SAFETY DATA SHEET according to Regulation (EU) 2015/830

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SAFETY DATA SHEET according to Regulation (EU) 205/830 /7 SECTION : Identification of the substance/mixture and of the company/undertaking.. Product identifier date 208-09-0 Product name Product code NCM004, 7425, LAB088.2. Relevant identified uses of the substance or mixture and uses advised against Product Use.3. Details of the supplier of the safety data sheet Company Address Web [SU3] Industrial uses: Uses of substances as such or in preparations at industrial sites; [PROC5] Use as laboratory reagent; Neogen Corporation 620 Lesher Place Lansing MI 4892 USA www.neogen.com Telephone 57-372-9200/800-234-5333 Email.4. Emergency telephone number Emergency telephone number -800-234-5333 Further information Manufactured By: regulatorysupport@neogen.com Neogen Corporation 740 East Shiawassee Lansing, MI 4892 U.S.A. Neogen Corporation Quest Park-Moss Hall Road Heywood Lancashire BL97JJ UK. Hotline(s): Medical: United States (-800-498-5743), International (-65-523-038). Spill/CHEMTREC: United States (-800-424-9300), International (-703-527-3887). SECTION 2: Hazards identification 2.. Classification of the substance or mixture 2..2. Classification - EC 272/2008 2.2. Label elements The product is classified as non hazardous. P0 - If medical advice is needed, have product container or label at hand. P02 - Keep out of reach of children. P50 - Dispose of contents/container to an appropriate waste site or reclaim (in accordance with local/regional/national/international regulation). Copyright 209 ChemSoft. All rights reserved. 209-02-2

date 2/7 208-09-0 2.2. Label elements Hazard Statement No Significant Hazard 2.3. Other hazards Other hazards This product is not identified as a PBT substance. SECTION 3: Composition/information on ingredients 3.2. Mixtures EC 272/2008 Chemical Name Index No. CAS No. EC No. REACH Registration Number Conc. (%w/w) Classification Sodium Cholate 36-09- 206-643-5-0% Skin Irrit. 2: H35; Eye Irrit. 2: H39; Sodium Deoxycholate 302-95-4 206-32-7-0% Acute Tox. 4: H302; Skin Irrit. 2: H35; Eye Irrit. 2: H39; SECTION 4: First aid measures 4.. Description of first aid measures Inhalation Eye contact Skin contact Ingestion 4.2. Most important symptoms and effects, both acute and delayed Inhalation Eye contact Skin contact Ingestion Full text for all Risk Phrases mentioned in this section are displayed in Section 6. In case of accident by inhalation: remove casualty to fresh air and keep at rest. Contact lenses should be removed. Rinse immediately with plenty of water for 5 minutes holding the eyelids open. After contact with skin, take off immediately all contaminated clothing, and wash immediately with plenty of water. Keep the affected person warm and at rest. DO NOT INDUCE VOMITING unless advised to do so by a doctor. Rinse mouth thoroughly. May cause irritation to respiratory system. May cause irritation to eyes. May cause irritation to skin. Ingestion may cause nausea and vomiting. 4.3. Indication of any immediate medical attention and special treatment needed Inhalation Eye contact Skin contact Ingestion SECTION 5: Firefighting measures 5.. Extinguishing media 5.2. Special hazards arising from the substance or mixture 5.3. Advice for firefighters Seek medical attention if irritation or symptoms persist. Seek medical attention if irritation or symptoms persist. Seek medical attention if irritation or symptoms persist. If you feel unwell, seek medical advice (show the label where possible). Use as appropriate: Carbon dioxide (CO2), Alcohol resistant foam, Powder. Burning produces irritating, toxic and obnoxious fumes. In case of fire and/or explosion do not breathe fumes. Wear suitable respiratory equipment when necessary. Wear suitable protective clothing, gloves and eye/face protection. Copyright 209 ChemSoft. All rights reserved. 209-02-2

3/7 SECTION 6: Accidental release measures 6.. Personal precautions, protective equipment and emergency procedures No precautions required to be mentioned. 6.2. Environmental precautions date 208-09-0 6.3. Methods and material for containment and cleaning up 6.4. Reference to other sections SECTION 7: Handling and storage 7.. Precautions for safe handling Do not empty into drains; dispose of this material and its container in a safe way. Avoid raising dust. Sweep up. Dispose of in compliance with all local and national regulations. See section 8 & 3 for further information. 7.2. Conditions for safe storage, including any incompatibilities 7.3. Specific end use(s) Do not eat, drink or smoke in areas where this product is used or stored. Wash hands after handling the product. Store at temperatures between 2 C and 30 C. Store in original container. Keep container tightly closed and dry. Protect from moisture. See section.2 for further information. SECTION 8: Exposure controls/personal protection 8.. Control parameters 8.2. Exposure controls Exposure above the recommended occupational exposure limit (OEL) may cause adverse health effects. 8.2.. Appropriate engineering controls 8.2.2. Individual protection measures Eye / face protection Skin protection - Handprotection Skin protection - Other Respiratory protection Thermal hazards 8.2.3. Environmental exposure controls Ensure adequate ventilation of the working area. Not normally required. Use as appropriate:. safety glasses with side-shields. Chemical resistant gloves. Wear suitable protective clothing. Do not breathe dust. In case of insufficient ventilation, wear suitable respiratory equipment. Avoid release to the environment. Refer to special instructions/safety data sheets. See section 7 for further information. SECTION 9: Physical and chemical properties 9.. Information on basic physical and chemical properties Copyright 209 ChemSoft. All rights reserved. 209-02-2

4/7 9.. Information on basic physical and chemical properties Appearance Powder Colour Beige Odour Characteristic Odour threshold Not applicable. ph 7.2-7.6 Melting point No data available Freezing Point No data available Initial boiling point No data available Flash point Not applicable. Evaporation rate No data available Flammability (solid, gas) Not applicable. Vapour pressure Not applicable. Vapour density Not applicable. Relative density No data available Fat Solubility No data available Partition coefficient No data available Autoignition temperature Not applicable. 9.2. Other information Viscosity No data available Explosive properties Not applicable. Oxidising properties Not applicable. Solubility No data available Conductivity No data available Surface tension No data available Gas group Not applicable. Benzene Content No data available Lead content No data available VOC (Volatile organic compounds) SECTION 0: Stability and reactivity 0.. Reactivity 0.2. Chemical stability 0.3. Possibility of hazardous reactions 0.4. Conditions to avoid 0.5. Incompatible materials No data available 0.6. Hazardous decomposition products Stable under normal conditions. See section 7 for further information. Will not decompose if stored and used as recommended. No precautions required to be mentioned. Stable under normal conditions. No precautions required to be mentioned. No precautions required to be mentioned. date 208-09-0 Carbon oxides, Organic materials may be formed in fire conditions. Fire will produce dense black smoke. Copyright 209 ChemSoft. All rights reserved. 209-02-2

5/7 SECTION : Toxicological information.. Information on toxicological effects date 208-09-0 Acute toxicity Skin corrosion/irritation Serious eye damage/irritation Respiratory or skin sensitisation Germ cell mutagenicity Carcinogenicity Reproductive toxicity STOT-single exposure STOT-repeated exposure Aspiration hazard Repeated or prolonged exposure..2. Mixtures..3. Hazard Information..4. Toxicological Information..5. Hazard Class..6. Classification Criteria See section 3 for further information. May cause irritation to skin. See section 3 for further information. May cause irritation to eyes. See section 3 for further information. May cause sensitisation by inhalation and skin contact. See section 3 for further information. See section 3 for further information. See section 3 for further information. See section 3 for further information. See section 3 for further information. No data available No Significant Hazard. Not applicable...7. Information on likely routes of exposure Skin contact. Inhalation...8. Symptoms related to the physical, chemical and toxicological characteristics..9. Delayed and immediate effects as well as chronic effects from short and long-term exposure..0. Interactive effects... Absence of specific data No data available...2. Mixture versus substance information..3. Other information Not applicable. Not applicable. Copyright 209 ChemSoft. All rights reserved. 209-02-2

6/7 SECTION 2: Ecological information 2.. Toxicity No data available 2.2. Persistence and degradability 2.3. Bioaccumulative potential date 208-09-0 Partition coefficient Violet Red Bile Glucose Agar No data available (ISO) 2.4. Mobility in soil 2.5. Results of PBT and vpvb assessment 2.6. Other adverse effects No data available. SECTION 3: Disposal considerations 3.. Waste treatment methods Dispose of in compliance with all local and national regulations. Disposal methods Disposal of packaging Contact a licensed waste disposal company. Do not flush into surface water. This material and its container must be disposed of in a safe way. Empty containers can be sent for disposal or recycling. Containers can be recycled if in compliance with local and national regulations. Do NOT reuse empty containers. SECTION 4: Transport information 4.. UN number 4.2. UN proper shipping name 4.3. Transport hazard class(es) 4.4. Packing group 4.5. Environmental hazards 4.6. Special precautions for user Copyright 209 ChemSoft. All rights reserved. 209-02-2

7/7 4.7. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code SECTION 5: Regulatory information 5.. Safety, health and environmental regulations/legislation specific for the substance or mixture date 208-09-0 Regulations 5.2. Chemical safety assessment SECTION 6: Other information Other information COMMISSION REGULATION (EU) 205/830 of 28 May 205 amending Regulation (EC) No 907/2006 of the European Parliament and of the Council on the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH). Text of Hazard Statements in Section 3 DISCLAIMER: The information and recommendations set forth herein ("Information") are presented in good faith and believed to be correct as of the date issued. No representation is made regarding the completeness or accuracy of the Information. Further, because of the many factors that affect the use of this product, the Information is supplied upon the condition that the person(s) receiving it will make their own determination regarding its suitability for their own unique purpose(s), prior to use. Except as expressly stated herein, NO WARRANTIES, GUARANTEES, OR REPRESENTATIONS OF ANY KIND, EXPRESS OR IMPLIED, INCLUDING, BUT NOT LIMITED TO, IMPLIED WARRANTY OF MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE, COURSE OF PERFORMANCE, USAGE OF TRADE, OR RESULTS TO BE OBTAINED BY USE OF THIS PRODUCT are made with respect to this product or use of this product. The product covered is furnished "as is" and only subject to the warranties herein provided, no liability is assumed resulting from the use of this product. This document differs from the previous version in the following areas:. 2-2.. Toxicity. Skin Irrit. 2: H35 - Causes skin irritation. Eye Irrit. 2: H39 - Causes serious eye irritation. Acute Tox. 4: H302 - Harmful if swallowed. Copyright 209 ChemSoft. All rights reserved. 209-02-2