SAFETY DATA SHEET Phosphate Buffer, ph 6.5

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SAFETY DATA SHEET Phosphate Buffer, ph 6.5 Section 1 - Chemical Product and Company Identification SDS Name: Phosphate Buffer, ph 6.5 Catalog Numbers: B-149-2, B-150-2, B-151-2, B-153-2, B-158-3, B-161-3, SO-917 Company Identification: ROWLEY BIOCHEMICAL 10 ELECTRONICS AVENUE DANVERS, MA 01923 For information, call: 978-739-4883 Emergency Number: 800-424-9300 For CHEMTREC assistance, call: 800-424-9300 Section 2 - Hazards Identification GHS Classifications HEALTH HAZARDS H303 Acute Oral Toxicity: 5 H316 Skin Corrosion/Irritation: 3 H320 Eye damage/irritation: 2B Pictograms: Warning: May be harmful if swallowed. Causes mild skin irrritation. Causes eye irritation.

Precautionary Statement P260 Do not breathe fume/gas/mist/vapors. P264 Wash thoroughly after handling. P270 Do not eat, drink, or smoke when using this product. P305 + P351 + P338 If in eyes, rinse cautiously with water for several minutes. P309+P311 IF exposed or if you feel unwell: Call a POISON CENTER o doctor/physician. P312 Call a physician if you feel unwell. P332 + P313 If skin irritation occurs, get medical advice/attention. P337 + P313 If eye irritation persists, get medical advice/attention. P501 Dispose of contents/container in accordance with local/regional/national/international regulations. Section 3 - Composition, Information on Ingredients CAS# Chemical Name Percent 7758-80-7 Sodium Phosphate, monobasic 0.10w/v 7558-79-4 Sodium Phosphate, dibasic 0.04w/v 89-83-8 Thymol <0.05w/v 7732-18-5 Water 100v/v Section 4 - First Aid Measures Eye Exposure: In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician. Dermal Exposure: In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Contact a physician if condition worsens. Oral Exposure: If Swallowing seek immediate medical advice. Inhalation Exposure: If inhaled, remove to fresh air. If breathing becomes difficult, call a physician. Section 5 - Fire Fighting Measures Firefighters should wear proper protective clothing and self contained breathing apparatus with full piece operated in positive pressure mode to prevent contact with skin and eyes. Extinguishing Media: Use water spray, dry chemical powder, or appropriate foam. Flash Point: N/A NFPA Rating: (estimated) Health: 1; Flammability: 0; Instability: 0 Section 6 - Accidental Release Measures Procedure(s) of Personal Precaution(s): Wear protective gear.

Methods for Cleaning up: Absorb with sand, earth or vermiculite. Carefully sweep up and containerize for proper disposal. Section 7 - Handling and Storage Use care when handling. Wash thoroughly after handling. Store capped in a cool, well ventilated area. Keep away from incompatible materials. Section 8 - Exposure Controls, Personal Protection Engineering Controls: Use explosion-proof ventilation equipment. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Section 9 - Physical and Chemical Properties Physical State: Liquid Appearance: Clear ph: 6.5 +/- 0.10 Vapor Pressure: N/A Vapor Density: N/A Evaporation Rate: N/A Viscosity: N/A Boiling Point: N/A Section 10 - Stability and Reactivity Chemical Stability: Stable under ordinary conditions of use and storage. Heat and sunlight can contribute to instability. Conditions to Avoid: Heat, freezing. Incompatibilities with Other Materials: Reactive with oxidizing agents, acids. Hazardous Decomposition Products: Products of degradation are less toxic than the product itself. Hazardous Polymerization: Will not occur. Section 11 - Toxicological Information

RTECS#: WA1900000 CAS# 7558-80-7: Acute oral rat LD50: 8290 mg/kg. CAS# 7558-80-7: Not listed by ACGIH, NTP, or CA Prop 65. Mutagenicity: Not Available RTECS#: CAS# 7558-79-4: Acute oral rat LD50: 17000 mg/kg. CAS# 7558-79-4: Not listed by ACGIH, NTP, or CA Prop 65. Mutagenicity: Not Available RTECS#: CAS# 89-83-8: Acute oral rat LD50: 980 mg/kg. Acute oral mouse LD50: 640 mg/kg. Acute oral guinea pig LD50: 880 mg/kg. CAS# 89-83-8: Not listed by ACGIH, NTP, or CA Prop 65. Mutagenicity: Causes damage to the following organs: kidneys, liver, central nervous system. Section 12 - Ecological Information Ecotoxicity: No information available. Environmental: No information available. Physical: No information available. Other: No information available.

Section 13 - Disposal Considerations Appropriate method of disposal of substance or preparation: Handled as hazardous waste and sent to an RCRA approved incinerator or disposed in an RCRA approved wasted facility. Section 14 Transport Information DOT Non-Regulated Section 15 - Regulatory Information Canada Regulatory Information WHMIS Classification: This product has been classified in accordance with the hazard criteria of the CPR, and the MSDS contains all the information required by the CPR. European/International Regulations European Labeling in Accordance with EC Directives Risk Phrases: R48/21/22 Harmful: danger of serious damage to health by prolonged exposure through inhalation and if swallowed. R36/37/38 Irritating to eyes, skin and respiratory tract. R42/43 May cause sensitization by inhalation and skin contact. Safety Phrases: S20/21 When using do not eat, drink or smoke S2 Keep out of the reach of children. S3 Keep in a cool place. S7 Keep container tightly closed. S9 Keep container in a well-ventilated place Section 16 - Additional Information MSDS Creation Date: 10/15/12 Revision #1. 4/14/2014 YM Co-sign CF The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Rowley Biochemical, Inc. be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Rowley Biochemical, Inc.has been advised of the possibility of such damages.