.DEFY LINES. O N YO U R FA C E. Actual patient. Results may vary. P rovides natural-looking results. L asts up to 1 year with optimal treatment

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1 (.DEFY LINES. PA R E N T H E S E S H AV E N O P L A C E O N YO U R FA C E. ) Actual patiet. Results may vary. I statly smooths away the deeper lies alog the sides of your ose ad mouth P rovides atural-lookig results L asts up to 1 year with optimal treatmet APPROVED USE JUVÉDERM XC ijectable gel is for ijectio ito areas of facial tissue where moderate to severe facial wrikles ad folds occur to temporarily add volume to the ski, especially aroud the ose ad mouth. IMPORTANT SAFETY INFORMATION Are there ay reasos why I should ot receive JUVÉDERM XC? Do ot use the product if you have severe allergies with a history of severe allergic reactios (aaphylaxis), or if you are allergic to lidocaie or the proteis (grampositive bacterial proteis) used to make the hyaluroic acid (HA) i JUVÉDERM XC. Please see additioal Importat Safety Iformatio iside JVD Defy patiet Bro_ST.idd 1 7/24/14 11:46 A

2 YOUR SKIN CHANGES OVER TIME As you age, your ski loses elasticity ad moisture. This ormal agig process, plus evirometal factors like su exposure, cause differet facial lies to form, icludig moderate to severe wrikles ad folds. There are several differet types of facial lies that form aroud your ose ad mouth. These iclude the paretheses lies, vertical lip lies, corer lies, ad marioette lies. As you age, these lies may become more oticeable. Paretheses Lies Vertical Lip Lies Corer Lies Marioette Lies YOUTHFUL FACE: Smooth AGING FACE: Wrikles ad lies JVD Defy patiet Bro_ST.idd 2-3 My ier impressio of myself ad my outer appearace did't match. 7/24/14 11:47 AM

3 LEARN HOW TO DEFY LINES AND GET NATURAL-LOOKING RESULTS HOW IT WORKS JUVÉDERM XC ijectable gel: Is a osurgical treatmet Cotais a modified hyaluroic acid, derived from a aturally occurrig sugar foud i the huma body Is getly ijected by your healthcare professioal uder the ski usig a fie eedle Cotais a commo aesthetic called lidocaie to reduce discomfort JUVÉDERM XC is a osurgical filler your healthcare professioal uses to istatly smooth away the deeper lies alog the sides of your ose ad mouth. Get atural-lookig results for up to 1 year with optimal treatmet. Idividual results may vary. Actual patiet. Results may vary. Everyoe will otice, o oe will kow. Shaw See the full gallery of JUVÉDERM XC before-ad-after photos at Juvederm.com. IMPORTANT SAFETY INFORMATION (cotiued) What precautios should my doctor advise me about? The safety of JUVÉDERM XC ijectable gel for use durig pregacy, i wome who are breastfeedig, or i patiets with very thi ski i the cheek area has ot bee studied JVD Defy patiet Bro_ST.idd 4-5 IMPORTANT SAFETY INFORMATION (cotiued) The safety for use i patiets uder 18 years has ot bee studied The safety ad effectiveess for treatmet i areas other tha facial wrikles ad folds (such as lips) have ot bee established Please see additioal Importat Safety Iformatio o followig pages. 7/24/14 11:47 AM

4 SEE THE DIFFERENCE WITH JUVÉDERM XC TALK TO YOUR HEALTHCARE PROFESSIONAL TO SEE IF JUVÉDERM XC IS RIGHT FOR YOU. ABBEY LIZETTE Idividual results may vary. Idividual results may vary. Uretouched photos of paid model take before treatmet ad 2 weeks after treatmet. A total of 3.2 ml of JUVÉDERM XC was ijected ito the paretheses lies, corer lies, ad marioette lies. These photos are ot of a cliical trial subject. Uretouched photos of paid model take before treatmet ad 2 weeks after treatmet. A total of 2.0 ml of JUVÉDERM XC was ijected ito the paretheses lies, corer lies, ad marioette lies. These photos are ot of a cliical trial subject. LAURA JENNIFER Idividual results may vary. Idividual results may vary. Uretouched photos of paid model take before treatmet ad 2 weeks after treatmet. A total of 3.0 ml of JUVÉDERM XC was ijected ito the paretheses lies, corer lies, marioette lies, ad vertical lip lies. These photos are ot of a cliical trial subject. IMPORTANT SAFETY INFORMATION (cotiued) The safety for use i patiets with a history of excessive scarrig or pigmetatio disorders has ot bee studied ad may result i additioal scars or chages i pigmetatio Tell your doctor if you are o therapy used to decrease the body s immue respose (immuosuppressive therapy). Use may result i a icreased risk of ifectio JVD Defy patiet Bro_ST.idd 6-7 Uretouched photos of paid model take before treatmet ad 2 weeks after treatmet. A total of 4.2 ml of JUVÉDERM XC was ijected ito the paretheses lies, corer lies, marioette lies, ad vertical lip lies. These photos are ot of a cliical trial subject. IMPORTANT SAFETY INFORMATION (cotiued) Tell your doctor if you are usig medicatios that ca prolog bleedig, such as aspiri, ibuprofe, or other blood thiers; as with ay ijectio, this may result i icreased bruisig or bleedig at the ijectio site Please see additioal Importat Safety Iformatio o followig pages. 7/24/14 11:47 AM

5 LONG-LASTING RESULTS UP TO 1 YEAR The treatmet was quick, ad it did't feel like a big deal at all. The first ad oly ijectable gel for wrikles ad folds that s FDA approved to last up to 1 year with optimal treatmet. LISA PG 7 Fold Out The results, o the other had, are a big deal to me. PG 12 B/C EMILY Idividual results may vary. 6 WEEKS Uretouched photos of paid JUVÉDERM XC ijectable gel patiet who received a 3-syrige treatmet to correct paretheses lies. Oe syrige = 1.0 ml of JUVÉDERM XC. 1 YEAR TREATMENT I cliical studies, optimal correctio was achieved with 3.2 ml. Results lasted up to 1 year. These photos are ot of a cliical trial subject. PG 1 F/C Idividual results may vary. Uretouched photos of paid JUVÉDERM XC ijectable gel patiet who received a 3-syrige treatmet to correct paretheses lies. Oe syrige = 1.0 ml of JUVÉDERM XC. JUVÉDERM XC is the # 1 sellig filler i the US 6 WEEKS 1 YEAR TREATMENT I cliical studies, optimal correctio was achieved with 3.2 ml. Results lasted up to 1 year. These photos are ot of a cliical trial subject. IMPORTANT SAFETY INFORMATION (cotiued) If laser treatmet, chemical peel, or ay other procedure based o active dermal respose is cosidered after treatmet, or if the product is admiistered before the ski has healed completely, there is a possible risk of a iflammatory reactio at the treatmet site As with all ski ijectio procedures there is a risk of ifectio 37/8 It's your time to defy. 4 4 Please see additioal Importat Safety Iformatio o back page JVD Defy patiet Bro_ST.idd /24/14 11:48 AM

6 Visualize the differece for yourself with JUVÉDERM XC DOWNLOAD THE JUVÉDERM XC TREATMENT VISUALIZER APP. * The JUVÉDERM XC Treatmet Visualizer app is available for all Apple devices, as well as the Adroid smartphoe. *The JUVÉDERM XC Treatmet Visualizer app is for illustrative ad demostrative purposes oly. The results displayed may ot reflect actual results. IMPORTANT SAFETY INFORMATION (cotiued) What are possible side effects? The most commoly reported side effects for JUVÉDERM XC ijectable gel were temporary ijectio-site redess, swellig, pai/tederess, firmess, lumps/ bumps, bruisig, itchig, ad discoloratio. They were predomiatly mild or moderate i ature ad lasted 7 days or less. To report a problem with JUVÉDERM XC, please call Allerga Product Surveillace at For more iformatio, please see the About Safety page at or call the Allerga Medical Iformatio lie at JUVÉDERM XC ijectable gel is available by prescriptio oly. Ask your healthcare professioal if JUVÉDERM XC is right for you Allerga, Ic. ad marks owed by Allerga, Ic. JUVÉDERM mark owed by Allerga Idustrie, SAS. Adroid is a trademark of Google Ic. Re-order: APC37NC JVD Defy patiet Bro_ST.idd 12 7/24/14 11:48 A