CAMPO RESEARCH PTE LTD Level 30, 6 Battery Road, Singapore Tel: (65) / 202 / Direct Fax (65) /

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1 CAMPO RESEARCH PTE LTD Level 30, 6 Battery Road, Singapore Tel: (65) / 202 / Direct Fax (65) / sales@campo-research.com Website: http/// CAMPO Multi-Purpose Cosmetic Base Chemicals & Active Ingredients CAMPO Novel Functional Active Cosmetic Ingredient & Raw Materials

2 INDEX Campo is the World Leader Description Characteristics Composition Application About TRANSPHERES IMPORTANT NOTICE Specifications may change without prior notice. Information contained in this technical literature is believed to be accurate and is offered in good faith for the benefit of the customer. The company, however, cannot assume any liability or risk involved in the use of its natural products or their derivatives, since the conditions of use are beyond our control. Statements concerning the possible use are not intended as recommendations to use our products in the infringement of any patent. We make no warranty of any kind; expressed or implied, other than that the material conforms to the applicable standard specifications. Ask about our Herbal Natural Products Chemistry Consultancy Services Product Registration EEC/UK New Drug Development (NDA-US); Quasi-Drug Topicals (MOHW_Japan); Development of Standards, Analysis & Profiles of Phytochemicals; Literature searches, Cultivation of Medicinal Plants, Clinical-Trials, Development of new uses for Phytochemicals and Extracts; Contract Research and Development Work in Natural Products for Novel Drugs, New Cosmetic Active Ingredients for Active Topica/OTC Cosmetic with functionality and Consumer-perceivable immediate-results, New Food Ingredients for Nutraceuticals & Functional Foods. 2

3 Campo is the World Leader Today in the ingredient development, production and marketing of Novel Cosmetic Ingredients from Natural Product Novel Drug Discovery, on the International Cosmetic & Beauty markets. Campo Cosmetic Active Ingredients are derivatives of the Novel Drug Discovery from Natural Products programs. Since as a member of a large Tobbacco Group in Japan (since 1863), with a diversity of investment portofolio from Chemicals to Bio-tech Farms, from Medical equipments to Scientific analyticals; Campo has access and various applications done in-house State of Art scientific R&D facilities for new novel natural ingredients and super-smart-trophic active targeting skin delivery systems like "Transpheres Bio-Molecular Encapsulation Technology", "UV-enzymes, UV-extremozymes, Phyto-p53s, Leuco-melanin (colorless melanin) catalysts & precursorsenzymes, Campo Natural Skin-whitening Agents, Anti-aging phyto-hormones, detergency Fruit enzymes for skin & hair care, Anti-oxidant & Anti-aging Fruit enzymes and the engimatic Neem" among other novel ingredients for new generation of Novel skin & hair care cosmetic products. Now the International cosmetic industry have been greatly impressed for the past ten years with Campo's Active Ingredients of novel drug discovery but the industry is yet to see the best of Campo's Novelties range of 'super-smart targeting' delivery application-specific ingredients and their intelligent topical payload delivery systems. Campo's continual focus will be the Natural sourced Active ingredients combined with super-smart trophic topical delivery systems with target specific adaptogenic payload delivery; to reversal or remediate or ameliorate certain skin & hair afflication or conditions and while remaining inert to- or enhancing of-normal skin & hair cells. With these new bio-skin topical remedies delivery systems, even the humble Aloe vera can be in for a new lease of life to function as new cosmoceutical ingredient as the Aloe can function more accurately in delivery of its skin-correcting functional activities to the required undernourished problematic skin-zones. Due to the present lack of knowledge of Aloe in the industry,especially of Aloe suppliers, it is still an under-utilised natural active which has more wonders than the beauty industry is aware of, due to misconceptions in formulation techniques of Aloe in any given topical formulation. 3

4 Tomorrow Campo has already an array of "super-smart-target topical delivery systems and new and existing intelligent cosmetic active ingredients that will combine and symbiotically functions as an 'single entity' (intelligent active ingredients and super-smart-target payload delivery systems) arsenals" in treating the most serious aging or poorly maintained skin & hair conditions, and enhance the natural beauty of all racial and age group of women in the present and next millenium. Campo will be more than pleased to work and develop for any size small or large cosmetic houses, salons, day-spas, and beauty palours to introduce their unique Brand-name topicals, OTC, Cosmetics, Skin-care and Hair-care products, which imparts the state of art know-how of novel drug discovery and immediate consumerprecievable results. TRANSPHERES, Innovative form of Cosmetics, OTC/Topicals Description Transpheres are colored or colorless microspheres encoupled with live skin-enzymes and are created as nature mimic bio-molecules by the high-tech bio-science of Campo Research, of Kyoto,Japan. These bio-molecules (Transpheres) are classified by color range and the inner phase's form in accordance with customer's requirements such as for General Cosmetics: Transpheres Liquid Crytals, Transpheres Makeup Base, Transphere Skin-Essence, and Transpheres Foundation, and Active Delivery Systems, etc. New types of Cosmetic Products with high-end applications and with characteristic novel functionalities can be achieved with these unique enzymatic microspheres- TRANSPHERES Other than in above spherical shapes, other shapes like flakes, evening-stars, christmas-stars are also available on request. Characteristics Most biochemically active molecules and Enzymes are fragile when they are removed from their natural protective environment, they are much more vulnerable to chemical and physical change. Storage and delivery of these actives are therefore fundamental technical challenges with commercial repercussions. TRANSPHERES a drug delivery system with intact 4

5 bioactive, bioavailablity and biostability is the biotechnology solution and a cosmetic formulator's and marketer s dream came true of; to these challenges. Applications include decorative cosmetics, skin & hair care, fragrances, perfumes and cosmoceuticals. (see also Private-Label Cosmeceuticals) Among the many novel applications of TRANSPHERES are immunological agents designed to look like a virus without the virus's harmful genetic material; and other OTC/Topical & Pharmaceutical Drug Delivery Systems (structures available on request) Composition Experiments of nature have disclosed the principles underlying the TRANSPHERES family of coupling-enzymatic-biomolecules. When in dry and in the solid state, these enzymatic biomolecules exhibit water-like properties that preserves the conformation and activity of these biomolecules. Application Any type of Makeup products can be incorporated into Microsphere based products and similarly any kind of skincare and hair-care products can be formulated with Microspheres into new novel aesthetic image Cosmetic products; as Transpheres delivery systems are exact-copy-designed of Nature to improve efficacy and deliver with super smartness the target of the incorporated active ingredients for novel new cosmetic concepts. Transpheres has skin & air 5

6 substantive unique amphillic payloads like hydrophillic and lipo-phillic (duality natured) activities. TRANSPHERES Liquid Crystal : 5~20% in Skin care products. TRANSPHERES Make-up base Skin-Essence Foundation, etc : 30 ~50% in cosmetic formulation The Unique TRANSPHERES with the Beauty Pharmaceutical Ingredients for high-tech Skin Care Products. Description of Transpheres Facial Line For perfect skin tone, make-up and high sun protection factors (SPF Value /UV Absorption rate) TRANSPHERES in Transpheres Sun Makeup base has more than three times in quantity of the active beauty pharmaceutical ingredients Transpheres Sun Makeup base has the prominent control effect of skin tone, high skin compatibility & protection effect from UV. This encapsulated Makeup base is free of oil makes skin clear as a crystal without greasy stickness or tackness and control skin tone freely with various colors of green, blue, coral, etc. For Skin Whitening without the loss of CoEnzymes Q10 TRANSPHERES Core Whitening Essence has the novel whitening effect without skin irritation and without loss of the CoEnzyme Q10 and over the moisturizing & nourishing effect with the novel beauty pharmaceutical ingredients. This encapsulated Whitening Essence has excellent skin compatibility & penetration, also anti-oxidation effect. 6

7 About TRANSPHERES, innovative form of cosmetics Transpheres are colored microspheres created by high bio-technology of Campo It is classified by color and inner phase's form in accordance with customer's requirements like Liquid Crytals, makeup base, essence, foundation, etc. You can produce characteristic cosmetic products with supreme active functions and consumer-preceivable results when novel active ingredients are applied from these unique microspheres, TRANSPHERES with it super smart delivery on specific targets. Most biochemically active molecules are fragile. When removed from their natural environment, they are much more vulnerable to chemical and physical change. Storage and delivery are therefore fundamental commercial challenges. TRANSPHERES technology is a solution to these challenges. Applications include cosmetics, skin and hair care, fragrances, perfumes and cosmoceuticals. Among the many applications of TRANSPHERES are immunological agents, natural food supplementss, natural insect repellents and natural pesticides designed to act as natural activity from specific metabolism or natural biosynthesis transformation pathways without the wild gene renegade activities. 7

8 DISCLAIMER : The information contained herein is accurate to the best knowledge and belief of Campo Research Pte Ltd, and specification quoted may change without prior notice. Information contained in this technical literature is believed to be accurate and is offered in good faith for the benefit of the customer. The company, Campo Research Pte Ltd, however, cannot assume any liabilities or risks involved in the use of its natural products or their derivatives or raw materials or ingredients, since the conditions of use are beyond Campo Research Pte Ltd s control. Statements concerning the possible use are not intended as recommendations to use our materials in the infringement of any patents or infringements of mandatory regulatory requirements or without any safety evaluations conducted when used in combination with materials of other suppliers.. We make no warranty of any kind, expressed or implied, other than that the material conforms to the applicable standard specifications. Campo Research Pte Ltd accepts no liabilities of whatsoever either expressed or as otherwise arising out of the information supplied, the application, adaptation or processing of the products described herein, or the use of other materials in lieu of the Campo materials or the use of Campo raw materials or ingredients in conjunction with any other products and raw materials. The use of Campo Research Pte Ltd's raw materials or ingredients in any formulations are to be compulsory tested and to be assayed for safety and toxicology profiles evaluations and according the mandatory regulations as required by the laws and regulations of the countries where the evaluation and use of Campo Research Pte Ltd's raw materials or ingredients has been formulated as single components in any carrier systems or as in multi-components formularies. The end-users, marketers; manufacturers, formulation laboratories or importers of Campo Research Pte Ltd' raw materials and ingredients which are incorporated into any formularies as formulated or re-sold or re-exported or assayed in accordance with any mandatory regulatory requirements of any country or infringement of any patents assume all liabilities as that may arise out of the use of Campo Research Pte Ltd's raw materials and ingredients in any formularies in combination with raw materials and ingredients of other suppliers or as single components in any carriers. The definition of users as mentioned in these instances are manufacturers, marketers, formulation laboratories, consultants, and importers assumed all liabilities arising as either personal injuries suits, infringements of patents suits, infringements of or failures to meet regulatory requirements suits of a formulary either as single components in any carrier systems or in as multi-components formularies in which are may consist of a Campo Research Pte Ltd's raw material or ingredients IMPORTANT NOTICE Specifications may change without prior notice. Information contained in this technical literature is believed to be accurate and is offered in good faith for the benefit of the customer. The company, however, cannot assume any liability or risk involved in the use of its natural products or their derivatives, since the conditions of use are beyond our control. Statements concerning the possible use are not intended as recommendations to use our products in the infringement of any patent. We make no warranty of any kind; expressed or implied, other than that the material conforms to the applicable standard specifications. 8