High power (600W) 808nm diode. Shall We THE Tango? Perfect Solution for Permanent Hair Removal

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Dustin Lester
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1 High power (600W) 808nm diode Shall We THE Tango? Perfect Solution for Permanent Hair Removal

2 MAIN CLINICAL INDICATION BY THE TANGO Skin Tightening Hair Removal Acne Treatment

3 ANATOMY OF HAIR SHAFT Surrounded by an outer and inner sheath Shaft composed of 3 layers Cuticle: outer layer Cortex: middle layer Medulla: inner layer

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5 HAIR DENSITY 5 million follicles 100, ,000 on the scalp Birth: 1135/cm 2 1 year: 795/cm : 615/cm : 485/cm : 435/cm 2

6 HAIR GROWTH CYCLE Stages Anagen = growth Catagen = involution Telogen = rest Anagen - Growth Phase 1000 days (or more) Catagen - Transitional phase 10 days Telogen - Resting Phase 100 days

7 Anagen - Growth Phase 1000 days (or more) Catagen - Transitional phase 10 days Telogen - Resting Phase 100 days 7

ANAGEN Active stage Germ cells begin to multiply by mitosis Before follicle reaches full depth, cells in the lower part of bulb become active moving upward to become cells that Produce the hair

8 ANAGEN Active stage Germ cells begin to multiply by mitosis Before follicle reaches full depth, cells in the lower part of bulb become active moving upward to become cells that Produce the hair Produce the inner root sheath Melanin production increases to give the hair its color In late anagen, melanin production stops and pigment at the base of the hair shaft becomes thinner and lighter

9 CATAGEN This stage follows anagen Club hair is formed when dermal papilla separates from hair matrix and hair begins to rise in follicle. Hair is held in follicles by the inner root sheath Hair becomes drier and follicle begins to shrink and collapse below the rising hair

TELOGEN Final stage of growth that follows on from Catagen Is also known as the resting phase Follicle is inactive until stimulated to move into anagen and start

10 TELOGEN Final stage of growth that follows on from Catagen Is also known as the resting phase Follicle is inactive until stimulated to move into anagen and start process over again Club hair often remains in follicle until pushed up and out by new forming hair Depth of telogen follicle approximately 1/3 rd of anagen follicle

11 HAIR GROWTH CYCLE(I) Area Resting phase(%) Growth Phase(%) Hair growth cycle times Growth Phase Resting Phase Scalp months 2-6 year Beard week 1 year Axilla months 4 months Bikini Line months 4 months Upper limbs (Arms) Lower limbs (Legs) week 13 weeks week 16 weeks Breast

12 HAIR GROWTH CYCLE (II) Normal scalp activity Anagen = 85-95% Catagen = <1% Telogen = 5-10% At the end of telogen, hair is released and the next cycle is initiated Up to 100 hairs in telogen are shed each day and about the same number of follicles enter anagen

13 THE SCIENCE & HISTORY OF HAIR REMOVAL

14 The History of Hair Removal Diode 808nm Alexandrite 755nm Light based sources Q-Switched Nd:YAG 1064nm Ruby 694nm

15 DIODE LASER NM The Diode Laser consisting of a high power laser diode emitting infrared (invisible) light at nm The longer wavelength allows deep penetration into the skin and safety for darker skin types

16 ALEX LASER 755 NM The Alexandrite Laser produces reddish light just at the limit of visibility at 755nm With its large (up to 18mm) spot size and high repetition rate, the Alexandrite laser is suitable for patient with light to olive complexion

17 IPL NM IPL devices Treatment of darker skin types is less effective and more risky than with a laser properly selected for the patient's skin and hair type

18 ND:YAG LASER 1064 NM The long pulse Nd:Yag laser is the "newest" hair removal laser Ideal for dark skin type hair removal Disadvantages include more discomfort during treatment and less effective clearance for fine and light hairs than the other hair removal lasers

19 RUBY LASER 694NM The Ruby Laser is the "original " hair removal laser However, because melanin is present in the skin as well, the Ruby laser cannot be used on patients with darker skin, including tanned skin

20 THE THEORY OF SELECTIVE PHOTOTHERMOLYSIS

21 The Science of Hair Removal (I) The mechanism of laser epilation involves the absorption of laser light by the pigment melanin The melanocytes of the hair bulb and the melanin in the hair shaft heat up due to exposure of the laser light, as a result of which the hair follicle is damaged

22 The Science of Hair Removal (II) Long pulses lead to heat diffusion from the bulb to the area of the bulge and he matrix cells, leading to destruction of the capacity for new hair follicle formation, and this leads to long- lasting results The higher the melanin absorption the better the effect

23 The Science of Hair Removal(III) The efficacy of the treatment is influenced by the following factors: Skin color Hair color Hair thickness Depth of the hair in the skin

24 Fitzpatrick Skin Types Caucasian, European : skin type I, II Eastern Asian, American Indian: skin type III, IV Middle Eastern, Mediterranean, Hispanics, Afro-American : skin type IV, V African descent : skin type V

25 HAIR COLOR Dark hair - Black or dark brown ; Allows laser light to be absorbed to a greater extent Medium hair - Light or medium brown ; Easier to treat than lighter hair colors Light hair - Less able to absorb the laser light ; The most difficult to treat & require more procedures White or grey hair - No absorption laser light ; Almost impossible to treat

26 EXTERNAL FACTORS Tanning or Sun exposure ; Harder for laser light to pass through the skin Herpes History of scarring

27 TIPS FOR HAIR REMOVAL The Bulge cells are multifunctional and give birth to a new follicle after each catagen phase. Consequently, during the telogen phase, the area under the Bulge destroys itself The new follicle is generated notably from the permanent germ cells of the bulge. To create permanent hair removal the germ cells in the bulge must be destroyed

28 The bulge is a highly vascular area We can use 808nm diode to target blood BUT TIPS FOR HAIR REMOVAL (II) The light must be delivered quickly Blood is a moving target If we pour the energy in too slow, it just gets carried away before the target reaches the right temperature to create damage

29 The laser energy is absorbed by the melanin in the hair follicle The hair s bulb, papilla and bulge areas are heated The surrounding tissue remains unaffected 29

30 Selective photothermolysis Selective absorption of hair chromophores, melanin, from laser and broad band light sources results in destruction of hair follicles while leaving the skin undamaged

31 LASER HAIR REMOVAL BY 808 DIODE HIGH POWER THE TANGO

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33 Why is ms the Ideal for Hair Removal? Hair follicle TRT : ms Epidermis will no longer contain the heat energy but will begin to diffuse it between ms after the application of energy If the pulse width is shoter than the TRT of the follicle, hair follicle cannot be destroyed THE Tango pulse width is closest to the Follicle TRT Epidermal Melanin TRT Follicle TRT 3ms 7ms 10ms 100ms <Thermal Relaxation Time>

34 LASER APPLICATIONS DURING 20 TO 100 MS Pulse width must be the same as the time of TRT of Hair FOLLICLE ( 20 to 100 ms) 34

35 Deeper Penetration Depth for Hair Follicles Ideal for Hair Removal with 808nm Wavelengths 808

Hair Removal with high power THE Tango ( 808 diode Laser) They use melanin in hair shaft as a Chromophore to absorb the light and heat bulb Heat Germ cells to

36 Hair Removal with high power THE Tango ( 808 diode Laser) They use melanin in hair shaft as a Chromophore to absorb the light and heat bulb Heat Germ cells to 45 to 65 degrees After absorbing the energy of laser, the hair follicles and relevant structure are damaged so as to break the survival environment of the hair

37 Mechanism of Hair Reduction by THE Tango Light Energy Absorbed Heating Destroyed Hair Follicles Unable to Regrowth

38 New Approach Hair removal By THE Tango

39 THE Tango hair removal system Target : Melanin in hairs in the anagen phase Action : Destruction of the hair follicle

40 THE Tango hair removal system Hair follicle must be present Good result: Erythema and edema around follicle, burning of hair Bad result: Blanching or graying of skin Facial hair: Usually requires 5-6 treatments (chin and upper lip) repeated at 4 week intervals Body hair: Repeated at 6-8 week intervals 60-95% removal at 6 months. Regrowth usually finer and lighter

41 SAPPHIRE COOLING HANDPIECE (I) Spot size (12 x 10 mm) Adjustable high pulse repetition rate (Up to 20Hz) Sapphire contact cooling

42 Sapphire cooling handpiece (II) SAFETY + EFFECTIVENESS Handpice material very conductive to give a good distribution of cooling ( good protection of epidermis) Allowing constant cooling during the treatment Allowing higher fluences for any skin types Increases patient comfort

43 THE TANGO TECHNOLOGY Healux new approach of applying the energy the energy at a high repetition rate (20hz) while les than 20mJ ( using higher average power (100W) and lower flueence ( 5mJ-20mJ) to insure gradual heating of area take places to reduce discomfort. Virtually pain free hair removal Gradual thermal rise to the target s temperature without being the risk of injury and with less pain for the patient The sweeping technique of ( Circular Pattern/ Pain-brush Pattern) In a larger treatment area for increasing comfort for patient 43

44 FAST MOVING MODE FOR PAIN FREE TX Fluence : 5mJ- 20mJ Mode: Fast Moving Mode Repetition: up to 20 Hz Pattern: Circular pattern/ painbrush pattern Short pulse with high repetition rate enable to give patient less pain free treatment 44

45 PERFECT SOLUTION FOR BRAZILIAN HAIR REMOVAL Why we are going to high power for Brazilian hair removal? The most power Diode laser 45

46 THE FUTURES OF THE TANGO 808nm Laser Supporting High Power Diode Laser (600W) Available for various diseases for which medicine is efficacious More powerful double cooling function Multifunctional diode laser equipment with applicable to all kinds of skin types even dark skin types Main indications : Hair Removal Skin Tightening Whitening Wrinkle Acne Scar Acne Treatment Smoothing

47 THE HIGHLIGHT OF THE TANGO (I) Fast treatment : one of the fastest of the market spot size 12x 20 Hz Powerful device : 600W higher power diode In- motion mode : 1-20 mj with 20 Hz ( short pulse)- painless treatment No consumables Comfortable treatment ( the coldest tip in the market) Treating all skin of type even dark skin ype 47

48 THE TANGO HAIR REMOVAL SYSTEM Providing permanent hair reduction using state-ofthe-art, high power (600w)laser technology Fluences up to 120 J/cm 2 Pulses from 2.5 to 700 ms. Fast Moving mode :up to 20 Hz Enables predictable, reliable and reproductive results

49 THE TANGO SPECIFICATIONS Light Source Wavelength Fluence Power on Tissue Pulse Duration Spot Size Repetition Rate Fast Mode Normal mode Delivery Skin Cooling Electrical Requirements Physical Dimensions Platform Weight Diode,Continuous Wave 808 nm Up to 120 J/cm 2 600W ms 10X14 mm Up to 20 Hz Up to 10 Hz Sapphire tip contact 5 water chill cooling Standard 230 VAC 450 x 500x 275 mm 50Kg

50 FEATURES OF THE TANGO SYSTEM Fastest laser hair removal - up to 20Hz Reliable results Safe and effective - the Unique Blend Mode provides a sage and effective way for treating patients with any skin type. Treats all types of hair Powerful gold standard diode treatment head(up to 120J/cm 2 ) allows treatment of any type of hair.

51 FEATURES OF THE TANGO SYSTEM Simple to use Increased patient comfort Increased profitability Cost effective Easy to use

52 MODELS OF THE TANGO

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55 SHORT PULSE & LONG PULSE 55

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57 T 1 ( Delivery Pulse) Mode by THE Tango Use for thick and dark hair Adjustable pulse type as any skin type Fluence : 1-120/cm2 Fluence Step: 2 J/cm2 Pulse Repetition Rate: 1-10 Hz Pulse Type: Short, Long, Burst, Blend Short Long Burst Blend

58 T 1 ( Delivery Pulse) Mode by THE Tango SHORT PULSE TYPE Basic pulse type used 600watt full power Use for all hair types with Skin type III

59 T 1 ( Delivery Pulse) Mode by THE Tango LONG PULSE TYPE Half-power and two times greater than the pulse duration of the Short Pulse Use for thick hair with dark skin type

60 T 1 ( Delivery Pulse) Mode by THE Tango BLAND PULSE TYPE Combinations of longer pre-heating pulse with short pulse Incremental fluence for effective treatment Optimized pulses for each skin type

61 T 1 ( Delivery Pulse) Mode by THE Tango BURST PULSE TYPE Divided to three short pulse On Time: Short x 1/3 Off Time: Short x 1/6 Use for all hair types with dark skin type ON time OFF time 6J 6J 6J

62 T2 ( Delivery Pulse) Mode by THE Tango Use for thin hair Adjustable pulse type as any skin type Fluence : 5-28J/cm2 Fluence Step: 1 J/cm2 Pulse Count: 1 to 7 (1 Step) PRP: 1-2 Hz OFF Time: 5 ms

method Fluence is set at the low energy because of overlapping shot Fluence :

63 FM mode ( Fast Moving Mode) by THE Tango Concept with the rapid moving method on enlarge area to delivery the energy faster Use for pre-heating the skin in moving method Fluence is set at the low energy because of overlapping shot Fluence : 1-24J/cm2 Fluence Step: 1 J/cm2 Pulse Repetition Rate: 10 to 20Hz Short shot (fixed)

64 CW (CONTINUOUS WAVE) MODE BY THE TANGO New acne treatment method to reduce sebaceous gland activity and remove acne Provide PDT treatment with ICG (Indocyanine green) Fluence : 1 to 20 W Fluence Step: 1 W Frequency (Hz): 10 to 100 Hz Time: 5 to 10 min

65 ACNE TREATMENT BY THE TAMGO 65

66 CONTINUES WAVE MODE- ACNE TREATMENT Apply the Indocyanine green on the treatment area Do not contact the handpiece to the skin surface Move the handpiece 1 cm away from the skin surface

67 TREATMENT GUIDE FOR THE TANGO Area MODE FLUENCE [J/cm²] PRR [Hz] PULSE CNT PULSE TYPE Pass Note Armpit Thick FDP SHORT 6 DP I BLEND 1 FDP + DP I Bikini Line Thick FDP SHORT 6 DP I BLEND 1 FDP + DP I Upper Limb & Lower Limb (Woman) Upper Limb & Lower Limb (Man) Upper Lip Forehead Thin DP I SHORT 2 Thick DP I SHORT 2 Thick DP I SHORT 2 Thin DP II SHORT 2-3 Thick DP I SHORT 2-3 Side Burns (Man) Thick DP I SHORT 2

68 AREAS OF HAIR REMOVAL

69 THE Tango treatment Procedure Step I Cleanse the treatment area completely Step II Apply the gel on the treatment area Step III Contact the handpiece fully on the skin Step IV Move the handpiece perpendicularly

70 THE PREPARATION OF THE TANGO Step I Shave the treatment area one day before treatment Step II Not use depilatory, bleach or wax for up to 2 weeks before treatment Step III No tanning within 2 weeks before laser treatment

71 WHAT TO EXPECT? Erythema or redness Blistering in dark-skinned or tanned skin Changed skin color

72 WHAT TO EXPECT? Hair shafts may extrude during the 2-3 weeks following treatment May simply be shaved or plucked Hypo and Hyper pigmentation Change of skin texture Crusting and Scabbing Hair change ( fine and lighter)

73 Easy Post Treatment Care Immediate after Applying cooling pack For the day Any baths & saunas should be banned For one week Do not expose to sunlight & wear sunblock over SPF 25 For 48 hours Do not use cosmetics including alcohol

74 POSSIBLE SIDE EFFECTS Skin pigmentary change Blisters with fair skin Burns with dark skin Scars Note : Those side effects are very rare!

75 ADVANTAGES OF THE TANGO Non-invasive method for hair removal Safe Painless treatment using FM mode Long-lasting hair removal Permanent hair reduction Useful for large areas (backs or legs) High power diode laser used

76 POST CARE AFTER THE TANGO Minimal use of makeup and maximum use of moisturizer Use sun block of SPF 25 or more If needed, the only other acceptable hair removal method during the treatment regimen is shaving Be aware that hair will continue to shed up to three weeks after the treatment

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83 COMPETITOR ANALYSIS ( HAIR REMOVAL LASER) Technology Fluence Pulse duration Alma SopranoXL Diode810nm + NIR Up to 120J/cm2 Asclepion MediostarXT Diode810nm + 940nm Up to 90J/cm2 Lumenis Lightsheer Diode800nm Syneron elaser Diode810nm + RF J/cm2 Up to 50J/cm2 MedArt A/S MedArt435 Diode810nm Up to 200J/cm2 Lasering VelureS800 Diode808nm J/cm ms 5-500ms 5-400ms Short / Long ms ms Spot Size 12X10mm 4,6,10,12,14 mm 12mm 12x15mm 1.2,2.5,4,8 mm 2.5,4,8,12 mm Rep Rate Up to 10Hz 0.5-4Hz Up to 2Hz Up to 2Hz Up to 100Hz 0.5-5Hz Cooling Contact cooling Skin cooling Chilled tip Skin cooling Skin cooling Air cooling

84 ASCLEPION MEDIOSTARXT Asclepion MediostarXT Technology Fluence Pulse duration Spot Size Rep Rate Cooling Diode810nm + 940nm Up to 90J/cm ms 4,6,10,12,14mm 0.5-4Hz Skin cooling Distributor

85 LUMENIS LIGHTSHEER Lumenis Lightsheer Technology Fluence Pulse duration Diode800nm J/cm ms Spot Size Rep Rate Cooling 12mm Up to 2Hz Chilled tip Distributor

86 Syneron elaser Syneron elaser Technology Fluence Pulse duration Diode810nm + RF Up to 50J/cm2 Short / Long Spot Size Rep Rate Cooling 12x15mm Up to 2Hz Skin cooling Distributor

87 Syneron elaser Technology Fluence Pulse duration Spot Size Rep Rate Cooling MedArt A/S MedArt435 Diode810nm Up to 200J/cm ms 1.2,2.5,4,8 mm Up to 100Hz Skin cooling Distributor

88 LASERING VELURE S800 Lasering VelureS800 Technology Fluence Pulse duration Diode808nm J/cm ms Spot Size Rep Rate Cooling 2.5,4,8,12 mm 0.5-5Hz Air cooling Distributor

89 Hair free life with THE Tango (808nm) 89

90 Shall we THE Tango?

OLIVE. Top Hair Removal Diode Laser System

OLIVE. Top Hair Removal Diode Laser System OLIVE Top Hair Removal Diode Laser System 1 1.Olive Laser? Using the 810nm pulse diode laser, OLIVE destroys the black melanin pigments in the hair follicle to remove hair. The beam of Olive provides identical