Injectable Soft Tissue Fillers: Practical Applications. Karol A Gutowski, MD, FACS

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Injectable Soft Tissue Fillers: Practical Applications Karol A Gutowski, MD, FACS

Disclosures Instructor for Suneva (Bellafill) Will describe off-label uses Will use brand names

Injectable Tissue Filler Options Silicone Animal Collagen (Zyderm, Zyplasty, Evolence) Fat Stimulators PLLA (Sculptra) PMM (Bellafill) CaHA (Radiesse) Human Collagen (CosmoDerm, CosmoPlast, Fascian, Autologen, Cymetra, LaViv) Hyaluronic Acids (Juvederm & Voluma, Restylane, Belotero) Reversible

*Mathematical description of product s tendency to be deformed elastically May not match clinical results Elastic Modulus* (G prime) More lift Less lift Less spread More spread

Filler Rheology

Restylane Product Particle Size Silk Restylane Lyft All 3 have 20 mg HA per ml Particle size is different

Particle Size & Injection Depth Silk Lyft Restylane

Water Absorption Prevelle Silk Less Swelling Restylane and Perlane Juvéderm Ultra Plus More Swelling

Where & What to Inject Neuromodulator (Botox, Dysport, Xeomin) For wrinkles with movement Filler (Juvederm, Restylane) For wrinkles at rest For small volume deficits Stimulator (Sculptra, Bellafill) For replacing regional volume loss

1 Year Personal Experience Injectable patient encounters 1016 Neuromodulator only 416 Filler only 291 Neuromodulator + filler 271 Filler touch up 38 Typical filler volume used 2-3 cc

Fillers Used & Locations Most Common Sites Malar & cheeks Lips & perioral Tear troughs & periorbital Nasolabial folds Temples, hands, nose Most Common Filler Radiesse Restylane products Bellafill Juvederm products Belotero Sculptra

Practice Overview Karol Maggie Chris Rhonda Suzie MD PA PA RN RN Instructor Bellafill - Bellafill Restylane - Patients per Month 50 120 40 60 20 Ave Volume (cc) 2 to 3 2 to 3 5 to 7 2 to 3 3 Restylane Products 25% 65% 20% 90% 70% Juvederm Products 5% 20% - 10% 30% Radiesse 50% 5% - - - Bellafill 15% 5% 80% - - Belotero 5% 5% - - - Most Common Area Malar Lips, Malar Malar Lips, Malar Malar, Lips

Target the Volume Loss

Basic Set Up

Block & Tackle the Face Jesper Sorensen Zide 1998

Injection Technique Target the correct level Mid to deep dermis Low G HAs Subcutaneous PLLA, CaHA, PMMA Higher G HAs Deep/preperiosteal High G HAs, CaHA

Example: Tear Trough Serial Puncture

Linear Threading Example: Nasolabial Fold

Fanning Example: Deep Malar Elevation

Cross Hatching Example: Lateral Lip Frown

Tunneling or Linear Threading Placement at dermal/subdermal junction

Proper Dermal Injection Too Superficial Too Deep Correct Placement Needle lifted

Blunt Injection Cannulas

Blunt Injection Cannulas

Patient Selection Volume Loss Fillers Volume Descent Facelift

The Power of Volume After fat grafting

The Power of Volume After fat grafting Rebuild the deep volume with fat Then fill fine lines with a filler

Hollow Temples

Lower Lids & Tear Troughs Proceed with Caution

Tear Trough Asymmetry Topical anesthetic Restylane (Moderate G ) 30G needle 80% correction

Tear Trough Asymmetry

Mild Fat Pad Herniation

Mild Fat Pad Herniation Topical anesthetic Juvederm (Low G ) 30G needle 80% correction

Fat Pad Herniation Correction

Fat Pad Herniation Correction

Fat Pad Herniation Correction

Fat Pad Herniation Correction

Tear Trough & Malar Support

Tear Trough & Malar Support

Tear Trough & Malar Support

Tear Trough & Malar Support Restylane

Tear Trough & Malar Support Restylane Radiesse

Tear Trough & Malar Support

Tear Trough & Prominent Orbicularis

Tear Trough & Prominent Orbicularis Juvederm Low G

Tear Trough & Prominent Orbicularis Juvederm 1:1 Saline Juvederm Low G

Tear Trough & Prominent Orbicularis

Lower Lid & Midface

Lower Lid & Midface Belotero 1cc per side

Tear Trough & Lower Lids Inject on periosteum Expect edema & ecchymosis Under correct Touch up in 2 weeks Prolonged edema Treat early Hyaluronidase May persist for years Not for novice injectors

Malar & Cheek Best Bang for the Buck

Hollow Cheeks

Hollow Cheeks After 1 vial Sculptra to each cheek

Malar & Cheeks Malar High G (Radiesse or Lyft, Bellafill for long-term) 0.1 cc needle bolus at 2-4 points on periosteum at malar prominence Massage & shape to desired form Cheeks Moderate to high G blunt cannula injection Subcutaneous fanning or cross-hatching Treat before nasolabial folds

Nasolabial Folds After Malar Correction

Mild Nasolabial Folds

Mild Nasolabial Folds Low to moderate G Blunt cannula Subdermal injection

Mild Nasolabial Folds Before and after Bellafill to nasolabial folds 2 syringes (Right 1.2 cc, Left 0.5cc)

Moderate Nasolabial Folds Before and after Juvederm Ultra Plus to nasolabial folds 1 syringe (Right 0.45 cc, Left 0.55cc)

Moderate Nasolabial Folds Before and after 1.5 cc Radiesse to nasolabial folds

Moderate Nasolabial Folds Before and after 1.5 cc Radiesse to nasolabial folds

Lips & Perioral

Lips & Corners

Lip Vermilion Moderate G 30G needle (or cannula) Serial puncture

Lip Corners Moderate to high G 29G or 30G needle Cross hatch

Lips & Corners 2 cc Restylane

Thin Lips & Lip Lines 1 cc Restylane

Marionette Lines

Marionette Lines Moderate to high G 27G or 29G needle Fanning

Marionette Lines 0.25 cc Radiesse/side

Marionette Lines

Marionette Lines Moderate to high G 27G or 29G needle Fanning

Marionette Lines Moderate to high G 27G or 29G needle Cross hatch as needed

Marionette Lines 1 cc Restylane

Gummy Smile

Gummy Smile - Neuromodulator

Consider Central & Corner Lip Lift 1 cc Radiesse

Neuromodulator for Lip Lines

Neuromodulator for Lip Lines 2u BTA per side

Neuromodulator for Lip Lines 1 cc Radiesse

Filler for Lower Lip Support 2 cc Juvederm Plus

Chin Fine Lines & Creases 1 cc Hydrell Intradermal

Neuromodulator for DAO BTA 5 u DAO + 1 cc Restylane

Lips, Perioral, Cheeks 4.6 cc Bellafill

Lips, Perioral, Cheeks 4.6 cc Bellafill

Jaw Line & Pre Jowl Sulcus Small Volume, Big Result

Mild Jowls

Mild Jowls Moderate to high G 27G needle 0.1 cc boluses pre-periosteal Massage as needed

Mild Jowls 0.3 cc Radiesse/side

Mild Jowl & Pointing Chin 0.4 cc Radiesse/side

Mandible Angle Enhancement 1.2 cc Bellafill/side

Nose Proceed with Caution

Bellafill Rhinoplasty

Restylane Rhinoplasty

Restylane Rhinoplasty

Restylane Rhinoplasty

Hands Why Stop at the Face?

Aging Hand

Aging Hand High G Blunt cannula Linear threading Massage to position

Restore Dorsal Hand Fullness Before and after 1.5 cc Radiesse to dorsum (FDA Approved)

Restore Dorsal Hand Fullness Before and after 1.5 cc Radiesse to dorsum (FDA Approved)

Fat Graft Dorsal Volumization Before and 6 months after Fat Grafting to dorsum

Fat Graft Dorsal Volumization Before and 6 months after Fat Grafting to dorsum

Acne Scars

Atrophic Acne Scars Rolling scars improved with skin traction Bellafill FDA Approved for Acne Scars

Scars Improved with Traction

Patient Selection Study: Grade 3 & 4 rolling acne scars

Acne Scars Treatment Before 6 Months 12 months Before 6 Months 12 months 0.8 to 1.6 cc Bellafill Rolling acne scars that improve with stretch

Putting it Together

Facial Volumization

Start Superior & Lateral 0.8 cc syringe 40 to 50 passes 27G blunt cannula Supraperiosteal Microdroplets

Volumize Inferior Orbit & Malar Area 0.8 cc syringe 40 to 50 passes 27G blunt cannula Supraperiosteal Subdermal Fanning

Treat Hollow Cheek 0.8 cc syringe 40 to 50 passes 27G blunt cannula Supraperiosteal Subdermal Subdermal Cross Hatching

Move to Lower Face

Lower Face 0.8 cc syringe 40 to 50 passes 27G blunt cannula Subdermal Fanning & Cross Hatching

Facial Volumization: Bellafill 4.6 cc

Realistic Expectations!

Injectable Soft Tissue Fillers: Practical Applications Karol A Gutowski, MD, FACS