MAXIMUM POWER TRIPLE MODE Q-SWITCHED, LP AND QLP ND:YAG LASER SYSTEM 3 PULSE DURATIONS 4 DISTINCTIVE WAVELENGTHS MULTIPLE INDICATIONS

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ALMA-Q MAXIMUM POWER TRIPLE MODE Q-SWITCHED, LP AND QLP ND:YAG LASER SYSTEM 3 PULSE DURATIONS 4 DISTINCTIVE WAVELENGTHS MULTIPLE INDICATIONS

INTRODUCTION ALMA-Q presents the most powerful triple mode Nd:YAG laser treatment solution available, featuring Q-switched, Long Pulsed and Quasi-Long Pulsed modes on a single, dedicated platform. With Double Pulse technology offering up to 2,000mj per pulse; an extraordinarily short pulse width of 7nsec; unique technological innovations including depth control and fractional delivery and additional options of working with both the Long Pulsed and Quasi-Long Pulsed Nd:YAG 1064nm laser, ALMA-Q is unmatched in its power and versatility for treating a wide range of aesthetic dermal indications.

THE Q-SWITCHED LASER ADVANTAGE The Q-Switched Laser The high powered Q-switched laser is the most effective method for removing natural or artificial pigmentation, while minimizing the risk of damage to surrounding tissue. ALMA-Q s fractional capabilities further extend the potency of the Q-switched laser, opening the door to additional treatment possibilities, including challenging skin imperfections associated with aging. Epidermis 2. Due to photoacousric effect pigment particles are selectively fragmented ALMA-Q delivers photo acoustic shockwaves to the 3. Fragmented pigment particles are carried away by phagocytes target area through high laser intensities in ultra-short nanosecond pulses. This method creates controlled dermal wounds via a mechanical Q-Switched effect - a unique mechanism of action that achieves optimal results for various indications without causing thermal damage or coagulation in the surrounding tissue. Dermis 1. Pigment in the skin 1 2 3 Four Distinct Wavelengths ALMA-Q offers four distinct wavelengths targeting the full spectrum of ink colors found in multi colored tattoos. Absorption Coeffcient (1/cm) 10 5 10 4 10 3 10 2 10 1 10-0 10-1 10-2 10-3 10-4 Laser Absorption and tissue Penetration Melanin Hemoglobin Protein Scatter Water 1 1 10 Wavelength (micrometers) Single and Double Pulse Technologies ALMA-Q offers energy delivery in both Single Pulse and Energy intensity Double Pulse modes. Double Pulse technology disperses the laser energy into two consecutive pulses, mitigating peak power while delivering maximum energy of up to 2J per pulse. By creating a flat-top beam, maximum energy may be delivered evenly over the skin without risking epidermal injury. Both Single and Double Pulse modes are available in all ALMA-Q QSW wavelengths including: 1064nm, 532nm, 585nm and 650nm. µ-sec 135 1st pulse 1,000 mj, 7 ns 2nd pulse 1,000 mj, 7 ns Pixel Fractional Q-Switched Laser with Depth Control ALMA-Q s Pixel handpiece offers the first fractional Q-switched laser for skin rejuvenation that features unique depth control capabilities. Variable depth control allows practitioners to combine both deep and superficial treatment approaches depending on the area being treated, the skin type or the indication. Variable depths can also be used for combination work on the same area to achieve optimal results. -2-1 0 +1 +2

THE Q-SWITCHED LASER ADVANTAGE Long Pulsed Nd:YAG Laser (LP) Maximizing the potential of the 1064nm wavelength, ALMA-Q also offers the Long-Pulsed Nd:YAG laser for the treatment of vascular lesions, malformations and deep veins. The extended duration of the long-pulsed 1064nm laser affords deep penetration and powerful heating, facilitating treatment of deeper lesions that cannot be targeted by shorter wavelengths. Quasi-Long Pulsed Nd:YAG Laser (QLP) The Quasi-Long Pulsed Nd:YAG laser generates submillisecond pulse widths at a high repetition rate of 5Hz to provide both skin rejuvenation and microvascular treatments. The QLP laser achieves safe and effective sub-dermal heating, stimulating the growth of new collagen and tightening skin laxity. At the same time, its ultra-short pulse duration makes it ideal for treating microscopic blood vessels with diameters of less than 50 microns. d (µm) 300 250 200 150 100 50 0 0 1 2 3 4 Pulse Duration t o (ms) 5 6 7 8 9 10 Listen to our experts: I have been using all kinds of laser technologies in my private clinics for more than 20 years now. Having that said, I can safely say that ALMA-Q is one of the most effecient platforms I have worked with. The use of different pulse durations; nanoseconds, microseconds and miliseconds enabled me to use it for the same indication with different combinations. It is powerful for tattoo and pigment removal treatments, and I like the depth controlled-non-ablative fractional capabilities. In my opinion, every patient that walks into a dermatology clinic from early ages to later years is a candidate for a treatment with ALMA-Q. Dr. Şerafettin Saraçoğlu, MD, Dermatology Specialist, Clinic Estesense Nisantasi, Istanbul Elit Policlinic, Bakirkoy, Istanbul

HANDPIECES Offers 7 distinct spot sizes: from 1 to 7mm, to address various degrees and depths of pigmented lesions and varying types of tattoos. The handpiece may be used in either Q-Switched, Long Pulsed or Quasi-Long Pulsed Nd:YAG laser modes. HomoGenius Treats pigmented lesions and tattoos using a homogenized laser beam profile with uniform energy intensity, preventing hot spots. A square beam with 3x3 mm2 or 5x5 mm2 spot sizes allow for coverage of treatment areas without overlap. The Homogenizer handpiece may be used in Q-Switched laser mode. HomoGenius Laser Beam Profile Fractional (With depth control) Employs a fractional delivery method which creates pixel-sized perforations in a 7x7 nonablative pattern, leaving the surrounding tissue intact. These micro-injury sites trigger a wound healing 7x7 Pixel Array process that strengthens collagen and stimulates neo collagenesis, completely rejuvenating the target tissue. Five distinct treatment depths are available for maximum flexibility and precision. Collimated The collimated handpiece delivers parallel beams of energy to the target tissue with minimal dispersion, regardless of distance from the skin. This allows practitioners to administer treatment without having to maintain continuous contact with the skin while also allowing better visualization of larger treatment areas. With an 8mm spot size, this handpiece offers an excellent coverage rate and high speed treatment. The Collimated handpiece may be used in either Q-Switched, Long Pulsed or Quasi-Long Pulsed Nd:YAG laser modes. Spectrum-Y & Spectrum-R The Spectrum handpieces extend the capabilities of ALMA-Q s Q-switched laser, offering two additional wavelengths with precise ink targeting for especially challenging tattoo colors. The Spectrum-Y handpiece (585nm) specifically treats sky blue and the Spectrum-R (650nm) treats green and teal.

INDICATIONS Pigmented Lesions ALMA-Q is highly effective for treating various degrees and depths of pigmented lesions as well as melasma. The high power Q-switched Nd:YAG 1064nm laser treats deep pigmented lesions, while the monochromatic 532nm wavelength addresses superficial pigmented lesions. The treatment mechanically breaks up the melanin in the lesions without causing thermal damage, revealing lighter, unblemished skin. BEFORE AFTER Courtesy of: Clinical Department, Alma Lasers Ltd. Skin Remodeling ALMA-Q features the first fractional non-ablative Q-switched laser that offers depth control, allowing practitioners to use the powerful benefits of a high intensity Q-switched laser for the treatment of age-related skin imperfections including wrinkles, fine lines, photodamage, uneven skin tone and skin laxity. These indications may also be addressed using the Quasi- Long Pulsed Nd:YAG 1064nm laser which achieves neocollagenesis and skin remodeling through selective heating. BEFORE AFTER Courtesy of: Clinical Department, Alma Lasers Ltd. The QLP emits light through ultra-short pulses at a high repetition rate to elevate dermal temperature. This mechanism causes micro thermal injury to the tissue which contracts existing fibers, stimulates the formation of new collagen (especially collagen type III) and improves its alignment and thickness. Both treatments are safe and effective for even thin and delicate areas of the skin such as the face, neck and décolleté areas. Vascular Lesions The Long-Pulsed Nd:YAG 1064nm laser provides a powerful, non-invasive solution for vascular lesions, malformations and deep veins. In addition to its deep penetration and effective heating, the 1064nm wavelength is more readily absorbed by water and oxy-hemoglobin with relatively low absorption by melanin. This triggers photothermolysis of the water and hemoglobin chromophore, effectively targeting vascular lesions while avoiding damage to the epidermis. BEFORE AFTER Courtesy of: Clinical Department, Alma Lasers Ltd. The ultra-short pulse duration of the Quasi-Long Pulsed Nd:YAG 1064nm laser makes this mode ideally suited for treating microvasculature (<-50μm in diameter), including angioectasias, telangiectasias and erythema in melasma lesions.

Tattoo Removal Successful multi-color tattoo removal requires a high powered laser that can deliver enough energy within the absorption spectrum of a wide range of colors. Alma-Q offers four distinct Q-switched Nd:YAG laser wavelengths, each targeting a specific ink color for full-spectrum multi-color tattoo removal. The high power QSW 1064nm laser is ideal for treating darker ink colors, while the 532nm wavelength is effective for brighter ink colors, including red, orange and yellow. The 585nm wavelength specifically targets sky blue and the 650nm wavelength targets green and teal. BEFORE AFTER 3 RD TREATMENT ALMA-Q mechanically breaks down the ink particles in the tattoo without causing thermal damage, revealing healthy, color-free skin with minimal risk of scarring or permanent hypopigmentation. 532 nm 585 nm 650 nm 1064 nm BENEFITS Combined Q-switched, Long Pulse and Quasi-LP Nd:YAG laser platform - offering maximum versatility Multiple Wavelengths - for full spectrum multi-color tattoo removal Double Pulse Technology - delivering maximum power Unique Depth Control Capabilities - for precise and accurate treatment Fractional Delivery - addressing a wide range of indications Safe & Effective - for all skin types (I-VI) as well as for thin and delicate areas

ALMA-Q SPECIFICATIONS Operation Mode Wavelength Handpiece Spot Size Pulse Duration Repetition Rate Maximum Pulse Energy QS 1064 1064nm Collimation 1-7mm 8mm 7ns Up to 10Hz Single pulse: 1200mJ Double pulse: 2000mJ Fractional 7x7 spots 11x11mm Single pulse: 20mJ/pixel Double pulse: 34mJ/pixel QS 1064 1064nm HomoGenius 3x3mm 5x5 mm 7ns Up to 10Hz Single pulse 1050 mj Double pulse 1800mj QS 532 532nm Collimation 1-7mm 8mm 7ns Up to 10Hz Single pulse: 450mJ Double pulse: 700mJ QS 585 585nm Spectrum-Y 2mm 7ns Up to 2Hz QS 650 650nm Spectrum-R 2mm 7ns 1Hz Single pulse: 270mJ Double pulse: 450mJ Single pulse: 220mJ Double pulse: 330mJ LP 1064 1064nm Collimation 1-7mm 8mm 10-60ms 1-3Hz 30J QLP 1064 1064nm Collimation 1-7mm 8mm 400μsec Up to 5Hz 4J Alma Lasers GmbH Nordostpark 100-102, 90411 Nuremberg, Germany Tel. + 49 911 / 89 11 29-0 Fax + 49 911 / 89 11 29-99 Email: info@almalasers.com www.almalasers.com PBAP24011606_02 2017 Alma Lasers. All rights reserved Alma Lasers, its logo, and Alma-Q are trademarks or registered trademarks of Alma Lasers. In the United States and/or other countries. Product specifications are subject to change without notice. CONNECT WITH ALMA LASERS