LiceAway 100% MADE IN ITALY

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1 LiceAway Medical Device based on natural active principles suitable for the treatment and the eradication of head lice, larvae and nits on hair and scalp. 100% NATURAL PRODUCT MADE IN ITALY

2 Head Lice infestation (pediculosis) is still a major problem especially in schools n Infested People The number of cases has increased worldwide since the mid-1960s, reaching hundreds of millions annually. (1) About 6-12 million children between the ages of 3 and 11 are treated annually for head lice in the United States alone. (2) High levels of louse infestations have also been reported from all over the world including the most civilized European countries. (3,4) LiceAway Head lice infestation is a cause of some concern in public health; because although head lice are not carriers of other infectious diseases, it bites the skin causing itching and rash that may extend well down the back of the neck. (5) LICE AWAY Kit allows with only few treatments the complete lice and egg s elimination from the head in a full natural way, respecting hair and scalp s tropism.

3 The main product is the lotion Lice Away Spray, designed to eradicate human lice on the head (Pediculus humanus capitis). Having been made entirely of natural extracts is to be considered as just one more advantage of many which the product LICE AWAY SPRAY has over the rest of the competitors products available on the market containing synthetic chemical antiparastic (Permethrin, Tetrametrine, and Phenothrin) which are toxic for the human neural membranes or they are based on organ phosphorus pesticides (Malathion). The lotion is a new oil-based product, which contains coconut oil, anise essential oil and essential oil of ylang-ylang. These natural components have been selected for their high efficacy and synergy in treating human pediculosis, something already well known in the literature. (6-11) The anti-parasitic action provided by the coconut oil is not chemical but physical and it is possible because of its molecular ability to form a film around the lice and the nits. That leads to a surrounding and immobilizing effect, which provokes respiratory difficulties and suffocating because it breathes from the back and uses its beak to get stuck with to the hair and sucking blood. The same mechanism of action is identical for the rest of the essential oils included in the formula. The pediculicide action is accomplished by the oil of anise (Pinpinella anisum), which favorable effect has been demonstrated and described in numerous international studies. The essential oil of anise and ylang ylang, with their low molecular weight monoterpenic compounds, penetrate to the cuticle coating of the parasite, occluding the pores of its respiratory system and consequently causing the its death by suffocating it. The product has physical effect rather than chemical, which disables the louse to develop any resistance. That is the reason why Lice Away can be used over and over again. (12) LICE AWAY works always in a SAFE and DEFINITIVE way, as shown by the clinical efficacy trials carried on the products over some formations and market leader products. (13) % Knock down at 15 minutes a 15 min % Lice Away 96,70% Market Leader product 63,50% Dimeticonbased Formula Product 0% Emulsionbased Formula (12) % Knock Down 15 min Lice Away 100% Market Leader product 96,70% Dimeticon- based Formula 63,50% Emulsion- based Formula 0%

4 LiceAway Kit Medical Device based on natural active principles suitable for the treatment and the eradication of head lice, larvae and nits on hair and scalp. LICE AWAY Spray: innovative into the package too! The lotion is available in a new 100 ml can which is designed following a new technology called bag-on-valve (BOV); this technology doesn t use chemical propellants or gas for the distribution of the content; the distribution itself results from compressed air which could be found in the bag inside the can. This method allows the product to be released in optimal dose and, thanks to the innovative spray nozzle, the flow gets through the hair in a direct way down to its inner layer. Thus the product doesn t only wet the hair, as it often happens, but it really reaches the depth of the scalp INNOVATIVE BOV TECHNOLOGY LICE AWAY Shampoo has a new formula specifically developed to fulfill three functions: The first, most obvious, to remove the product distributed on the hair, which being based on oils, requires suitable degreasing agents; The second function is to facilitate (thanks to its components) the separation of the nits (lice eggs) from the hair; Finally, the shampoo has been enriched with natural oilextracts such as Thyme, Rosemary, Lavender and Turkish Rose which in addition to the pleasant scent they have, they produce an unfavorable environment.

5 LiceAway Kit Medical Device based on natural active principles suitable for the treatment and the eradication of head lice, larvae and nits on hair and scalp. Simple and detailed INSTRUCTIONS. More, the package contains an illustrated leaflet about Head Pediculosis, making you fully understand the pathology and its correct treatment. LICE AWAY Plastic Magnifying Lens Is large, easy and comfortable to use. It makes possible and easier the detection of the presence of parasites or nits on the head. LICE AWAY Comb has a large handle with long steel teeth. The teeth have an innovative shape with attaching function which has been studied purposely. Their main function is to keep the lice on the comb while its running easily through the hair. The edges of the teeth are rounded so they do not hurt in any way the scalp.

6 LiceAway Medical Device based on natural active principles suitable for the treatment and the eradication of head lice, larvae and nits on hair and scalp. If you ONLY suspect the presence of lice LICE AWAY can be used safely without any toxic effect. BIBLIOGRAPHY 1. Norman G. Gratz (1998). Human lice: Their prevalence, control and resistance to insecticides. A review (PDF). Geneva, Switzerland: World Health Organization. Retrieved Division of Parasitic Diseases (DPD), National Center for Zoonotic, Vector-Borne, and Enteric Diseases (ZVED) (May 16, 2008). Head lice fact sheet. Centers for Disease Control and Prevention website. Atlanta, GA: Department of Health and Human Services, US Government. Retrieved 28 May Mumcuoglu, Kosta Y.; Barker CS, Burgess IF, Combescot- Lang C, Dagleish RC, Larsen KS, Miller J, Roberts RJ, Taylan- Ozkan A. (2007). International Guidelines for Effective Control of Head Louse Infestations. Journal of Drugs in Dermatology 6 (4): PMID Ian Burgess (2004). Human Lice and their Control. Annual Review of Entomology (Annual Reviews) 49: doi: /annurev.ento PMID Rozsa, Lajos; Apari P. (2012). Why infest the loved ones inherent human behaviour indicates former mutualism with head lice. Parasitology 139 (6): in press. 6. Mumcuoglu, K.Y., J. Miller, C. Zamir, G. Zentner, V. Helbin & A. Ingber The in vivo pediculicidal efficacy of a natural remedy. Isr. Med. Assoc. J. 4: Mumcuoglu, K.Y Prevention and treatment of head lice in children. Pediatric Drugs 1: Burgess IF, Brunton ER, Burgess NA. Clinical trial showing superiority of a coconut and anise spray over permethrin 0.43% lotion for head louse infestation, ISRCTN Eur J Pediatr 2010; 169: Connolly M, Stafford KA, Coles GC, Kennedy CT, Downs AM. Control of head lice with a coconut-derived emulsion shampoo. Eur Acad Dermatol Venereol 2009; 23: Canyon DV, Speare R. A comparison of botanical and synthetic substances commonly used to prevent head lice (Pediculus humanus var. capitis) infestation. Int J Dermatol Apr;46(4): Asenov A, Oliveira FA, Speare R, Liesenfeld O, Hengge UR, Heukelbach J. Efficacy of chemical and botanical overthe-counter pediculicides available in Brazil, and off-label treatments, against head lice ex vivo. Int J Dermatol Mar;49(3): doi: /j x. 12. Terri L. Meinking, BA; Lidia Serrano; Bruce Hard, MA; Pamela Entzel, JD, MPH; Glendene Lemard, MA; Elisabeth Rivera; Maria Elena Villar, MPH Comparative In Vitro Pediculicidal Efficacy of Treatments in a Resistant Head Lice Population in the United States Arch Dermatol. 2002;138(2): doi: /archderm Entostudio Efficacy Studies of Head lice infestation s Spray formulations Data on file 100% NATURAL PRODUCT MADE IN ITALY

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