Therapeutic Solutions for Healthier Skin

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1 Therapeutic Solutions for Healthier Skin ZO Skin Health, Inc. is the only resource for comprehensive therapeutic and aesthetic skincare solutions. Based on more than 35 years of proven innovation in skincare, Dr. Zein Obagi has developed the ZO Skin Health Circle paradigm. This concept bridges the gap between therapeutic and daily skincare by providing the most effective technology and products to achieve continuously healthy skin. Visit to learn more about how ZO Skin Health, Inc. can help you experience healthy skin every day ZO Skin Health, Inc. and Dr. Obagi have no business relationship with Obagi Medical Products, and Obagi Medical Products does not sell or endorse using any ZO product. ZO is a registered trademark of ZO Skin Health, Inc

2 Solutions that Create Healthy Skin ZO Skin Health Circle Comprehensive & Continuous Solutions For over three decades, Dr. Zein Obagi defined the concept of skin health and developed skincare treatments and programs that can create truly healthy skin. Now with the introduction of ZO Medical products, Dr. Obagi s next generation of therapeutic skincare products and treatments are exclusively available through skin health professionals. Advanced Skin Health Solutions Under the guidance of Dr. Zein Obagi, ZO Skin Health, Inc. has developed a wide spectrum of therapeutic treatment protocols for everyone regardless of skin condition, age, gender or ethnicity. Based on the latest advances in skin therapy technology biotechnology complexes, plant stem cell components, and multi-therapy delivery systems these products and programs have been optimized for your specific needs. ZO Skin Health Circle The ZO Skin Health Circle concept, developed by Zein Obagi, MD, provides comprehensive and continuous solutions to achieve healthy skin for life. ZO Medical: Therapeutic Solutions Products, protocols, and treatments provided by skincare professionals for a wide range of skin disorders and chronic conditions. ZO Skin Health: Daily and Preventive Skincare A comprehensive array of products maintain the results of therapeutic treatments and support daily skin health and protection from the environment. The ZO Definition of Healthy Skin Smooth Strong Firm Even-toned Hydrated Disease-free

3 ZO Medical Products OILACLEANSE Cleanser for Normal to Oily Skin Dual-action cleanser exfoliates and cleanses skin targeting excess oil. Removes oil and other impurities to clean the skin and help clear acne. Reduces the factors that contribute to skin irritation Helps decrease the level of bacteria on skin surface Promotes exfoliation 240 ml / 8 Fl. Oz. NORMACLEANSE Cleanser for Normal to Dry Skin Its advanced surfactant gently removes impurities and oil, and prepares the skin to receive therapeutic treatments. This unique formulation gently cleans and conditions the skin. Highly advanced surfactant matrix removes impurities Peptide and collagen-boosting complex helps firm the skin Moisturizing complex nourishes and calms the skin 240 ml / 8 Fl. Oz. FOAMACLEANSE Gentle Foaming Cleanser for All Skin Types Formulated for all skin types, this gentle foaming cleanser is designed to remove impurities, deep clean pores and leave the skin feeling refreshed, clean and hydrated. Glycerin assists with hydration and helps to replenish moisture Spiraea ulmaria extract (meadowsweet) helps to calm inflammatory skin conditions Camellia sinensis leaf extract (green tea) provides potent antioxidant benefits to fight free radicals BALATONE Calming Toner ph Balancer This unique toner optimizes the penetration of therapeutic treatments by removing impurities and balancing the ph of weak skin. It invigorates dry, sensitive and irritated skin with its proprietary technology. Unique combination of solvents, astringents, and exfoliants thoroughly clears and cleanses the skin Exclusive blend of conditioners, moisturizers and hydrators soothes treated skin Gentle cooling action adds comfort to reduce irritation 180 ml / 6 Fl. Oz. VITASCRUB Invigorating Foaming Scrub An invigorating foaming scrub that sweeps away excess oil, dirt and impurities leaving skin feeling smooth, refreshed and clean. Helps improve circulation and restores skin s natural glow. Dual exfoliation process removes dead skin cells, whiteheads and blackheads Exclusive 12-hour multi-oxidant time-release complex helps provide continuous antioxidant benefits Skin re-hydrators ensure skin remains soft and moist Net Wt. 113 g / 4 Oz. 240 ml / 8 Fl. Oz.

4 ZO Medical Products CEBATROL Oil Control Pads An invigorating acne medication to treat and prevent outbreaks. Its proven exfoliants effectively remove dead skin cells. These pads also contain an emollient complex to help soothe skin and reduce redness. Three proven exfoliants salicylic acid, mandelic acid and glycolic acid Botanical extracts blend provides antioxidant benefits and anti-irritant properties to soothe skin and reduce redness Urea helps restore moisture and hydration Texture of pads specifically designed to help promote exfoliation 60 Pads, 75 ml / 2.5 Fl. Oz. BRIGHTENEX Skin Brightener & Correcting Crème Non-Hydroquinone This multi-action formula rapidly brightens and evens skin tone quality, and can be used as a first course in treating hyperpigmentation and/or as a maintenance product after completing a course of Rx treatment. Minimizes skin redness caused by environmental factors and helps prevent future damage. High-potency retinol in an oleosome delivery system works immediately on contact Proven natural amino compound helps brighten and even skin tone Natural soybean antioxidant containing phospholipids helps minimize uneven color 75 ml / 2.5 Fl. Oz. AKNETROL Acne Treatment Benzoyl Peroxide 10% This maximum strength acne fighting formula helps minimize surface oil, minimize redness and prevent future breakouts. An increase in cellular turnover promotes exfoliation to decrease the spread of bacteria and clear clogged pores. Tea tree oil provides additional properties to attack surface bacteria Glycerin helps restore moisture and hydration Botanical extract blend provides maximum antioxidant benefits 60 ml / 2 Fl. Oz. RETAMAX Active Vitamin A Micro Emulsion Utilizing an innovative micro emulsion technology, this potent retinol formula, blended with plant stem cell antioxidants and biomimetic proteins, helps reverse the signs of aging and aids in the prevention of future skin damage. Aids in restoration of texture, strength and firmness High-potency vitamin A stimulates the skin s natural rebuilding process Vitamins C and E, and buddleja plant stem cells provide antioxidant and anti-irritation action Micro emulsion technology supports rapid delivery of key ingredients Helps improve skin color, texture and tone 75 ml / 2.5 Fl. Oz.

5 ZO Medical Products GLYCOGENT Exfoliation Accelerator An innovative exfoliation accelerator engineered to help reduce irritation and prevent future damage. Active ingredients enhance mitosis and help correct skin discoloration. Potent glycolic and lactic acid complex provides skin surface renewal Anti-redness properties help minimize the appearance of irritated skin Proven antioxidants help prevent future skin damage 75 ml / 2.5 Fl. Oz. RESTORACALM Soothing Recovery Crème Formulated to help reduce redness, calm skin irritation and stimulate natural skin barrier restoration. It provides immediate comfort and hydration, for sensitive, weak or compromised skin. Buddleja plant stem cell technology acts as a potent antioxidant Skin calming beta-glucan soothes and provides rapid relief, reducing the appearance of skin redness and flakiness Silk serecin protein biotechnology supports skin s natural recovery process and helps protect from sun induced damage 50 ml / 1.7 Fl. Oz. INVISAPEEL Intensive Resurfacing Peel This formulation uses an enzymatic process to renew the epidermis, leaving skin noticeably smoother, firmer and brighter. Provides enhanced exfoliation of the epidermis without any apparent flaking or peeling Specialized enzymes accelerate the reduction of the appearance of discoloration, rough texture and dehydrated skin Skin is able to receive benefits from additional ZO Medical products 50 ml / 1.7 Fl. Oz. HYDRAFIRM Eye Brightening Repair Crème Specially designed to help reverse the appearance of aging skin around the delicate eye area. Instantly helps smooth, firm and reduce the appearance of dark circles and puffiness. Retinol and biomimetic proteins help tighten and diminish the appearance of fine lines and wrinkles Rapidly stimulates circulation to reduce the signs of puffiness Proprietary plant stem cell blend provides potent antioxidant benefits to protect the delicate eye area from future signs of aging Net Wt. 15 g / 0.5 Oz.

6 ZO Medical Products ZO Prescription Products Highly potent medical products to repair your skin. (prescription required) LIPREBUILD Advanced Therapy Lip Treatment Bioengineered to reverse and restore severely dry, cracked and wrinkled lips using a clinically proven moisture recycling technology to plump lips, improving overall shape, size and contour while restoring lips to their natural rosy color. Powerful antioxidants help defend lips from continued exposure to the environment Soothes lips with a cooling complex For use with or without lip color Net Wt. 16 g / 0.56 Oz. MELAMIN Skin Bleaching & Correcting Crème Hydroquinone USP, 4% A highly effective Rx solution to lighten hyperpigmentation with 4% hydroquinone. This formulation alters the essential subcellular metabolic processes that cause cell damage. It inhibits melanin production to even skin color and tone. 4% hydroquinone acts as a gradual bleaching agent Reduces the appearance of chloasma, melasma, freckles and sun damage Vitamin E helps repair damaged skin cells Net Wt. 80 g / 2.8 Oz. (Rx Only) OCLIPSE-C Broad-Spectrum Sunscreen SPF 50 A lightweight natural mineral sunscreen that offers a daily multi-defense system with broad spectrum UVA/UVB protection. This innovative formulation shields skin from high energy blueviolet light that has been shown to induce premature aging and hyperpigmentation. Ideal for even the most sensitive skin types or anyone needing post-procedure protection. Melanin provides extended protection against environmental aggressors Potent antioxidants provide a second line of defense against cell damaging free radicals Helps inhibit skin redness from sun exposure Net Wt. 118 g / 4 Fl. Oz. MELAMIX Skin Lightener & Blending Crème Hydroquinone USP, 4% A 4% hydroquinone bleaching cream penetrates the skin and effectively delivers the active ingredients of the system to the melanocytes. It alters the essential subcellular metabolic processes that cause cell damage and inhibit melanin production. 4% hydroquinone acts as a gradual blending agent Reduces the appearance of chloasma, melasma and freckles Optimizes delivery of active ingredients Net Wt. 80 g / 2.8 Oz. (Rx Only) TRETINOIN Tretinoin USP available in 0.1% and 0.05% cream in 20 g tubes. Net Wt. 20 g (Rx Only)

7 ZO Medical Systems ZO MULTI-THERAPY HYDROQUINONE SYSTEM Designed by Zein Obagi, MD to treat several skin conditions. Main indications: Hyperpigmentation Treat moderate to severe hyperpigmentation, especially melasma. Recommended as a starting point for treating melasma. Severe Texture Damage Treat severely dry, dull, rough and leathery textured skin to help soften skin and restore a smooth, healthy glow. Sun Damage Treat severely dry, dull, leathery textures with visible sun spots and damage. Pre/Post Procedure Skin Conditioning Start on this system 4-6 weeks before office procedures, and use for 12 weeks afterwards for improved patient outcomes and longer lasting results. General Skin Health Restoration Use this system to improve the overall quality, health and appearance of the skin. MELAMIN Skin Bleaching & Correcting Crème (Hydroquinone USP, 4%) Net Wt. 32 g / 1.12 Oz. GLYCOGENT Exfoliation Accelerator (10% Concentration) MELAMIX Skin Lightener & Blending Crème (Hydroquinone USP, 4%) Net Wt. 32 g / 1.12 Oz. OSSENTIAL Daily Power Defense OCLIPSE-C Broad-Spectrum Sunscreen SPF 50 Net Wt. 60 g / 2 Oz. ZO NON-HYDROQUINONE HYPERPIGMENTATION SYSTEM Designed by Zein Obagi, MD for the treatment of hyper-pigmentation without the use of hydroquinone. Ideal for the treatment of skin conditions either when hydroquinone treatment is completed or contraindicated, or as a healthy maintenance system Use after completing a course of hydroquinone for 4-5 months Use when skin bleaching is not desired Use when even color tone is the objective Use when texture and anti-aging benefits are part of restoring even color tone BRIGHTENEX Skin Brightener & Correcting Crème (Non-Hydroquinone) RESTORACALM Soothing Recovery Crème RETAMAX Active Vitamin A Micro Emulsion OSSENTIAL Daily Power Defense OCLIPSE-C Broad-Spectrum Sunscreen SPF 50 Net Wt. 60 g / 2 Oz.

8 ZO GSR Systems ZO GSR SYSTEM Normal to Oily The ZO GSR: Getting Skin Ready system will optimize the effectiveness of your ZO treatment program and is the first step in your protocol. This basic system includes three products; a cleanser, a scrub, and oil control pads. Step 1 Cleanse Cleanse your face twice a day to remove impurities, and refresh and revive skin. Step 2 Scrub Scrub your skin 2-3 times a week to remove buildup and activate skin cells Step 3 Oil Control Oil Control is one of the best ways to fight aging, breakouts, and keep skin healthy and vital. FOAMACLEANSE Gentle Foaming Cleanser for All Skin Types 60 ml / 2 Fl. Oz. VITASCRUB Invigorating Foaming Scrub Net Wt g / 2 Oz. CEBATROL Oil Control Pads 60 Pads ZO GSR SYSTEM Normal to Dry The ZO GSR: Getting Skin Ready System will optimize the effectiveness of your ZO treatment program and is the first step in your protocol. This basic system includes products to cleanse, scrub, and tone skin. Step 1 Cleanse Cleanse your face twice a day to remove impurities, and refresh and revive skin. Step 2 Scrub Scrub your skin 2-3 times a week to remove buildup and activate skin cells Step 3 Tone Oil removal is one of the best ways to fight aging, breakouts, and keep skin healthy and vital. NORMACLEANSE Cleanser for Normal to Dry Skin 60 ml / 2 Fl. Oz. OFFECTS Exfoliating Polish Net Wt. 65 g / 2 Oz. BALATONE Calming Toner, ph Balancer 60 ml / 2 Fl. Oz.

9 ZO Professional Peels Dr. Obagi s signature chemical peels rejuvenate your skin. (in-office medical treatments) ZO 3-STEP PEEL (Professional Use Only) This 3-Step Peel, designed by Zein Obagi MD, will reveal brighter, smoother, and tighter looking skin with minimal downtime and only mild peeling for up to 5 days. This peel is safe and suitable for any skin type or color. Visible improvement is seen with one treatment; however, a series of treatments can be repeated every 3-4 weeks for deeper repair. This unique peel not only works to exfoliate dead skin cells on the outer surface of the skin, but also works in the deeper layers to boost collagen production, improve elasticity, diminish lines and wrinkles, and reduce irregular skin pigmentation. Lastly, it works to restore hydration, enhance the skin s protective barrier and prevent future damage. Step 1 Peel Solution 17% salicylic acid, 10% trichloracetic acid, 5% lactic acid Step 2 Retinol Crème 6% retinol Step 3 Calming Crème Post Procedure Skin Relief For the improvement of: Fine lines and wrinkles Firmness and elasticity Irregular skin pigmentation Dull or rough skin texture Sun damaged skin, sunspots, dark patches Acne or acne scars ZO CONTROLLED DEPTH PEEL (Professional Use Only) This advanced peel resurfaces the skin at a deeper level. It is designed to tighten and regenerate the skin while dramatically improving the appearance of deeper lines and wrinkles, irregular skin pigmentation including melasma, and smooth skin s texture, including scars. For optimal results, condition the skin 6 weeks prior to the peel following the ZO Multi-Therapy Hydroquinone System. This peel uses trichloracetic acid (TCA) mixed with a base that allows your provider to tailor the depth of the peel to treat your specific skin condition. Peeling, redness, and irritation are normal and can last up to 7-10 days. This peel is suitable for most skin types and colors. Dramatic results will be seen with one treatment, but some patients require 2-3 peels repeated every 2-3 months for maximum benefits. For the improvement of: Deep lines and wrinkles Firmness and elasticity Melasma (epidermal and dermal) Rough uneven texture (large pores and scars) Photodamage (elastosis, lentigo, actinic keratosis) Acne and acne scars

10 Your ZO Medical Skincare Program With the guidance of your physician, the following skincare regimen is tailored to your specific skin condition and skin health goals. STEP PRODUCT DOSAGE/NOTES OILACLEANSE am / pm /week NORMACLEANSE am / pm /week FOAMACLEANSE am / pm /week BALATONE am / pm /week VITASCRUB am / pm /week CEBATROL am / pm /week AKNETROL am / pm /week BRIGHTENEX am / pm /week GLYCOGENT am / pm /week RETAMAX am / pm /week INVISAPEEL am / pm /week RESTORACALM am / pm /week HYDRAFIRM am / pm /week LIPREBUILD am / pm /week OCLIPSE-C am / pm /week MELAMIN (Rx Only) am / pm /week MELAMIX (Rx Only) am / pm /week TRETINOIN (Rx Only) am / pm /week ZO GSR SYSTEM (Normal to Oily) ZO GSR SYSTEM (Normal to Dry) ZO MULTI-THERAPY HYDROQUINONE SYSTEM (Rx Only) ZO NON-HYDROQUINONE HYPERPIGMETATION SYSTEM ZO 3-STEP PEEL (Professional Use Only) ZO CONTROLLED DEPTH PEEL (Professional Use Only) PHYSICIAN NAME DATE

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