SDS (SAFETY DATA SHEET)
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1 SDS (SAFETY DATA SHEET) 1. Identification of the substance/mixture and of the company/undertaking Identification of the substance/preparation Product name 10X Tris-Borate-EDTA (TBE) For Research Use (RUO) Only. Not intended for human or animal diagnostic or therapeutic uses. Company/Undertaking Identification American BioInnovations 53 Loveton Cir Suite 104 Sparks, MD USA GHS - Classification Signal Word DANGER 2. Hazards identification Health Hazard Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Irritation Category 2 Specific Target Organ Systematic Toxicity (single exposure) Category 3 Reproductive Toxicity Category 1B Page 1 / 5
2 Physical Hazards Not hazardous Hazard Statements H315 Causes Skin Irritation H319 Causes Serious Eye Irritation H335 May Cause Respiratory Irritation H360 May damage Fertility or the Unborn Child if inhaled Precautionary Statements P261 Avoid breathing dust/fume/gas/mist/vapors/spray P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical attention/advice Principle Routes of Exposure/ Potential Health effects Eyes Irritating to eyes. Skin Irritating to skin. Inhalation Irritating to respiratory system. Ingestion May be harmful if swallowed. Ingestion may cause gastrointestinal irritation, nausea, vomiting, and diarrhea. Specific effects Carcinogenic effects Mutagenic effects Reproductive toxicity Sensitization Target Organ Effects May impair fertility. May cause harm to the unborn child. No known effects under normal use conditions. HMIS Health 1 * chronic hazard Flammability 0 Reactivity 0 3. Composition/information on ingredients Chemical Name CAS-No EINECS-No Weight% TRIS Base Boric acid We recommend handling all chemicals with caution. 4. First aid measures Skin contact Eye contact Rinse with plenty of water. Remove and wash contaminated clothing before re-use. Immediate medical attention is requires. Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is requires. Page 2 / 5
3 Ingestion Inhalation Notes to physician Call a physician or Poison Control Center immediately. Never give anything by mouth to an unconscious person. If symptoms persist, call a physician. Do not induce vomiting without medical advice. Move to fresh air. If not breathing, give artificial respiration. Call a physician or Poison Control Center immediately. Treat symptomatically. 5. Fire-fighting measures Suitable extinguishing media Special protective equipment for firefighters Water spray. Carbon dioxide (CO 2 ). Foam. Dry chemical. Wear self-contained breathing apparatus and protective suit. 6. Accidental release measures Personal precautions Methods for cleaning up Ensure adequate ventilation. Avoid contact with skin, eyes, and clothing. Use personal protective equipment. Soak up with inert absorbent material. Environmental precautions Prevent further leakage or spillage, if safe to do so. Prevent product from entering drains. See Section 12 for additional information. 7. Handling and storage Handling Storage Always wear recommended Personal Protective Equipment. No special handling advice required. Keep in a dry, cool and well-ventilated place. Store in properly labeled containers. Page 3 / 5
4 8. Exposure controls/personal protection Exposure limits Chemical Name OSHA PEL OSHA PEL (Ceiling) ACGIH OEL (TWA) Boric acid mg/m 3 6 mg/m 3 ACGIH OEL (STEL) Engineering measures Ensure adequate ventilation, especially in confined areas. Personal protective equipment Respiratory protection Hand protection Eye protection Skin and body protection. Hygiene measures In case of insufficient ventilation, wear suitable respiratory equipment. Impervious gloves. Safety glasses with side-shields. Lightweight protective clothing. Handle in accordance with good industrial hygiene and safety practice. Environmental exposure controls to contaminate ground water system. Prevent product from entering drains. Do not allow material 9. Physical and chemical properties General Information Form Appearance Odor Boiling Point/Range Melting point/range Flash point Autoignition temperature Oxidizing properties Water solubility Liquid Colorless No information available No information available soluble 10. Stability and reactivity Stability Materials to avoid Hazardous decomposition products Polymerization Stable under normal conditions. No information available under normal processing. Page 4 / 5
5 11. Toxicological information Acute toxicity Chemical Name LD50 (oral, rat/mouse) LD50 (dermal, rat/mouse) LC50 (inhalation, rat/mouse) TRIS Base 5900 mg/kg Rat) No Data Available No Data Available Boric acid 2600 mg/kg (Rat) No Data Available >0.16 mg/l (Rat) Principle Routes of Exposure/ Potential Health effects Eyes Irritating to eyes. Skin Irritating to skin. Inhalation Irritating to respiratory system. Ingestion May be harmful if swallowed. Ingestion may cause gastrointestinal irritation, nausea, vomiting, and diarrhea. Carcinogenic effects Mutagenic effects Reproductive toxicity May impair fertility. May cause harm to the unborn child. Sensitization Target Organ Effects under normal use conditions. 12. Ecological information Ecotoxicity effects Mobility Biodegradation Bioaccumulation Dispose of in accordance with local regulations. 13. Disposal considerations 14. Transport information IATA Proper shipping name Hazard Class Subsidiary Class Packing Group UN-No Not classified as dangerous in the meaning of transport regulations 15. Regulatory information Component TRIS Base (10-30) Boric acid (3-7) TSCA Listed Listed Page 5 / 5
6 U.S. Federal Regulations SARA 313 This product is not regulated by SARA. Clean Air Act, Section 112 Hazardous Air Pollutants (HAPs) (see 40 CFR 61) This product does not contain HAPs. U.S. State Regulations California Proposition 65 This product does not contain chemicals listed under Proposition 65 WHMIS hazard class: D2A Very Toxic Materials This product has been classified according to the hazard criteria of the CPR and the SDS contains all of the information required by the CPR 16. Other information For Research Use Only. Not intended for human or animal diagnostic or therapeutic uses. The above information was acquired by diligent search and/or investigation and the recommendations are based on prudent application of professional judgment. The information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may present unknown hazards and should be used with caution. Since the Company cannot control the actual methods, volumes, or conditions of use, American BioInnovations, LLC shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS SDS DOES NOT CONSTITUTE A WARRENTY, EXPRESSED OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY PARTICULAR PUPOSE. End of Safety Data Sheet Page 6 / 5
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