Specific skin care for companion animals recommended by veterinarians

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www.dermoscent.com Specific skin care for companion animals recommended by veterinarians LABORATOIRE DE DERMO-COSMETIQUE ANIMALE Technopôle Castres/Mazamet - ZA Le Causse - 81100 Castres France

LDCA Laboratoire de Dermo-Cosmétique Animale A dermo-care specialist dedicated to companion animals Thanks to the know-how and experience acquired in French human dermo-cosmetic industry by its founders, LDCA has conceived and developed Dermoscent. Conceived by veterinarians for veterinarians, all Dermoscent products are commercialized through vet clinics or selective pet stores where competent and appropriate veterinary advice is available. Developed by an R&D staff composed of both veterinarians and pharmacists specialized in dermo-cosmetics, each formulation of Dermoscent products is based on 10 natural ingredients, rigorously selected to improve and enhance your companion animals skin health and hair beauty. Through a practical skin care regimen with easy and rapid application, Dermoscent enables remarkable results in improving animals health and well-being thanks to a regular and frequent use. The first animal dermo-cosmetic brand in the world dedicated to animal skin health, well-being and hair beauty A successful alliance between nature and science for your companion animal Upon regular and frequent use of Dermoscent products, the skin of your companion animal is hydrated and nourished; hair becomes stronger, shinier and smoother. Without any added fragrance nor paraben, Dermoscent products balance skin ecosystem, help controling excessive hair-loss & scaling and improve animal s smell to make it more adapted to its human environment. The efficacy of Dermoscent treatment contributes to the physical and psychological well-being of the animal which in turn contributes to an obvious improvement in the quality of moments shared between compagnion animals and their owners. Dermoscent product advantages are multiple: simple and easy to use, proven efficacy, formula safety with an optimal tolerance, natural and organic ingredients to preserve the environment. Dermoscent is particularly recommended for dogs and cats as an efficient moisturising care to repair and reinforce the skin barrier function. Dermoscent products are also often used as an adjunctive care by veterinarians to complement other treatments against all kinds of skin disorders and diseases linked to impaired skin barrier function. For any dermatological pathology, please consult your veterinarian for a precise diagnostic. 2 3

- Multifunctional Care p 7 - Hygienic Care p 9 - Specific Care p 15 Spot-on Shampoo EFA Shampoo MOUSSE BIO BALM ATOP 7 Paraben-free and no added fragrance All Dermoscent products are tested by veterinarians to ensure an optimal tolerance and an irreproachable product quality for your companion animal. 5

Spot-on Skin care for dogs & for cats Active Ingredients Essential oils (rosemary, lavender, melaleuca, cedar, oregano, mint, camphor, etc.), essential fatty acids of omega 3 & 6 extracted from grain oils of hemp and neem, soothing and purifying agents, Vitamin E. Preservative-free Complete multifunctional care for all skin and coat types Patented, hypoallergenic without added fragrance, Essential 6 spot-on is formulated with 10 natural ingredients. Its exceptional formulation with clinically proven efficacy is based upon a rigorous selection of ingredients for their efficacy, purity and synergistic properties. Essential 6 spot-on - Maintains and restores the integrity of the hydrolipidic film, - Favours cutaneous ecosystem balance, - Purifies and helps preventing skin irritations due to skin dehydration, - Deodorises by respecting animal s own smell, - Helps diminishing non seasonal hair loss and sustaining hair growth, - Protects by its antioxidant effect to combat free radicals. Break the snap-off top along the scored line. Part the coat between the shoulders or on the neck until skin is visible. Empty its contents onto the skin at one or 2 spots. No massage is required. Thanks to its bio-diffusing agent, Essential 6 spot-on automatically diffuses over animal s body. Avoid bathing 2 days before and 2 days after the application. For an optimal result, it is highly recommended to start an initial treatment of 2 consecutive months by applying one pipette every week followed by a regular use of one pipette every 2 weeks as long as possible. Essential 6 spot-on has been tested by veterinarians to ensure an optimal tolerance and an irreproachable product quality for your animal. Products are specifically dosed according to animal weight. Usage tips: -During rainy season to ensure a pleasant odour after a promenade. -During warm period while your companion animal stays often outdoors and gets exposed more easily to sun or other environmental aggressions. Spot-on Essential 6 spot-on hydrates and balances its epidermis by offering an anti-oxidant and anti-free radical protection. -A regular brushing is always recommended to eliminate dead hair and encourage hair growth. Clinical trials undertaken by veterinarians The product efficacy has been proven through a multicentric study realized in several vet clinics in different countries under veterinarian control and monitoring. Remarkable and rapid improvements have been demonstrated on 195 dogs and 73 cats treated during one month with Essential 6 spot-on. Based on a scoring method, product performance was evaluated before and after the treatment on several criteria: hair shine, hair loss, scaling, deodorising and skin balance. 10 9 7 6 5 4 3 1 9 7 6 5 4 3 1 from D0 to D28 Shine 185 dogs Anti-Hairloss 164 dogs Anti-Dandruff 157 dogs Odour 183 dogs Balance 170 dogs from D0 to D28 Shine 71 cats Anti-Hairloss 69 cats Anti-Dandruff 61 cats Hair Balance 58 cats 7

Shampoo for dogs & for cats Active Ingredients Essential oils (rosemary, lavender, melaleuca, cedar, oregano, mint, camphor, etc.), essential fatty acids of omega 3 & 6 extracted from grain oils of hemp and neem, saponaria root, lichen extract, soothing and purifying agents, nourishing agent, Vitamin E. Complementary to Physiological shampoo Frequent use for all skin and coat types not only cleanses but also soothes, deodorizes and hydrates. Formulated with a 10 biodegradable cleansing base, mild and efficient, made of lipo-amino acids of green apples and saponaria root, offers a total s. - Cleanses mildly yet thoroughly, adapted for all skin and hair types, - Eliminates dirt, scales and bad odour, - Hydrates and balances skin hydrolipidic film. shampoo for frequent use without any risk of damaging the skin or hair. Wet the animal and spread the product over animal's body. Massage slightly to develop a good volume of foam. Thanks to its ecological cleansing base, the foam is normally. Shampoo Clinical trials undertaken by veterinarians The product efficacy has been proven by a clinical study realised on 8 dogs and 5 cats under veterinarian control and monitoring. Remarkable results on several criteria have been demonstrated. 1 10 6 4 1 10 6 4 Shine Shine Deodorant Anti- Anti- Balance Balance 9

EFA EFA shampoo for dogs & for cats Shampoo Suitable for sensitive skins with allergic reactions First animal shampoo based on 10 natural ingredients agent, EFA Treatment Shampoo Apply Shampoo other dermatological treatments. Wet the animal and spread the product over animal's body. Massage slightly to develop a good volume of foam. Thanks to its ecological cleansing the animal normally. Active ingredients Essential fatty acids of omega 3 & 6 extracted from grain oil of hemp, green apple lipo-amino acids, niaouli essentail oil, Cucurbitine, saponaria root, lichen extract, natural nourishing and hydrating agents. CUCURBITINE 6 day Treatment HISTAMINE in mast cellgranules SOOTHING EFFECT EFA Treatment Shampoo - Clea Stress (physical & chemical) Epidermis Dermis Hypodermis Mastocyte - Reduces scaling, - Hydrates and reinforces natural epidermal defence. As all the other cleansing products of Dermoscent, EFA Treatment Shampoo is formulated with a 10 biodegradable cleansing base, mild and efficient, made of lipo-amino acids of green apples and saponaria root, which respect. Clinical trials undertaken by veterinarians The product efficacy has been proven by a clinical study realised on 8 dogs and 6 cats under veterinarian control and monitoring. Remarkable results on several criteria have been demonstrated. 1 10 6 4 1 10 6 4 Irritation Shine Deodorant Irritation Shine 11

Foam for dogs & for cats GAS FREE WITH ECO-REFILL Rinse-free repairing cleaner For frequent use Usage Tips: -Essen al Mousse is the ideal repairing cleanser for Contained in an environment friendly gas free pump bo le, Essen al Mousse is the rst rinse-free & soap-free repairing cleanser for dogs and for cats. Containing also Cucurbi ne, the same revolu onary soothing agent as EFA Treatment Shampoo, Essen al Mousse calms cutaneous irrita ons while cleanses. Based on a 10 biodegradable formula on with a mild and efficient cleansing base made of lipo-aminoacids of green apples and saponaria root, Essen al Mousse cleanses and moisturizes by offering an op mal skin tolerance and a total ecological respect. companion animals living in rela vely small residence like city ats. -For indoor companion animals, Essen al Mousse enables a localised cleansing within seconds a er each promenade (ex. paws). -Essen al Mousse enables an easy cleansing on turbulent, wounded, aged or water-resistant companion animals. It is ideal for animals in convalescence (ex. post-surgery). Essen al Mousse Clinical trial undertaken by veterinarians - Eliminates dirt without rinse, - Deodorises bad odours, - Soothes and diminishes skin irrita ons, - Hydrates the hydrolipidic lm, - Reinforces the natural defence of epidermis. The product efficacy has been proven by a clinical study realised on 8 dogs and 7 cats under veterinarian control and monitoring. Remarkable results on several criteria have been demonstrated. Ac ve Ingredients Essen al fa y acids of omega 3 & 6 extracted from grain oil of hemp, essen al oil of niaouli, Cucurbi ne, lipo-amino acids of green apple, saponaria root, lichen extract, natural detangling and so ening agents. SE MOUS Shake before use. Put foam in one hand and apply directly with hands onto animal hair or with the help of a brush. Spread evenly the foam and make gently penetrate the foam into the mass of hair. Apply the foam onto the whole body or areas requiring for cleansing by avoiding eyes and muzzle. Wrap the animal with a dry towel and rub to remove dirt and over-applied product. Let dry naturally and brush the hair. Your companion animal would appreciate par cularly Essen al Mousse for a pleasant massage and caressing moment. This soap-free and rinse-free repairing cleanser is recommended for frequent use. 10 9 7 6 5 4 3 1 10 9 7 6 5 4 3 1 Shine Deodorant Easy to use Shine Easy to use 13

BIO BALM Balm for dogs Repairing and protective care For paws, muzzle and callus biotechnology to take care of dog s paws, muzzle and callus. agents, this 10 eco-friendly formula gives an immediate superficial wounds. lesions, BIO BALM nourishes and repairs the barrier wound healing. Apply BIO BALM on dry and cleansed paws or other is recommended to apply BIO BALM hyperkeratosis or superficial wounds. BIO BALM is Tested by veterinarians during one of the most challenging sled dog races in the world, La Grande Odyssée held in French and Swiss Alps in 2008, BIO BALM has been proven with a remarkable performance on more than 300 BIO BALM the painful feeling. Thanks to its formula efficacy with a waterproof texture, only a small amount of product is BIO BALM - Repairs and protects the paws of your dogs before and - Prevents and treats callus and hyperkeratosis of muzzle, - Offers an immediate soothing effect to relieve pain and irreproachable product quality. Clinical trials undertaken by veterinarians The product efficacy has been proven by a study realised on 60 dogs under veterinarian control and monitoring. Remarkable results on several criteria have been demonstrated. 1 10 6 4 Active ingredients Essential oil of Cajputi, palm and soya oils, natural soothing and healing agents. Preservative-free and 93% organic certified formula Easy to use Hydrating Helps healing Reduces congestion Soothing Stops irritation Repairing & protective 15

Active ingredients Essential fatty acids of omega 3 & 6 extracted from grain oils of hemp and neem, essential oil of cajeputi and melaleuca, caper flower bud extract, natural soothing agents. Spray for dogs A frequent use treatment formulated with 10 natural active ingredients, it soothes damaged epidermis, repairs skin barrier function and balances skin ecosystem. Itchy skin? The skin plays a key role in protecting animal from dehydration due to all kinds of environmental aggressions. This protection being ensured partially by the hydrolipidic film which is composed of water and sebum, the skin is nevertheless exposed to various physical aggressions such as cold temperature, wind, sun, pollution, or chemical aggressions such as non adapted skin care or harsh topical medications, or bacterial aggressions. A damaged hydrolipidic film can no more protect the skin and leaves the animal with an over sensitive skin showing redness, tightness, dryness, itchiness and other forms of discomfort. The answer ATOP 7 Soothing emulsion For itchy or allergy-prone skins It reinforces hydrolipidc film by diminishing cutaneous hypersensitivity and dehydration of irritated or allergy-prone skins. It soothes, protects and moisturizes. Moisturize-loss decrease Essential Fatty Acids benefits Hydrolipidic Film Regeneration 2 ND skin effect - long lasting protection In- depth penetration SUBMICRONIC EMULSION Inhibitory Action Hypersensitivity Reaction Epidermis scheme Hydrolipidic Film Epidermic cell Liberation of Hypersensitivity Molecules ATOP 7 Its submicronic emulsion (microparticules sized between 0.1 to 0.4 μm) allows an instant penetration and action. Its 2nd skin resulting from the constitution of an invisible and non-occlusive patch ensures a long-lasting effect of several hours. ATOP 7 is a steroid-free soothing care for frequent use with an optimal cutaneous tolerance. ATOP 7 - Soothes cutaneous hypersensitivity of irritated or allergy-prone skins thanks to a natural soothing agent, caper flower bud extract, - Purifies the skin thanks to Melaleuca and Cajeput essential oils, - Restores hydrolipidic film thanks to essential fatty acids of omega 6 & 3. Spray directly onto areas to be treated, once or several times a day according to skin irritation of your animal with a maximum of formula safety for frequent use. Clinical trials undertaken by veterinarians The product efficacy has been proven by a clinical study realised under veterinarian control and monitoring with a scoring method on 10 dogs suffering from various degrees of pruritic dermatitis. All dogs were treated during one month with ATOP 7 spray. Remarkable results have been demonstrated on criteria of lesion surface, lesion intensity, erythema and itchiness. Lesion Surface Lesion Intensity Erythema SPRAY Itching 1 3 4 5 6 7 17

CUSTOMER SATISFACTION QUESTIONNAIRE Let us know about the results of your use of one of our products. Your response would help us tremendously to Date: Country: Name of owner: Email (or telephone number): Your pet: Dog Cat Breed: Name of animal: Age of animal: Product used: EFA Treatment Shampoo for dogs/or for cats BIO BALM for dogs ATOP 7 for dogs Optimal hydration to sustain the skin barrier function Result appraisal: - Hair aspect: Shinner Unchanged - Hair loss (non seasonal loss): Improved Unchanged - Dandruff: Improved Unchanged - Odour: Improved Unchanged - Skin balance: Less greasy Less dry Unchanged Improved Unchanged Service appraisal: How did you know about Dermoscent products? From your veterinarian From your pharmacist Other: please precise: If you bought the product directly in a veterinary clinic: yes no If you ordered the product from a website: Dermoscent website (www.dermoscent.com) Another website, please precise the site: www.. yes no yes no Other comments: