224 Journal Of Inner Mongolia Medical University June 2018 Vol.40 No.3 LASIK SBK * 010050 laser in situ ker - atomileusis LASIK Sub-Bownom-keratomileusis SBK 2015-09~ 2016-09 120 LASIK 60 SBK 60 1wk 1mo 3mo 6mo fluorescence staining FL tear break-up time BUT SchirmerⅠtest SⅠt 1wk 1mo LASIK SBK FL fluorescence staining FL LASIK 3mo 6mo BUT 1wk 1mo 3mo LASIK SBK 6mo P>0.05 SⅠt 1wk 1mo 3mo P<0.05 SBK 6mo P > 0.05 SBK LASIK SBK LASIK R779.63 A DOI:10.16343/j.cnki.issn.2095-512x.2018.03.005 2095-512X 2018 03-0224-05 THE COMPARATIVE ANALYSIS OF DRY EYE SYNDROME OF LASIK AND SBK OF MONGOLIAN PATIENTS IN INNER MONGOLIA XING Jian-nan ZHAO Hai-xia SUI Yao The Affiliated Hospital Inner Mongolia Medical University Hohhot 010050 China Abstract Objective To compare the changes of dry eye after laserinsitukeratomileusis LASIK and Sub-Bowman-Keratomileusis SBK for Mongolian patients in Inner Mongolia.Methods Retrospective analysis from September 2015 to September 2016 there were 120 Mongolian patients in three generations are all Mongolians come to our ophthalmology department to have myopia operation.there are 60 patients in group LASIK and 60 patients in group SBK. And observe the changes before operation and the changes that happened in fluorescence staining FL tear break-up time BUT and SchirmerⅠ test SIT after the operation for one week one month three months and six months.results After the operation for one week and one month we can see the dot dyeing of corneal epithelium of the FL of both group LASIK and group SBK and the number of corneal staining in group LASIK was more.the statisti- 2018-01-09 2018-05-06 1989-2015 E-mail nmghhzhx@ 163.com 010050
2018 6 40 3 225 cal results were of statistically significance and the proportion of the number of corneal staining eyes of two groups in the three months and six months after operation was not statistically significant.in the two groups the difference was statistically significant between the two groups in the one week one month and three months after the BUT operation.and LASIK group has a shorter breakup time of tear film and the SBK group enjoys a shorter recovery time.however there was no significant difference between the two groups in the six months after operation.the SIT experiment results of the patients in two groups shows that the comparative difference of the two groups in the one week and three months after operation was of statistically significant.and the SBK group has a shorter recovery time of tear secretion function while the data in the six months after operation was not statistically significant. Conclusion The Mongolian patients in Inner Mongolian are all tend to cause dry eye syndrome with different levels after the SBK operation and LASIK operation.and compare to those patients who accepted LASIK operation those patients who accepted SBK operation enjoys a shorter recovery time. Key words laserinsitukeratomileusis sub-bowman-keratomileusis dry eye 60 120 2 LASIK SBK LASIK 28 56 32 64 19 1 20 ~ 32 25 ± 1.3 SBK 22 44 80 Trokel 2 38 76 20 ~ 34 26±0.8 1.2 0.9% 3 4 LASIK LASIK SBK LASIK Moria M2 SBK 12 90 ~ 110μm LASIK SBK 100mm 130 ~ 160μm 9.0 ~ 10.5mm 5 BSS 6 LASIK SBK 1d 1 1.1 2015-09 ~ 2016-09 1.3 LASIK SBK 2013
226 Journal Of Inner Mongolia Medical University June 2018 Vol.40 No.3 7 1 5min +Schirmer I 5mm /5min 2 +BUT 5s 3 +5mm /5min <SchirmerI 10mm /5min+ 4 +5S<BUT 10S+ 2 1.4 1.4.1 cornealfluorescence staining FL 1wk 1mo LASIK SBK 2.1 0.9% LASIK P<0.05 6mo 3mo P>0.05 0 ~ 3 0 1 1 ~ 30 1 >30 2 BUT 1wk 1mo 3mo 3 7 P<0.05 LASIK 1.4.2 tear break-up time BUT 1.5 SPSS 16.0 x±s 珋 t P<0.05 2.2 BUT s SBK 3 6mo P>0.05 2 3 3 2.3 SⅠt Schirmer Ⅰ 1wk 1mo 3mo 1.4.3 SchirmerⅠtest SⅠt P<0.05 3 SBK 6mo P > 1 /3 0.05 3 Tab.1 1 LASIK SBK x±s 珋 Comparison of corneal FL scores between LASIK group and SBK group 珋 x±s 1wk 1mo 3mo 6mo LASIK 0.37±0.312 1.8±0.840 1.45±2.103 0.53±0.566 0.37±0.551 SBK 0.38±0.381 1.48±0.504 0.80±1.338 0.38±0.854 0.33±0.475 t 0.262 2.505 2.020 0.378 0.355 P 0.794 0.014 0.046 0.706 0.723 Tab.2 2 LASIK SBK BUT s x±s 珋 Comparison of corneal BUT s between LASIK group and SBK group 珋 x±s 1wk 1mo 3mo 6mo LASIK 14.92±0.279 7.38±0.49 8.87±1.049 10.40±1.123 14.47±0.676 SBK 14.87±0.503 7.97±1.93 10.33±0.729 13.03±1.626 14.65±0.606 t 0.673 2.259 8.894 10.324 1.565 P 0.502 0.026 0.00 0.00 0.12
2018 6 40 3 227 Tab.3 3 LASIK SBK SⅠt mm x±s 珋 Comparison of corneal SⅠt mm between LASIK group and SBK group 珋 x±s 1wk 1mo 3mo 6mo LASIK 15.08±0.279 7.42±0.497 8.78±0.739 10.35±1.363 15.13±0.503 SBK 15.13±0.566 8.17±0.693 11.30±2.553 13.15±3.074 15.17±0.376 3 t 0.613 6.812 7.335 4.146 0.411 P 0.541 0.00 0.00 0.00 0.682 1wk SBK LASIK SBK LASIK SBK LASIK 8~ 10 1. J. 11 2011 20 3 148-150 3 ~ 9 2 Solomon KD Fernandez de castro LE Sandoval HP et al. 9 ~3 satisfaction J.Ophthalmology 2009 116 691-701 3 Dawson DG Grossniklaus HE Mccarey BE et al. Biomechanical and wound healing characteristics of corneas after 12 LASIK excimer laser keratorefractive surgery is there a difference 12 between advanced surface ablation and sub-bowman's keratomil-eusis J.Refract Surg 2008 24 1 90-96 12 SBK 4 Ambrosio rjr Tervo T Wilson SE. LASIK - associated dry eye and neurotrophic epitheliopathy pathophysiology and 13 14 2008 24 4 396-407 SBK 3mo 5. LASIK 6mo J. 2016 16 3 472-475 6.LASIK J. 2010 1 5 22-23 7. 2013 J. 2013 49 1 73-75 8. 15 SBK J. 2015 27 9 1117-1118 100mm LASIK 16 17 9 Beheshtnejad AH Hashemian H Kermanshahani AM et 130mm LASIK al. Evaluation of tear osmolarity changes after photorefractive keratectomy J. Cornea 2015 34 12 1541-1544 18 19 10. J SBK 2017 33 1 108-110 LASIK SBK 20 21 LASIK world literature review quality of life and patient strategies for prevention and treatment J. Refract Surg 233
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