these conditions aggravated by exposure to this product. Section 12 Ecological Information Ecotoxicity Biodegradability Mobility Toxic to fish and other water organisms. No information available. No information available. Waste Disposal Section 13 Disposal Considerations Dispose of waste product, unused product and contaminated packaging in compliance with federal, state and local regulations. If unsure of the applicable requirements, contact the authorities for information. Section 14 Transport Information Transportation of this product is not regulated under ICAO, IATA, US DOT, European ADR or Canadian TDG.

6 Page 6 of 11 Section 15 Regulatory Information US Federal and State Regulations SARA 313 CERCLA RG s, 40 CFR California Proposition 65 Massachusetts MSL New Jersey Dept. of Health RTK List Pennsylvania RTK EU Dangerous Ingredients None Formic Acid is subject to reporting requirements of Section 313, Title III of SARA. Formic Acid is listed. No ingredients listed Formic Acid is listed. magnesium nitrate is listed. Magnesium Chloride is listed. Formic Acid is listed. magnesium nitrate is listed. Magnesium Chloride is listed. Formic Acid is listed. magnesium nitrate is listed. Magnesium Chloride is listed. Canada This product is exempt from WHMIS label and MSDS requirements. PIN: Ingredients on Ingredient Disclosure List: Ingredients with unknown toxicological properties: Formic Acid Product is exempt Section 16 Other Information For further information, please contact your local Beckman Coulter representative. WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS. Printed in U.S.A.

7 Coulter TM MATERIAL SAFETY DATA SHEET Section 1 Company and Product Identification Product Name Part Number Component of P/N HmX PAK Doc. ID Issued (day/month/year) 07/03/2000 Manufacturer Distributor and Emergency Phone No. Beckman Coulter, Inc Harbor Blvd. Fullerton, CA , U.S.A. Refer to attached list, Document ID: , for local distributor and emergency phone numbers. Section 2 Composition and Information on Ingredients Hazardous Ingredients: Emergency Overview None Section 3 Hazards Identification Colorless; Clear; Liquid; Odorless Nonflammable aqueous solution. Does not meet EU, OSHA or WHMIS criteria for hazardous materials. Physical Hazards Potential Health Effects Summary Product Hazard Classifications No physical hazards were determined from a review of available literature. This product does not meet EU, OSHA or WHMIS criteria for hazardous materials. EU: WHMIS: Exempt US OSHA: Section 4 First Aid Measures Inhalation Eye Contact Skin Contact Ingestion If product is inhaled, move exposed individual to fresh air. If individual is not breathing, begin artificial respiration immediately and obtain medical attention. If product is splashed in eyes, wash eyes under gently running water for several minutes, making sure that the eyelids are held open. If irritation or redness develops, obtain medical attention. In case of skin contact, wash area with soap and water. Rinse well with water. If ingested, wash out mouth with water. Call a physician. Section 5 Fire Fighting Measures Flash Point Flammable Limits Autoignition Temp.

8 Page 8 of 11 Section 5 Fire Fighting Measures (Continued) Extinguishing Media Special Fire and Explosion Hazards Hazardous Combustion Products Protective Equipment for Firefighters Use extinguishing media suitable for surrounding fire. No special hazards determined. Due to the nature and volume of this product, the type and amount of combustion products are negligible. Self-contained breathing apparatus is recommended for firefighters. Section 6 Accidential Release Measures Personal Precautions Spill and Leak Procedures Environmental Precautions Avoid skin contact. Use good laboratory procedures. Wipe up material carefully and place in container suitable for disposal. Contain spill to prevent migration. Section 7 Handling and Storage Handling Precautions Recommended Storage Conditions Use good laboratory procedures; avoid eye and skin contact. Keep away from incompatible material. To maintain efficacy, store according to the instructions in the product labeling. Section 8 Exposure Controls and Personal Protection Exposure Limits US OSHA: None established ACGIH: None established DFG MAK: Engineering Controls Respiratory Protection Eye Protection Skin Protection None established Use in well ventilated area. Under normal conditions, the use of this product should not require respiratory protection. If overexposure should occur and ventilation is not adequate to maintain airborne concentrations at acceptable levels, the use of respiratory protection should be evaluated by a qualified professional. Safety glasses or chemical goggles should be worn to prevent eye contact. Impervious gloves should be worn to prevent skin contact. Section 9 Physical and Chemical Properties Physical State Liquid

9 Page 9 of 11 Section 9 Physical and Chemical Properties (Continued) Color Colorless Transparency Clear Odor Odorless Odor Threshold ph 11.0 Boiling Point Melting Point Specific Gravity Vapor Pressure Vapor Density Evaporation Rate Coefficient of Water/Oil Distribution Percent Volatiles Solubility Water Organic C Miscible Section 10 Stability and Reactivity Stability Hazardous Incompatibilities Hazardous Decomposition Products Conditions to Avoid Stable under normal temperatures and pressures. Strong acids When stored as labeled, no known hazardous decomposition products are formed during the shelf-life of this product. Keep away from incompatible material. Section 11 Toxicological Information Toxicity Data for Hazardous Ingredients Primary Routes of Exposure Potential Effects of Acute Exposure Potential Effects of Chronic Exposure Symptoms of Overexposure Carcinogenicity Other Effects The most likely routes of exposure are skin and eye contact and inhalation. None identified. None identified. No specific symptoms identified. No ingredients in this product are listed as carcinogens by ACGIH, IARC, NTP, OSHA or 67/548/EEC Annex I. None identified.

10 Page 10 of 11 Section 11 Toxicological Information (Continued) Conditions Aggravated by Exposure None identified. Section 12 Ecological Information Ecotoxicity Biodegradability Mobility No information available. No information available. No information available. Section 13 Disposal Considerations Waste Disposal Dispose of waste product, unused product and contaminated packaging in compliance with federal, state and local regulations. If unsure of the applicable requirements, contact the authorities for information. Section 14 Transport Information Transportation of this product is not regulated under ICAO, IATA, US DOT, European ADR or Canadian TDG. US Federal and State Regulations Section 15 Regulatory Information SARA 313 CERCLA RG s, 40 CFR California Proposition 65 Massachusetts MSL New Jersey Dept. of Health RTK List Pennsylvania RTK No ingredients listed No ingredients listed No ingredients listed Sodium Sulfate is listed. No ingredients listed Sodium Sulfate is listed. EU Dangerous Ingredients None Canada This product is exempt from WHMIS label and MSDS requirements. PIN: Ingredients on Ingredient Disclosure List: Ingredients with unknown toxicological properties: Sodium Carbonate Product is exempt

11 Page 11 of 11 Section 16 Other Information For further information, please contact your local Beckman Coulter representative. WHILE BECKMAN COULTER, INC. BELIEVES THE INFORMATION CONTAINED HEREIN IS VALID AND ACCURATE, BECKMAN COULTER MAKES NO WARRANTY OR REPRESENTATION AS TO ITS VALIDITY, ACCURACY, OR CURRENCY. BECKMAN COULTER SHALL NOT BE LIABLE OR OTHERWISE RESPONSIBLE IN ANY WAY FOR USE OF EITHER THIS INFORMATION OR MATERIALS TO WHICH IT APPLIES. DISPOSAL OF HAZARDOUS MATERIALS MAY BE SUBJECT TO LOCAL LAWS OR REGULATIONS. Printed in U.S.A.

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