Material Safety Data Sheet NFPA HMIS Personal Protective Equipment 0 Health Hazard Fire Hazard 0 See Section 5. Section. Chemical Product and Company Identification Common Name/ Trade Name a-amylase Catalog Number(s). CAS# A874 Page Number: 903-0-8 or 9000-90-2 or 900-9-8 Manufacturer Commercial Name(s) Synonym Chemical Name SPECTRUM LABORATORY PRODUCTS INC. 4422 S. SAN PEDRO STREET GARDENA, CA 90248 Fungal Amylase (from Aspergillus oryzae); Amylase, alpha-, Aspergillus oryzae; alpha-amylase; alpha-amylase 200 U/mg,4-alpha-D-glucan glucanohydrolase RTECS TSCA CI# BU7432500 for CAS no. 9000-90-2 T SCA 8 (b ) i n ve n t o ry: a-amylase IN CASE OF EMERGENCY CHEMTREC (24hr) 800-424-9300 Chemical Family Chemical Formula Supplier SPECTRUM LABORATORY PRODUCTS INC. 4422 S. SAN PEDRO STREET GARDENA, CA 90248 CALL (30) 56-8000 Section 2.Composition and Information on Ingredients Name CAS # Exposure Limits TWA (mg/m 3 ) STEL (mg/m 3 ) CEIL (mg/m 3 ) % by Weight ) {a-}amylase 903-0-8 or 9000-90-2 or 900-9-8 00 Toxicological Data on Ingredients a-amylase : ORAL (LD50): Acute: >7500 mg/kg [Rat [information from RTECS]]. >5000 mg/kg [Mouse]. >2000 mg/kg [Rat [information from vendor]].
a-amylase Page Number: 2 Section 3. Hazards Identification Potential Acute Health Effects Potential Chronic Health Effects Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Slightly hazardous in case of skin contact (irritant). CARCINOGENIC EFFECTS: MUTAGENIC EFFECTS: TERATOGENIC EFFECTS: DEVELOPMENTAL TOXICITY: Section 4. First Aid Measures Eye Contact Skin Contact Serious Skin Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 5 minutes. Cold water may be used. Get medical attention if irritation occurs. Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used. Inhalation Serious Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Ingestion Serious Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Section 5. Fire and Explosion Data Flammability of the Product Auto-Ignition Temperature Flash Points Flammable Limits Products of Combustion Fire Hazards in Presence of Various Substances Explosion Hazards in Presence of Various Substances Fire Fighting Media and Instructions Fire Hazards Explosion Hazards May be combustible at high temperature. Slightly flammable to flammable in presence of heat. Non-flammable in presence of shocks. Slightly explosive in presence of open flames and sparks. Non-explosive in presence of shocks. SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. As with most organic solids, fire is possible at elevated temperatures Fine dust dispersed in air in sufficient concentrations, and in the presences of an ignition source is a potential dust explosion hazard.
a-amylase Page Number: 3 Section 6. Accidental Release Measures Small Spill Large Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Section 7. Handling and Storage Precautions Storage Keep away from heat. Keep away from sources of ignition. Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above -20 C (-4 F). Deep Freeze. Section 8. Exposure Controls/Personal Protection Engineering Controls Personal Protection Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of a Large Spill Exposure Limits Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Section 9. Physical and Chemical Properties Physical state and appearance Molecular Weight ph (% soln/water) Solid. (Powdered solid.) Odor Taste Color Characteristic. Off-white. Brown. Tan. Beige. Boiling Point Melting Point Critical Temperature Specific Gravity Vapor Pressure Not applicable. Vapor Density Volatility Odor Threshold Water/Oil Dist. Coeff. Ionicity (in Water) Dispersion Properties Solubility
a-amylase Page Number: 4 Section 0. Stability and Data Stability Instability Temperature Conditions of Instability Incompatibility with various substances Corrosivity The product is stable. Excess heat, dust generation, incompatible materials Reactive with oxidizing agents. Corrosivity Polymerization Will not occur. Section. Toxicological Information Routes of Entry Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Toxicity to Animals Chronic Effects on Humans other Toxic Effects on Humans Inhalation. Ingestion. Acute oral toxicity (LD50): >2000 mg/kg [Rat [information from vendor]]. Slightly hazardous in case of skin contact (irritant), of ingestion, of inhalation. Potential Health Effects: Skin: It is not considered an irritant for immediate (acute exposure). However, prolonged or repeated skin contact may cause skin irritation. It is recommended that prolonged contact with skin be avoided. Eyes: Although this product is not known to cause eye irritation, it is recommended that direct contact with eyes be avoided since in may cause mechanical eye irritation. Inhalation: This product may produce dust. It may cause respiratory tract irritation. Breathing small amounts of this material during normal handling is not likely to cause harmful effects. It may cause sensitization/allergic reaction by inhalation in hypersensitive individuals. Ingestion: It is not known to result in significant adverse health effects. It may cause gastrointestinal tract irritation. Section 2. Ecological Information Ecotoxicity BOD5 and COD Products of Biodegradation Toxicity of the Products of Biodegradation the Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
a-amylase Page Number: 5 Section 3. Disposal Considerations Waste Disposal Waste must be disposed of in accordance with federal, state and local environmental control regulations. Section 4. Transport Information DOT Classification Not a DOT controlled material (United States). Identification Not applicable. Special Provisions for Transport Not applicable. DOT Section 5. Other Regulatory Information and Pictograms Federal and State Regulations California Proposition 65 Warnings Other Regulations TSCA 8(b) inventory: a-amylase California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: No products were found. California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. EINECS: This product is on the European Inventory of Existing Commercial Chemical Substances. Other Classifications WHMIS (Canada) Not controlled under WHMIS (Canada). DSCL (EEC) R42- May cause sensitization by inhalation. S22- Do not breathe dust. S24- Avoid contact with skin. S36/37- Wear suitable protective clothing and gloves. HMIS (U.S.A.) Health Hazard Fire Hazard 0 National Fire Protection Association (U.S.A.) Health 0 Flammability Personal Protection E Specific hazard WHMIS (Canada) DSCL (Europe) TDG (Canada)
a-amylase Page Number: 6 ADR (Europe) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses. Section 6. Other Information MSDS Code References Other Special Considerations A874X Validated by Sonia Owen on 8/8/2008. Verified by Sonia Owen. Printed 9/9/2008. CALL (30) 56-8000 Notice to Reader All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.