The legacy behind Q-switched technology. MedLite C

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1 The legacy behind Q-switched technology MedLite C 6

2 A Booming Market Laser treatment of tattoos and pigmented lesions will expand with aging populations in the U.S., Europe and Asia. Worldwide procedure volume is expected to reach 7.5 million in 2017, generating $1.3 billion in fees 1.

3 MedLite C6 Q-Switched Nd:YAG laser features proven PhotoAcoustic technology and multiple wavelengths for efficient, reproducible treatment on all patient skin types. Tattoo Removal Full Color Spectrum Epidermal and Dermal Pigmented Lesions -- Nevus of Ota -- Sun Damage Skin Resurfacing Wrinkle Reduction Acne Scar Reduction

4 PhotoAcoustic Technology The hallmark of PhotoAcoustic technology is high peak power and short pulse duration. This combination generates a PhotoAcoustic action against the target chromophore whether it s tattoo ink, pigment or collagen. The electro-optic (EO) Q-Switch, acting as a high-speed shutter, stores energy between pulses enabling the laser to produce peak power output of 200 megawatts in 5-20 nanosecond pulse widths. The MedLite C6 forces energy at such a high rate, the target chromophores vibrate and shatter, without harming the surrounding skin. Flat-Top Beam Profile PhotoAcoustic technology is delivered through MedLite C6 s homogenous, flat-top beam profile, without spikes or hot spots. As a result, energy is distributed evenly from the perimeter to the center of the beam, resulting in better fragmentation of the target chromophores with minimal to no epidermal injury. 1200mj

5 Proven Reliablility Built on ConBio s original Q-switched technology, MedLite C6 is best known as the industry s gold standard laser for multi-colored tattoo removal. It also provides a wide range of effective treatment applications, regardless of patient skin type. Anti-Aging Maintenance MedLite C6 s Q-Switched Nd: YAG technology can help resurface the skin through collagen stimulation. 2 Epidermal and Dermal Pigmented Lesions MedLite C6 is ideal for treating a wide variety of pigmented lesions including age spots, solar lentigines, café-au-lait lesions and dermal melanocytosis, including Nevus of Ota and Hori s Nevus. Non-Ablative Skin Resurfacing (Wrinkle/Acne Scar Reduction) The Q-Switched 1064nm wavelength reduces acne scars and wrinkles with minimal to no downtime or discomfort.

6 Four wavelengths Multiple Applications Depth of Penetration in the Skin Wavelength (nm) Epiderma Derma Hypoderma Advanced Tattoo Removal 1064nm targets dark ink 532nm targets red 585nm targets sky blue 650nm targets green Absorption Spectrum for Melanin and Hemoglobin Oxyhemoglobin Absorption Melanin Absorption 532nm YAG 1064nm YAG Optional Features Handpieces extend the wavelength capabilities of the laser to include 585nm (yellow) and 650nm (red) for the treatment of tattoos and pigmented lesions.

7 Before After 6 Tx Before After 5 Tx Courtesy of Niwat Polnikorn, MD Before After Multiple Tx Courtesy of Bruce Saal, MD Courtesy of Larry Weinstein, MD After 2 Tx Courtesy of Lauren Chavez, MD Before

8 Tattoo Removal & Pigmented Lesion Workstation System Type Nd:YAG Dye Impregnated Polymers Wavelength 1064 nm 532 nm 585 nm* 650 nm* Pulse Width 5-20 nsec <7 nsec Maximum Fluence per Spot Size (J/cm2) 8mm 2 J/cm 2 6mm 3.5 J/cm J/cm 2 4mm 8 J/cm J/cm 2 3mm 12 J/cm 2 5 J/cm 2 2mm 5 J/cm J/cm J/cm 2 Maximum Rep Rate 10Hz 2 Hz 1 Hz Electrical Requirements 220 V, single phase, 8 Amp or 110 V, Single Phase, 15 Amps Aiming Beam Red Size (H x W x D) 44.5" x 12" x 28.5" (113 cm x 30.5 cm x 72.5 cm) Weight 128 lbs (58 kg) *Optional Handpieces SOURCES 1 Medical Insight, Inc. January Liu, H., MD, PhD, Dang, Y., PhD et al. (2008). Laser induced collagen remodeling: A comparative study in vivo on mouse model. Lasers in Surgery and Medicine 40:B-19 CORPORATE HEADQUARTERS United States Cynosure, Inc. 5 Carlisle Road Westford, MA Toll-Free: VISIBLE AND INVISIBLE LASER RADIATION AVOID EYE OR SKIN EXPOSURE TO DIRECT OR SCATTERED RADIATION. EN : 2007 CLASS 4 LASER PRODUCT ENERGY: 1 J MAX PULSELENGTH: < 20ns WAVELENGTHS: 1064nm, 532nm, 650nm 585nm AIMING BEAM: 650NM < 1MW CW MedLite C6 and Cynosure are registered trademarks of Cynosure, Inc Cynosure, Inc Rev 4 2/13