RegMed Forum Years BCRT October 06-07, 2016 Berlin. Program

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Thursday, October 06, 2016 Registration Foyer BBAW All Participants 08:15 08:45 Welcome and Overview / Opening Symposium Leibniz-Saal All Participants 08:45 Overview Hans-Dieter Volk, Georg Duda, Andreas Lendlein 08:50 Where Are We, Where Are We Going? Hans-Dieter Volk BCRT Charité Universitätsmedizin Berlin Session I Strategies for Supporting Regeneration after Bone/Muscle Injury Chair: Andrew Carr SAB Co-Chair: Georg Duda BCRT 09:10 Remaining Challenges in Musculoskeletal Regeneration: Induce Endogenous Repair Mechanism in Tendon Andrew Carr SAB University of Oxford, UK 09:35 Learning from Bone Regeneration Georg Duda BCRT Charité Universitätsmedizin Berlin 09:55 Extracellular Matrix Organization and Mineralization in Bone Regeneration Peter Fratzl MPI 10:10 Visualization of Bone Immune Interaction Anja Hauser DRFZ 10:25 Hereditary Forms of Bone Fragility and Treatment Strategies Uwe Kornak BCRT Charité Universitätsmedizin Berlin 10:40 Regenerative Strategies after Muscle Injury from Bench-to-Bedside and Reverse Tobias Winkler BCRT Charité Universitätsmedizin Berlin 11:00 Developing a new ECM Platform a Joint Industry and Basic Research Approach Ingo Heschel Matricel GmbH Ansgar Petersen BCRT Charité Universitätsmedizin Berlin 11:20 Coffee Break 1

Thursday, October 06, 2016 Session II Regenerative Approaches in Cardiovascular Diseases Chair: Stephane Heymans SAB Co-Chair: Carsten Tschöpe BCRT 11:40 Molecular Mechanism of Cardiomyopathy Stephane Heymans SAB Maastricht University Medical Centre 12:00 Inflammed Heart Targeted Therapies Carsten Tschöpe BCRT Charité Universitätsmedizin Berlin 12:15 CardAP A Unique Cell Type for Cardiac Muscle Regeneration Michael Sittinger BCRT Charité Universitätsmedizin Berlin Sophie Van Linthout BCRT Charité Universitätsmedizin Berlin 12:30 Lunch Break Poster Session Session III Regenerating / Reshaping the Immune System by Immune Cell Therapies Chair: Cliona Rooney SAB Co-Chair: Petra Reinke BCRT 14:00 Immune Cell Therapy Cliona Rooney SAB Baylor College of Medicine Houston, USA 14:25 Transgenic T Cells for Immunotherapy Wolfgang Uckert MDC 14:45 Regulatory T Cell Therapy from Bench-to-Bedside Petra Reinke BCRT Charité Universitätsmedizin Berlin 15:05 Selection and Expansion of Long-Lived T Cells for Sustained Immune Regeneration Michael Schmück-Henneresse BCRT Charité Universitätsmedizin Berlin 15:20 CD8+ Treg: Old, New Players in Immune Tolerance Ignacio Anegon SAB CHU des Nantes 15:40 Immune Cell Therapy an Industrial Point of View Lothar Germeroth Juno Therapeutics, Inc. 16:00 Coffee break 2

Thursday, October 06, 2016 17:00 Opening Ceremonial Act (for invited guests only) and Scientific Get-Together (open) Welcome Dr. Torsten Fischer Head of the Public Relations Department of Helmholtz-Zentrum Geesthacht 17:05 Short Welcoming Speech by Representative of the Land of Brandenburg Carsten Feller Brandenburg Ministry for Science, Research and Culture 17:20 Speech by Board of Charité Universitätsmedizin Berlin Karl Einhäupl Chief Executive Officer of the Charité Universitätsmedizin Berlin 17:35 Speech by Executive Board of HZG Michael Ganß Administrative Director of Helmholtz-Zentrum Geesthacht 17:50 Short Welcoming Speech by Representative of the Berlin Institute of Health Axel Pries Extraofficial Member of the Executive Board Berlin Institute of Health Dean of the Charité Universitätsmedizin Berlin 18:05 Word of Thanks and Ceremonial Opening Board of Directors of the Berlin-Brandenburg Center for Regenerative Therapies 18:25 Laudatory Speech Jörg Vienken SAB 18:40 BCRT Gets the Blues Albrecht Wendel SAB Karlsson Penthouse (Zugang über Wissenschaftsforum Berlin) Markgrafenstrasse 37 10117 Berlin 20:00 Opening of the Buffet by the Board of Directors 3

Friday, October 07, 2016 Registration Foyer BBAW All Participants 08:00 08:30 Session IV Biomaterials and Regeneration Chair: Jörg Vienken SAB Co-Chair: Andreas Lendlein BCRT HZG Multifunctional Polymer-Based Biomaterials 08:30 International Approach to Biomaterial Research and Translation Yakai Feng Tianjin University, China 08:55 Biomaterials and Translational Technologies Andreas Lendlein BCRT HZG 09:15 Biomaterial-Induced Stem Cell Modulation/ Differentiation Nan Ma BCRT HZG 09:30 Hemocompatibility of Biomaterials towards a Personalized Approach Friedrich Jung BCRT HZG Minimally Invasive Procedures and Gentle Treatments 09:45 Cardiovascular Implant Design from Clinical Need to Device Design Markus Reinthaler BCRT HZG Ulf Landmesser Charité Universitätsmedizin Berlin 10:00 Cardiovascular Devices from Conception to Broad Clinical Application Bruno Scheller InnoRa GmbH Tissue Regeneration 10:20 Cardiac Patch (Crossfield F/B) Christof Stamm BCRT Deutsches Herzzentrum Berlin 10:35 Multimodal Evaluation of Bone Regeneration Induced by a 3D Architectured Hydrogel Philipp Lohmann Forschungszentrum Jülich, Institute of Neuroscience and Medicine 10:50 Coffee Break 4

Friday, October 07, 2016 Session V Precision Medicine in Regenerative Medicine Chair: Ignacio Anegon SAB 11:10 Application of Biomarkers in RegMed Hans-Dieter Volk BCRT Charité Universitätsmedizin Berlin 11:30 Genomics in RegMed Stefan Mundlos BCRT Charité Universitätsmedizin Berlin 11:50 Translational Bioinformatics Tool for Linking Phenotype and Genotype Tomasz Zemojtel BCRT Charité Universitätsmedizin Berlin 12:10 Lunch Break Poster Session Session VI Advanced Disease Models and Technologies Chair: Albrecht Wendel SAB Co-Chair: Uwe Marx TissUse GmbH 13:10 Advanced In Vitro Models Using Human-on-the-Chip Technology Uwe Marx TissUse GmbH 13:35 Stem Cell Core Unit Berlin Harald Stachelscheid BCRT Charité Universitätsmedizin Berlin N.N. 13:50 In Vitro Nephrogenesis Using Human ips Cells Krithika Hariharan BCRT Charité Universitätsmedizin Berlin 14:05 Immunogenicity and Immunomodulation of Human ips Cells and their Derivatives Bella Rossbach BCRT Charité Universitätsmedizin Berlin 14:20 How Does our Mouse Models under Standard Housing Conditions Reflect the Real Life? Kerstin Mühle BCRT Charité Universitätsmedizin Berlin 14:35 Are Large Animal Models the Better Human Models? Evi Lippens BCRT Charité Universitätsmedizin Berlin 14:50 Replacement of Animal Experiments: No Fast-Selling Item Albrecht Wendel SAB 5

Friday, October 07, 2016 15:05 Coffee Break 15:25 Award for Paper of the Year 2015 Werner Wolf SAB Klaus von der Mark SAB 15:55 End 15:55 Meeting BCRT Board with SAB 6