Innovation in Skin Regeneration

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1 MICRO-NEEDLING

2 MICRO-NEEDLING The technique of micro-needling Indications : The technique of «micro-needling» is well known for its dual cell stimulation: biophysics and mechanized and chemical. It has already proven itself well and is widely used. The modernized this technique. Acne and surgical scars. Skin slackening. Radiance booster. Dermal remodeling. Fine lines and wrinkles. Enlarged pores. Stretch marks. Alopecia. This technique consists in creating multiple micro-perforations in the skin, creating channels up to the dermis. It permits the stimulation of fibroblasts for a natural activation of the synthesis of collagen and elastin fibers; thus natural cell regeneration is accelerated. It is called biophysical stimulation (mechanical) or CIT (Collagen Induction Therapy). Thanks to the created microchannels, the penetration of active ingredients (vitamin cocktails, noncrosslinked HA, Amino Acids, etc.) in the skin is facilitated. We speak of chemical stimulation. Laboderm laboratories advise to work in optimal asepsis conditions. The Dermanov Kit, cosmetic set for single use, is recommended for this purpose (ref ). This kit contains: 1 charlotte, 1 plastic table field no holes 38 x 45 cm, 10 non-woven compresses 10 x 10 cm, 3 balls nonwoven 1 hard blister 3 compartments. Effects of biophysical stimulation 1 - Vertical penetration and atraumatic needles of Effects of chemical stimulation 1 - Penetration of active ingredients (A.I.) 2-R egeneration of the skin by activating the synthesis of elastin and collagen fibers. 2 - Penetration of active ingredients through the A.I. A.I. Epidermis Microwoudnds create e by the ultra-fin needles. Dermis Fibroblast stimulation. Elastin Fibroblasts Collagen Hypodermis Easier absorption

3 SETTING Tip with multiple vertical needles of 33G. 3 types of tips available. 4 Lightweight and ergonomic.. Comfortable grip for the practitioner. utra-fine needles 33G 2 Simple use tip : economical. Compared to the price of a conventional roller. 5 Allows treatment in difficult access areas. (Eg : Nose contour, upper lip, etc. ). 3 Penetration depth of the needles can be adjusted up to 2mm. Fine adjustment of 0,2 mm by 0,2 mm. 6 Adjustment of the speed in 4 stages.. A modular device : The penetration depth of the needles may be adjusted depending on the treatement areas. By adjusting the penetration depth of the needles, allows both gentle and more intensive care. It adapts to the tolerances and / or the patient s request. The penetration speed can be adjusted. For best results and a better user experience, it is advisable to work at maximum speed With one tip the allows a full face, a neck and neckline treatment. is a device Class IIa. Its use is only for health professionals.

4 Depth (mm) of penetration of the needles depending on the treated area. THE PROTOCOL By LABODERM Stretch marks : 2,0~2,5 mm Scars : 1,5~2,5 mm 0,25~0,5 0,7 0,25 0,25 0,5~1,0 0,5~1,0 0,8~1,5 0,8~1,5 0,25~0,5 0,5~1,0 9 needles round Tip for all areas Needles 9 linear needles Tip for linear stretch marks and scars. 3 needles round Tip for ice pick scars and targeted areas Treatment consists of around 4 sessions every 4 to 5 weeks, what neo-collagenesis cycle corresponds. STEP 1: Skin Preparation Remove the make-up, clean the area to be treated and disinfect, etc. A scrub may be performed beforehand. STEP 2: Anesthesia of the treatment area for comfort Anesthetize the area to be treated with an anesthetic cream before the procedure. Anesthesia is appreciated by the practitioner according to the depth used on the treatment area. STEP 3: Application of the active ingredients Spread the cocktail (AH, amino acids, vitamin cocktails, etc.) on the surface to be treated before starting treatment. STEP 4: The treatment Perform several passages with on the area being treated to obtain an optimal stimulation. After treatment it is recommended to apply moisturizing mask PROCARE highly concentrated in AH.. STEP 5: Post Act To reduce redness and accelerate wound healing, spend Balm MORAZ, highly concentrated in Polygonum, on the treated area. Redness and suites observed in Post-Act are directly related to the type of treated skin, desired results and depth of used needles. Eg : For a treatment performed with a depth of 0.5 and 1 mm, the redness will last 1-2 days. From 1 mm depth, slight bleeding may arise. Side effects The side effects are simple and non-specific. The treatment leaves a pink face. Redness disappear within 48 hours; in the case of deeper treatment, redness may last for up to 5 days. The micro-traumas can be hidden by a corrective foundation. There is no socio-professional eviction. Additional treatments The may be associated with the LEDs therapy in order to enhance the tissue regeneration process and potentiate the effects. Also peels can be performed in conjunction with treatment.

5 & ACTIVE INGREDIENTS EL OA EXT RA C L-PROLINE LU LA R M ATRIX C OM HYALURONIC ACID TS A MIN GLYLICINE L L-LEUCINE L-LYSINE GIVES PULSE TO THE METABOLIC ACTIVITY OF FIBROBLASTS, STIMULATING PRODUCTION AND ENCOURAGING THE SYNTHESIS OF NEW COLLAGEN. ENSURE MAINTAINING OPTIMUM MOISTURE LEVELS AND CREATE SCAFFOLDING MOLECULAR THAT MAKES THE SKIN MORE ELASTIC. COLLAGEN BOOSTER Composition of Jalupro to restore: 1 vial of 100 mg lyophilized amino acids 1 sterile vial of 30 mg / 3 ml of non-crosslinked hyaluronic acid Hypertrophic scars of acne* Skin slackening** Neck and neckline** Before Before Before After After After *Dr HAZIZA Jean-Luc, Dermatologist, France **Dr DANZA Daria, Dermatologist, Russia N EN restores radiance and firmness to dull skin, improves the appearance of scars, keloids and stretch marks. Prevents and reduces the signs of skin aging. U N C TI O N A T ER Easy and fast treatment. Portable equipment. Visible results after the first session. Attractive price. Sterile and single use tips for maximum safety! No social eviction. No dependent skin phototype. DF US CI PO THE SKIN BIOREVITALIZATION PATENTED FORMULA CL Benefits of micro-needling: is a unique combination of a high concentration of acid uncrosslinked hyaluronic and a complex of amino acids, essential elements the formation of collagen and elastin fibers.

6 SUITABLE FOR ANY SKIN PHOTOTYPE Tightening Scars Alopecia Stretch marks Skin tonicity Radiance booster Acne Skin slackening Anti-aging Mesolift Export Dpt : +33 (0) international@laboderm.fr Laboderm - ZA CDG -14 rue Ferdinand de Lesseps - F Goussainville LAB vol ANG Plaq Med EsteticPen - Fait en novembre Imp. Peau Wrinkles Enlarged pores

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