STRUCTURISTE. Firming Lift Cream VOLUME I DENSITY I FIRMNESS. Re-establishes the original structures of the face

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1 STRUCTURISTE Firming Lift Cream Re-establishes the original structures of the face VOLUME I DENSITY I FIRMNESS

2 STRUCTURISTE TOTAL SKIN RESTRUCTURING FOR A SECOND YOUTH EFFECT From the age of 45, signs of skin slackening appear: the face loses its structure and the features sag. ATROPHIED FEATURES The skin loses its elasticity and the cheekbones, cheeks and chin lose their structure and become atrophied. EMACIATION OF THE TISSUES Facial contours lose volume, the cheeks become hollow, wrinkles are accentuated. FACIAL BLOATING A double chin appears. PHYTOMER, the anti-aging skincare expert, restores the face s triangle of youth with STRUCTURISTE Firming Lift Cream. Day after day, this biotechnological concentrate resculpts the facial contours by acting on three properties: VOLUME DENSITY FIRMNESS. A FORMULA WITH UNPRECEDENTED RESTRUCTURING PROPERTIES TOTAL SKIN REORGANIZING 1. EPS GMR, the new star EPS, harmonizes the skin structures to redefine the architecture of the face. TONE AND FIRMNESS OF THE SKIN 2. A duo of active ingredients expertly firms and tones the skin: - ECO-CHLORELLA, "the skin's architect" - EXTRACT OF MARSH TREFOIL, "the cell protector" RESCULPTED SKIN CONTOURS Immediately, the radiance of the complexion is enhanced. In one month, the face is visibly resculpted, reshaped and lifted. ULTRA-STRENGTHENING TOTAL COMFORT An ultra-comfortable reshaping cream with floral, green and musky notes.

3 A 360 BIOTECHNOLOGICAL FORMULA VOLUME DENSITY FIRMNESS PHYTOMER once again demonstrates anti-aging performance with its new EPS, a marine biotechnological star: EPS GMR Global Marine Reshaper. Its mission: 360 skin reorganization/restructuring at all skin layers. EPS GMR THE TOTAL SKIN REORGANIZER EPS GMR is synthesized naturally by a marine planktonic micro-organism collected in Guérande. This 100% biotechnological, cutting-edge active ingredient reorganizes the skin on three levels: 1. RESHAPING ACTION, by volumizing the dermis. 2. FIRMING ACTION, by solidifying the Dermal-Epidermal Junction (DEJ). 3. STRUCTURING ACTION, by restructuring the epidermis and the stratum corneum. 1/ RESHAPING ACTION: EPS GMR restores the density of the dermis 60 EPS GMR improves the support fiber network by increasing the synthesis of two key components in the dermal structure. - HYALURONIC ACID, the main component of the extracellular network: +23%* - HYALURONAN SYNTHASE 3 (HAS3), enzymes directly involved in hyaluronic acid synthesis: +49%* RESULT: the fiber network is restored and replenished. % of variation compared to untreated % + 23 % 0 HAS3 Hyaluronic Acid

4 EPS GMR encourages fibroblast mobility by increasing by 39%* the synthesis of a key receptor: the receptor CD44, responsible for the mobility of the fibroblasts on hyaluronic acid fibers. Fibroblast Schematization of the migration of a fibroblast along a hyaluronic acid fiber Receptor CD44 Hyaluronic acid fiber RESULT: the areas low in fibroblasts are repopulated. EPS GMR re-establishes the contractility of the dermis by increasing by 39%* the "firming" effect of the fibroblasts (seen on the pink surface). Untreated fibroblasts Fibroblasts treated with EPS GMR RESULT: the dermis is denser and more toned.

5 2/ FIRMING ACTION: EPS GMR reconnects the dermis to the epidermis via the Dermal-Epidermal Junction (DEJ) EPS GMR reinforces epidermal-dermal anchoring by increasing the synthesis of the anchoring proteins in the Dermal-Epidermal Junction (DEJ): Schematic representation of the Dermal-Epidermal junction (DEJ) - SYNDECAN: +40%*, protein that anchors the epidermis to the DEJ - COLLAGEN IV: +29%* and COLLAGEN VII: +117 %*, proteins that anchor the dermis to the DEJ RESULT: the dermis better performs its role of supporting the epidermis: skin sagging is checked. Syndecan Collagen IV Collagen VII EPIDERMIS DERMIS DEJ 3/ STRUCTURING ACTION: EPS GMR restores the upper layers of the skin EPS GMR improves cell cohesion in the epidermis and the stratum corneum by increasing the synthesis of the main components of the intercellular junctions. - In the epidermis, synthesis of the main component of the junctions between the keratinocytes: +122%* - In the stratum corneum, synthesis of the main component of the junctions between the corneocytes: +45%* RESULT: the epidermis is strengthened, the stratum corneum is reinforced. Dehydration is limited, skin is smoothed. FORMULATED WITH A DUO OF EXPERT INGREDIENTS FOR DOUBLE THE FIRMING EFFECTS ECO-CHLORELLA, "the skin's architect" Active ingredient from the green microalgae Chlorella Vulgaris. Stimulates the synthesis of structural proteins in the dermis and the DEJ. FOR MORE TONED SKIN EXTRACT OF MARSH TREFOIL, "the cell protector" Aquatic plant with powerful antioxidant properties. Fights against free radicals, thereby protecting vitamin C, vital in collagen maturation. FOR DENSER SKIN

6 STRUCTURISTE FULL VOLUME YET LIGHTWEIGHT A TOTAL COMFORT RESHAPING CREAM STRUCTURISTE Firming Lift Cream envelops the skin in an instant firming mesh and provides it with comfort that lasts all day long. AN AIRY TEXTURE WITH A DELICATE FLORAL SCENT An ultra-luscious cream with a soft, silky and powdery feel. Subtle musk, green and floral notes. REFERENCES Retail size: 50-ml jar - PFSVV109 Tester: 50-ml jar PSSVV109T Professional size: 100-ml tube - PFSVP109 Samples: 10 x 5-ml tube PFESV109

7 FACIAL STRUCTURES RE-ESTABLISHED IN 360 VOLUME DENSITY FIRMNESS INSTANT HYDRATION AND COMFORT - From the very first application MORE HYDRATION AND COMFORT +93 % hydration (0) Comfortable skin: 95% (1) IMPROVEMENT IN THE SKIN'S APPEARANCE Ultra-soft skin: 87% (1) Luminous skin: 79% (1) SKIN ARCHITECTURE REDEFINED - In one month RESCULPTED - RESHAPED CONTOURS The facial contours are redefined, as if lifted. Skin slackening is checked: Reduction in slackening of the facial contours up to 13% (2) observed in the areas represented in blue (facial contours, eyelids) FIRMER SKIN Improvement in skin firmness observed: More toned skin: 87% (3) Visibly firmer skin: 78% (3) Illustrations representing the best result obtained on 1 volunteer

8 PART OF A COMPREHENSIVE ANTI-AGING LINE DAY CREAM EARLY WRINKLES ESTABLISHED WRINKLES MATURE SKIN OVERALL ANTI-AGING SKIN SLACKENING INITIAL YOUTH Multi-Action Early Wrinkle Cream Multi-Action Early Wrinkle Fluid The 1 st anti-aging step to smooth and illuminate the skin. EXPERT YOUTH Wrinkle Correction Cream Total anti-aging correction to look younger in one month. OGÉNAGE EXCELLENCE Radiance Replenishing Cream The ultimate comforting skincare to restore density and regenerate fine to dry skin. PIONNIÈRE XMF Perfection Youth Cream The biotechnological innovation concentrate to smooth wrinkles in one hour. STRUCTURISTE Firming Lift Cream The cream with a shaping effect to re-establish the original structures of the skin. NIGHT CREAM TIRED SKIN NIGHT RECHARGE Youth Enhancing Cream The nighttime detox regimen to restore the skin's youth. PHYTOMER - 61 rue du Commandant l Herminier SAINT-MALO - FRANCE Tel.: +33 (0) Fax: +33 (0) phytomer@phytomer.com -

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