MATERIAL SAFETY DATA SHEET SECTION 1 - IDENTIFICATION OF PRODUCT AND COMPANY Pfizer Inc Pfizer Animal Health 235 East 42nd Street New York, NY 10017 Emergency telephone Hours of operation Telephone 1-866-531-8896 24 Hours 1-800-366-5288 Trade names DERMA-CLENS Product Name Therapeutic use Description DERMA-CLENS Cream Veterinary topical wound dressing Smooth, white viscous cream SECTION 2 - COMPOSITION Ingredient CAS Number Amount Benzoic Acid* 65-85-0 Proprietary Malic acid* 6915-15-7 Proprietary Methylparaben 99-76-3 Proprietary Propylene glycol 57-55-6 Proprietary Propylparaben 94-13-3 Proprietary Salicylic Acid* 69-72-2 Proprietary Stearyl Alcohol 112-92-5 Proprietary Steareth-2 CFTA 9005-00-9 Proprietary Steareth-21 CFTA 9005-00-9 Proprietary Xantan gum, Ph. Eur. 11138-66-2 Proprietary *Hazardous Note: Ingredient(s) indicated as hazardous have been assessed under US OSHA Hazard Communication Standard for workplace safety (29 CFR 1910.1200). SECTION 3 - HAZARDS IDENTIFICATION Signal word Statements of hazard Eye effects Skin effects Inhalation effects Ingestion effects CAUTION! MAY CAUSE EYE IRRITATION. May cause irritation based on components. Not expected to cause skin irritation. Not expected due to physical form. Ingestion of large quantities may result in headache, dizziness or sedation based on components. Page 1 of 5
SECTION 3 - HAZARDS IDENTIFICATION... continued Other potential health effects NOTE: Individuals who have impaired kidney function or skin disorders may be sensitive to the effects of this material. This document has been prepared in accordance with the US OSHA Hazard Communication Standard, which requires the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace. If your workplace is regulated by OSHA, this document must be used as a part of a complete hazard-training program. SECTION 4 - FIRST AID MEASURES Skin Eyes Inhalation Ingestion Remove contaminated clothing and shoes. Wash skin with soap and water. Wash clothing and thoroughly clean shoes before reuse. If irritation occurs or persists, get medical attention. Immediately flush eyes with water for at least 15 minutes. If irritation occurs or persists, get medical attention. Remove to fresh air. If not breathing, give artificial respiration.get medical attention. Get medical attention. Do not induce vomiting unless directed by medical personnel. Never give anything by mouth to an unconscious person. SECTION 5 - FIRE FIGHTING MEASURES Fire fighting instructions Extinguishing media Flash point Hazardous combustion products Wear approved positive pressure, self-contained breathing apparatus and full protective turn out gear. Evacuate area and fight fire from a safe distance. As for primary cause of fire. Non-flammable None known or expected. SECTION 6 - ACCIDENTAL RELEASE MEASURES General Small spill Large spill Review Sections 3, 8 and 12 before proceeding with clean up. Scoop or shovel spilled material into a labeled container for disposal. Clean spill area thoroughly. Scoop or shovel spilled material into a labeled container for disposal. Close container and move it to a secure holding area. Page 2 of 5
SECTION 7 - HANDLING AND STORAGE General handling Storage conditions Temperature range for storage Use in a well-ventilated area. Avoid contact with eyes. Keep in tightly sealed containers in a cool, dry, well-ventilated area away from food or containers of feed. Do not re-use containers. Avoid freezing conditions. Store at room temperature 20-25 C (68-77 F) SECTION 8 - EXPOSURE CONTROLS/PERSONAL PROTECTION Ventilation Respiratory protection Eye protection Skin protection Hand protection General room ventilation is adequate unless the process generates dust or fumes. Respirators are not required for the normal use of this mixture. Wear eye protection if eye contact is possible. Wear protective clothing with long sleeves to avoid skin contact. Wash hands and arms thoroughly after handling this mixture. Wear protective gloves to avoid repeated skin contact. SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical form Viscous cream Color White Molecular weight Mixture Molecular formula Mixture ph 2.8-3.6 (5% solution in water) Boiling point approx.100 C Melting point approx. 0 C Density No data available Vapor pressure No data available Water solubility Components are soluble in water Solvent solubility No data available SECTION 10 - STABILITY AND REACTIVITY Reactivity Stable Page 3 of 5
SECTION 10 - STABILITY AND REACTIVITY... continued Conditions to avoid Incompatibilities Hazardous decomposition products Hazardous polymerization Avoid direct sunlight, conditions that might generate heat and temperatures below 0 C. None identified None under normal conditions Will not occur SECTION 11 - TOXICOLOGY INFORMATION Toxicology summary There are no data for this formulation. The information included in this section describes the potential hazards of the individual ingredients. Acute toxicity Compound Type Route Species Dosage Malic acid Irritation Ocular Rabbit severe Irritation Dermal Rabbit moderate Stearyl Alcohol Irritation Ocular Rabbit 100mg/24h:Mld Irritation Dermal Rabbit 500mg/24h:Mld Eye Skin Inhalation May cause eye irritation based on components. See Acute toxicity table. Not expected to cause skin irritation based on experience with the normal use of this product. Ingestion Mutagenicity Subchronic effects Chronic effects/ carcinogenicity Carcinogen status Reproductive effects Teratogenicity The estimated LD50 in rats is greater than 2000 mg/kg based on toxicity of components and concentrations present. This mixture is not expected to be mutagenic, based on effects of individual components. None of the components of this formulation is listed as a carcinogen by IARC, NTP or OSHA. No components in this mixture produced adverse effects on male or female reproduction. No components in this mixture produced adverse effects on developing offspring. Page 4 of 5
SECTION 11 - TOXICOLOGY INFORMATION... continued At increased risk from exposure Individuals who have impaired renal function or skin disorders might be sensitive to the effects of this material. SECTION 12 - ECOLOGICAL INFORMATION Environmental overview The environmental characteristics of this mixture have not been fully evaluated. Releases to the environment should be avoided. SECTION 13 - DISPOSAL INFORMATION Disposal procedure Incineration is the recommended method of disposal for this material. Observe all local and national regulations when disposing of this mixture. SECTION 14 - TRANSPORTATION INFORMATION General shipping instructions Not regulated for transport under USDOT, EUADR, IATA, or IMDG regulations. SECTION 15 - REGULATORY INFORMATION EU Classification EU Labelling TSCA status SARA section 302 SARA section 313 California Proposition 65 Canadian WHMIS Not classified Not classified Not listed No No Not listed This product has been classified in accordance with the hazard criteria of the CPR and the MSDS contains all of the information required by the CPR. SECTION 16 - OTHER Disclaimer Pfizer Inc believes that the information contained in this Material Safety Data Sheet is accurate, and while it is provided in good faith, it is without a warranty of any kind, expressed or implied. Page 5 of 5