GSP-T A powerful radical scavenger

GSP-T A powerful radical scavenger

GSP-T is a novel anti-oxidant complex containing water soluble grape seed procyanidins and oil soluble natural α,γ,δ Tocopherols (active d-form) stabilized in a transparent solution

What are procyanidins? Polyphenols Flavanoids Flavan-3-ols Catechin-and Epicatechin Oligomers

Inhibition of UV-A Induced Cell Toxicity in Squalene Nanoemulsions (1%) Cell number [%] 100 50 Synergistic effects with the combiation Grape Seed Extract and Tocopherols = GSP-T (100% inhibition of toxic effects induced by squalene peroxides) 0 untreated Treatment with 1% Squalene nanoemulsion (UV-A irradiated) without antioxidants + 0.5% Grape Seed Extract + 0.025% Tocopherol + 0.5% Grape Seed Extract + 0.025% Tocopherol (GSP-T)

GSP-T increases the Minimal Erythemal Dose (MED) 4 delta MED (sec) 3 2 1 0 Cream + 2.5% GSP-T Placebo untreated -1

GSP-T has instant anti-irritation effects redness [units] 10 9 8 7 6 5 4 3 2 1 0 Cream +2.5% GSP-T Placebo 0 15 30 45 60 [ min.]

Benefits of GSP-T in skin care Protects skin lipids from light-induced oxidative stress Prevents premature skin-aging Reduces and prevents skin irritation Increases microcirculation Increases the tolerance of the skin against UV-light

Hair is exposed to many detrimental effects UV-irradiation blow-drying sea water detergents

and wet hair is particularly open to attacks from ROS STRESS O 2 O 2 * Radical scaveneger GSP-T wet hair Damage of hair protein

Study design Hair sample washing/rinsing incubation in an aqueous solution of GSP-T or GSP-T in a finished product rinsing determination of extracted protein and peptides

GSP-T protects hair against damage induced by SDS-treatment and UV-irradiation 50 extracted proteins [ug/ml] 40 30 20 10 0 SDS SDS + UV control water + 2.5% GSP-T

GSP-T protects hair against damage induced by sea water and UV-irradiation 30 extracted proteins [ug/ml] 25 20 15 10 5 control water + 2.5% GSP-T 0 sea water sea water + UV

GSP-T prevents hair damage induced by blow drying 50 extracted proteins [ug/ml] 40 30 20 10 0 control 2.5% GSP-T

GSP-T protects hair against damage induced by blow drying 60 extracted protein [ug/ml] 50 40 30 20 10 control conditioner + 1.0% GSP-T conditioner + 1.5% GSP-T 0 5 cycles

Adsorption of Tocopherol on human hair 450 400 350 Tocopherol (ug/g hair) 300 250 200 150 100 50 0 0 10 20 30 60 Tocopherol min Tocopherol + Procyanidins (GSP-T)

GSP-T protects colour treated hair from fading 0.12 0.1 0.08 Rel. abs (484 nm) 0.06 0.04 0.02 0 5 min 10 min 20 min 30 min control water with 1% GSP-T water with 2.5% GSP-T incubation in shampoo (10% in water)

Benefits of GSP-T in hair care Protects hair protein from oxidative stress Protects hair from environmental stress Protects hair from detergents, salt water Protects color treated hair from fading Reduces heat damage induced by blow-drying.in leave-on and rinse-off products

USPs Natural ingredient (herbal extract) Successful skin care concept adapted for hair care Concept based on clear scientific background Proven effects in standard assays and new tests and active in leave-on and rinse-off products

GSP-T A breakthrough in protection for skin and hair Most effective protection from oxidative and environmental stres. based on natural actives

GSP-T à votre santé

Application of GSP-T in cosmetics 0.1-0.5% protection of sensitive compounds in the formulation 0.5-2.5% protection of skin against oxidative stress sun care products anti-aging products hair treatment (shampoo, conditioner, hair tonics) oily skin treatment