Moisturizing agent with aesthetic performance. Table of Contents

Transcription

1 HYDROVANCE Moisturizing agent with aesthetic performance. Table of Contents Section 1: Sales Specifications for HYDROVANCE Section 2: Technical Sales Bulletin for HYDROVANCE Section 3: Regulatory Information for HYDROVANCE Section 4: MSDS for HYDROVANCE Links

2 Section 1 Sales Specifications for HYDROVANCE

3 HYDROVANCE moisturizing agent INCI Name: Hydroxyethyl Urea Specification Appearance Clear, colorless to slightly yellow aqueous solution, free of particulates Parameter Limits % Solids Brookfield Viscosity (cps) < 200 ph Measurements Brookfield Viscosity is measured using Spindle #1, 20 RPM, 25 C. Issued: No representation or warranty, expressed or implied, is made as to the accuracy or completeness of the information of data contained herein and AkzoNobel Surface Chemistry shall have no obligation or liability whatsoever with respect to any such information or data, including, but not limited to, any liability for infringement of patent or other industrial property rights. AkzoNobel surface Chemistry disclaims all implied warranties of merchantability and fitness for a particular purpose. AkzoNobel Surface Chemistry shall in no event be liable for incidental or consequential damages, including, without limitation, lost profit, loss of income, loss of business opportunity and any other related costs and expenses.

4 Section 2 Technical Sales Bulletin for HYDROVANCE

5 AkzoNobel Surface Chemistry Personal Care HYDROVANCE Moisturizing Agent HYDROVANCE Moisturizing Agent INCI: Hydroxyethyl Urea Moisturizing Agent with Excellent Aesthetic Properties INTRODUCTION The use of benefit agents in skin care applications is forecasted to grow for the foreseeable future because consumers are demanding that their skin care products reduce fine lines and facial wrinkles, improve elasticity and firmness of skin, and provide higher levels and longer lasting skin hydration. HYDROVANCE moisturizing agent provides excellent moisturization, increases skin elasticity, and enhances tactile sensory properties of formulations. HYDROVANCE moisturizing agent has broad compatibility, offering cosmetic chemists the freedom to formulate over a wide ph range and with a large variety of raw materials. HYDROVANCE moisturizing agent, based on Hydroxyethyl Urea, is supplied as an aqueous solution. O HO CH 2 CH 2 N C H NH 2 Hydroxyethyl Urea APPLICATION AREAS Facial, body, hand, and foot creams and lotions, moisturizing products, anti-aging products, shower and bath products, facial cleansers, sun protection products, self-tanning products, color cosmetics, depilatories, antiperspirants and deodorants, foot care, hair styling products, hair shampoos and conditioners, hair treatments, hair color products FEATURES / BENEFITS Moisturization equal to glycerin Non-tacky feel Excellent aesthetics Nonionic broad compatibility Preservative free Little to no impact on formula viscosity SUGGESTED USE LEVELS, AS SUPPLIED Leave-On Moisturizing Products (Creams, Lotions, Gels, etc.): 1-10% Rinse-Off Products (Shampoo, Conditioner, Bodywash): 1-20% Sun Protection Products: 1-10% Color Cosmetics: 1-10% Suggested ph Range of final formulations: 5-8 Page 1 of 8 Europe: Sempach-Station, Switzerland, T: +41 (0) , F: +41 (0) , e: personalcare.europe@akzonobel.com Americas: Bridgewater, New Jersey, U.S.A., T: , F: , e: personalcare.usa@akzonobel.com South America: Itupeva, SP, Brazil, T: , F: , e: personalcare.southamerica@akzonobel.com Asia/Pacific: Hong Kong, Tel: , Fax: , personalcare.asia@akzonobel.com

6 AkzoNobel Surface Chemistry Personal Care HYDROVANCE Moisturizing Agent Some formulations may require the use of a stabilization system, to prevent the formulation from drifting to higher ph during stability testing. Potential stabilization systems include: Low molecular weight esters, especially triethyl citrate Cyclic esters or lactones Buffer systems, especially lactates and phosphates More detailed information on these stabilization systems can be found in the Formulating with HYDROVANCE Moisturizing Agent paper. FORMULATION GUIDELINES HYDROVANCE Moisturizing Agent is easily incorporated into water, or the water phase of an emulsion, at ambient or elevated temperature conditions. PERFORMANCE PROPERTIES Moisturization Efficacy Measured by Corneometer Moisturizing efficacy is measured by the ingredient s ability to increase the water content in the stratum corneum. This is usually measured using a Corneometer. The measuring principle of the Corneometer is based on capacitance measurements of the dielectric medium. Any change in the dielectric constant due to skin surface hydration variation alters the capacitance. The dielectric constant of the stratum corneum increases with increasing water content. The Corneometer measures the difference in stratum corneum hydration before and after application of a cosmetic product or other skin treatment. Through Corneometer testing, it has been confirmed that HYDROVANCE moisturizing agent increases the water content of the stratum corneum. Gels with 5% active level of either HYDROVANCE moisturizing agent or glycerin were applied on a 4cm square area on the volar forearm of panelists with dry skin. Moisture levels of the stratum corneum were measured prior to application of the gel and 15 minutes, 1, 2, 4, and 6 hours after application. The moisture level of the treated areas was normalized to untreated skin at each time interval. The moisture level of untreated skin did not fluctuate considerably over the period of the evaluation. (Figure 1) Figure 1 Moisturizing Efficacy by Corneometer (35%RH/21 C) BASELINE 15 Minutes 1 Hour 2 Hour 4 Hour 6 Hour 2 4 Hour HYDROVANCE* Glycerin Carbomer Gels, based on 5% active levels Page 2 of 8 Europe: Sempach-Station, Switzerland, T: +41 (0) , F: +41 (0) , e: personalcare.europe@akzonobel.com Americas: Bridgewater, New Jersey, U.S.A., T: , F: , e: personalcare.usa@akzonobel.com South America: Itupeva, SP, Brazil, T: , F: , e: personalcare.southamerica@akzonobel.com Asia/Pacific: Hong Kong, Tel: , Fax: , personalcare.asia@akzonobel.com

7 AkzoNobel Surface Chemistry Personal Care HYDROVANCE Moisturizing Agent This study demonstrates that HYDROVANCE moisturizing agent delivers moisturization efficacy comparable to glycerin. Based on statistical analysis of the data, there is no significant difference between these two ingredients in this study. Moisturization Efficacy Measured by Gas Bearing Electrodynamometer A Gas Bearing Electrodynamometer (GBE) measures the pliability or surface elasticity of the stratum corneum in vivo and has been shown to correlate directly with the water content of the skin. Through GBE testing, it has been confirmed that HYDROVANCE moisturizing agent increases the elasticity of the stratum corneum. Glycerin is known to be an effective plasticizer of the stratum corneum. A clinical study compares HYDROVANCE moisturizing agent with glycerin. Gels, with either 5% active level of HYDROVANCE moisturizing agent or glycerin, were applied to the volar forearm of panelists with dry skin. Skin elasticity was measured via a GBE prior to application and 15 minutes, 1, 2, 4, and 8 hours after application. The results are reported as a percent improvement in the skin's Dynamic Spring Rate (DSR) after application of the moisturizing gels. Figure 2 Skin Flexibility/Suppleness by Gas Bearing Electrodynamometer DSR (gm/mm) % Improvement Compared to Baseline min 15 min 1 hour 2 hour 4 hour 8 hour 24 hour Time HYDROVANCE moisturizing agent Glycerin HYDROVANCE moisturizing agent has efficacy comparable to glycerin for skin elasticity. Based on statistical analysis, there is no significant difference between the two ingredients in this study. (Figure 2) Long Term Moisturization A Long Term Clinical Moisturization study measures the ability of an ingredient to improve the overall condition of skin with extended, consistent use. This clinical study is made up of three individual evaluations: Clinical Grading by trained dermatologists, Corneometer testing, Image Analysis for Skin Dryness. Five panelists were used to evaluate the long-term moisturization of HYDROVANCE Page 3 of 8 Europe: Sempach-Station, Switzerland, T: +41 (0) , F: +41 (0) , e: personalcare.europe@akzonobel.com Americas: Bridgewater, New Jersey, U.S.A., T: , F: , e: personalcare.usa@akzonobel.com South America: Itupeva, SP, Brazil, T: , F: , e: personalcare.southamerica@akzonobel.com Asia/Pacific: Hong Kong, Tel: , Fax: , personalcare.asia@akzonobel.com

8 AkzoNobel Surface Chemistry Personal Care HYDROVANCE Moisturizing Agent moisturizing agent compared to glycerin. Aqueous solutions, with 5% active level of either HYDROVANCE moisturizing agent or glycerin, were tested. The panelists applied the test products to the dry skin on the outside of the assigned leg between the knee and ankle area, twice a day for three weeks. All evaluations were performed pre-treatment, at weeks 2 and 3 of treatment, and after a one week regression period. The one week regression evaluates the skin properties after 3 weeks of treatment and 1 week of no treatment to determine if effects are sustained without continued treatment Clinical Grading Trained dermatologists assigned a clinical grade to the skin based on the appearance and condition of the skin at each evaluation point. The clinical grading was assigned on a scale from 0, no dryness, to 3, severe dryness. The mean clinical grading for each evaluation point is presented in Figure 3. Severe dryness Figure 3 Clinical Evaluation of Dryness Mean Values Clinical Grade No dryness BASELINE Week 2 Week 3 1 Week Regression Time HYDROVANCE moisturizing agent Glycerin The clinical grading results show a significant improvement in dryness for both HYDROVANCE moisturizing agent and glycerin. Both ingredients show that an improvement in skin moisturization is sustained one week after the treatment ended. No significant difference is observed between HYDROVANCE moisturizing agent and glycerin in this study. Moisturization Evaluation by Corneometer A Corneometer measured the relative moisture levels in the skin throughout the Long Term Moisturization study. The mean moisture level for each evaluation point are shown in Figure 4. Page 4 of 8 Europe: Sempach-Station, Switzerland, T: +41 (0) , F: +41 (0) , e: personalcare.europe@akzonobel.com Americas: Bridgewater, New Jersey, U.S.A., T: , F: , e: personalcare.usa@akzonobel.com South America: Itupeva, SP, Brazil, T: , F: , e: personalcare.southamerica@akzonobel.com Asia/Pacific: Hong Kong, Tel: , Fax: , personalcare.asia@akzonobel.com

9 AkzoNobel Surface Chemistry Personal Care HYDROVANCE Moisturizing Agent 35 Figure 4 Moisturizing Efficacy by Corneometer Long Term Moisturization Study 30 Relative Moisture Level Pre-treatment Week 2 Week 3 1 Week Regression HYDROVANCE moisturizing agent Glycerin The Corneometer data shows that HYDROVANCE moisturizing agent has efficacy comparable to glycerin for skin moisturization. The maximum moisturization level for both ingredients is achieved after 3 weeks of treatment. The one week regression results are similar to those obtained after 2 weeks of treatment. There is no significant difference in skin moisturization efficacy between these two ingredients at any point during the study. Image Analysis for Skin Dryness Image Analysis is used to assess skin dryness, reported as the scaliness index (S.I.) of skin. The skin is first defatted and then a D-Squame adhesive disc is applied with standard pressure. The D-Squame disc is removed from the skin with the attached scales. This sample is used for image analysis to determine the S.I. of skin, which is calculated on the assumption that the whiteness of the scales is proportional to their thickness. A thicker, and therefore, whiter scale has a higher S.I. value and shows increased hydration of the stratum corneum. Higher S.I. values mean better moisturization efficacy. Page 5 of 8 Europe: Sempach-Station, Switzerland, T: +41 (0) , F: +41 (0) , e: personalcare.europe@akzonobel.com Americas: Bridgewater, New Jersey, U.S.A., T: , F: , e: personalcare.usa@akzonobel.com South America: Itupeva, SP, Brazil, T: , F: , e: personalcare.southamerica@akzonobel.com Asia/Pacific: Hong Kong, Tel: , Fax: , personalcare.asia@akzonobel.com

10 AkzoNobel Surface Chemistry Personal Care HYDROVANCE Moisturizing Agent 0.6 Figure 5 D-SQUAME Analysis of Dryness Relative Scaliness Index (S.I.) BASELINE Week 2 Week 3 1 Week Regression Time HYDROVANCE moisturizing agent Glycerin This image analysis study demonstrates that HYDROVANCE moisturizing agent and glycerin provide a similar Scaliness Index at each point of the Long Term Moisturization study. There is no significant difference between the two ingredients in this study. The results of the Clinical Grading, Corneometer Measurements, and Image Analysis show that HYDROVANCE moisturizing agent provides similar Long Term Moisturization to glycerin. Expert Sensory Evaluation of Raw Materials Sensory Evaluation involves the detection and description of a product s sensory characteristics. For this study, an expert panel assessed the skin sensory characteristics of personal care moisturizing ingredients as supplied under controlled conditions on a scale from 0 (no presence of a particular attribute) to 100 (very strong presence of a particular attribute). The expert panelists identified statistical differences among the sensory attributes of the test samples. The moisturizing agents assessed were HYDROVANCE moisturizing agent (50% aqueous solution), glycerin (99.5% aqueous solution), sodium pyrrolidone carboxylic acid (Na PCA) (50% aqueous solution), and urea (45% aqueous solution). The conclusion from this study shows that these raw materials provide different rubout and afterfeel experiences. Compared to the other raw materials, HYDROVANCE moisturizing agent and urea are higher in wetness and spreadability during rubout. At afterfeel, they are lower than untreated skin for gloss, have little to no stickiness, and provide slipperiness similar to untreated skin. The thickness and amount of residue are very low for these two raw materials. Page 6 of 8 Europe: Sempach-Station, Switzerland, T: +41 (0) , F: +41 (0) , e: personalcare.europe@akzonobel.com Americas: Bridgewater, New Jersey, U.S.A., T: , F: , e: personalcare.usa@akzonobel.com South America: Itupeva, SP, Brazil, T: , F: , e: personalcare.southamerica@akzonobel.com Asia/Pacific: Hong Kong, Tel: , Fax: , personalcare.asia@akzonobel.com

11 AkzoNobel Surface Chemistry Personal Care HYDROVANCE Moisturizing Agent Figure 6 displays the results of the evaluation for absorbency, gloss, stickiness, and amount of residue at the immediate afterfeel. In all of these attributes, HYDROVANCE moisturizing agent is rated significantly better than glycerin and better than or equal to the other moisturizing agents tested. Figure 6 Absorbancy Gloss on Skin Stickiness Amount of Residue HYDROVANCE Glycerin NaPCA Urea STORAGE AND HANDLING HYDROVANCE moisturizing agent should be protected from freezing. Avoid extreme temperatures during storage. Good industrial hygiene practices should be followed when working with this polymer. Please read the MSDS before working with this or any other chemical. This product is best used within 12 months of manufacture. HEALTH AND SAFETY A health and safety summary for HYDROVANCE moisturizing agent is available on request. Information on HYDROVANCE moisturizing agent relating to EU Cosmetics Directive 76/768/EEC is also available upon request. The suitability of the final formulations should be confirmed in all respect by appropriate evaluation. The marketer is advised to evaluate the final formulation with regard to performance and health and safety. Page 7 of 8 Europe: Sempach-Station, Switzerland, T: +41 (0) , F: +41 (0) , e: personalcare.europe@akzonobel.com Americas: Bridgewater, New Jersey, U.S.A., T: , F: , e: personalcare.usa@akzonobel.com South America: Itupeva, SP, Brazil, T: , F: , e: personalcare.southamerica@akzonobel.com Asia/Pacific: Hong Kong, Tel: , Fax: , personalcare.asia@akzonobel.com

12 AkzoNobel Surface Chemistry Personal Care HYDROVANCE Moisturizing Agent BIODEGRADABILITY The CO 2 Evolution Modified Strum Test (OECD 301B) demonstrated the HYDROVANCE moisturizing agent is readily biodegradible. Rev The information given and the recommendations made herein are based on our research and are believed to be accurate but no guarantee of their accuracy is made. In every case we urge and recommend that purchasers before using any product in full scale production make their own tests to determine to their own satisfaction whether the product is of acceptable quality and is suitable for their particular purposes under their own operating conditions. The results of toxicity testing of the polymers used in the formulations are found in the respective technical literature, the safety of the formulation has not been established by testing. The suitability of the final formulation should be confirmed in all respects by appropriate evaluation. No representative of ours has any authority to waive or change the foregoing provisions but, subject to such provisions, our engineers are available to assist purchasers in adapting our products to their needs and to the circumstances prevailing in their business. Nothing contained herein shall be construed to imply the nonexistence of any relevant patents or to constitute a permission, inducement or recommendation to practice any invention covered by any patent, without the authority from the owner of this patent. We also expect purchasers to use our products in accordance with the guiding principles of the Chemical Manufacturers Association's Responsible Care program. Page 8 of 8 Europe: Sempach-Station, Switzerland, T: +41 (0) , F: +41 (0) , e: personalcare.europe@akzonobel.com Americas: Bridgewater, New Jersey, U.S.A., T: , F: , e: personalcare.usa@akzonobel.com South America: Itupeva, SP, Brazil, T: , F: , e: personalcare.southamerica@akzonobel.com Asia/Pacific: Hong Kong, Tel: , Fax: , personalcare.asia@akzonobel.com

13 Section 3 Regulatory Information for HYDROVANCE

14 HYDROVANCE moisturizing agent Regulatory Information Parameter CAS Number USA (TSCA) Yes Europe Contains EINECS listed ingredients Issued: No representation or warranty, expressed or implied, is made as to the accuracy or completeness of the information of data contained herein and AkzoNobel Surface Chemistry shall have no obligation or liability whatsoever with respect to any such information or data, including, but not limited to, any liability for infringement of patent or other industrial property rights. AkzoNobel Surface Chemistry disclaims all implied warranties of merchantability and fitness for a particular purpose. AkzoNobel Surface Chemistry shall in no event be liable for incidental or consequential damages, including, without limitation, lost profit, loss of income, loss of business opportunity and any other related costs and expenses.

15 Monday, August 03, 2009 Re: HYDROVANCE Material Origin BSE To: Whom it may concern, AkzoNobel Surface Chemistry Personal Care has completed a review of the ingredients used in the manufacture of our personal care products. As a result of this exercise, we are able to certify that the below product is free of any animal derived ingredients. HYDROVANCE moisturizing agent Specifically, this product is derived from synthetic sources. Sincerely, David Bower Regulatory, U.S

16 Section 4 MSDS for HYDROVANCE

17 PRODUCT NUMBER December-2008 *** MATERIAL SAFETY DATA SHEET *** 1. CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NUMBER PRODUCT NAME HYDROVANCE Moisturizing agent MANUFACTURER Akzo Nobel Surface Chemistry LLC 525 West Van Buren Street Chicago, IL USA EMERGENCY PHONES: MEDICAL: (Health & Safety Call Center-24 hours) TRANSPORT: CHEMTREC: (24 hours) CHEMTREC International: (call collect) CANUTEC: (24 hours) MSDS Requests/Customer Service: See phone numbers in Section COMPOSITION/INFORMATION ON INGREDIENTS COMPONENT CAS NUMBER CONCENTRATION (% by weight) None classified as hazardous under the OSHA Hazard Communication Standard (29CFR ). 3. HAZARDS IDENTIFICATION EMERGENCY OVERVIEW EYE SKIN CONTACT INHALATION INGESTION Not considered as hazardous. Light yellow Liquid No odor May cause eye irritation. Repeated or prolonged skin contact may result in mild irritation. Vapors and/or aerosols which may be formed at elevated temperatures may be irritating to eyes and respiratory tract. Ingestion may cause irritation of the gastrointestinal tract. PAGE 1 OF 6

18 PRODUCT NUMBER December FIRST-AID MEASURES EYE SKIN CONTACT INHALATION INGESTION Immediate medical attention is not required. Irrigate with eyewash solution or clean water until pain is relieved. If symptoms develop, obtain medical attention. Immediate medical attention is not required. Wash skin with soap and water. If symptoms develop, obtain medical attention. Immediate medical attention is not required. Remove to fresh air. Get medical attention if irritation persists. Treat symptomatically and supportively. Get medical attention. DO NOT attempt to give anything by mouth to an unconscious person. 5. FIREFIGHTING MEASURES AUTOIGNITION Not available FLASH POINT > 100 C EXTINGUISHING MEDIA Alcohol Foam; CO2; Dry Chemical; Foam; Water Fog SPECIAL FIREFIGHTING PROCEDURES Fire fighters should be equipped with self-contained breathing apparatus to protect against potentially toxic and irritating fumes. FIRE & EXPLOSION HAZARDS This is a water-based product and presents no particular fire or explosion hazard. HAZARDOUS COMBUSTION PRODUCTS Thermal decomposition may release toxic and/or hazardous gases. LOWER EXPLOSION LIMIT (%) Not applicable UPPER EXPLOSION LIMIT (%) Not applicable 6. ACCIDENTAL RELEASE MEASURES SPILL AND LEAK PROCEDURES Absorb spillages onto sand, earth or any suitable absorbent material. Sweep up and shovel into waste drums. Wash the spillage area with water. Washings must be prevented from entering surface water drains. Waste disposal should be in accordance with existing Community,National and local regulations. For safety and environmental precautions, please review entire Material Safety Data Sheet for necessary information. 7. HANDLING AND STORAGE STORAGE TEMPERATURE HANDLING/STORAGE SENSITIVITY TO STATIC ELECTRICITY SENSITIVITY TO MECHANICAL IMPACT Ambient. Normal precautions for handling chemicals are applicable. No No 8. EXPOSURE CONTROLS/PERSONAL PROTECTION VENTILATION REQUIREMENTS EYE PROTECTION REQUIREMENTS General. Safety glasses, goggles or face shield to protect against splashing. PAGE 2 OF 6

19 PRODUCT NUMBER December-2008 GLOVE REQUIREMENTS The use of chemically resistant gloves is recommended. CLOTHING REQUIREMENTS Wear protective equipment to comply with good occupational hygiene practice. CHANGE/REMOVAL OF CLOTHING Remove contaminated clothing and launder before reuse. WASH REQUIREMENTS Wash before eating, drinking, or using toilet facilities. RESPIRATOR REQUIREMENTS Avoid prolonged or repeated breathing of vapor or mists. If exposure may or does exceed occupational exposure limits, use a NIOSH approved respirator to prevent overexposure. 9. PHYSICAL AND CHEMICAL PROPERTIES PURE SUBSTANCE OR MIXTURE Mixture PHYSICAL FORM Liquid COLOR Light yellow ODOR No ODOR THRESHOLD Not available PH AS IS OXIDIZING PROPERTIES Not applicable BOILING POINT > 230 C MELTING/FREEZING POINT Not applicable SOLUBILITY IN WATER Soluble PARTITION COEFFICIENT (n-octanol/water) Not applicable VISCOSITY Approximately 100 cps SPECIFIC GRAVITY (WATER=1) 1.13 EVAPORATION RATE 1 (Water = 1) VAPOR PRESSURE (mmhg) None Established VAPOR DENSITY (air = 1) None Established VOLATILES % Water VOLATILE ORGANIC COMPOUNDS Negligible AUTOIGNITION Not available FLASH POINT > 100 C 10. STABILITY AND REACTIVITY STABILITY HAZARDOUS DECOMPOSITION PRODUCTS Stable under normal temperature and pressure. Thermal decomposition may release toxic and/or hazardous gases. 11. TOXICOLOGICAL INFORMATION ROUTE OF ENTRY Inhalation; Ingestion; Skin Contact; Eye Contact CARCINOGEN COMPONENT There is no evidence that this product poses a carcinogenic risk under IARC (group) NTP OSHA Substance Specific Regulation PAGE 3 OF 6

20 PRODUCT NUMBER December-2008 normal conditions of handling and use. ACUTE (SHORT TERM) EFFECTS OF EXPOSURE CHRONIC (LONG TERM) EFFECTS OF EXPOSURE EFFECTS OF CHRONIC EXPOSURE Although this product has not been tested for chronic effects it is judged as having a low order of toxicity based on component information. Use of good industrial hygiene practices is recommended. TARGET ORGANS Not applicable. 12. ECOLOGICAL INFORMATION POTENTIAL TO BIOACCUMULATE AQUATIC TOXICITY Unknown. None Established 13. DISPOSAL CONSIDERATIONS WASTE DISPOSAL METHODS Waste disposal should be in accordance with existing Community,National and local regulations. EMPTY CONTAINER WARNINGS Empty containers may contain product residue; follow MSDS and label warnings even after they have been emptied. 14. TRANSPORTATION INFORMATION This section provided for general information only. The shipping description below may not represent requirements for all modes of transportation, packaging, shipping methods or locations outside of the United States. FOR MORE COMPLETE TRANSPORTATION REGULATORY INFORMATION PLEASE REFER TO THE SHIPPING DOCUMENTS ACCOMPANYING THE SHIPMENT OF THIS PRODUCT. DOT CLASSIFICATION PROPER SHIPPING NAME NOT APPLICABLE The information provided herein may not include the impact of additional regulatory requirements (eg, for materials meeting the definition of a hazardous waste under RCRA, hazardous substances under CERCLA, and/of marine pollutants under CWA or other similar federal, state or local laws) or any associated exceptions or exemptions under regulations applicable to the transport of this material. 15. REGULATORY INFORMATION PAGE 4 OF 6

21 PRODUCT NUMBER USA TSCA 15-December-2008 This material is not on the TSCA Inventory. It is excluded under the Food, Drug, and Cosmetic Act. SARA - Section 313 (Superfund Amendments and Reauthorization Act of CFR 372) CAS NUMBER Contains no substances at or above the reporting threshold under Section 313. CONCENTRATION (% by weight) CALIFORNIA PROPOSITION 65 WARNING: This product contains the following chemicals that are known to the State of California to cause cancer, birth defects or other reproductive harm. Unless a concentration is specified in Section 2 of the MSDS, the below chemical/s are present in trace amounts. COMPONENT CAS NUMBER None reportable. 16. OTHER INFORMATION HMIS Hazard Ratings HMIS ratings are based on a 0-4 rating scale, with 0 representing minimal hazards or risks, and 4 representing significant hazards or risks. Although HMIS ratings are not required on MSDSs by OSHA's 29 CFR , we choose to provide them as a service to our customers using HMIS. These ratings are to be used only with a fully implemented HMIS program. To deal adequately with the safe handling of this material, all the information contained in this MSDS must be considered. NPCA recommends that employers must determine appropriate PPE for the actual conditions under which this product is used in their workplace. For information on PPE codes, consult the HMIS Implementation Manual. When two ratings are provided for Health, the first represents the material 'as supplied', and the second represents the material 'in use'. * = chronic health hazard HMIS is a registered trademark of the National Paint and Coatings Association (NPCA). Health Flammability Reactivity MSDS DATE FOR INFORMATION CONTACT: 15-December-2008 Akzo Nobel Surface Chemistry LLC Phone: ADDITIONAL INFORMATION: The information given and the recommendations made herein apply to our product(s) alone and are not combined with other product(s). Such are based on our research and on data from other reliable sources and are believed to be accurate. No guaranty of accuracy is made. It is the purchaser's PAGE 5 OF 6

22 PRODUCT NUMBER December-2008 responsibility before using any product to verify this data under their own operating conditions and to determine whether the product is suitable for their purposes. PAGE 6 OF 6

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