Programme BREGENZ SUMMER SCHOOL ON ENDOCRINOLOGY: Main Topics

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EnForCé DFG KFO M A I N T A I N K F O 2 1 8 / 0 Programme BREGENZ SUMMER SCHOOL ON ENDOCRINOLOGY: Main Topics THE HPG AXIS AND THE OVARY DEVELOPMENT AND DIFFERENTIATION OF MESENCHYMAL STEM AND PROGENITOR CELLS AND ENDOCRINE CELLS HORMONES, AGING AND DISEASES Sunday, July 18 th - Thursday, July 22 nd, 2010 Monastery Mehrerau Bregenz, Austria Sponsored by the DFG-funded Graduate Colleges 1041 & 1208 and the DFG KFO 218. This is a joint project with the German Society of Endocrinology (DGE) and the DGE Young Active Research (YAR), the European Society of Endocrinology (ESE), and the Deutsche Gesellschaft für Osteologie (DGO). The German Society of Endocrinology and DFG funded projects can sponsor travel grants for young graduates and postgraduates.. Venue: Monastery Mehrerau Mehrerauerstr. 68 6903 Bregenz, Austria Tel.: +43 5574 714 38 Fax: +43 5574 714 94 E-mail: direction@mehrerau.at Web: http://www.mehrerau.at Scientific Organizing Committee: Josef Köhrle (Charité, Berlin) Franz Jakob (University of Würzburg), Jochen Seufert (University of Freiburg), Clara Alvarez (ESE), Bernhard Otto Böhm (University of Ulm) and Representatives of YAR Group 2010: Mona Mischke, Berlin; Frank Möller, Dresden; Mette Stoedter, Berlin Scientific Conference Office: Conference Registration: Institute of Experimental Endocrinology Charité University Medicine Berlin Mrs. Elke Abdel-Karim Augustenburger Platz 1 D-10117 Berlin, Germany Tel.: + 49 30 450 524022 E-mail: elke.abdel-karim@charite.de Endoscience Endokrinologie Service GmbH Mozartstrasse 23 D-93128 Regenstauf Tel. +49 (9402)-94811-10 E-Mail: info@endoscience.de Organizer/Veranstalter: Akademie für Fort- und Weiterbildung der DGE https://www.event-endoscience.de/tms/frontend/frontend.cfm?l=3063&id=0&dat_h=&sp_id=2&modus=

CONFERENCE PROGRAM SUNDAY, 18 JULY 2010 15:30 AND INTRODUCTION OF PARTICIPANTS Participants will introduce themselves, their interest and field of work. Startup Session: 17:00 Stem cell development and nuclear receptors Barbara Demeneix, Paris, France 19:00 Dinner (Restaurant Klosterkeller) MONDAY, 19 JULY 2010 Morning Session 1: Models in Endocrinology Young Investigator s Day Sports & Lectures Coordination: Mona Mischke (Berlin), Frank Möller (Dresden), Mette Stoedter (Berlin) 08:30 Warm up and getting to know each other with joint sports activities (Volleyball, Badminton, Handball, Soccer, Swimming) 10:00 Making β cells Francesca Spagnoli, Berlin, Germany 10:50 Corpora lutea function, ovulation and pregnancy in "Vizcachas (Lagostomus maximus), a south-american endocrine model organism Federico Jensen, Magdeburg, Germany 11:40 Abuse of anabolic steroid prohormones in cattle breeding Jeroen Rijk, Wageningen, NL 12:30 Lunch Sports and Fun 15:00 Parallel Session 1: Interactive Courses (will be repeated) A1 Induced pluripotent stem cells Tobias Cantz, Hannover, Germany

15:00 Parallel Session 1: Interactive Courses, cont. (will be repeated) B1 The bone/vascular interface common mechanisms of osteoporosis and vascular calcification Lorenz Hofbauer, Dresden, Germany C1 Thyrocyte function Josef Köhrle, Berlin, Germany 15:50 mirna, β-cells and diabetes Markus Stoffel, Zürich, Switzerland 16:40 Adrenocortical development Gary D. Hammer, Ann Arbour, USA Afternoon Session 1: DEVELOPMENT AND FUNCTION OF ENDOCRINE CELLS 17:30 Parallel Session 2: Interactive Courses (will be repeated) D1 β-cell transcription factors and signalling Jochen Seufert, Freiburg, Germany E1 Current trends in PCOS research Evanthia Diamanti-Karantides, Athens, Greece 18:30 Light F1 Bone Dinner cell development Paolo Bianco, Roma, Italy 18:30 Light Dinner 19.30 After Dinner Lecture 1 Pathogenesis of postmenopausal osteoporosis update 2010 Lorenz Hofbauer, Dresden 20:30 Poster Session 1: Introduction and short presentations in front of posters TUESDAY, 20 JULY 2010 Morning Session 2: THE HPG AXIS AND THE OVARY 08:30 Neurokinin signalling and puberty Kemal Topuloglu, Adana, Turkey 09:20 Does puberty begin with a kiss? Kisspeptin Jens D. Mikkelsen, Copenhagen, Denmark 10:10 Coffee Break

10:40 Ovarian reprogramming (FOXL2) N. Henriette Uhlenhaut, Heidelberg, Germany 11:30 Parallel Session 3: Interactive Courses B2 The bone/vascular interface common mechanisms of osteoporosis and vascular calcification Lorenz Hofbauer, Dresden, Germany D2 β-cell transcription factors and signalling Jochen Seufert, Freiburg, Germany E2 Current trends in PCOS research Evanthia Diamanti-Karantides, Athens, Greece 12.30 Lunch Sports and Fun 15:15 Parallel Session 4: Interactive Courses A2 Induced pluripotent stem cells Tobias Cantz, Hannover, Germany C2 Thyrocyte function Josef Köhrle, Berlin, Germany F2 Bone cell differentiation and plasticity Franz Jakob, Würzburg, Germany Coffee Afternoon Session 2: Ovary and Ageing 16:10 AMH and the ovarian reserve Jenny A. Visser, Rotterdam. Netherlands 17:00 PCOS in Adolescents Evanthia Diamanti-Karantides, Athens, Greece 18:00 Light Dinner 19:00 After Dinner Lecture 2: Cell biology of a stem cell Paolo Bianco, Roma, Italy 20:30 Poster Session 2: Introduction and short presentations in front of posters

WEDNESDAY, 21 JULY 2010 08:15 Joint sports activities (Volleyball, Badminton, Handball, Soccer, Swimming) Morning Session 3: Novel Trends in Hormones & Aging Research 09:30 FGF23 & Vitamin D receptor Beate Lanske, Boston, USA 10:20 Coffee Break 10:50 mirnas and aging mesenchymal stromal cells Günter Lepperdinger, Innsbruck, Austria 11:40 Parallel Session 5: Interactive Courses (will be repeated) G1 Perspectives of Postdocs: Research and Funding Programs Patricia Fuchs, KoWi, Bonn, Germany H1 Genes and Pathways Thomas Illig, Munich, Germany I1 International Scholarships NN DAAD 12:30 Lunch Sports and Fun 15:00 Parallel Session 6: Interactive Courses J1 Phytoestrogen and steroid hormone action Oliver Zierau, Dresden, Germany G2 Perspectives of Postdocs: Research and Funding Programs Patricia Fuchs, KoWi, Bonn, Germany H2 Genes and Pathways Thomas Illig, Munich, Germany Coffee Afternoon Session 3: New Trends in Hormone and Metabolic Research 15:50 Genetic Variation in Human Metabolism Thomas Illig, Munich, Germany 16:40 The difference of (brown) fat cells Alexandros Vegiopoulos, Heidelberg, Germany 17:30 Brite adipose tissue, obesity and thermogenesis Natasa Petrovic, Stockholm, Sweden

18.30 Light Dinner 20:00 Poster Session 3: Introduction and short presentations in front of posters THURSDAY, 22 JULY 2010 8:30 12:30 Young Investigator s Session 2 Coordination: Mona Mischke (Berlin), Frank Möller (Dresden), Mette Stoedter (Berlin) 08:30 Morning Sports 10:00 A life scientist in criminal and forensic diagnostics Harald Brumm, Berlin, Germany 10:45 General Discussion and evaluation of the topics and format of this year s Summer School 11:45 Feedback and discussion with the organizers, proposals and suggestions for 2010 12:15 Farewell 12.30 Lunch

GENERAL INFORMATION The Bregenz Summer School has a long standing tradition as an interactive hormone and endocrine related brain-storming and meeting place between academia, industry and clinicians. The meeting venue is in a newly renovated complex of beautiful old buildings of the Collegium Bernardi, a boarding school operated by Kloster Mehrerau, within easy walking distance to the shore of the Lake Constance, Bregenz City Park, and a nature preserve. Bregenz, the State Capital of Vorarlberg, is a modern city of 27,000 and is the cultural center of the province. The Collegium Bernardi can house up to 120 guests, participation will be confirmed on first come - first served basis. Please note that the Summer School is being held during the Bregenz Opera Festival therefore alternative accommodations may be difficult to obtain. Deadline for registration is July 9 th! PARTICIPATION FEES Registration Acc.& board 4 days Senior Scientists 200.00 + 240.00 = 440.00 Students/Postdocs (including accommodation) 100.00 + 180.00 = 280.00 Registration fee for students, postdocs and other participants is including entry to all sessions, welcome reception on Sunday afternoon, coffee breaks and the conference handout. The room and full board package for the entire meeting is 240.00 EUR for senior scientists and 180.00 EUR for students and postdocs. In case of accommodation outside the monastery, meals and coffee breaks at the monastery must be paid cash on site. For Students/Postdocs only: Depending on attracted sponsorship, the registration fee can be refunded upon active participation which requires a poster presentation. Students who will be presenting a poster may apply for reimbursement of the registration fee. In addition, a limited number of travel grants will be available for graduate students/postdocs, depending on incoming support from sponsoring companies/organizations. If only limited money is available, poster-presenting students/postdocs will be preferred. Money refunding and participation will be made available on a first register and pay, first served basis. Online registration: http://www.endoscience.de/ Payment Registration will be confirmed by mail. If no confirmation is received within one week, please contact the Congress secretariat. Cancellation and refund policy Notification of cancellation must be made in writing and mailed to the congress secretariat with a reference to the bank account where a possible refund may be remitted to. An administrative fee of 30 will be charged for refunds. Cancellation and refund fee Before June 30, 2010, total refund (excluding the administrative fee). After June 30, 2010 no refunds should be expected. Credit will not be given for unattended events, late arrivals or early departure. All refunds will only be processed after the Congress. The Bregenz Opera Festival will be presenting Giuseppe Verdi's "AIDA" on the floating stage. There are still a few tickets available for the premiere (2 nd year) on Thursday July 22, 9:15 PM (to be booked directly by internet 28, 48, 70, 90 EUR). In case demand exceeds the supply, you may purchase your tickets, as well as for the

House Premiere on July 21 Die Passagierin (M.Weinberg) via internet (http://www.bregenzerfestspiele.com/ or telephone: +43 5574 407-6 (ticket center). The beautiful landscape of Bregenz and its surroundings invites for a variety of sports and recreation - swimming, soccer, tennis, skating all around the lake - please don t forget to bring along your sportswear! ALL SPEAKERS PLEASE NOTE: This summer school is not in the format of a scientific research meeting, but has a strong educatory character and aims to encourage young investigators to get integrated into the scientific community and to build their networks. The speakers and the meeting will be evaluated by the participants. Please leave at least 15 minutes of your allocated time slot for discussion and questions, organize your presentation as interactive as possible, and please give all attendees their chance to get most out your presentation by providing a general and specific introduction into your field of research. Please prepare a short handout, 1-2 pages, including your short CV, summarizing the most important messages of your presentation, the model and methods employed, some key slides and the take-home messages. Deadline for your e-mail submission to the Conference Office: elke.abdelkarim@charite.de is July 5 th. For the layout of your slides presentation as well as for your handout please use dark text on light backgrounds. ALL STUDENTS PLEASE NOTE: Get the most out of the invited speakers, be prepared for the session, and get your questions and comments ready for the speakers. ------------------------------------------------------------------------ Sponsors & Support Deutsche Gesellschaft für Endokrinologie (DGE) EnForCé DFG Graduiertenkollegs 1041 Uni Ulm & 1208 Charité ----------------------------------------------------------------------- Travel information The most convenient airport is Zurich, Switzerland. Alternatives are Friedrichshafen or the regional airport St. Gallen Altenrhein (via Vienna). For train connections from the airports please turn to: http://www.sbb.ch/en/, http://www.bahn.de/, http://fahrplan.oebb.at/ At Bregenz train station you might take the city bus (green line, 1 ), departing every 30 minutes. A walk from the train station to the monastery takes about 15-20 minutes. footpath/bikepath between railway opera monastery bus route / street between railway station - monastery