Problem skin range.

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1 Problem skin range

2 Problem skin Propionibacterium acnes is the bacteria responsible for inflamed acne breakouts. It is generally harmless but when pores become engorged with excess oil and dead skin cells, it creates an environment where P. acnes can excessively grow. This then triggers inflammation within the pore, creating a papule, pimple, or cyst. Reducing the P. acnes population is therefore an important step in controlling acne. Teenagers and adults are often very selfconscious when skin breaks out, either as a result of acne and skin inflammation. Fortunately the cosmetics industry offers a number of ingredients to prevent, treat and target problematic skin. Infinity Ingredients is proud to summarise the materials we offer for this category below.

3 Anti-bacterial For a comprehensive list please refer to our Preservative and Anti-bacterial range leaflet. Canadian Willowherb (INCI: Water (and) Epilobium Angustifolium Flower/Leaf/ Stem Extract) is an edible (used in tea bags) multifunctional active ingredient that contains bioactive molecules such as Oenothein B which has 5-α-reductase inhibitory activity, anti-oxidant and anti-bacterial properties. Its primary function is as a non-steroidal anti-irritant ingredient. In vitro experiments have demonstrated free radical scavenging ability. In addition, Canadian Willowherb shows strong anti-bacterial activity on P. acnes. Its anti-irritant and redness reduction properties have been clinically demonstrated, showing a strong reduction of skin redness induced by chemicals or UV exposure within 30 minutes of use. Ideal for anti-acne, redness, anti-ageing, intimate care, oral care (anti-irritant/ bleeding gums), sun care (reduces UV-induced erythema) and baby care (nappy rash). Recommended use level: 1-3% CYTOFRUIT WATERS Lemon (INCI: Citrus Limon Fruit Extract) is an organic certified water from Lemon fruits harvested in Mediterranean organic fields. Rich in Vitamin C, Potassium and Citric Acid, Lemon fruits cleanse and exfoliate dull and oily skins, whilst refreshing and quenching the skin s thirst to provide a radiant glow. In addition, Lemon fruit also offers natural anti-bacterial and astringent properties. Thanks to the presence of oligo-elements, this CYTOFRUIT Water could sustain skin biological benefits through an improvement of cell vitality, a protection against external agents or a physiological improvement. Standard grade (Bio 99) is preserved with Potassium Sorbate. Bio grade is available and is preservative-free. Recommended usage level: 1 100% Dermosoft Decalact (INCI: Sodium Caproyl/Lauroyl Lactyl Lactate) is a natural and effective active (from sugar beet) against gram positive bacteria and yeasts with efficacy against Melassezia Furfur (dandruff), Trichophyton (athletes foot), Candida Albicans (thrush) and P.acnes (acne). For dandruff applications the optimum ph is 5.5, which is lower than the more traditionally used Octypirox (ph 7). The optimum ph for a healthy scalp is 5.5. Upon testing, Decalact was found to outperform Climbazole and Triclosan in treatments for Athletes Foot. Decalact is also effective in nail care. In thrush treatments, Decalact was found to immediately reduce Candida Albicans. For acne, Decalact was found to perform comparably to 0.5% Salicylic Acid. There are no usage restrictions for Decalact. Easy to handle version is Dermosoft Decalact Liquid. Recommended use level: 0.5 1% (leave-on) and 1 2% (rinse-off). Drieline (INCI: Sorbitol (and) Yeast Extract) is a highly purified Yeast Polysaccharide extracted from Saccharomyces cerevisiae. This Yeast, used in a multitude of common fermentation processes (beer, alcohol, bread) reinforces the natural skin defence system as well as cell renewal. The Polysaccharide is obtained by an eco-friendly manufacturing process. Ideal for anti-aging and antimicrobial applications as well as the protection of Langerhan cells which are not protected by Melanin. Recommended use level: 0.5-2% HydroSal BKC (INCI: Water, Polyvinyl Alcohol, Benzalkonium Chloride, Ethyl Alcohol, Phenoxyethanol, Ethylhexylglycerin, Acrylates Copolymer). BKC (Benzalkonium Chloride) extends protection from microbes, pathogens, bacteria, viruses, fungi, and protozoa. It has consistently been the disinfectant of choice for hospitals. HydroSal BKC was designed to achieve a better utilisation of BKC, while replacing alcohol-based antiseptics, at low concentration. HydroSal BKC is an encapsulation technology comprised of sub-micron spheres approximately 0.1 to 0.3 microns in diameter. These spheres are infused with BKC and form a clear product. The HydroSal technology allows for time release and longerlasting effects, extending the time of protection from microbes. The product is effective upon application. In addition, it can be re-activated long after initial application, when exposed to water or perspiration. The shell is able to assemble and lock in the BKC while drying. Once in contact with water after drying out, the shell dissolves and exposes the BKC again. This feature allows the system to provide maximum protection in areas that are exposed to cycles of dampness and dryness. The protection is needed most in damp/wet conditions because these conditions are favourable for bacteria growth, such as the under arm and foot. Suitable for sanitisers, disinfectants, anti-acne applications such as lotions and sprays, mouth washes and cleansers. Recommended inclusion level: %

4 Greasy skin CITROMAT (INCI: Citrus Aurantium Dulcis Fruit Powder, Citrus Grandis Peel Powder, Citrus Medica Limonum Fruit Powder) is made from the peel and pulp of citrus fruits and has the appearance of a vegetable talc; the surface of each particle being fine and regular, almost spherical micro bead. It delivers a micro-smoothing and oil-absorbent effects: the fineness and regularity of the particles allow a very precise and non-aggressive exfoliation, while also absorbing excess sebum. Using CITROMAT gives back the skin its natural radiance, with a perfect velvety and an oil-free aspect. Recommended use level: 5-15% CYTOFRUIT WATERS Grapefruit (INCI: Citrus Grandis Fruit Extract) is an organic certified water from Grapefruit fruits harvested in Mediterranean organic fields. Rich in bioflavanoids, Grapefruit provides detoxifying and antioxidant properties, whilst improving cell energy levels for anti-ageing benefits. Ideal for skin toning, anti-cellulite, detoxifying and oily skin. Thanks to the presence of oligo-elements, this CYTOFRUIT Water could sustain skin biological benefits through an improvement of cell vitality, a protection against external agents or a physiological improvement. Standard grade (Bio 99) is preserved with Potassium Sorbate. Bio grade is available and is preservative-free. Recommended usage level: 1 100% Dermosoft Decalact Sebum (INCI: Polyglyceryl-10 Laurate, Sodium Caproyl/Lauroyl Lactylate, Glycerin, Serenoa Serrulata Fruit Extract, Juniperus Communis Fruit Extract) Multi talented natural active ingredient blend fighting the signs of blemish prone skin. In-vivo proven efficacy for reduction of sebum production, redness and pimples at a low dosage. Suitable for certified natural cosmetics. Recommended inclusion level: 2% ENNACOMPLEX 264 (INCI: Aqua, Propylene Glycol, Arctium Lappa Root Extract, Citrus Medica Limonum Fruit Extract, Hedera Helix Leaf Extract, Nasturtium Officinale Leaf Extract, Salvia Officinalis Leaf Extract, Saponaria Officinalis Leaf Extract) is a botanical complex for the care of oily/greasy skin with blemish problems. A blend of extracts of Burdock root, Sage leaf, Watercress leaf, Lemon fruit, Soapwort herb and Ivy leaf, ENNACOMPLEX 264 can help tighten pores, regulate sebum production, and alleviate bacterial proliferation on the skin. Recommended use level: 1-10% ENNACOMPLEX 273 (INCI: Aqua, Propylene Glycol, Hamamelis Virginiana Extract, Pyrus Malus Leaf Extract, Quercus Robur Extract, Rosa Centifolia Extract) is a botanical complex particularly rich in tannins; compounds known for their astringent, antipruriginous, anti-inflammatory, antiseptic, and antiseborrheic properties. The product tightens open pores, reduce sebaceous secretions and inflammation, and heal small cuts and blemishes. It is thus especially intended to formulate preparations for the care of greasy skin with open pores, and acne prone skin with blemish problems. The ENNACOMPLEX 273 can also be used in aftershaves and after depilatory products. The product contains a balance blend of Hamamelis leaf, Oak bark, Apple leaf, and Rose flower extracts. Recommended use level: 3 12% ENNACOMPLEX 267 (INCI: Aqua, Propylene Glycol, Arctium Lappa Root Extract, Calendula Officinalis Extract, Citrus Medica Limonum Fruit Extract, Humulus Lupulus Extract, Hypericum Perforatum Extract, Salvia Officinalis Leaf Extract, Saponaria Officinalis Leaf Extract) is a botanical complex for the care of young skin having tendency to acne, oily and blemish problems. ENNACOMPLEX 267 contains extracts of Burdock root, Lemon fruit, Hops cone, Saint John s Wort flower, Sage leaf, Marigold flower and Soapwort herb to synergistically tackle the causes and effects of problematic skin. Recommended use level: 3-10% GREEN CLAY (INCI: Illite) is an Illite-type clay extracted in France and naturally dried under the sun. GREEN CLAY is a natural ingredient intended to prepare creams, pastes, masks, body wraps and bath products for skin and hair care. GREEN CLAY is known to be softening, purifying and soothing. It tones and lightens the complexion and can be particularly dedicated to the treatment of oily or acneprone skin. Recommended use level: 1-25%

5 INKA AKECH (INCI: Propanediol (and) Water (and) Schkuhria Pinnata Extract) is an exclusive ingredient to 3QP from the Canchalagua native to the Andean region. Traditionally used for the treatment of oily skin and skin problems caused by oily skin and toxins such as dermatitis, eczema and acne. It also provides defense against cellular oxidation and collagen degradation, protecting oily skin from premature ageing. Ideal for oily skins prone to blackheads and acne, as well as greasy hair. Recommended use level: 1 10% Matipure Oil Free (INCI: Magnesium Aluminium Silicate (and) Hydroxy- Ethylcellulose (and) Phospholipids). A unique patented biocompatible complex characterised by highly adsorbent porous micro particles made of Cellulose Magnesium Silicate complexed Phospholipids. When Matipure is applied on the surface of the skin, water slowly evaporates allowing excess sebum to gradually migrate inside particles, providing an immediate matifying (reduces sebum by 40% after 1 hour) and purifying effect. Phospholipids give smoothness to the skin and avoid a drying effect. Recommended use level: 1-5% MultiSal Sebum Control (Sodium Starch Octenylsuccinate, Hydrated Silicam, Acrylates Copolymer, Sodium Hydroxide, Zinc Sulfate, Butyrospermum Parkii (Shea) Butter, Lauryl Laurate). MultiSal Sebum Control is a microencapsulation technology that provides immediate and long-lasting absorption of excess sebum as well as long-term maintenance of sebum production. MultiSal Sebum Control is highly effective in reducing shine on skin, resulting in a healthy-looking matte finish that is conducive of blemish-free skin. Ideal for skin care applications such as lotions, body powders, acne spot treatments, and facial wipes. Recommended use level: 3-5% foam. Non-comedogenic. Suitable for emulsions, body care, sticks, mascaras, shampoo, hair masks, colour foundation, lip gloss, sun care, wet wipes, liquid soap and bar soap. Recommended use level: % Specifeel NH Butters: Argan (INCI: Argania Spinosa Kernal Oil, Palmitic/Stearic Triglyceride). Specifeel NH Butters are nonhydrogenated, stable and unique butters. The Argan Tree contains lipid components that possess a remarkable ability to nourish, moisturise and improve skin elasticity. Rich in Lipids (Omega-9 and 6), Polyphenols (anti-oxidant and stability benefits), natural Tocopherols (Vitamin E), Carotenes, Squalene, Essential Fatty Acids and Vitamins. Argan is used to help fight ageing through elasticity and hydration, and is most often used in hair, nail, face and body. When applied to dry and damaged skins it can assist in ph balance and sebum regulation and protect against external aggressions (sun, heat). Recommended usage level: 3-40% Specifeel NH Butters: Black Cumin (INCI: Nigella Sativa Seed Oil, Palmitic/Stearic Triglyceride). Specifeel NH Butters are nonhydrogenated, stable and unique butters. Black Cumin is the seed of blessing of ancient Arabic civilisation that shows many beneficial effects (antioxidant, antiseptic, aphrodisiac, depuritive plant). Used in masks and cream dedicated to oily skins, its cleansing properties make it an interesting skin stimulant. Rich in tannins, this tonifying plant is ideal to spice up the skin with reinforcing strength. Recommended usage level: 3-40% Olifeel TD7525 (INCI: Olive Glycerides) is a unique synergy of highly purified olive triglycerides and diglycerides with a soft, non-greasy touch. Benefits include higher skin penetration due to the biocompatibile triglycerides, increased stability due to polar diglycerides as well as an enhanced resistance to oxidation. Highly stable and good for producing shower creams with moisturisation claims. Triglycerides remain on the skin providing a caring and moisturised effect. Does not impact on

6 Inflammation Abyssine (INCI: Water (and) Butylene Glycol (and) Alteromonas Ferment Extract) from the deepest oceans Abyssine is a real survival molecule that reduces skin reactivity and discomfort as well as providing protection against UV-damage, allergic reactions and mosquito bites (anti-histamine treatment). Abyssine also soothes irritated and sun burnt skin making it the ideal option for the protection of sensitive and itchy skin. Lastly for acne patients taking Retinol drugs Abyssine reduces skin discomfort, dryness and flakeyness. Recommended use level: 0.5-5% Aldavine & Aldavine 5x (INCI: Water (and) Sorbitol (and) Ascophyllum Nodosum Extract (and) Asparagopsis Armata Extract) is a highly potent cosmetic active ingredient from the calibrated association of 2 unique algae Polysaccharides. Aldavine effectively targets pro-inflammatory mediators and MMPs to protect microcapillary integrity. Dark circles and eye puffiness is also reduced by decreasing skin fragility in the eye area via strengthening of the Cellular Matrix supporting microvasculature network. For enhanced eye puffiness results we recommend using Aldavine 5x in combination with the African plant, Chrysanthellum indicum (Lanachrys), which stimulates lipolysis. Ideal for the alleviation of dark circles, rosacea, spider veins, sensitive/ irritated skin, sun burn, razor burn and after laser treatment. Recommended use level: 1-5%. 5x : 0.2-1% CYTOFRUIT WATERS Bergamot (INCI: Citrus Aurantium Bergamia Fruit Extract) is an organic certified water from Bergamot fruits harvested in Mediterranean organic fields. Bergamot offers calming and antiseptic properties for irritated skin as well as cooling and refreshing benefits. Ideal for use in cleansers and toners to achieve clear and flawless skin. Thanks to the presence of oligo-elements, this CYTOFRUIT Water could sustain skin biological benefits through an improvement of cell vitality, a protection against external agents or a physiological improvement. Standard grade (Bio 99) is preserved with Potassium Sorbate. Bio grade is available and is preservative-free. Recommended usage level: 1 100% ENNACOMPLEX 261 (INCI: Aqua, Propylene Glycol, Aesculus Hippocastanum Seed Extract, Arnica Montana Flower Extract, Hamamelis Virginiana Leaf Extract, Hedera Helix Leaf Extract, Hypericum Perforatum Flower Extract, Vitis Vinifera Leaf Extract) is a botanical complex especially intended to make healing and normalising products for people suffering from a blotchy and often itchy complexion. With tonic, astringent and vasoconstrictive properties, it stimulates and regulates the micro-blood circulation, heals blotches and redness, and softens the skin. Recommended use level: 3-10% ENNACOMPLEX 262 (INCI: Aqua, Propylene Glycol, Anthemis Nobilis Flower Extract, Calendula Officinalis Flower Extract, Centaurea Cyanus Flower Extract, Chamomilla Recutita Flower Extract, Hypericum Perforatum Extract, Tilia Cordata Flower Extract) is a botanical complex intended to formulate products which target the causes and effects of sensitive and irritated skin (redness, tightness, dryness and blemishes). It contains a synergistic blend of Saint John s Wort flower, Cornflower, Linden (lime) flower, Marigold (calendula) flower, Roman chamomile flower and German Chamomile (matricaria) flower which work together to alleviate all these aspects of problematic skin. Recommended use level: 2-10% Homeo-Soothe (INCI: Ascophyllum Nodosum Extract (and) Sorbitol (and) Water). Lucas Meyer Cosmetics has developed 3 unique ingredients extracted from Algae in order to create Homeosta-Sea. Homeostasis comes from the Greek homoios (same, like, resembling) and stasis (to stand, posture). Homeo-Soothe is extracted from a Brown Seaweed well known to tolerate desiccation, important temperature variations and high saline water. Homeo-Soothe reduces the inflammatory response and protects the skin against deleterious consequences of environmental insults. Recommended use level: 0.5-2%

7 INKA KRAMERIA (INCI: Propanediol (and) Water (and) Krameria Triandra Root) is a natural, preservative-free and organic certifiable ingredient that provides astringent and anti-inflammatory properties. The plant of Krameria tiandra also offers photoprotective properties and is recommended for protection against UVB radiation. Recommended use level: 1-5% Lanatellis (INCI: Glycerin (and) Water (and) Chrysanthellum Indicum Extract (and) Camellia Sinensis Leaf Extract) is the combination of botanicals living in extreme conditions: Green Tea, King of Asia, together with Chrysanthellis, Queen of African Savannah. The combination of these two plant extracts offers a powerful free radical scavenging synergetic effect which protects and repairs UV damage and is an effective tool to fight rosacea. Recommended use level: 1-5% MDI Complex (INCI: Glycosaminoglycans) is a marine Glycosaminoglycan that inhibits the Matrix Metalloproteinase (MMP) enzymes that degrade and destroy the skin s Collagen network. MDI Complex can be used to neutralise excessive MMP activity, leading to a better Enzyme equilibrium needed for a natural healthy skin appearance. This equilibrium allows greater skin elasticity and increased resistance to external irritants. MDI Complex reduces the appearance of dark circles, spider veins and rosacea. Recommended use level: 1-5% MERISTEM (INCI: Aqua, Quercus Robur Root Extract) is a water extracted botanical ingredient sourced from Oak tree root growth tissue (Meristem). Plant Meristem cells are rich in substances physiologically active to support and protect cell growth, especially Phenylpropanoids which play a very important role in defending the plant against external stresses. In-vitro studies have shown that the material modulates the agonist of the TRPV3 pain receptor (nociceptive) system by more than 50% in 24h. In the skin this results in a lenitive and soothing behaviour. Recommended use level: 0.5-2% rich concentrate of nutritive compounds indispensable to development of new life. On a daily basis, the natural building blocks of Pangenine Lolium energise and protect the skin against external aggressors such as pollution, oxidative agents or chronic inflammatory factors (so-called inflame-ageing ). Pangenine Lolium exhibits a 4-in-1 action; skin nutrition thanks to essential Amino acids, energy for the Mitochondria, modulation of inflammatory mediators, and reduction of the accumulation of oxidative mediators at a tissue level. Recommended use level: 0.3-1% PHYTOSERENE (INCI: Phytosterols) an extremely pure beta-sitosterol, a natural micro-nutrient plant lipid which is found in the cells and membranes of the Pine tree. Chemically, the material is very similar to the animal lipid cholesterol. This plant sterol is however totally different in its biological function and because humans do not synthesise sterols in the body, it is necessary to replace daily losses. Phytoserine demonstrates the capacity to reduce skin redness after exposure to a chemical agent and diminish TEWL by forming a protective barrier on the skin. Recommended use level: % Plerasan Sun (INCI: Aqua, Maltodextrin, Lolium Perenne Flower Extract, Pleurotus Ostreatus Extract, Gluconolactone, Sodium Benzoate, Calcium Gluconate) A standardised active ingredient that provides a natural lentitive and soothing synergy for after sun applications. It is particularly efficient at modulating post-acute stress linked to sun exposure. Its effective film forming activity helps to prevent further dehydration by water loss. In addition, inflammatory mediators are modulated, skin and redness is reduced leaving the skin feeling reenergised. Skin moisturisation and microcirculation is also improved. Recommended use level: 1.0% PANGENINE LOLIUM (INCI: Maltodextrin, Pollen Extract) is derived from the solvent free extraction of Lolium Perenne, harvested from a controlled source of pesticide-free crops. It is a

8 RED CLAY (INCI: Illite) is an Illite-Kaolinite-type clay extracted in France and naturally dried under the sun. RED CLAY is a natural ingredient intended to prepare creams, pastes, masks, wrap and bath products for skin and hair care. With soothing and softening properties, RED CLAY is especially dedicated to irritated skin or combination skin with blemish problems. Recommended usage level: 1-25% SKINVEIL 500 (INCI: Sericin) is a Seresin protein extracted as a waste bi-product from the production of Silk. Unlike other proteins of this nature, the full molecular weight is maintained by extracting the material through a patented precise process, thus ensuring a minimum size of 500 kda. The exceptionally large size confers a bioactivity to the molecule that is lacking in smaller, degraded proteins from a similar source. Its high level of purity is obtained through a precisely controlled pharmaceutical grade lyophilisation process. SKINVEIL 500 helps to soothe skin irritation, visibly calms redness, restores Epidermis protection and reinforces the skin s own natural defences making it ideal for sensitive skin applications. Recommended use level: 0.5 3%

9 Keratolytic Agents A.H.A. EXTRACT 44 GLYCERIN (INCI: Aqua, Glycerin, Citric Acid, Lactic Acid, Glycolic Acid, Malic Acid, Tartaric Acid, Citrus Medica Limonum Extract, Pyrus Malus Extract, Saccharum Officinarum Extract, Vaccinium Myrtillus Extract, Vitis Vinifera Extract) is a mix of fresh fruits extracts (Lemon, Bilberry, Apple, Sugar cane and Grape) with a complementary blend of alpha-hydroxyacids (Citric, Lactic, Glycolic and Tartaric), also called fruit acids. It is a standardised extract with a 44% AHAs content in water and vegetal glycerin with no preservative. AHAs (alpha hydroxy acids) have been shown to improve the appearance of the skin by enhancing smoothness, luminosity and tone and also demonstrate exfoliating and moisturising activity. On penetrating the Stratum corneum, AHAs initially diminish corneocyte cohesion, readily detectable by desquamation. AHAs also reduce sebum secretion and deliver better moisturisation to the skin. Recommended usage level: 2-8% BAMBOO FIBRES POWDER (INCI: Bambusa Arundinacea Stem Extract) is a micronised and standardised powder of Bamboo (Bambusa vulgaris) fibres. It is a natural oriented and very soft scrub agent with practical function to create smooth and fresh skin. It is compatible with all cosmetic formulations. The BAMBOO FIBRES POWDER is suggested as a very soft scrub agent, especially for delicate and sensitive skin types. When incorporated in a cleansing or massaging product, the product has the property to softly stimulate the micro-blood circulation by its mechanical and physical action on the skin. Its controlled particle size around 60 µm ensures consistent performance. Recommended usage level: 5-10% CITRUS EXFOLIATING POWDER (INCI: Citrus Aurantium Dulcis Peel Powder, Citrus Grandis Peel Powder, Citrus Medica Limonum Peel Powder) is made from the solid part of citrus fruits (orange, lemon and grapefruit) produced to yield standardised nonaggressive scrub particles. It is a natural oriented body scrub agent with big particles which is compatible with all cosmetic formulations. CITRUS EXFOLIATING POWDER is suggested as a body scrub for every type of skin and can be used in liquids, gels, as a cake or in bar cleansing preparations. When incorporated into a body cleansing product, the product has the property to stimulate the microblood circulation by its mechanical and physical action on the skin. It also removes the old horny layer, wastes, dusts from the skin, and accelerates the skin metabolism. Its natural colour and pleasant odour make the CITRUS EXFOLIATING POWDER suitable for the highest quality products while its controlled particle size ensures consistent performance. Recommended usage level: 3 10% ENN ACTIVE PAPAYA (INCI: Maltodextrin, Carica Papaya Fruit Extract) is a watersoluble concentrated powder extract of Papaya (Carica papaya) fruits which contains a minimum of 5% Papain enzyme, a proteolytic enzyme with cleansing and keratolytic properties. ENN ACTIVE PAPAYA can be used as a natural cleansing agent. Recommended use level: 0.5-3% MultiSal Naturally Smooth (INCI: Maltodextrin, Salix Alba (Willow) Bark Powder, Colloidal Oatmeal, Sodium Bicarbonate, Hydrated Silica (amorphous), Glycyrrhiza Glabra (Licorice) Root Extract, Carica Papaya (Papaya) Fruit, Bromelain) Encapsulated salicylic acid (SA) is best known for the treatment of dermatitis, acne, psoriasis, calluses, and more. It works as a keratoic, comedolytic and bacteriostatic agent, causing the cells of the epidermis to shed more readily, opening clogged pores and neutralising the bacteria within. The active ingredients that help to treat these skin conditions are papyia, bromelien, and suprapein. The MultiSal technology provides extended release onto the skin, exposing the skin to small amounts of SA overtime. This unique feature allows higher levels of SA to remain on the skin for several hours, for better efficacy and acne-fighting power without irritation. An important benefit of the MultiSal technology is enhanced efficacy from a rinse-off application. The cationic charge of the shell s surface provides superior adhesion onto the skin. This benefit makes it a valuable technology for products that are rinsed off the skin shortly after application. Recommended use level: Cosmetic: Up to 1.67, OTC: , Rx: Over 6.67.

10 MultiSal Salicylic Acid (Hydrolyzed Corn Starch, Cocamidopropyl Dimethylamine, Glyceryl Stearate, Salicylic Acid, Hydrated Silica). MultiSal technology extends the release of Salicylic acid (SA) onto the skin. It exposes the skin to very small amounts of acid over a longer time, rather than one large amount all at once, as is the case with free SA. This unique feature allows higher levels of SA to remain on skin over several hours. The end result is longer-lasting efficacy and acne-fighting power without irritation. Suitable for anhydrous applications such as soap bars, on-the-go sticks, body powders, and cosmetics. As well as rinse-off whereby the MultiSal technology provides enhanced efficacy due to the cationic nature of the surface of the shell allowing superior adhesion to the skin. Recommended use level: Up to 5% (0.5% Salicylic acid) SalSphere Salicylic Acid (INCI: Cocamidopropyl Dimethylamine, Salicylic Acid, Water, Polysorbate 80, Phenoxyethanol, Ethylhexylglycerin, Carthamus Tinctorius (Safflower) Seed Oil, Olea Europaea (Olive) Fruit Oil). SalSphere Salicylic Acid slowly releases SA in its most potent form over time. Delivering the SA in this controlled fashion allows the skin to maintain a balanced ph after contact with the acid. The resulting skin ph does not drop into a range that could irritate sensitive skin. Suitable for anti-acne and anti-ageing applications such as, cleansers, lotions and creams. Recommended use level: Up to 1.67% (0.5% salicylic acid) SalSphere Clear Skin (Water, Cocamidopropyl Dimethylamine, Salicylic Acid, Lactic Acid, Phenoxyethanol, Sodium Hydroxide, Ethylhexylglycerin). SalSphere Clear Skin is a delivery system designed to rejuvenate and clear the skin of blemishes. Its ingredients work synergistically to gently exfoliate the skin and provide superior moisturisation. SalSphere Clear Skin is an ideal technology for various daily skin care applications such as face and body washes, lotions, toners, and gels. Recommended use level: Up to 10% SalSphere Even Skin (INCI: Salicylic Acid, PEG-8, Isostearamidopropyl Ethyldimonium Ethosulfate, Propylene Glycol, Carthamus Tinctorius (Safflower) Seed Oil, Olea Europaea (Olive) Fruit Oil) is designed to gently exfoliate the skin as well as providing a significant increase in exfoliation as compared to free (non-encapsulated) Salicylic Acid (SA) from a wash application. SA is a poorly-soluble ingredient and has always challenged formulation chemists with low solubility and ph levels. SS ES is a revolutionary solution that is easy to use in water and alcohol-free formulations. The encapsulated active is designed to be compatible with commonly used, cost effective carbomer-based thickeners to produce clear products such as, facial wash and lotion. This technology enables creation of new products in a single step, by adding the technology to the prepared base in an easy mixing process. SS ES is highly loaded with SA and can be diluted to any concentration desired. In dermatology and dermo-cosmetics, the technology is best for the treatment of dermatitis, acne, psoriasis, calluses, and more. In the cosmetic area, a lower concentration of SS ES is recommended for daily skin toning, brightening, scar and pore reduction, excess sebum. Recommended use level: Cosmetic: Up to 1.67; OTC: ; Rx: Over 6.67 SalSphere Severe Acne Relief (Cocamidopropyl Dimethylamine, Salicylic Acid, Water, Polysorbate 80, Glycerin, Butyrospernum Parkii (Shea Butter) Fruit, Ascorbic Acid, Benzalkonium Chloride, Camellia sinensis Leaf Extract, Isomerized Safflower Acid, Palmitoyl Tripeptide-5, Anthemis nobilis Flower Extract, Maltodextrin, Cera alba, Silica, Palmitic Acid, Clay, Zinc Sulfate, Fucus vesiculosis (Seaweed) Extract, Phenoxyethanol, Ethylhexlglycerin). SalSphere Severe Acne Relief provides multiple benefits to the skin including powerful, yet skin-friendly exfoliation, reduction of excess sebum, and antimicrobial, anti-inflammatory and skin reparative activity. The technology is designed to provide an alternative treatment prior to the use of expensive prescription medications and their accompanying side effects. Suitable for topical skin care and acne treatment including applications such as cleansers, lotions, creams, and gels. Recommended use level: Up to 1.67% (0.5% salicylic acid) SalSphere Skin Smoothing (Water, Cocamidopropyl Dimethylamine, Salicylic Acid, Phenoxyethanol, Ethylhexylglycerin). SalSphere Skin Smoothing brightens and smooths the skin to restore a youthful appearance. The technology provides gentle exfoliation (optimises the effectiveness of Salicylic acid in rinse-off as well as leave-on applications) to reduce the appearance of scars and blemishes. Reveals fresher, brighter skin with even tone. Opens pores to prevent future blemishes. SalSphere Skin Smoothing maintains a skin friendly ph making it suitable for daily use skin care and antiaging products such as cleansers, gels, lotions, and creams. Recommended use: up to 5%

11 Retinol-type It is a well known fact that severe acne sufferers are prescribed topical and oral treatments of Retinol. Whilst this treatment is very successful it comes with a number of undesirable side effects. This is where Retinol countertypes come into their own. We are pleased to offer the following safe alternatives to Retinol. Kahai Oil (INCI: Caryodendron orinocense nut oil) is a 100% natural oil, extracted by cold pressing the nuts of the Cacay tree. It has a high penetration capability, a dry skin feel, and a mild nutty scent, which fades quickly. Its high content of natural Vitamin E, F & Retinol nourishes, softens and repairs damaged skin. Kahai Oil revitalises the skins radiance, reduces fine lines and wrinkles, and giving it a long lasting hydration. Kahai Oil contains 50% more Vitamin E and twice the amount of Linoleic Acid than Argan oil; and it has three times more Retinol than Rose Hip Oil. Recommended use level: Various. Lanablue (INCI: Sorbitol (and) Water (and) Algae Extract) takes its force from the heart of the resources of the Cascadia region in North America and is blue in colour (no colour when formulated) due to the natural pigment of Phytosienine. Extract of Endemic Cyanophyceae harvested in wild conditions, Lanablue has a high content of group B Vitamins, Amino acids and specific pigments. It acts like natural Retinoids (without the side effects) on Keratinocytes differentiation thus smoothing and densifying the Epidermis. Lanablue, like Retinoids, influences different markers such as: Filaggrin: marker of cell differentiation, it contributes to maintain skin hydration and liberates natural moisturising factors; Loricrin: marker of Corneocyte differentiation; Calgranulin A, Calgranulin B and Psoriasin: markers of basal proliferation, involved in skin repair process; TIMP 1 (tissue inhibitor of Metalloproteinase-1): natural inhibitor of Matrix Metalloproteinase (MMP) which regulates the integrity of the Extracellular structure. Recommended use level: 1-5% increasing the bioavailability of Vitamin A inside of the intracellular medium. This technology gives a thermodynamically stable system made of droplets of less than 100 nm and offers the possibility to incorporate Vitamin A directly in aqueous or hydroalcoholic liquid products, or in emulsions with continuous water phase. Recommended use level: 1-3% MultiSal Retinol (Silica, PPG-3 Benzyl Ether Myristate, Retinol, Polysorbate 20, Polyethylenimine, BHT, BHA, Lauryl Laurate, Zea Mays (Corn) Starch, Hydrolyzed Corn Starch, Hydrolyzed Corn tarch Octenylsuccinate). Retinol has been utilised extensively as an anti-wrinkle therapy. The molecule acts by inducing glycosaminoglycan and collagen synthesis, rejuvenating the firmness and youthful appearance of skin. A challenge regarding the use of Retinol is its susceptibility to oxidation, which ultimately reduces the potency and limits effectiveness. Due to its ability to enhance skin turnover, Retinol can cause irritation on consumers with sensitive skin. MultiSal technology is based on doublelayered encapsulation of retinol. The microsphere ruptures when the lotion is rubbed into the skin, releasing the sub-micron spheres inside. The core is comprised of botanical lipophilic ingredients that partition into the skin, thus modulating the slow release of the encapsulated retinol over time. MultiSal Retinol reduces the appearance of fine lines in as little as 2 weeks. MultiSal Retinol is recommended for use in anti-aging and skin rejuvenation products including lotions, creams, lip care and cosmetics as well as anti-acne. Recommended use level: 1-2% MICROEMULSION A (INCI: Aqua, PEG-40 Hydrogenated Castor Oil, Glycerin, Retinyl Palmitate, Citric Acid) is a unique water-dispersible delivery system

12 Treatment Avenna MP25 (INCI: Avena Sativa Meal Extract) harnesses the powerful benefits of an Oat (Avena sativa) extract containing 21-25% Beta-glucan, a material that has structural similarities with Hyaluronic acid. This material is widely used for building high viscosity and as a moisturiser for imparting smoothness to the skin. These polysaccharides have been found to be moisturising and wound-healing ingredients, can also stimulate Collagen and Elastin production and be a powerful stimulator of the immune system. Avenna MP25 is a source of many other cosmetically beneficial components such as proteins, 17 free amino-acids, essential fatty acids, minerals and six vitamins - the material is hence a powerful anti-oxidant and skin normalising ingredient. Recommended use level: % INKA MATICO (INCI: Propanediol (and) Water (and) Piper Angustifolium Leaf) is a unique, natural, preservative-free, organic certifiable ingredient, obtained from selected leaves of Piper aduncum (matico), native plant to Peru. Matico has a millenary tradition of use in cleansing the skin of impurities, as skin protector, wound healer, antiseptic, astringent and to treat skin problems. Recommended use level: 1 5% Miniporyl TM (INCI: Isopentyldiol, Trifolium Pratense (Clover) Flower Extract) extracted from Red Clover Extract and titrated in Biochanin A to purify and rebalance skin. The enlargement of pores is caused by Corneocytes retaining their nucleus. This leads to abnormal desquamation and accumulation of cell debris, which cause pores to clog. As a result skin loses tonicity and firmness. These effects are further worsened by sun, tobacco, food, bad cleansing etc. Miniporyl TM improves Keratinocyte differentiation to obtain nucleusfree Corneocytes as well as inhibiting 5α-reductase activity to decrease sebum production. Overall the size and appearance of pores is reduced for flawless skin! Recommended usage: Preventative face care: %; Intensive face care: % limited and often results in dryness and discomfort. When skin is exposed to a large dose of benzoyl peroxide all at once, it can become extremely irritated, resulting in reduced user compliance. Users with sensitive skin may even suffer from burning, itching, peeling and swelling of the skin. SalSphere BPO is a sub-micron encapsulation system of benzoyl peroxide that releases slowly over time for a more potent and effective acne treatment. Suitable for anti-acne products such as creams, lotions, spot treatments, facial cleansers and sensitive skin. Recommended use level: 10-40% SalSphere Even Skin (INCI: Salicylic Acid, PEG-8, Isostearamidopropyl Ethyldimonium Ethosulfate, Propylene Glycol, Carthamus Tinctorius (Safflower) Seed Oil, Olea Europaea (Olive) Fruit Oil) is designed to gently exfoliate the skin as well as providing a significant increase in exfoliation as compared to free (non-encapsulated) Salicylic Acid (SA) from a wash application. SA is a poorly-soluble ingredient and has always challenged formulation chemists with low solubility and ph levels. SS ES is a revolutionary solution that is easy to use in water and alcohol-free formulations. The encapsulated active is designed to be compatible with commonly used, cost effective carbomer-based thickeners to produce clear products such as, facial wash and lotion. This technology enables creation of new products in a single step, by adding the technology to the prepared base in an easy mixing process. SS ES is highly loaded with SA and can be diluted to any concentration desired. In dermatology and dermo-cosmetics, the technology is best for the treatment of dermatitis, acne, psoriasis, calluses, and more. In the cosmetic area, a lower concentration of SS ES is recommended for daily skin toning, brightening, scar and pore reduction, excess sebum. Recommended use level: Cosmetic: Up to 1.67; OTC: ; Rx: Over 6.67 SalSphere BPO (Water, Benzoyl Peroxide, Hydroxyethyl Behenamidopropyl Dimonium Chloride, Butyrospermum Parkii (Shea Butter) Fruit, Euphorbia Cerifera (Candelilla) Wax). It is known that BPO is difficult to formulate with due to its poor water solubility and high instability. Additionally, while it is a proven antibacterial agent, clinical success of BPO in acne-fighting products is

13 SalSphere SalOxy (INCI: Decafluoropentane, Water, Polyhydroxystearic Acid, Isononyl Isononanoate, Cocamidopropyl PG-Dimonium Chloride Phosphate, Butyrospermum Parkii (Shea Butter), Glyceryl Stearate, Stearic Acid, Cetearyl Alcohol, Sodium Lauroyl Glutamate, Cocamidopropyl Betaine Dimethylamine). SalSphere SalOxy is an advanced system for delivering oxygen to the surface of the skin. This technology is designed to deliver oxygen, with bubbles serving as a purifying mechanism. SalSphere SalOxy achieves this by controlling the release of an oxygen-releasing species. The release of the gas as the consumer product is applied creates a luxurious experience. This foam can be used as a sensory cue that treatment has begun, or can simply add a positive, lively note to a formulation as a foaming experience. Advantages include a unique foaming experience (SalSphere technology provides a high volume foam without sulfate-based surfactants or propellants), skin and environmentally friendly (no harsh chemical needed that would erode the skin or persist in the environment) as well as being cost effective (effective at low levels and requires no special packaging). Recommended inclusion level: 1.5 5% improve moisturisation. Recommended use level: % YELLOW CLAY (INCI: Mica) is a natural Illite-Kaolinite-type clay extracted in France and naturally dried under the sun. YELLOW CLAY is a natural ingredient intended to prepare creams, pastes, masks, wrap and bath products for skin and hair care. It is especially dedicated to normal and combination skin types with imperfections and dull complexion. A facial mask with YELLOW CLAY smoothes lines, deeply cleanses and gently tones the skin. Recommended usage level: 1-25% SalSphere Severe Acne Relief (Cocamidopropyl Dimethylamine, Salicylic Acid, Water, Polysorbate 80, Glycerin, Butyrospernum Parkii (Shea Butter) Fruit, Ascorbic Acid, Benzalkonium Chloride, Camellia sinensis Leaf Extract, Isomerized Safflower Acid, Palmitoyl Tripeptide-5, Anthemis nobilis Flower Extract, Maltodextrin, Cera alba, Silica, Palmitic Acid, Clay, Zinc Sulfate, Fucus vesiculosis (Seaweed) Extract, Phenoxyethanol, Ethylhexlglycerin). SalSphere Severe Acne Relief provides multiple benefits to the skin including powerful, yet skin-friendly exfoliation, reduction of excess sebum, and antimicrobial, anti-inflammatory and skin reparative activity. The technology is designed to provide an alternative treatment prior to the use of expensive prescription medications and their accompanying side effects. Suitable for topical skin care and acne treatment including applications such as cleansers, lotions, creams, and gels. Recommended use level: Up to 1.67% (0.5% salicylic acid) Technohyal TETR-HA LF (INCI: Aqua, Pentylene Glycol, Sodium Hyaluronate Crosspolymer) an affordable and cost-effective cross polymer Hyaluronic acid for light hydration. TETR-HA LF is able to bind 2-3 times more water (compared to standard Hyaluronic acid at the same percentage) effectively reducing water evaporation from the skin to

14 Interested? Then please call one of our team for more information... Andrew Goodwin Managing Director T: M: E: Clare Goodwin Technical Sales Director T: M: E: W: infinity-ingredients.co.uk

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