Accepted Manuscript. About melanocyte activation in idiopathic guttate hypomelanosis by 5-fluorouracil tattooing. Carlos Gustavo Wambier, MD, PhD

Size: px
Start display at page:

Download "Accepted Manuscript. About melanocyte activation in idiopathic guttate hypomelanosis by 5-fluorouracil tattooing. Carlos Gustavo Wambier, MD, PhD"

Transcription

1 Accepted Manuscript About melanocyte activation in idiopathic guttate hypomelanosis by 5-fluorouracil tattooing Carlos Gustavo Wambier, MD, PhD PII: S (18) DOI: /j.jaad Reference: YMJD To appear in: Journal of the American Academy of Dermatology Received Date: 2 March 2018 Revised Date: 25 May 2018 Accepted Date: 25 May 2018 Please cite this article as: Wambier CG, About melanocyte activation in idiopathic guttate hypomelanosis by 5-fluorouracil tattooing, Journal of the American Academy of Dermatology (2018), doi: / j.jaad This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

2 1 2 About melanocyte activation in idiopathic guttate hypomelanosis by 5-fluorouracil tattooing 3 Carlos Gustavo Wambier, MD, PhD, a a- Department of Medicine, State University of Ponta Grossa, Ponta Grossa, Brazil Corresponding author / Reprint requests: Prof. Carlos Gustavo Wambier, MD, PhD, Adjunct Professor of Dermatology, Department of Medicine, State University of Ponta Grossa. Address: Bloco M - Campus UEPG Uvaranas. Av. General Carlos Cavalcanti, 4748, Ponta Grossa, PR, Brazil. Phone: This article has no funding source. The authors have no conflict of interest to declare. Manuscript word count: 422 References: 3 Figures: 0

3 16 No abstract Key words: idiopathic guttate hypomelanosis; 5-fluorouracil; drug delivery; tattoo equipment; melanocytes Abbreviations and acronym list: FU: fluorouracil

4 To the Editor: I read with interest Arbache et al. s preliminary results of repigmentation of idiopathic guttate hypomelanosis in eight patients by 5-fluorouracil (FU) tattooing in a randomized, saline controlled, split-body trial. 1 As an enthusiast of the innovative technique of using professional tattoo machines as drug-delivery devices, 2,3 some comments are made necessary for better interpretation and reproduction of the trial. If the active drug is 5-FU, which was the origin and the concentration of 5-FU injectable solution used? After side randomization, which solution was performed first for each patient and were the needle cartridge and cup changed before starting the other side? Dilution of the 5-FU solution could occur if starting from the saline side, and cross-contamination of saline with 5-FU could occur if starting on the active drug side if performed with the same needles/cups. Curiously, three patients presented zero repigmentation in the saline side, two patients presented mild repigmentation ( %), but three patients presented high percentage of repigmentation ( %). Could the starting side explain these striking range of repigmentation results in the saline tattooing side? The article mentioned that two blinded dermatologists determined the limb with the best clinical outcome and that statistical analysis was performed by a photographic equipment software, however, the results only state 75.3% 5-FU repigmentation vs. 33.8% placebo, P<.001. Were these results from the clinical evaluation by the dermatologists (although their sum was over 100%) or were these results from repigmentation percentage derived from software inputs of colorimetry presented in the graph in Fig. 2, G and H? Nevertheless, the median of the results presented in the graph would be 75.8% for 5-FU repigmentation and 20.3% for saline, and the means 75% for 5-FU and 26.9% for saline, which differ from the results presented. Which statistic test was used?

5 About the conflicts of interests declared, no specific potential conflict of interest was disclosed, despite the statement that Dr Arbache s commercial involvement in this investigation was required ( ). Do authors directly profit from sales of tattoo machines, needle cartridges, drugs, or photographic equipment mentioned in the article? What is the relationship of the authors with Traderm? Is there any advantage for the dermatologic community to have tattoo machines and needles registered by trading companies as medical devices, since they have always been bought and used by lay art professionals? The active drugs and technique used are of primary importance: the difference between microneedling, ink tattooing, and drug tattooing. Finally, I hope that more attention is given by the dermatologic scientific community to the research of multiple applications of drug tattooing.

6 57 References: Arbache S, Roth D, Steiner D, Breunig J, Michalany NS, Arbache ST, et al. Activation of melanocytes in idiopathic guttate hypomelanosis after fluorouracil infusion using a tattoo machine: Preliminary analysis of a randomized, split-body, single blinded, placebo controlled clinical trial. J Am Acad Dermatol Jan;78(1): Wambier CG, Wambier SP de F, Pereira Soares MT, Breunig J, Cappel MA, Landau M. Therapeutic pearl: 5-fluorouracil tattoo for idiopathic guttate hypomelanosis. J Am Acad Dermatol Nov 1;9. 3. Wambier C. Dermatologic treatments with microinfusion of drugs into the skin with tattoo equipment: teaser series (abstract). J Am Acad Dermatol. 2018;78:[Poster 7834].

Intravenous Access and Injections Through Tattoos: Safety and Guidelines

Intravenous Access and Injections Through Tattoos: Safety and Guidelines CADTH RAPID RESPONSE REPORT: SUMMARY OF ABSTRACTS Intravenous Access and Injections Through Tattoos: Safety and Guidelines Service Line: Rapid Response Service Version: 1.0 Publication Date: August 03,

More information

*Resilient Hyaluronic Acid

*Resilient Hyaluronic Acid *Resilient Hyaluronic Acid TEOSYAL RHA* DYNAMIC AESTHETICS EXPAND YOUR POSSIBILITIES FACIAL REJUVENATION High patient expectations 1,2 / High medical standards 1,2 Natural results Immediate and long lasting

More information

Illuminating Medical Aesthetics: Shining a Light on Low-Level Light Therapy In the Medical Esthetic Practice. Sam Shatkin, MD

Illuminating Medical Aesthetics: Shining a Light on Low-Level Light Therapy In the Medical Esthetic Practice. Sam Shatkin, MD 24TH Annual Meeting Illuminating Medical Aesthetics: Shining a Light on Low-Level Light Therapy In the Medical Esthetic Practice Sam Shatkin, MD Upon completion of this presentation, the participants will

More information

PDF of Trial CTRI Website URL -

PDF of Trial CTRI Website URL - Clinical Trial Details (PDF Generation Date :- Tue, 02 Oct 2018 21:40:33 GMT) CTRI Number Last Modified On 26/12/2012 Post Graduate Thesis Type of Trial Type of Study Study Design Public Title of Study

More information

A novel daily moisturizing cream for effective management of mild to moderate Atopic Dermatitis in infants and children

A novel daily moisturizing cream for effective management of mild to moderate Atopic Dermatitis in infants and children TM Weber PhD 1, F Samarin MD 3, M Babcock MD 2, A Filbry PhD 4, C Arrowitz 1, F Rippke MD 4 1 Beiersdorf Inc., Wilton CT, USA 2 Mountaintop Dermatology, Colorado Springs CO, USA 3 Colorado Springs Dermatology

More information

Skin remodeling from the inside out CONSULTATION GUIDE

Skin remodeling from the inside out CONSULTATION GUIDE Skin remodeling from the inside out CONSULTATION GUIDE Achieve younger looking skin with Secret RF Secret RF microneedling is an innovative new aesthetic treatment that improves signs of aging skin including

More information

Laser Hair Removal: Results Of 2-Week Versus 6-Week Treatment Intervals

Laser Hair Removal: Results Of 2-Week Versus 6-Week Treatment Intervals Laser Hair Removal: Results Of 2-Week Versus 6-Week Treatment Intervals Jenifer R. Lloyd, D.O. Lloyd Dermatology and Laser Center Youngstown, Ohio Diane R. MacGillis, M.D. LCI Lasercom Clinics International

More information

CLINICAL EVALUATION OF REVIVOGEN TOPICAL FORMULA FOR TREATMENT OF MEN AND WOMEN WITH ANDROGENETIC ALOPECIA. A PILOT STUDY

CLINICAL EVALUATION OF REVIVOGEN TOPICAL FORMULA FOR TREATMENT OF MEN AND WOMEN WITH ANDROGENETIC ALOPECIA. A PILOT STUDY CLINICAL EVALUATION OF REVIVOGEN TOPICAL FORMULA FOR TREATMENT OF MEN AND WOMEN WITH ANDROGENETIC ALOPECIA. A PILOT STUDY Alex Khadavi, MD, et al,. Los Angeles, CA USA 2004 Abstract: This study was done

More information

PDF of Trial CTRI Website URL -

PDF of Trial CTRI Website URL - Clinical Trial Details (PDF Generation Date :- Fri, 21 Dec 2018 19:27:12 GMT) CTRI Number Last Modified On 06/01/2014 Post Graduate Thesis Type of Trial Type of Study Study Design Public Title of Study

More information

FACTS. about MemoryGel silicone gel-filled breast implants

FACTS. about MemoryGel silicone gel-filled breast implants FACTS about MemoryGel silicone gel-filled breast implants Are you considering breast implant surgery but not certain which type of implant to choose? YOU RE NOT ALONE. Science-based information to empower

More information

It is under the author s own responsibility

It is under the author s own responsibility Peter Bjerring, MD, PhD Medical Director and Head of The Laser Centre, Mølholm Hospital, Denmark Consultant, ZBC Multicare, Hilversum, Netherlands Professor, Faculty of Medicine, University of Swansea,

More information

Poster Department of Dermatology, Henry Ford Hospital, Detroit, MI; 2 Johnson & Johnson Consumer Inc., Skillman, NJ

Poster Department of Dermatology, Henry Ford Hospital, Detroit, MI; 2 Johnson & Johnson Consumer Inc., Skillman, NJ Poster 7237 A Single Center, Randomized, Double-Blinded, Multiple Exposure Evaluation of And SPF 100+ Sunscreens for Prevention of Erythema Under Actual Use Conditions Cynthia L. Nicholson MD 1, Indermeet

More information

Tolerance of a Low-Level Blue and Red Light Therapy Acne Mask in Acne Patients with Sensitive Skin

Tolerance of a Low-Level Blue and Red Light Therapy Acne Mask in Acne Patients with Sensitive Skin Poster 7098 Tolerance of a Low-Level Blue and Red Light Therapy Acne Mask in Acne Patients with Sensitive Skin Dara Miller 1, Michael J. Cohen 1, Adegboyega Adenaike 1, Julie Biron 2, Michael H. Gold,

More information

Autumn 2008 Circulation 25,000 PRSRT STD U.S. POSTAGE PAID PERMIT NO LONG BEACH, CA

Autumn 2008 Circulation 25,000   PRSRT STD U.S. POSTAGE PAID PERMIT NO LONG BEACH, CA Silk n from Home Skinovations (Yokneam, Israel) brings safe, effective hair reduction to the privacy of the home by harnessing a novel technology similar to intense pulsed light (IPL), in a small home-use

More information

Standardization of guidelines for patient photograph deidentification

Standardization of guidelines for patient photograph deidentification Boston University OpenBU BU Open Access Articles http://open.bu.edu MED: Otolaryngology Papers 2016-06-01 Standardization of guidelines for patient photograph deidentification Roberts, Erik Annals of Plastic

More information

Evaluation of Cosmeceutical Ingredients: What the Label May Not Reveal Patrick Bitter, MD. Regulation of Topical Skin Care Products.

Evaluation of Cosmeceutical Ingredients: What the Label May Not Reveal Patrick Bitter, MD. Regulation of Topical Skin Care Products. Evaluation of Cosmeceutical Ingredients: What the Label May Not Reveal Patrick Bitter, MD Regulation of Topical Skin Care Products US Food and Drug Administration (FDA) recognizes two categories of products

More information

DERMATOLOGISTS DEBUNK MYTHS, OFFER ADVICE FOR CONDITIONS THAT HIT BELOW THE BELT

DERMATOLOGISTS DEBUNK MYTHS, OFFER ADVICE FOR CONDITIONS THAT HIT BELOW THE BELT DERMATOLOGISTS DEBUNK MYTHS, OFFER ADVICE FOR CONDITIONS THAT HIT BELOW THE BELT NEW YORK (Nov. 13, 2008) While spider veins, varicose veins, cellulite and pedicures gone awry may sound like the makings

More information

Experience the Future of Hair Transplantation

Experience the Future of Hair Transplantation Experience the Future of Hair Transplantation The ARTAS Robotic System ARTAS Hair Studio Technology Advanced Harvesting Recipient Site Making Advanced Harvesting ARTAS Hair Studio Recipient Site Making

More information

Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia

Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia ORIGINAL ARTICLES Double-Blind, Placebo-Controlled Pilot Study on the Use of Platelet-Rich Plasma in Women With Female Androgenetic Alopecia Carlos J. Puig, DO,* Robert Reese, DO, and Michelle Peters,

More information

Chapter 2 Relationships between Categorical Variables

Chapter 2 Relationships between Categorical Variables Chapter 2 Relationships between Categorical Variables Introduction: An important field of exploration when analyzing data is the study of relationships between variables. A lot of thought has been put

More information

designed to stimulate collagen

designed to stimulate collagen Discover the volumizer designed to stimulate collagen with results that last over 2 years* Elaine: Age 40 (2.5 vials) Christine: Age 39 (2 vials) Veronica: Age 33 (4 vials) Actual Sculptra Aesthetic patients

More information

SPECIAL TOPIC. Virginia Clinical Research, Inc., Norfolk, VA b. Oregon Dermatology and Research Center, Portland, OR c

SPECIAL TOPIC. Virginia Clinical Research, Inc., Norfolk, VA b. Oregon Dermatology and Research Center, Portland, OR c September 2014 611 Volume 13 Issue 9 Copyright 2014 ORIGINAL ARTICLES Journal of Drugs in Dermatology SPECIAL TOPIC An Aqueous Gel Fixed Combination of Clindamycin Phosphate 1.2% and Benzoyl Peroxide 3.75%

More information

A Double-Blind Randomized Clinical Trial on the Eflectiveness of a Daily Glycolic Acid 5% Formulation in the Treatment of Photoaging

A Double-Blind Randomized Clinical Trial on the Eflectiveness of a Daily Glycolic Acid 5% Formulation in the Treatment of Photoaging A DoubleBlind Randomized Clinical Trial on the Eflectiveness of a Daily Glycolic Acid 5% Formulation in the Treatment of Photoaging PAUL K. THIBAULT, MB, BS JOHN WLODARCZYK, BEc, DIP, MED, STATS PHD ADRIAN

More information

Lisa Chipps, MD, MS, FAAD Assistant Clinical Professor David Geffen School of Medicine at UCLA

Lisa Chipps, MD, MS, FAAD Assistant Clinical Professor David Geffen School of Medicine at UCLA Lisa Chipps, MD, MS, FAAD Assistant Clinical Professor David Geffen School of Medicine at UCLA Presented at The American Academy of Facial Plastic and Reconstructive Surgery Meeting, September, 2011 Provided

More information

Rodan + Fields Dermatologists Skincare Changing skin and changing lives. The Perfect Partnership

Rodan + Fields Dermatologists Skincare Changing skin and changing lives. The Perfect Partnership Rodan + Fields Dermatologists Skincare Changing skin and changing lives The Perfect Partnership Why partnering with Rodan + Fields is the right choice Services currently provides: Hair Services Hair Removal

More information

Color Atlas of Chemical Peels

Color Atlas of Chemical Peels Color Atlas of Chemical Peels Antonella Tosti Maria Pia De Padova Editors Color Atlas of Chemical Peels Second Edition Editors Prof. Dr. Antonella Tosti University of Miami Leonard M. Miller School of

More information

MICRONEEDLING DEVICE (SKIN ROLLER) ENHANCES SKIN S ABSORPTION OF PRODUCTS

MICRONEEDLING DEVICE (SKIN ROLLER) ENHANCES SKIN S ABSORPTION OF PRODUCTS GUNA Clinical Support Doc Dr Jo Serrentino Guna Clinical Support Line 877-486-2383 Clinicalsupport@gunacanada.com GUNA MICRONEEDLING DEVICE APPLICATIONS and TECHNIQUE MICRONEEDLING DEVICE (SKIN ROLLER)

More information

Legato Treatment Results Skin Barrier Breakthrough System

Legato Treatment Results Skin Barrier Breakthrough System Legato Treatment Results Skin Barrier Breakthrough System Maria Claudia Almeida Issa, MD, PhD Associate Professor, Department of Clinical Medicine Fluminense Federal University Rio de Janeiro, Brazil Dr.

More information

Management of acne requires proper application

Management of acne requires proper application DRUG THERAPY TOPICS A Qualitative and Quantitative Assessment of the Application and Use of Topical Acne Medication by Patients James Q. Del Rosso, DO Management of acne requires proper application of

More information

Virtual Mentor American Medical Association Journal of Ethics August 2006, Volume 8, Number 8:

Virtual Mentor American Medical Association Journal of Ethics August 2006, Volume 8, Number 8: Virtual Mentor American Medical Association Journal of Ethics August 2006, Volume 8, Number 8: 503-508. Clinical case Dispensing cosmeceuticals from the office Commentary by Michael H. Gold, MD Mrs. Schweppe

More information

Clinical studies with patients have been carried out on this subject of graft survival and out of body time. They are:

Clinical studies with patients have been carried out on this subject of graft survival and out of body time. They are: Study Initial Date: July 21, 2016 Data Collection Period: Upon CPHS Approval to September 30, 2018 Study Protocol: Comparison of Out of Body Time of Grafts with the Overall Survival Rates using FUE Lead

More information

Dr. Geoffrey Heber and his wife Dr. Debra Davis were recognized as two of the top. magazine.

Dr. Geoffrey Heber and his wife Dr. Debra Davis were recognized as two of the top. magazine. Dr. Geoffrey Heber and his wife Dr. Debra Davis were recognized as two of the top eight cosmetic physicians in 2005 by Vogue magazine. ULTRACEUTICALS is regularly featured ULTRACEUTICALS is regularly featured

More information

EpiCeram Topical therapeutic Skin Barrier Emulsion

EpiCeram Topical therapeutic Skin Barrier Emulsion EpiCeram Topical therapeutic Skin Barrier Emulsion PEDIAPHARM INC. Date of preparation: August 31, 2010 Summary Product Information: EpiCeram Skin Barrier Emulsion is a steroid-free, fragrance - free,

More information

Stakeholder Position of. Andreas Schmidt vice chairman of D.O.T. (German association of professional tattoo artists)

Stakeholder Position of. Andreas Schmidt vice chairman of D.O.T. (German association of professional tattoo artists) Stakeholder Position of Andreas Schmidt vice chairman of D.O.T. (German association of professional tattoo artists) Aims of the organisation D.O.T. Securing the quality standards in the tattoo scene by

More information

Creates younger skin. 1 Profoundly.

Creates younger skin. 1 Profoundly. Creates younger skin. 1 Profoundly. * * *Based on results of a clinical study in 20 patients, measuring improvement in Fitzpatrick Wrinkle Scale at 3 months compared to baseline based on independent review

More information

Comparison of Women s Sizes from SizeUSA and ASTM D Sizing Standard with Focus on the Potential for Mass Customization

Comparison of Women s Sizes from SizeUSA and ASTM D Sizing Standard with Focus on the Potential for Mass Customization Comparison of Women s Sizes from SizeUSA and ASTM D5585-11 Sizing Standard with Focus on the Potential for Mass Customization Siming Guo Ph.D. Program in Textile Technology Management College of Textiles

More information

Tattoo Removal With an Electro-optic Q-Switched Nd:YAG Laser With Unique Pulse Dispersion COS DERM

Tattoo Removal With an Electro-optic Q-Switched Nd:YAG Laser With Unique Pulse Dispersion COS DERM Study Tattoo Removal With an Electro-optic Q-Switched Nd:YAG Laser With Unique Pulse Dispersion Michael Gold, MD The objective of this study was to evaluate the clinical effectiveness of an electro-optic

More information

NEWS RELEASE. CONTACTS: Investors: Lisa DeFrancesco (862) Media: Mark Marmur (862) Ember Garrett (714)

NEWS RELEASE. CONTACTS: Investors: Lisa DeFrancesco (862) Media: Mark Marmur (862) Ember Garrett (714) NEWS RELEASE CONTACTS: Investors: Lisa DeFrancesco (862) 261-7152 Media: Mark Marmur (862) 261-7558 Ember Garrett (714) 246-3525 JUVÉDERM VOLBELLA XC APPROVED BY U.S. FDA FOR USE IN LIPS AND PERIORAL RHYTIDS

More information

AFFINITY - A novel system for direct Intrafollicular infusion of liquid solutions containing active ingredients.

AFFINITY - A novel system for direct Intrafollicular infusion of liquid solutions containing active ingredients. AFFINITY - A novel system for direct Intrafollicular infusion of liquid solutions containing active ingredients. Marina Landau, 1 M.D., Michael Tavger, PhD 1. Dermatology, Wolfson Medical Center, Holon,

More information

Why treat pigmentation disorder in Asians? Softer and clearer skin is a key to looking younger and improved self satisfaction

Why treat pigmentation disorder in Asians? Softer and clearer skin is a key to looking younger and improved self satisfaction Peter Kim FACCS Why treat pigmentation disorder in Asians? Prevalent especially in Asians High demand Fore-ever try to disguise it with thick make ups, c osmeceuticals and other remedies. Self esteem Softer

More information

Companies View on Cosmeceuticals in Indian Context.

Companies View on Cosmeceuticals in Indian Context. Available online at www.jcpronline.in Journal of Current Pharma Research 5 (2), 2015, 1443-1448. Original Article Companies View on Cosmeceuticals in Indian Context. Virendra S.L., Pradeep M., Sreedhar

More information

3M Cavilon No Sting Barrier Film. Realize the potential of proven protection.

3M Cavilon No Sting Barrier Film. Realize the potential of proven protection. 3M Cavilon No Sting Barrier Film Realize the potential of proven protection. The significance of healthcareacquired skin damage. Healthcare-acquired skin damage represents negative clinical outcomes resulting

More information

Clinical Studies Confirm Superior Tattoo Clearance with PicoSure

Clinical Studies Confirm Superior Tattoo Clearance with PicoSure Clinical Studies Confirm Superior Tattoo Clearance with PicoSure By Jeffrey Frentzen, Executive Editor Tattoo removal has graduated from the days of non-selective ablation using carbon dioxide and continuous

More information

SKIN BRIGHTENING SYSTEM THE POWER OF FOAM AND PHOTODAMAGE O F T H E FA C E. Powerful 3-Piece Regimen Kit

SKIN BRIGHTENING SYSTEM THE POWER OF FOAM AND PHOTODAMAGE O F T H E FA C E. Powerful 3-Piece Regimen Kit SKIN BRIGHTENING SYSTEM THE R E V O L U T I O N A RY POWER OF FOAM C L I N I C A L LY P R O V E N T O T R E AT P I G M E N TAT I O N AND PHOTODAMAGE O F T H E FA C E Powerful 3-Piece Regimen Kit Foam drug

More information

Non-Surgical Epicanthoplasty and Rhinoplasty: Epicanthorhinoplasty

Non-Surgical Epicanthoplasty and Rhinoplasty: Epicanthorhinoplasty JKAU: Med. Sci., Vol. 17 No. 2, pp: 3-9 (2010 A.D. / 1431 A.H.) DOI: 10.4197/Med. 17-2.1 Non-Surgical Epicanthoplasty and Rhinoplasty: Epicanthorhinoplasty Amal A. Bukhari, MD, FRCS Department of Ophthalmology,

More information

Male Pattern Balding. About 30 % of men by age 30 and 50 % by age 50 years of age will have androgenetic alopecia or male pattern balding.

Male Pattern Balding. About 30 % of men by age 30 and 50 % by age 50 years of age will have androgenetic alopecia or male pattern balding. 750 West Broadway Suite 905 - Vancouver BC V5Z 1H8 Phone: 604.283.9299 Fax: 604.648.9003 Email: vancouveroffice@donovanmedical.com Web: www.donovanmedical.com Male Pattern Balding How common is Male Pattern

More information

The CARI Guidelines Caring for Australians with Renal Impairment. 12. Prophylaxis for exit site/tunnel infections using mupirocin

The CARI Guidelines Caring for Australians with Renal Impairment. 12. Prophylaxis for exit site/tunnel infections using mupirocin 12. Prophylaxis for exit site/tunnel infections using mupirocin Date written: February 2003 Final submission: July 2004 Guidelines (Include recommendations based on level I or II evidence) Prophylactic

More information

KoC03of. 510(k) SUMMARY. Lexington International, LLC LaserComb. Submitter's Contact Information. Name: David Michaels, Managing Director JAN

KoC03of. 510(k) SUMMARY. Lexington International, LLC LaserComb. Submitter's Contact Information. Name: David Michaels, Managing Director JAN KoC03of 510(k) SUMMARY Lexington International, LLC LaserComb Submitter's Contact Information Name: David Michaels, Managing Director JAN 1 8 2667 Address: Lexington International, LLC 2650 North Military

More information

Natural appearance and increased

Natural appearance and increased Orientation of Multi-Hair Follicles in Nonbald Men: Perpendicular Versus Parallel KUNIYOSHI YAGYU, MD, KOKI HAYASHI, MD, AND STEVEN C. CHANG, MD y BACKGROUND There has been much debate about the orientation

More information

1. M.B.B.S (Hons) University of NSW, Sydney, Australia. 3. Diploma Dermatology University of Cardiff, United Kingdom

1. M.B.B.S (Hons) University of NSW, Sydney, Australia. 3. Diploma Dermatology University of Cardiff, United Kingdom Dr Ian Haris (Australia) EDUCATION AND QUALIFICATIONS 1. M.B.B.S (Hons) University of NSW, Sydney, Australia 3. Diploma Dermatology University of Cardiff, United Kingdom 4. Certificate IV TESOL Sydney

More information

TEOSYAL PEN: Personal experience after 12 months on 285 consecutive patients

TEOSYAL PEN: Personal experience after 12 months on 285 consecutive patients TEOSYAL PEN: Personal experience after 12 months on 285 consecutive patients Dr. Dell Avanzato Roberto AMWC 2016, 14 th Aesthetic & Anti-aging Medicine World Congress 31 March, 1 2 April, 2016 BACKGROUND

More information

New Filler Approvals Refyne, Defyne, Vollure, Revanesse. Karol A Gutowski, MD, FACS Hot Topics

New Filler Approvals Refyne, Defyne, Vollure, Revanesse. Karol A Gutowski, MD, FACS Hot Topics New Filler Approvals Refyne, Defyne, Vollure, Revanesse Karol A Gutowski, MD, FACS Hot Topics Disclosures Merz - Advisory Board Suneva Medical - Instructor Will use brand names due to lack of distinguishing

More information

FACIAL ARTS. Manufacturer: naturelize GmbH Kasseler Straße Bad Emstal Germany Phone: +49 (0)

FACIAL ARTS. Manufacturer: naturelize GmbH Kasseler Straße Bad Emstal Germany Phone: +49 (0) Manufacturer: naturelize GmbH Kasseler Straße 47 34308 Bad Emstal Germany Phone: +49 (0) 5624 926 7630 www.naturelize.com Fax: +49 (0) 5624 926 7639 Mail: customer support@naturelize.com supporting esthetic

More information

Attractiveness Fades Quicker Than Color: Lay Person Ratings of Age and Beauty on Female Facial Photographs in Comparison to Color Measurements

Attractiveness Fades Quicker Than Color: Lay Person Ratings of Age and Beauty on Female Facial Photographs in Comparison to Color Measurements 1 Attractiveness Fades Quicker Than Color: Lay Person Ratings of Age and Beauty on Female Facial Photographs in Comparison to Color Measurements Stephan Bielfeldt, Marianne Brandt, Klaus-Peter Wilhelm

More information

Hyalurosmooth. by Beauty Creations. Natural fine line and wrinkle filler

Hyalurosmooth. by Beauty Creations. Natural fine line and wrinkle filler Hyalurosmooth by Beauty Creations Natural fine line and wrinkle filler Hyalurosmooth Botanical alternative to hyaluronic acid Smoothing and filling of fine lines and wrinkles by injecting «fillers» such

More information

Nasal Decolonization: What Agent is Most Effective to Prevent Surgical Site Infections

Nasal Decolonization: What Agent is Most Effective to Prevent Surgical Site Infections Nasal Decolonization: What Agent is Most Effective to Prevent Surgical Site Infections Ed Septimus, MD, FIDSA, FACP, FSHEA Therapeutics Research and Infectious Disease Epidemiology, Department of Population

More information

As Engrossed: S2/1/01. By: Representatives Bledsoe, Borhauer, Bond, Rodgers, Green. For An Act To Be Entitled

As Engrossed: S2/1/01. By: Representatives Bledsoe, Borhauer, Bond, Rodgers, Green. For An Act To Be Entitled Stricken language would be deleted from and underlined language would be added to the law as it existed prior to this session of the General Assembly. 0 State of Arkansas As Engrossed: S//0 rd General

More information

PRE-CONGRESS. Tuesday, November 7 th, 2017 HOSPITAL Registration PRE-CONGRESS WORKSHOP LIPOSUCTION AND LIPOTRANSFER LIVE 09.

PRE-CONGRESS. Tuesday, November 7 th, 2017 HOSPITAL Registration PRE-CONGRESS WORKSHOP LIPOSUCTION AND LIPOTRANSFER LIVE 09. PRE-CONGRESS Tuesday, November 7 th, 2017 HOSPITAL Registration 08.30 10.30 Coffee Break 11 Wednesday, November 8 th, 2017 ANATOMY DEVICES DERM SURGERY REGISTRATION 08.30 OPENING CEREMONY Hair transplantation:

More information

The secondary objective was to evaluate the cosmetic properties and its efficacy after 28 days.

The secondary objective was to evaluate the cosmetic properties and its efficacy after 28 days. P0090 CLINICAL EVALUATION OF CUTANEOUS SAFETY AND EFFICACY OF A FACE EMULSION CONTAINING MYRTACIN EXTRACT, PP VITAMIN ANS SABAL EXTRACT ON ACNE PRONE SKIN SUBJECTS TREATED BY TOPICAL ANTI ACNE DRUG THERAPY.

More information

PLEASE SCROLL DOWN FOR ARTICLE

PLEASE SCROLL DOWN FOR ARTICLE This article was downloaded by: [Mulholland, R. Stephen] On: 25 May 2009 Access details: Access Details: [subscription number 911659728] Publisher Informa Healthcare Informa Ltd Registered in England and

More information

AMERICAN ACADEMY OF AESTHETIC MEDICINE

AMERICAN ACADEMY OF AESTHETIC MEDICINE AMERICAN ACADEMY OF AESTHETIC MEDICINE Level 2 - Diploma Course in Aesthetic Medicine (5-Day Course) 4-8 December 2015 Dubai, UAE DAY 1 (December 4, 2015): Dr. David Melamed (USA) PRP AND MICRODERMABRASION

More information

The Cleavage Imprinting Technique for Ensuring Mirror Image Medial Scar Symmetry in Reduction Mammoplasty

The Cleavage Imprinting Technique for Ensuring Mirror Image Medial Scar Symmetry in Reduction Mammoplasty IBIMA Publishing Plastic Surgery: An International Journal http://www.ibimapublishing.com/journals/psij/psi.html Vol. 2013 (2013), Article ID 603862, 6 pages DOI: 10.5171/2013.603862 Research Article The

More information

Regulation of Sunscreens in Australia

Regulation of Sunscreens in Australia Regulation of Sunscreens in Australia Dr Cheryl McRae Assistant Secretary Complementary and OTC Medicines Branch The Sunscreen Summit, Brisbane, 19 March 2018 Regulation of Sunscreens in Australia In Australia,

More information

TrichoScan Smart Version 1.0

TrichoScan Smart Version 1.0 USER MANUAL TrichoScan Smart Version 1.0 TRICHOLOG GmbH D-79117 Freiburg, Germany DatInf GmbH D-72074 Tübingen, Germany Manual TrichoScan Smart 09/2008 Index Introduction 3 Background 3 TrichoScan Smart

More information

The comparison between intradermal injection of abobotulinumtoxina and normal saline for face-lifting: a split-face randomized controlled trial

The comparison between intradermal injection of abobotulinumtoxina and normal saline for face-lifting: a split-face randomized controlled trial Original Contribution Journal of Cosmetic Dermatology, 15, 452--457 The comparison between intradermal injection of abobotulinumtoxina and normal saline for face-lifting: a split-face randomized controlled

More information

Below is the indication and summary of the most serious and most common risks associated with the use of Natroba. 1

Below is the indication and summary of the most serious and most common risks associated with the use of Natroba. 1 DEPARTMENT OF HEALTH & HUMAN SERVICES Public Health Service Food and Drug Administration Silver Spring, MD 20993 TRANSMITTED BY FACSIMILE Kerry W. Mettert Director, Quality and Regulatory 11550 North Meridian

More information

Five-Year Safety and Efficacy of a Novel Polymethylmethacrylate Aesthetic Soft Tissue Filler for the Correction of...

Five-Year Safety and Efficacy of a Novel Polymethylmethacrylate Aesthetic Soft Tissue Filler for the Correction of... See discussions, stats, and author profiles for this publication at: https://www.researchgate.net/publication/5762787 Five-Year Safety and Efficacy of a Novel Polymethylmethacrylate Aesthetic Soft Tissue

More information

Adhesive tape: A valuable material following preoperative site hair shaving!!

Adhesive tape: A valuable material following preoperative site hair shaving!! Article ID: WMC004173 ISSN 2046-1690 Adhesive tape: A valuable material following preoperative site hair shaving!! Corresponding Author: Mr. Andrej Salibi, STR Burns & Plastics, Department of Plastic Surgery,

More information

Diagnosis and Therapy of Tattoo Complications

Diagnosis and Therapy of Tattoo Complications Diagnosis and Therapy of Tattoo Complications Current Problems in Dermatology Vol. 52 Series Editors Peter Itin Basel Gregor B.E. Jemec Roskilde Diagnosis and Therapy of Tattoo Complications With Atlas

More information

with Hydrolock Technology

with Hydrolock Technology Exufiber brand dressings: Hydrolock Technology dressings you would design Gelling fibre dressings reinvented Reduce the risk of infection with Exufiber Ag+ 1-4 Introducing dressing you would design Under

More information

Chapter III Part- I: Consumers perception toward cosmeceuticals Introduction Characteristics of Indian consumer behavior

Chapter III Part- I: Consumers perception toward cosmeceuticals Introduction Characteristics of Indian consumer behavior Understanding perception of consumers and dermatologists is essential part of pharmaceutical and cosmetic business strategy. Whereas to understand perception of pharmaceutical and cosmetic companies view

More information

AMERICAN ACADEMY OF AESTHETIC MEDICINE

AMERICAN ACADEMY OF AESTHETIC MEDICINE AMERICAN ACADEMY OF AESTHETIC MEDICINE Level 2 - Diploma Course in Aesthetic Medicine (5-Day Course) August 4-8, 2016 Dubai, UAE DAY 1: August 4, 2016: Dr. Riekie Smit MESOTHERAPY 8:00 8: 30 Registration

More information

SPONSORED BY Jan Marini Skin Research A SUPERIOR SOLUTION FOR HYPERPIGMENTATION: SPLIT-FACE STUDY RESULTS WITH MARINI LUMINATE FACE LOTION

SPONSORED BY Jan Marini Skin Research A SUPERIOR SOLUTION FOR HYPERPIGMENTATION: SPLIT-FACE STUDY RESULTS WITH MARINI LUMINATE FACE LOTION A SUPERIOR SOLUTION FOR HYPERPIGMENTATION: SPLIT-FACE STUDY RESULTS WITH MARINI LUMINATE FACE LOTION COMPREHENSIVE SOLUTIONS FOR AGING HANDS: PRODUCT & IN-OFFICE TREATMENT COMBINATIONS PEELING BACK THE

More information

INJECTING SCIENCE INTO YOUR BEAUTY

INJECTING SCIENCE INTO YOUR BEAUTY INJECTING SCIENCE INTO YOUR BEAUTY REJUVENATE YOUR NATURAL BEAUTY WITH INSTANT, LASTING RESULTS PLURYAL MD SKIN SOLUTIONS LABORATORIES, THE CREATORS BEHIND BEAUTY SCIENCE UNDERSTANDING SKIN AGING > Due

More information

Looking forward to welcoming you to Malmö, Hans-Joachim Laubach ESLD President

Looking forward to welcoming you to Malmö, Hans-Joachim Laubach ESLD President ESLD is honoured to introduce you to its highly specialized Hands-on Laser and EBD Teaching Course, in collaboration with the Skåne University, Sweden. The course will provide participants with up-to-date

More information

Roughly 25 years since Albert Kligman, MD introduced

Roughly 25 years since Albert Kligman, MD introduced Inside Cosmeceutical Marketing Claims Dermatologists and their patients may wonder what makes a product dermatologist tested or clinically proven. Here s what you need to know. By Leslie Baumann, MD Roughly

More information

Levan. A Natural Anti-Aging Humectant

Levan. A Natural Anti-Aging Humectant Levan A Natural Anti-Aging Humectant What is Levan? Levan is a naturally occurring bio-polymer a polyfructose. Levan molecules are formed from sucrose by an enzymatic process. Typically structured as β-2,6

More information

International Efficacy Survey

International Efficacy Survey International Efficacy Survey on Wrinkle Treatment Products for Narhex Australia Pty Ltd By Dr Vyt Garnys Ph.D., A.R.A.C.I., A.I.M.M., Managing Director Cetec Pty Ltd Consulting - Enterprises in Technology

More information

AESTHETIC PRECISION THE SAFEST AND MOST PRECISE LASER TREATMENT SOLUTION AVAILABLE FOR PIGMENTED LESIONS AND MULTI-COLOR TATTOO REMOVAL

AESTHETIC PRECISION THE SAFEST AND MOST PRECISE LASER TREATMENT SOLUTION AVAILABLE FOR PIGMENTED LESIONS AND MULTI-COLOR TATTOO REMOVAL Q-SWITCHED RUBY LASER SYSTEM AESTHETIC PRECISION THE SAFEST AND MOST PRECISE LASER TREATMENT SOLUTION AVAILABLE FOR PIGMENTED LESIONS AND MULTI-COLOR TATTOO REMOVAL INTRODUCTION The SINON II Q-switched

More information

Medical Aesthetic Devices: Technologies and Global Markets

Medical Aesthetic Devices: Technologies and Global Markets Report Information More information from: https://www.wiseguyreports.com/reports/3168766-medical-aesthetic-devices-technologies-and-globalmarkets Medical Aesthetic Devices: Technologies and Global Markets

More information

THE SCIENCE WHITE PAPER SERIES OF IMAGE SKINCARE: by Marc A. Ronert MD PhD, Clinical Director Image Skincare

THE SCIENCE WHITE PAPER SERIES OF IMAGE SKINCARE: by Marc A. Ronert MD PhD, Clinical Director Image Skincare THE SCIENCE WHITE PAPER SERIES OF IMAGE SKINCARE: Clear Cell Line containing Benzoyl Peroxide by Marc A. Ronert MD PhD, Clinical Director Image Skincare ABSTRACT Image Skincare offers products with many

More information

Literature Scan: Topical Antiparasitics

Literature Scan: Topical Antiparasitics Copyright 2012 Oregon State University. All Rights Reserved Drug Use Research & Management Program Oregon State University, 500 Summer Street NE, E35 Salem, Oregon 97301-1079 Phone 503-947-5220 Fax 503-947-1119

More information

Comparison between axillary hair removal with a continuously scanned Diode laser and a spot-to-spot scanned Alexandrite Laser (EpiCon-Study)

Comparison between axillary hair removal with a continuously scanned Diode laser and a spot-to-spot scanned Alexandrite Laser (EpiCon-Study) Clinical Study - Abstract Clinical Study - Abstract Comparison between axillary hair removal with a continuously scanned Diode laser and a spot-to-spot scanned Alexandrite Laser (EpiCon-Study) Bodendorf

More information

Results Clinical Photography

Results Clinical Photography A High-Strength Retinol Serum Enhanced with N-Acetyl Glucosamine Provides Significant Anti-Aging Effects in Combination with a Comprehensive Skincare Regimen Joel Schlessinger, MD ; Brenda L. Edison, BA

More information

Scientifically and Clinically Proven Anti-Aging Skin Serums

Scientifically and Clinically Proven Anti-Aging Skin Serums Scientifically and Clinically Proven Anti-Aging Skin Serums This white paper provides detailed information on the efficacy and scientific evidence of topically applied skin care serums, with an emphasis

More information

AMERICAN ACADEMY OF AESTHETIC MEDICINE Level 2 - Diploma Course in Aesthetic Medicine (5-Day Course)

AMERICAN ACADEMY OF AESTHETIC MEDICINE Level 2 - Diploma Course in Aesthetic Medicine (5-Day Course) AMERICAN ACADEMY OF AESTHETIC MEDICINE Level 2 - Diploma Course in Aesthetic Medicine (5-Day Course) FACULTIES: 10-14 September 2015 Mumbai- India DAY 1 (September 10, 2015): Dr. Thomas Berger COSMETIC

More information

a revolution in Q-Switched technology

a revolution in Q-Switched technology a revolution in Q-Switched technology Proven Reliability and Versatility Revlite s proven reliability and versatility enable fast treatments on all skin types for predictable and reproducible results.

More information

H 7915 S T A T E O F R H O D E I S L A N D

H 7915 S T A T E O F R H O D E I S L A N D LC00 0 -- H S T A T E O F R H O D E I S L A N D IN GENERAL ASSEMBLY JANUARY SESSION, A.D. 0 A N A C T RELATING TO FOOD AND DRUGS - RHODE ISLAND FOOD, DRUGS, AND COSMETICS ACT Introduced By: Representatives

More information

Lux2940 Laser Advances Resurfacing. September/October 2007 Circulation 18,000

Lux2940 Laser Advances Resurfacing. September/October 2007 Circulation 18,000 September/October 2007 Circulation 18,000 www.miinews.com Lux2940 Laser Advances Resurfacing A new single treatment micro-fractional Er:YAG laser device has restored ablative treatments, this time with

More information

Safety and Efficacy of a Novel Diffractive Lens Array Using a Picosecond 755 nm Alexandrite Laser for Treatment of Wrinkles

Safety and Efficacy of a Novel Diffractive Lens Array Using a Picosecond 755 nm Alexandrite Laser for Treatment of Wrinkles Lasers in Surgery and Medicine 49:40 44 (2017) Safety and Efficacy of a Novel Diffractive Lens Array Using a Picosecond 755 nm Alexandrite Laser for Treatment of Wrinkles Robert A. Weiss, MD, FAAD, 1 David

More information

Summary. Original Contribution. 1. Tess Mauricio MD 1, 2. Yoram Karmon PhD 2, 3. Alain Khaiat PhD 2,3,4 Article first published online: 8 DEC 2011

Summary. Original Contribution. 1. Tess Mauricio MD 1, 2. Yoram Karmon PhD 2, 3. Alain Khaiat PhD 2,3,4 Article first published online: 8 DEC 2011 Original Contribution A randomized and placebo-controlled study to compare the skin-lightening efficacy and safety of lignin peroxidase cream vs. 2% hydroquinone cream 1. Tess Mauricio MD 1, 2. Yoram Karmon

More information

Facial Resurfacing By David J. Goldberg

Facial Resurfacing By David J. Goldberg Facial Resurfacing By David J. Goldberg Resurfacing and Contouring Course - American - Resurfacing and Contouring Course. Date Paul M. Friedman, M.D., David J. Goldberg, M.D that have an interest in skin

More information

Luminant Review - The Best Solution For Removing. Do You Want A Glowing Beautiful Skin? Available In United States Only

Luminant Review - The Best Solution For Removing. Do You Want A Glowing Beautiful Skin? Available In United States Only Downloaded from: justpaste.it/dnsx Luminant Review - The Best Solution For Removing Unwanted Skin Problems Do You Want A Glowing Beautiful Skin? Luminant Review revealed the main advantages of Luminant

More information

Anti Wrinkle Injections INFORMATION GUIDE

Anti Wrinkle Injections INFORMATION GUIDE Anti Wrinkle Injections INFORMATION GUIDE Dr Shobhna Singh 2 Anti Wrinkle Injections Dr Shobhna Singh has decades of experience treating a wide range of skin conditions, with a special interest in the

More information

Dr David B Eccleston M.B., Ch.B.

Dr David B Eccleston M.B., Ch.B. Dr David B Eccleston M.B., Ch.B. Medico-Legal Secretary, SM Legal Services, High Pines, 71 Walsall Road, Little Aston, Sutton Coldfield, Birmingham, B74 3BA Tel: 0121 352 0517 Fax: 0121 353 9408 mls@smlegalservices.co.uk

More information

Jeffrey Rapaport, MD, PA

Jeffrey Rapaport, MD, PA PRP: WHERE ARE WE? Jeffrey Rapaport, MD, PA Fellow, American Academy of Dermatology Fellow, American Society for Dermatologic Surgery AAD Presenta9on Hand Outs 2.17.2018 Large Volume/Double Spin/Complex

More information

BAXTER ANNOUNCES U.S. FDA APPROVAL AND COMMERCIAL LAUNCH OF READY-TO-USE CLINDAMYCIN INJECTION IN SALINE

BAXTER ANNOUNCES U.S. FDA APPROVAL AND COMMERCIAL LAUNCH OF READY-TO-USE CLINDAMYCIN INJECTION IN SALINE FOR IMMEDIATE RELEASE Media Contact Eric Tatro, (224) 948-5353 media@baxter.com Investor Contact Clare Trachtman, (224) 948-3085 BAXTER ANNOUNCES U.S. FDA APPROVAL AND COMMERCIAL LAUNCH OF READY-TO-USE

More information

Value-Based Healthcare Health Economics Value-Based Procurement

Value-Based Healthcare Health Economics Value-Based Procurement Value-Based Healthcare Health Economics Value-Based Procurement Martin Bergius Project Manager Nordic Medtech Growth 2 martin.bergius@bsci.com +46 72 501 46 88 Health Economics NMG2 Value-Based Healthcare

More information

GSK Clinical Study Register

GSK Clinical Study Register In February 2013, GlaxoSmithKline (GSK) announced a commitment to further clinical transparency through the public disclosure of GSK Clinical Study Reports (CSRs) on the GSK Clinical Study Register. The

More information

Products to Repair and Augment the Skin. Robert Daniels, CEO

Products to Repair and Augment the Skin. Robert Daniels, CEO Products to Repair and Augment the Skin Robert Daniels, CEO r.daniels@elastagen.com Elastin gives skin its suppleness and elasticity 2 Elastin breakdown leads to aged and damaged skin Teenage boy: cutis

More information