Bio-expander ECO-BIO-COSMETICS. New Biorivolumetria line with natural active principles and Hyaluronic Acid

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Bio-expander ECO-BIO-COSMETICS New Biorivolumetria line with natural active principles and Hyaluronic Acid

Night & Day Creams Innovative cosmetics line Without Parabens - Colourings - Perfumes Bio-expander ECO-BIO-COSMETICS EC O B CERTIFICATO IO COSMESI 265 BC The Bio-expander Eco-Bio-Cosmetics comply with the rules as stated in the technical specifications on ECO-BIO-COSMETICS and are ICEA (the Italian ethical and environmental certification institute) certified, certificate n 265 BC The packaging materials are recyclable, while the paper is FSC certified, which stands for forest products and paper from responsibly managed forests. Expertise & Innovation for Beauty

Bio-expander Eco-bio-cosmetics line The new biorivolumetria cosmetics range is based on biological raw materials free of parabens, colourings and perfumes. It is suitable for dynamic people who wish to prevent and lessen the main causes of wrinkles and dry skin, such as environmental pollution, sudden meteorological changes, low temperatures, low humidity, chrono- and photoaging. The products of the Bio-expander Eco-Bio-Cosmetics range contain natural and biological substances, in line with the Ecology of Beauty a concept that is topical more than ever, and that affects various aspects of life, among which: health, beauty and environment friendliness. Using the Bio-expander creams every day activates the rejuvenation process and makes the skin look more vital and firmer; the use of these creams is highly recommended in Biorivolumetria treatments with Regenyal Idea Bio-expander, in order to maintain the results obtained with the treatment. Bio-expander ECO-BIO-COSMETICS

Properties of the Bio-expander cosmetics The Bio-expander Eco-Bio-Cosmetics strengthen the protective layer and re-structure the cutaneous barrier. Besides acting as anti-oxidants, they make the skin brighter and moisturize it. Among the ingredients there is Hyaluronic Acid obtained through bacterial bio-fermentation, and an extraordinary combination of active principles. The skin tissues naturally contain Hyaluronic Acid, which is responsible for important biological actions that determine the freshness and quality of skin. The concentration of Hyaluronic Acid diminishes with time and first aging signs become visible. The synergy of the functional active principles helps to: SLOW DOWN SKIN AGING PROTECT THE SKIN FROM ENVIRONMENTAL POLLUTION STIMULATE METABOLIC PROCESSES OF THE SKIN MAKE THE SKIN FIRMER PROTECT THE SKIN FROM CIGARETTE SMOKE Expertise & Innovation for Beauty

The Anti-age biorivolumetria line strengthened through a complex synergy of natural active principles Night & Day Creams Bio-expander ECO-BIO-COSMETICS

Bio-expander ECO-BIO-COSMETICS The Pomegranate combats free radicals and aging

The pomegranate seed oil It is a true cure-all for the skin and was chosen to be implemented as the main ingredient of the Bio-expander Eco-Bio-Cosmetics line, because: It s anti-aging action can combat the excess on free radicals It contains polyunsaturated fatty acids, vitamin E, flavonoids, phytohormones and phytosterols that naturally slow down the degenerative process of skin aging Has strong anti-oxidant properties and protects against UV-rays Hinders the effects caused by time and sunshine Night & Day Creams

Day Creams Contain protective active principles that can reduce the harmful effects of polluting substances, such as smog or cigarette smoke and protect from UV-rays. The effect that the daily use of Bio-expander Day Creams has on the skin is: MOISTURIZING FIRMING LIFTING The skin texture is also improved and the face looks refreshed. The day creams are soft and present a special combination of natural anti-oxidant substances, among which: ARTEMISIA A plant with anti-oxidant, anti-hyaluronidase and antiseptic properties. As it contains flavonoids and tannins this plant helps to prevent damages caused by free radicals and environmental pollution. UNDARIA PINNATIFIDA A seaweed native to Protection against cigarette smoke the Mediterranean. The extract of this seaweed is fabulous as it strengthens the immune system to fight damages caused by environmental pollution, and is very efficient in contrasting UVA rays, free radicals, smog, cigarette smoke and heavy metals. Protective activity (%) 60 50 40 30 20 10 0 +47% +37% +50% +40% +52% +44% In vitro test on fibroblasts 1 cigarette 2 cigarettes 1% 2% 4% DMSO - Cigarette smoke

Day Creams LIFTING CREAM EYE CONTOUR tube 15 ml Use in the morning on the area around the eyes, slightly massaging with the help of the applicator. MOISTURIZING CREAM INTENSIVE bottle 30 ml Use in the morning according to the needs, delicately massaging in circles until complete absorption. VITIS VINIFERA MERISTEMATIC CELL ESTRACT Grape stem cells rapidly act against free radicals thanks to highly bioavailable and regenerating active principles, synthesised by the stem cells. Laboratory tests show that the G-CELLS efficiently combat the species of radicals generated by factors of endogenous (stress, smoking, wrong nutrition) and exogenous (pollution, UV-rays etc.) origin. The anti-radical efficacy is proven by tests in vivo (+120% up to six hours after use).

Night Creams ANTI-WRINKLE CREAM EYE CONTOUR tube 15 ml Use in the evening on the area around the eyes, slightly massaging with the help of the applicator. VIVIFYING CREAM INTENSIVE bottle 30 ml After an accurate cleansing of the skin, apply the cream in the evening delicately massaging in circles, until complete absorption. These products are to be used before going to bed and kept on. Their action is: INTENSIVELY EUTROPHIC TONIFYING FIRMING NOURISHING In the morning the face will appear refreshed, and the epidermis firm and moisturized. The night creams make the wrinkles less deeper and make the face look firmer and brighter. The benefits are given by the synergy between HYALURONIC ACID and the extraordinary NATURAL ACTIVE PRINCIPLES, among which: SACCHARIDE ISOMERATE Scientific research shows the Saccharide Isomerate keeps the skin deeply hydrated for 72 hours, enhances the functioning of the cutaneous barrier and helps to normalize the exfoliation of the corneous layer, as shown in the macro-photographs on the side. Before the treatment 4 weeks after the treatment After only 2 weeks of treatment: THE SKIN IS SOFTER AND SMOOTHER THE ITCH IS REDUCED THE SKIN IS MORE SOUND

Night Creams IMPERATORIA A plant native to the Swiss Alps and the extract of which is used for the Bio-expander Night Creams, helps to maintain the skin young and healthy. It has antiedema, anti-oxidant and tonifying properties. BUDDLEJA DAVIDII A plant native to the territory of China, performs the following functions: ANTI-OXIDANT ANTIBACTERIAL ANTINFLAMMATORY PROTECTS AGAINST OZONE AND FREE RADICALS Thanks to the use of the extracts of this plant in cosmetics, it is possible to obtain anti-age compositions that help to protect the skin from stress and environmental pollution. In addition, Buddleja helps to prevent wrinkles and the diminishing of skin elasticity. Protection against ozone Ozone is the strongest oxidant in the air that significantly increases the oxidative stress. It attacks the skin s natural defence properties causing its early aging. The protective properties of Buddleja Davidii against the harmful effects of the ozone have been studied in vitro. The research was carried out studying the synthesis of the tumor necrosis factor- α (TNF-α) and the interleukins - 8 (IL-8) by human keratinocytes after having been exposed to the ozone: 45 TNF-α (pg/μg) production 40 35 30 25 20 15 10 5-46 -78-89 Control (Air Exposure) Control (Ozone Exposure) 1 mg NECTAPURE PF 5 mg NECTAPURE PF 10 mg NECTAPURE PF 0

Informational material for physicians CERTIFICATO ECO BIO COSMESI 265 BC IN RESPECT OF PEOPLE & NATURE Via Valtellina, 21 Member of CISQ Federation ISO 9001 Certified Quality System ISO 13485 Medical Devices - Certified Quality System ISO 14001 Certified Environmental System Certified Quality System Distributed by PHITOGEN HOLDING Spa www.phitogenspa.eu