CONTENTS INTRODUCTION TO NEOGEN... PRODUCT RANGE INTRODUCTION... PRODUCT APPLICATIONS... PRE-MILKING... 5 PRE/POST-MILKING... 6

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DAIRY HYGIENE

INTRODUCTION TO NEOGEN... PRODUCT RANGE INTRODUCTION... PRODUCT APPLICATIONS... 2 3 4 CONTENTS PRE-MILKING... 5 PRE/POST-MILKING... 6 POST-MILKING BARRIERS... 8 POST-MILKING... 9 TEAT DIP CONCENTRATES... 10 CLUSTER FLUSH... 11 HOOF CARE... 12 ULTRA RANGE: CIRCULATION AND TANK CLEANERS... 13-14 PRODUCT POSITIONING... 15 POWDER CIP PRODUCTS... 16 OTHER PRODUCTS... 17 OTHER NEOGEN ANIMAL SAFETY PRODUCTS... 18 13

Neogen BioSecurity: world class biosecurity and animal safety. Neogen Corporation develops and markets products dedicated to food and animal safety. Neogen s Animal Safety Division is a leader in the development of animal genomics, along with the manufacturing and distribution of a variety of animal healthcare products, including diagnostics, pharmaceuticals, veterinary instruments, wound care, hygiene products and aquaculture. Your professional partner in dairy hygiene. The Neogen BioSecurity dairy hygiene range is benefiting from new product investment, underpinned by a commitment to high quality, in order to become a leader in animal safety. Neogen BioSecurity dairy hygiene products are developed and manufactured at Neogen s facility in Rochdale, United Kingdom. Not all products are available in all countries, please contact Neogen BioSecurity biosecurity.sales@neogeneurope.com or Tel: +44(0)1706 344 797 2

NEOGEN BIOSECURITY CLEANER AND DISINFECTANT PRODUCT LINES: Dairy Hygiene: Pre-milking and post-milking teat disinfectant to protect against on-farm udder infections in dairy ruminants. Circulatory cleaners and disinfectants for the highest level of hygiene in milking parlours and bulk tanks, both conventional and robotic. INTRODUCTION Poultry and Livestock: Broad spectrum disinfectants for infectious disease control in animal housing. High foaming detergents, pre-cleaners and sanitisers for animal housing and hatcheries. Food Processing: Food-safe cleaners and sanitisers for processing equipment, tanks and pipelines to prevent microbial food contamination and help meet stringent food safety standards. Degreasers and descalants to remove stubborn deposits. Aquaculture: Cleaners and disinfectants for disease control during grow-out production, egg disinfection and equipment sanitation to stop spread of disease and invasive species contamination. 3

HOOFCARE PRE-MILKING CLUSTER FLUSH DAIRY HYGIENE RANGE HARD SURFACE DISINFECTION POST-MILKING CIRCULATION CLEANING PRODUCT APPLICATIONS 4

Teat friendly products for preparation of the teats prior to milking. Pre-milking teat cleaning aims to limit transmission of mastitis causing bacteria through the milking system and safeguard the raw milk supply. Pre-milking teat preparation should provide rapid kill of bacteria on teat skin and assist milk let down, speeding up the milking process. PRE-MILKING Pre-Guard Ready-to-use pre-milking teat dip or spray Based on iodine and lactic acid Formulated with 3% emollient content for good teat conditioning Provides rapid action against bacteria Synofoam Pre-milking foam teat dip Ready-to-use formulation suitable for dip, spray and foam applications Based on lactic acid with added peppermint Superior foam for increased contact time and visibility on teats Formulated for gentle cleaning Synopure 1:7 Pre-milking teat dip concentrate Suitable for dip, spray or foam applications Based on lactic acid with added peppermint Dilute 1 part product to 7 parts water Superior foam for increased contact time and visibility on teats 5

Versatile dual purpose teat sanitisers for convenient pre/post-milking for dip or spray use. Pre/post-milking teat formulations are designed to provide teat protection and conditioning between milking periods and are ph buffered for stability. Synodex Teat dip or spray based on lactic acid Contains high levels of lactic acid and lactate High emollient content including lanolin for optimal skin condition Pleasant citrus odour with added limonene Suitable for use in organic milk production Synodine Teat dip or spray based on lactic acid and iodine Dual action based on lactic acid and iodine High emollient content for optimal skin condition Teatguard Ready-to-use pre/post-milking teat dip or spray based on a blend of iodine and lactic acid Contains a specially balanced emollient blend including glycerine Extremely effective broad spectrum disinfectant Laxsan Teat dip or spray based on lactic acid Contains 5.6% lactic acid and lactate High emollient content including lanolin for optimal skin condition Perfume free PRE/POST-MILKING Hexsan Pre/post-milking teat dip or spray based on lactic acid Specialised emollient blend including lanolin for optimal skin condition Effective broad spectrum disinfectant 6 All products are proven to pass EN 1656 tests.

7 - UK FARM DISTRIBUTOR

Post-milking teat disinfection for prolonged broad spectrum biocidal protection of teat skin between milking periods to improve milk quality and increase milk volume. Neogen BioSecurity post-milking teat products contain a specialised emollient complex to safeguard skin condition. Barrier teat dips form a protective film over the teat for prolonged protection. The barrier helps to prevent bacteria colonising on the teat or invading the teat orifice between milking periods. Synofilm Film forming barrier teat dip based on lactic acid Contains high levels of lactic acid and lactate for prolonged biocidal protection between milking periods Pleasant citrus odour Contains a multiple emollient blend including lanolin Beneficial in the recovery and prevention of cracked and chapped teats Suitable for organic milk production Synobarrier Film forming barrier teat dip based on iodine and lactic acid Dual action based on iodine and lactic acid Multiple emollient blend including lanolin for optimal skin condition Provides prolonged biocidal protection between milking periods to further prevent infection Iodoguard 5000* Ready-to-use thick barrier teat dip Based on 0.5% iodine Enriched with softening emollients and moisturiser Bactericidal, yeasticidal and virucidal protection Excellent coating properties POST-MILKING BARRIERS 8 *Coming soon, contact Neogen BioSecurity for further details.

Synoshield Ready-to-use teat dip or spray based on lactic acid Contains high levels of lactic acid and lactate with added peppermint Multiple emollient blend for optimal skin condition Suitable for use in organic milk production POST-MILKING Teatguard Plus Ready-to-use teat dip or spray based on a blend of iodine and lactic acid Contains a specially balanced emollient blend inlcuding glycerine Extremely effective broad spectrum disinfectant Does not require dilution in preparation for dipping the teat Iodospray 5500* Ready-to-use teat dip or spray Based on 0.55% stabilised iodine Proven effectiveness against pathogenic viruses, bacteria and yeasts Formulated with a moisturising teat conditioning system Contains emollient including lanolin DID YOU KNOW? TEAT DIPS CAN REDUCE THE INCIDENCE OF MASTITIS BY UP TO 95% 9 Studies show that pre-dipping in combination with post-dipping, is more effective in preventing mastitis than post-dipping alone. (Louisiana State University Agricultural Center) *Coming soon, contact Neogen BioSecurity for further details.

Synodine 1:3 Pre/post-milking teat dip or spray based on lactic acid and iodine Iodoguard Concentrate 1:4* Iodine based concentrate teat dip with high emollient content Synopure 1:7 Pre-milking teat foam concentrate based on lactic acid, with added peppermint Teatguard 1:3 Pre/post-milking teat dip or spray concentrate based on iodine and lactic acid TEAT DIP CONCENTRATES 10 *Coming soon, contact Neogen BioSecurity for further details.

The use of an effective cluster flushing routine can reduce the risk of mastitis through cross-contamination helping to maintain udder health and reducing the need for veterinary intervention. The Neogen BioSecurity cluster flush disinfectants can be applied via automatic systems, using hand held sprayers, or manual disinfection methods. CLUSTER FLUSH Peraguard Powerful non-rinse food industry disinfectant based on 5% peracetic acid Highly effective bactericide Chlorine free Leaves no residue Peraguard Plus A DEFRA approved biocidal industrial cleaner and disinfectant for circulation cleaning and industrial sanitisation Contains hydrogen peroxide solution, acetic acid and 5% peracetic acid Includes added surfactant for improved cleaning action and increased antimicrobial activity DID YOU KNOW? If infected milk residues from cluster units are not disinfected, they can cross-contaminate the following six to eight cows to be milked with the cluster. (AHDB Dairy) 11

A POWERFUL BLEND OF BIOCIDES AND HOOF HARDENERS FOR SAFE CLEANING AND DISINFECTION OF HOOVES Highly concentrated disinfectant with cleaning action Delivers broad spectrum disinfection Based on a blend of powerful biocides and hoof hardeners High detergency for safe cleaning and penetration of dirty hooves Retains activity under high organic contamination and hard water conditions Formalin-free 12

Ultra Circ Pro* Heavy duty circulation cleaner ULTRA RANGE: CIRCULATION AND TANK CLEANERS Rapid removal of milk protein and fats Low foam for effective CIP cleaning Gentle on rubber components and seals Easy rinsing capability Contains water softeners Ultra Circ Powerful pipeline cleaner High level of cleaning for rapid removal of milk protein and fats Low foam for effective CIP cleaning Easy rinsing capability Contains water softeners Designed to work in conjunction with Ultra Acid (p.14) as a total circulation cleaning system Ultra Circ DX* Chlorine-based tank cleaner For effective removal of protein and fat deposits from milk bulk tanks Non-foaming alkaline detergent Rapid cleaning action Designed to work in conjunction with Ultra Acid DX (p.14) as a total cleaning system for DX tanks Ultra Circ R Robotic milking system cleaner Chlorine free alkaline circulation cleaner 28% stabilised sodium hydroxide solution Low foaming Good cleaning and easy rinse Formulated using advanced water softening agents Effective in hard and soft water areas Designed to work in conjunction with Ultra Acid R (p.14) as a total cleaning system 13 *Coming soon, contact Neogen BioSecurity for further details.

Ultra Acid Pro Strong, heavy duty phosphoric acid descaler High level cleaning for rapid penetration and removal of mineral deposits Suitable for automatic in-place cleaning Effective removal of rust Effective in hard and soft water areas and in a wide range of water temperatures Ultra Acid Controlled foam CIP demineraliser Prevents build-up of mineral deposits on milking equipment and pipelines Contains detergents and water softeners for removal and prevention of milkstone deposits Based on phosphoric acid and chelating agents Suitable for automatic and manual use Designed to work in conjunction with Ultra Circ (p.13) as a total circulation cleaning system Ultra Acid DX Acid-based manual tank cleaner For effective removal of protein and fat deposits from milk bulk tanks Non-foaming acid detergent Rapid cleaning action Designed to work in conjunction with Ultra Circ DX (p.13) as a total cleaning system for DX tanks Ultra Acid R For use with robotic milking equipment Low foaming acidic circulation cleaner Formulated with advanced polymer detergent technology for improved cleaning Inhibits scale build up with regular use Effective in hard and soft water areas Designed to work in conjunction with Ultra Circ R (p.13) as a total cleaning system Ultra Acid MSR Strong milkstone remover High level cleaning for rapid penetration and removal of mineral deposits Suitable for hot or cold water ULTRA RANGE: CIRCULATION AND TANK CLEANERS 14

Thorough pipeline and bulk tank cleaning is essential in ensuring milk safety and quality. The Neogen BioSecurity Ultra Range is designed to perform in any system with exceptional results. Chlorinated and non-chlorinated products are available. PRODUCT POSITIONING Circulation cleaning - problem water Circulation cleaning - normal water Robotic milking cleaning Manual chemical dosing Bulk tank cleaning What do cleaning products do? Alkali Ultra Circ Pro Ultra Circ Ultra Circ R Cipsan Ultra Circ DX Alkali Removes fat and protein Acid Ultra Acid Pro Ultra Acid Ultra Acid R Sulphamic Acid Crystals Ultra Acid DX Acid Removes minerals e.g. milkstone Disinfectant Red Label Hypochlorite Red Label Hypochlorite Peraguard Red Label Hypochlorite Red Label Hypochlorite Disinfectant Kills micro-organisms Comments Water high in calcium and/or carbonates and/or bicarbonates Best for soft water from a mains supply Chlorine free washing Non automatic system Washing of bulk milk tanks Water Removes milk film 15

Dairy pipelines and equipment must be thoroughly cleaned to ensure milk quality and safety. The Neogen BioSecurity alkaline powder CIP cleaners are powerful cleaning formulations designed to retain activity, even in hard water and contain corrosion inhibitors to protect metal surfaces. Cipsan CIP chlorine release alkaline powder Provides powerful bactericidal activity High performance surfactants give superior rinsing capacity Contains corrosion inhibitors to protect metal surfaces Retains activity in hard water areas Cipsolve Alkaline CIP powder for cold cleaning of dairy pipelines and equipment High caustic content for heavy duty removal of protein and fat deposits Formulated for use at low cleaning temperatures Contains corrosion inhibitors to protect metal surfaces Formulated with water softeners to retain activity in hard water areas Non-foaming for easy rinsing Sulphamic Acid Crystals Acid crystals for the total cleaning of milking pipeline systems Suitable for use in hard or soft water areas Suitable for ABW system (Acidified Boiling Wash) POWDER CIP PRODUCTS 16

Foam Acid Blanket foam acidic cleaner and descaler High foaming action Highly concentrated Dissolves and emulsifies hard to remove deposits OTHER PRODUCTS Sureclean Highly alkaline caustic cleaner with high foaming properties For removal of heavy organic matter, grease deposits and contamination Red Label Hypochlorite 8% stabilised sodium hypochlorite disinfectant solution Low foaming formulation Can be used in automatic systems Washing Up Liquid Concentrated food industry detergent-degreaser Highly concentrated liquid for extra economy Liquid Filter Clean Caustic liquid for the cleaning of gauze filters BT Powder Alkaline pink powder for the manual cleaning of milk vessels 10% Hypochlorite 10% hypochlorite solution for final rinse, disinfection and general sanitisation Quatsan Versatile broad spectrum disinfectant suitable for automatic flush systems Ultra Acidine TS 17 All in one acidic iodine based milk tank spray, descalant and disinfectant

NEOGEN HAS A GLOBAL OFFERING IN ANIMAL SAFETY PRODUCTS WHICH INCLUDE: Reproduction Genomics Breeding diagnostics Semen collection Breeding supplies Apparel Biosecurity Speciality disinfectants Insect control Rodent control Safety equipment Protective wear and apparel Health and Wellness Water treatment Disease diagnostics Needles and syringes Wound and surgical supplies Castration and dehorning Hoof care Handling and identification Parlour Supplies Udder health Milk filters Milk testing OTHER NEOGEN ANIMAL SAFETY PRODUCTS Not all products are available in all countries, please contact Neogen BioSecurity biosecurity.sales@neogeneurope.com or Tel: +44(0)1706 344 797 18

Manufactured in the UK by Quat-Chem Ltd. 1-4 Sandfield Industrial Park, Dodgson Street, Rochdale, Greater Manchester, United Kingdom, OL16 5SJ animalsafety.neogen.com biosecurity.sales@neogeneurope.com Tel: +44(0)1706 344 797 EN ISO 9001:2015 QMS GMP ISO 22716:2007 NBR0006_0918