Product Catalog Pathology Histology Dermatology Mohs

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Worldwide supplier of high quality tissue marking dyes. Product Catalog Pathology Histology Dermatology Mohs

Welcome / About Welcome Dear Colleague, It is with great pleasure that we provide this catalog of products developed in collaboration with Dr. Terence Davidson and the laboratory community, featuring the well established Davidson Marking System dyes. We are pleased to bring new products to you in the form of our new Lime color, stainless steel tray, tray for 8 oz. dyes, and Davidson Cryocup System options. In addition, we introduce two new lines to you related manual staining equipment from Integrated Medical Solutions and microtome blades from C.L. Sturkey Inc. When we work together, we are able to create efficient processes through the innovation of new products, design and technique. We have timed the release of this catalog with the debut of a brand new website. Please visit us at www.bradleyproducts.com soon and experience a fresh new look with more userfriendly features for learning as well as purchasing. With thanks for your continued support, Jeffrey A. Olson, President Bradley Products, Inc. About Us In 1984, Bradley Products, Inc., in collaboration with Dr. Terence Davidson, developed the original set of dyes used for tissue orienting with the Mohs procedure. The Davidson Marking System dyes eliminated the need for suture orienting and made tissue marking processing more efficient and accurate. For 30+ years, the following commitments have kept Bradley Products, Inc. at the forefront of the tissue marking dye industry worldwide: a devotion to product quality and business integrity a focused expertise allowing for excellence above and beyond competitors continuous development of additional colors, sizes, sets, accessories close communication with customers and understanding of current needs collaboration with relevant colleagues in the industry. an awareness for the environment, using sustainable and recyclable products wherever possible The world can rely on Bradley Products, Inc. to continue with excellence far into the future. The top 20 cancer hospitals in the US* use our products and rely on our company. You can too. It is our commitment. * Top 20 cancer hospitals listed by US News and World Report 2017. 2 Bradley Products, Inc. www.bradleyproducts.com

Davidson Marking System... 4-5 Davidson Marking System Complete Sets... 6-7 Davidson Marking System Individual Trays...8 Davidson Marking System Individual Dyes...9 Davidson Cryocup System...10-11 Accessories...12-13 Related Equipment (IMS and C.L. Sturkey )...14-15 For complete product, pricing and safety information For educational video or printed instructions For connecting, feedback, questions and suggestions For connection to our International resellers Please visit our website or contact us directly. Index Index / Contact Information / Ordering Information Contact / Place an Order Website www.bradleyproducts.com Email dms@bradleyproducts.com Phone 1-800-325-7785 (toll-free from the US and Canada) 001-952-881-1430 (International) Fax 001-952-881-1873 3

The Davidson Marking System The Original Tissue Marking System The Davidson Marking System is the original tissue marking system, first developed for the Mohs technique, currently suitable for a variety of laboratory applications requiring orientation of tissue specimens. These specifically formulated tissue dyes: are suitable for both fresh and frozen tissue samples can be used pre- or post- fixation adhere to tissue throughout processing are clearly visible under the microscope can be easily distiguished from each other are economical and space-efficient 4 Bradley Products, Inc. www.bradleyproducts.com

Use of The Davidson Marking System Dyes 1. Shake tissue dye well before and throughout each use. 2. Carefully blot tissue to remove excess moisture. 3. Apply dye directly to desired portion of tissue using an applicator stick or brush. Do not apply excess dye as this will prolong drying time. 4. Recap bottle promptly to prevent evaporation. 5. Allow dye to dry completely (1-2 minutes). Once dry, the dye is permanently bonded to the tissue. 6. No mordant is necessary, but can be used if desired. 7. Once dry, the processing of the tissue can be performed. The Davidson Marking System Pictures of orienting and sectioning using The Davidson Marking System. Pictures of slides of tissue marked with The Davidson Marking System dyes, sliced and viewed under a microscope at various magnifications. 5

Davidson Marking System Complete Dye Sets Davidson Dye Sets are Complete Davidson Marking System Complete Sets come with everything you need for tissue marking. These sets can be placed on your lab work station ready to use. Small and compact, they are easily portable and save space. Each set includes: Davidson dyes in various sizes and colors holding tray in plastic, wood or stainless steel applicator sticks instructions for use Introducing NEW Stainless Steel Tray By popular request, we introduce a NEW stainless steel tray that holds five (5) 2 oz. bottles of Davidson dye. We also introduce this NEW 5-Color Set. NEW 2401-S 5-Color 2 oz Set in stainless steel tray. 6 Bradley Products, Inc. www.bradleyproducts.com

2406-W DMS 6-color 2 oz. Set in wood tray Sets come with 3, 5, 6, or 7 colors and with 3cc, 1 oz. or 2 oz. dyes. You have options for tray material as well. Complete sets offer everything needed in one convenient location, in a small space, be it on the lab work station, shelf, or mobile unit. The bottles of dye can be repurchased in their size to restock the set, or can be filled from our 8 oz. size refill bottle. On the next pages, see how to select individual elements best suited for your specific lab and procedure needs. A Variety of Complete Sets 1207-P DMS 7-Color 1 oz. Set in plastic tray 1007-P DMS 7-Color 3cc Set in plastic tray 2403-P DMS 3-Color 2 oz. Set in plastic tray Davidson Marking System Complete Dye Sets W=wood tray, P=plastic tray, S=stainless steel tray g=green, y=yellow, bk=black, r=red, bl=blue, o=orange, v=violet 2407-W, 2407-P 7-Color Sets of 2 oz. bottles of marking dye (g, y, bk, r, bl, o, v) 2406-W, 2406-P 6-Color Sets of 2 oz. bottles of marking dye (g, y, bk, r, bl, o) 2401-W, 2401-P, and NEW 2401-S 2403-W, 2403-P 5-Color Sets of 2 oz. bottles of marking dye (g, y, bk, r, bl) (2401-S in NEW stainless steel tray) 3-Color Sets of 2 oz. bottles of marking dye (customer selects colors) 1207-W, 1207-P 7 Color Sets of 1 oz. bottles of marking dye (g, y, bk, r, bl, o, v) 1007-P 7-Color Set of 3cc bottles of marking dye (3 ea of g, y, bk, r, bl, o, v) Phone: 800-325-7785 001-952-881-1430 7

Davidson Marking System Individual Trays Three (3) Tray Materials WOOD Our original tray made out of high quality redwood. PLASTIC Made of heavy marble-like plastic, cleans up nicely and stays put on work surface. NEW! STAINLESS STEEL By popular request, we introduce our NEW stainless steel tray for five (5) 2 oz. bottles of Davidson dye. The option to obtain individual trays and dyes allows you to put together the elements specifically needed in your laboratory. Whatever size, quantity or color you desire, it is possible. 1877-W 7-Hole wood tray for 2 oz. bottles 1833-P 3-Hole plastic tray for 2 oz. bottles NEW 2401-S 5-Hole stainless steel tray for 2 oz. bottles NEW 1888-P 5-Hole plastic tray for 8 oz. bottles W=wood tray, P=plastic tray, S=stainless steel tray 1877-W, 1877-P 1866-W, 1866-P 1873-W, 1873-P, and NEW 1873-S 1833-W, 1833-P 1817-W, 1817-P 7-Dye Trays for 2 oz. bottles of dye 6-Dye Trays for 2 oz. bottles of dye 5-Dye Trays for 2 oz. bottles of dye (1873-S is NEW Stainless Steel Tray) 3-Dye Trays for 2 oz. bottles of dye 7-Dye Trays for 1 oz. bottles of dye 1807-P 21-Dye Tray for 3cc bottles of dye 1888-W, 1888-P NEW 5-Dye Trays for 8 oz. bottles of dye The trays are designed with holes for the dyes as well as holes that will hold a few applicator sticks making them immediately available for use. Many of the trays also have a small channel space in which to place the bottle caps. Tray labels are printed with a ruler for measuring specimens and quickly recording measurements during mapping. All tray materials are recyclable. 8 Bradley Products, Inc. www.bradleyproducts.com

GREEN BLUE 8 Colors 4 Sizes Unlimited Combinations YELLOW ORANGE 8 oz 2 oz 1 oz 3cc BLACK VIOLET RED LIME COLOR CHOICE Surgeons and pathologists may differ, one from another, in their selection of colors. This is usually personal preference, but may also be affected by specific lab procedures. VISCOSITY Viscosity varies naturally from color to color and may also govern dye choice. SAMPLES Unsure? Ask for our 8-color sample pack and try all colors. It contains eight (8) 3cc bottles of dye, one (1) each of our eight (8) colors. Davidson Marking System Individual Dyes NEW! LIME COLOR We get many requests for additional colors. Our ability to add new colors depends on a pigment passing our high standard of quality. Our newest LIME color adheres well and is easily distinguishable from our green dye under the microscope, thus broadening orienting options. Samples are available. Replace (x) with: 1=green, 2=yellow, 3=black, 4=red, 5=blue, 6=orange, 7-violet, 8=lime NEW 1013-A Jar of 40 3cc dye, assorted colors 3408-(x) 1163-(x) 1101-(x) 1013-(x) 8 oz. dyes (1 ea.) 2 oz. dyes (1 ea.) 1 oz. dyes (1 ea.) 3cc dyes (jar of 40 3cc bottles) 1013-A NEW! 3cc dyes (jar of 40), assorted colors. (5 each of g, y, bk, r, bl, o, v, l) SAMPLE Sample pack of 8 3cc bottles - all colors 9

Davidson Cryocup System Why Choose The Cryocup System? The Davidson Cryocup System has been developed to work alongside your existing equipment such as your microtome and cryostat. There are Cryocup Systems compatible with Leica, Microm (Avantik), Sakura and Thermo-Shandon equipment. The Cryocup System: facilitates perfect flattening of oriented tissue specimens during freezing, quickly producing a sample ready for immediate slicing with little or no facing required. can quickly fill in when your cryostat loses temperature, helping to avoid work interruption. is portable and economical, and therefore useful for lab work in the field or satellite lab, saving space at the lab work station. Use of The Cryocup System This process can be done in less then one minute per specimen: 1. Place dyed specimen into a Cryocup. 2. Fill with OCT up to the ledge. 3. Place a Cryo Chuck (or one you already have) on top of the specimen. 4. Place Cryocup in the Cryo Holder and lower the cover onto the Cryocup. 5. Dip Cryocup into liquid nitrogen for freezing (10 seconds), 6. Drain. Remove Cryocup. 7. Warm Cryocup slightly to release tissue specimen. Notice perfectly flattened specimen, already faced, mounted on chuck and ready for slicing. 10 Bradley Products, Inc. www.bradleyproducts.com

The Davidson Cryocup System makes the work of frozen tissue preparation: more efficient more accurate more portable more economic We encourage you to visit our web site, navigate to the video instruction page and find the video showing how the Cryocup improves your lab. Keep your samples frozen on the chucks and in the Cryocup, placed in our stainless steel tray inside your cryostat. (30mm cups fit in 2401-S tray). Guidelines for Choosing Davidson Cryocup Products B = BPI: Compatible with most Leica, Sakura and old style Thermo- Shandon equipment M = Microm (Avantik): Compatible with Microm equipment L = Leica: Specifically designed for the Leica 40mm chuck Size: Base size choice on the size of chuck you may already have with your equipment, or the size of specimens you typically process. Davidson Cryocup System Cryo Sys 30B Cryo Sys 30M Cryo Sys 40B Cryo Sys 40L Cryo Sys 40M Cryo Sys 50B Cryo Holder 30B Cryo Holder 30M Cryo Holder 40/50B Cryo Holder 40M Cryocup 30MB Cryocup 40B Cryocup 40M Cryocup 50B Cryo Chuck 30 Cryo Chuck 40 Cryo Chuck 50 Cryocup Complete System Includes holder, 3 Cryocups, nitrogen reservoir, water basin. (chucks are not included) 30mm system for BPI and Leica 30m chucks 30mm system for Microm 30mm chucks 40mm system for BPI 40mm chucks NEW 40mm system for Leica 40mm chucks 40mm system for Microm 40mm chucks 50mm system for BPI 50mm chucks (compatible with Leica) Cryocup Holder (includes dipper, cover and clip) 30mm holder for BPI, Leica (small cover, small hole) 30mm holder for Microm (small cover, large hole) 40-50mm holder for BPI, Leica (large cover, small hole) 40mm holder for Microm (large cover, large hole) Cryocup 30mm cup for BPI, Leica, Microm 30mm chucks 40mm cup for BPI, Leica 40mm chucks 40mm cup for Microm 40mm chucks 50mm cup for BPI 50mm chucks 30mm chuck 40mm chuck 50mm chuck Cryocup Chucks 11

Accessories Quality Accessories Make all the Difference! We understand the importance of good quality tissue marking dyes in laboratory processing. We also understand the importance that quality tools and accessories play in the accuracy and efficiency of lab work. Select un-tipped or tapered sticks for the smallest specimens and brushes for the largest specimens. Choose cassette papers to keep needle biopsy specimens intact in a cassette during processing. Davidson Small Specimen Kit 6601 Davidson Small Specimen Kit 6605 Cassette Papers The Davidson Small Specimen Dyes are formulated for two main purposes: 1. Aid in locating a small specimen after processing. Prior to processing a small needle or punch biopsy, color it completely using the Davidson Small Specimen dye. Wrap it in a cassette paper before placing it in the cassette. When processing is complete, it will be much easier to locate it in the cassette paper. 2. Process multiple small specimens together. Make small tissue processing 3x faster by dying up to three small specimens different colors and processing them together. They are easily distinguishable after processing. To further speed up the process, consider a processing basket that holds multiple cassettes (Related Equipment, pg. 13-14). 12 Bradley Products, Inc. www.bradleyproducts.com

Applicator Sticks / Brushes / Brush Caps A variety of applicators are offered. Using the right applicator when applying dye to tissue for orienting increases accuracy. Accessories The Brush Caps fit on our 2 oz dye bottles making an applicator always available. 8553 un-tipped applicator sticks 8554 Brush Caps for 2 oz. bottles 8556 cotton-tipped, rounded applicator sticks 8555 cotton-tipped, tapered applicator sticks 7399 wide mouth jar and brushes 8557 1 brush For large specimens, consider Item 7399 which includes a 16 oz empty wide mouth jar and brushes. Pour Davidson dye into the wide mouth jar making it more accessible by the larger brush. 8558 2 brush 6601 Davidson Small Specimen Kit 3-1 oz. bottles of Small Specimen dye (g, r, bl) in tray with cassette papers 8553 500 applicator sticks (10 packs of 50) 8554 Brush caps for 2 oz bottles (bag of 10) 8555 250 tapered end cotton tipped applicator sticks (10 packs of 25) 8556 250 rounded end cotton tipped applicator sticks (10 packs of 25) 8557 1 inch brushes (bag of 25) 8558 2 inch brushes (bag of 25) 7399 10-1 inch brushes + 1-16 oz empty wide mouth jar (for use with larger specimens) 6605 500 cassette papers (refill) Phone: 800-325-7785 001-952-881-1430 13

NEW Related Equipment New Equipment Lines IMS (Integrated Medical Solutions) and C.L. Sturkey Inc. We are happy to introduce new lines of equipment related to the process of tissue marking. Collaborations with Integrated Medical Solutions and C.L. Sturkey makes these lines a reality. Many of these items bridge the gap between the large, expensive equipment, and the simpler, manual procedures occurring in the mobile laboratory industry. As always, your feedback regarding these new products is invited. IMS Manual Staining Equipment 8701 IMS Manual Staining System This portable and compact manual staining system has twelve (12) interchangeable wells in a metal tray. It is compatible with both slide racks offered, one plastic, one stainless steel. 8730 IMS Slide Rack, 25 capacity, stainless C.L. Sturkey Microtome Blades 8559-SL 8559-SH 8559-EL 8559-EH 8559-IL 8559-IH Silver Low Profile blades Silver High Profile blades Extremus Low Profile blades Extremus High Profile blades Infinity Low Profile blades Infinity High Profile blades Guidelines for choosing Sturkey blades: 8559 Sturkey blades, pkg of 50 S Silver (standard) E Extremus (for hard & soft tissue) I Infinity (durable, triple faceted cutting edge) H High (wide) L Low (narrow) 14 Bradley Products, Inc. www.bradleyproducts.com

For complete descriptions and pictures of all of our new Related Equipment offerings, please visit us at our website or contact us directly. Watch for additions to this page in the future as we seek to expand further. 8740 IMS Heat Extractor with Knob / 8741 IMS Heat Extractor Small IMS Slide Baskets / Racks / Holders NEW Related Equipment 8710 IMS Tissue Processing Basket (Sakura-type) 8750 IMS Fine Needle Aspiration Device 8720 IMS Slide Basket 30 capacity stainless / 8721 IMS Staining Dish and Cover for 8720 IMS Manual staining, while compact and portable, can often seem tedious. Having the right manual equipment can create more efficient work. Each new product on this page helps to maximize accuracy, speed, economy, and portability. We hope the fact that they are now offered alongside our established products will also make ordering easier for you. 8701 IMS Manual Staining System, 12 wells 8710 IMS Tissue Processing Basket (Sakura-type) 8711 IMS Tissue Processing Basket (Leica-type) 8720 IMS Slide Basket, 30 capacity, stainless 8721 IMS Staining Dish with Cover for Slide Basket 8730 IMS Slide Rack, 25 capacity, stainless 8731 IMS Slide Rack 25 capacity, plastic 8740 IMS Heat Extractor, stainless with knob 8741 IMS Heat Extractor, stainless, small 8742 IMS Heat Extractor, stainless, tall 8750 IMS Fine Needle Aspiration Device 8760 IMS PM Kit for Leica Knife Holder 8770 IMS Forceps 6, serrated tip 8799 IMS Grossing Board 15

Worldwide supplier of high quality tissue marking dyes. I was still using sutures because the dyes we previously used didn t stick. Then I heard about Bradley Products, Inc. and The Davidson Marking System tissue dyes. Finally something that works. And their customer service is great! Ellie, Surgical Tech Davidson, The Davidson Marking System and Cryocup are registered trademarks of Bradley Products, Inc. Bradley Products, Inc 1700 West 94th Street, Bloomington, MN 55431-2300 US Phone: 800-325-7785, 001-952-881-1430 Fax: 952-881-1873 Email: dms@bradleyproducts.com www.bradleyproducts.com Made in USA US Federal ID 41-0979462 000577 091517