Protein Crystallization Starter Kit

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1. IDENTIFICATION OF THE PRODUCT AND OF THE COMPANY Product Name: Catalog Number: CS-401 Supplier: Jena Bioscience GmbH Loebstedter Strasse 71 07749 Jena, Germany Telephone: +49-3641-6285000 Fax: +49-3641-6285100 e-mail: info@jenabioscience.com WWW: www.jenabioscience.com 2. HAZARDS IDENTIFICATION The hazards identified with the are those associated with Acetic Acid : CAS# 64-19-7; Concentration 1.5 % w/v (250 mm) Sodium Hydroxide : CAS# 1310-73-2. Please refer to section 3 Composition/Information on Ingredients for hazard information on all substances appearing in this kit. Classification according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Skin irritation (Category 2) Eye irritation (Category 2) Labeling according to Regulation (EC) No 1272/2008 [EU-GHS/CLP] Pictogram Signal Word Warning Hazard Statement(s) H315 H319 Causes skin irritation. Causes serious eye irritation. Precautionary Statement(s) P264 P280 P302+P352 Wash hands thoroughly after handling. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN: Wash with plenty of soap and water. Page 1 of 6 www.jenabioscience.com Last update: Apr 17, 2015

P305+P351+P338 P332+P313 P337+P313 P362 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If skin irritation occurs: Get medical advice/attention. If eye irritation persists: Get medical advice/attention. Take off contaminated clothing and wash before reuse. 3. COMPOSITION/INFORMATION ON INGREDIENTS The classification and labeling in the table below corresponds to the pure chemicals, with the highest respective concentration given in the last column. Please refer to section 2 Hazards Identification for classification and labeling of the complete kit. Please refer to the Data Sheet for exact formula composition. The contains the following ingredients: Ingredient Name CAS # Pictogram H-Phrase P-Phrase C(max) Acetic Acid 64-19-7 H314;H226 P280;P305+ 250 mm P351+P338; P310 Lysozyme 9001-63-2 20 mg/ml PEG 5000 MME 9004-74-4 30% w/v Silicone Grease (Bayer) 100% Sodium Chloride 7647-14-5 20 % w/v Sodium Hydroxide (used to adjust the ph in the Sodium Acetate Buffer) 1310-73-2 H314 P280;P305+ P351+P338; P310 Page 2 of 6 www.jenabioscience.com Last update: Apr 17, 2015

4. FIRST AID MEASURES General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. 5. FIRE-FIGTHING MEASURES Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special protective equipment for fire-fighters Wear self contained breathing apparatus for fire-fighting if necessary. 6. ACCIDENTAL RELEASE MEASURES Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid dust formation. Avoid breathing vapors, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. 7. HANDLING AND STORAGE Handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Normal measures for preventive fire protection. Storage Store in cool place. Keep containers tightly closed in a dry and well-ventilated place. Page 3 of 6 www.jenabioscience.com Last update: Apr 17, 2015

8. EXPOSURE CONTROLS/PERSONAL PROTECTION Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Eye/face protection Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator. For higher level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance Form: liquid Colour: colourless Safety data ph: 4.0-5.2 Melting point: Boiling point: Flash point: Ignition temperature: Lower explosion limit: Upper explosion limit: Water solubility: 10. STABILITY AND REACTIVITY Storage stability Stable under recommended storage conditions. Page 4 of 6 www.jenabioscience.com Last update: Apr 17, 2015

Materials to avoid Strong oxidizing agents, strong acids, strong bases. Hazardous decomposition products Hazardous decomposition products formed under fire conditions. 11. TOXICOLOGICAL INFORMATION Acute toxicity Skin corrosion/irritation Serious eye damage/eye irritation Respiratory or skin sensitization Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity - single/repeated exposure Aspiration hazard Signs and Symptoms of Exposure To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Potential health effects Inhalation May be harmful if inhaled. Causes respiratory tract irritation. Ingestion May be harmful if swallowed. Skin May be harmful if absorbed through skin. Causes skin irritation. Eyes Causes serious eye irritation. 12. ECOLOGICAL INFORMATION Ecotoxicity Persistence and degradability Page 5 of 6 www.jenabioscience.com Last update: Apr 17, 2015

Bioaccumulative potential 13. DISPOSAL CONSIDERATIONS Product Observe all federal, state and local environmental regulations. Contaminated packaging Dispose of as unused product. 14. TRANSPORT INFORMATION ADR/RID Not dangerous goods IMDG Not dangerous goods IATA Not dangerous goods 15. REGULATORY INFORMATION This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. The substances and mixtures have been classified according to Regulation (EC) No. 1272/2008. 16. OTHER INFORMATION 2012 Jena Bioscience GmbH This material is sold for research purposes only. It is not intended for food, drug, household, agricultural or cosmetic use. Its use must be supervised by a technically qualified individual experienced in handling potentially hazardous chemicals. Users should make independent decisions regarding completeness of the information based on all sources available. The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Jena Bioscience GmbH shall not be held liable for any damage resulting from handling or from contact with the above product. See our website for our terms and conditions of sales. Page 6 of 6 www.jenabioscience.com Last update: Apr 17, 2015