ANSI Z400.1/Z129.1-2010 (United States, Canada, Mexico) Safety Data Sheet Buffer For Deactivation Fluid SECTION 1: Identification of the substance/mixture and of the company/undertaking Product Name Specific use(s) Recommended Use Supplier Address Buffer For Deactivation Fluid APTIMA HIV-1 RNA Qualitative Assay, APTIMA HCV RNA Qualitative Assay, APTIMA CT Assay, APTIMA GC Assay, APTIMA COMBO 2 Assay, APTIMA Trichomonas vaginalis Assay, APTIMA HPV Assay, PROGENSA PCA3 Assay In vitro diagnostic Hologic Gen-Probe Incorporated 10210 Genetic Center Drive San Diego, CA 92121-4362 For further information, please contact Technicalsupport@gen-probe.com Emergency Telephone Chemtrec, U.S. 1-800-424-9300, International +1-703-527-3887 SECTION 2: Hazards identification Color Physical state OSHA Regulatory Status Principle Routes of Exposure Potential health effects Acute toxicity Eyes Skin Inhalation Ingestion Chronic toxicity Aggravated Medical Conditions Colorless Liquid While this material is not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200), this MSDS contains valuable information critical to the safe handling and proper use of the product. This MSDS should be retained and available for employees and other users of this product. Inhalation. Skin Contact. Eye contact. None known. SECTION 3: Composition/information on ingredients The product contains no substances which at their given concentration, are considered to be hazardous to health. Page 1 / 5
SECTION 4: First aid measures Eye contact Skin Contact Inhalation Ingestion Note to physicians In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If symptoms persist, call a physician. Wash skin with soap and water. If symptoms persist, call a physician. Remove to fresh air. If symptoms persist, call a physician. Clean mouth with water and drink afterwards plenty of water. If symptoms persist, call a physician. Treat symptomatically. SECTION 5: Firefighting measures Flammability Suitable Extinguishing Media Protective equipment and precautions for firefighters Not flammable. Use extinguishing agent suitable for type of surrounding fire. As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. SECTION 6: Accidental release measures Personal precautions Methods for containment Methods for cleaning up Use personal protective equipment as required. Prevent further leakage or spillage if safe to do so. Soak up with inert absorbent material. Dispose of contents/containers in accordance with local regulations. SECTION 7: Handling and storage Precautions for safe handling Advice on safe handling Storage No known effects under normal use conditions. Handle in accordance with good industrial hygiene and safety practice. Avoid contact with skin and eyes. Wash hands thoroughly after handling. Use personal protection recommended in Section 8. Store in accordance with local regulations. Use appropriate containment to avoid environmental contamination. SECTION 8: Exposure controls/personal protection Other Information Vacated limits revoked by the Court of Appeals decision in AFL-CIO v. OSHA, 965 F.2d 962 (11th Cir., 1992) Engineering Controls Provide adequate ventilation. Showers. Eyewash stations. Personal protective equipment (PPE) Eye/face protection Wear safety glasses with side shields (or goggles). Skin and body protection Wear suitable protective clothing. Hand Protection Wear protective gloves. Respiratory protection Not Applicable. SECTION 9: Physical and chemical properties Page 2 / 5
Information on basic physical and chemical properties Physical state Liquid Appearance Color Colorless Property ph Melting point/freezing point Boiling point/boiling range Flash point Evaporation rate Flammability (solid, gas) Flammability Limits in Air Upper flammability limits Lower flammability limit Vapor pressure Vapor density Relative density Solubility(ies) Partition coefficient Autoignition temperature Decomposition temperature Viscosity Explosive properties Oxidizing properties Values ~ 9.3 1.0 Remarks Method.. Stability Stable under recommended storage conditions Incompatible materials Conditions to avoid Hazardous Decomposition Products Possibility of Hazardous Reactions Hazardous polymerization Acute toxicity SECTION 10: Stability and reactivity SECTION 11: Toxicological information Chronic toxicity SECTION 12: Ecological information Ecotoxicity The environmental impact of this product has not been fully investigated. Chemical Name Algae/aquatic plants Fish Crustacea Page 3 / 5
Sodium Bicarbonate Sodium Hypochlorite 650: 120 h Nitzschia linearis mg/l EC50 8250-9000: 96 h Lepomis macrochirus mg/l LC50 static 0.4-0.8: 96 h Lepomis macrochirus mg/l LC50 static 2350: 48 h Daphnia magna mg/l EC50 SECTION 13: Disposal considerations Disposal of wastes Disposal should be in accordance with applicable regional, national and local laws and regulations. SECTION 14: Transport information DOT TDG ICAO (air) IATA IMDG SECTION 15: Regulatory information US Federal Regulations SARA 313 Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA). This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372. CWA (Clean Water Act) This product contains the following substances which are regulated pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42). Chemical Name CWA - Reportable CWA - Toxic Pollutants CWA - Priority Pollutants CWA - Hazardous Quantities Substances Sodium Hydroxide 1000 lb X Sodium Hypochlorite 100 lb X CERCLA This material, as supplied, contains one or more substances regulated as a hazardous substance under the Comprehensive Environmental Response Compensation and Liability Act (CERCLA) (40 CFR 302). Chemical Name Hazardous Substances RQs CERCLA/SARA RQ Reportable Quantity (RQ) Sodium Hydroxide 1000 lb RQ 1000 lb final RQ RQ 454 kg final RQ Sodium Hypochlorite 100 lb RQ 100 lb final RQ RQ 45.4 kg final RQ US State Regulations California Proposition 65 This product does not contain any Proposition 65 chemicals. U.S. State Right-to-Know Regulations This product may contain substances regulated by state right-to-know regulations. Chemical Name Massachusetts New Jersey Pennsylvania Sodium Hydroxide X X X Sodium Hypochlorite X X X International Regulations Page 4 / 5
Canada This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations (CPR) and the MSDS contains all the information required by the CPR. WHMIS Hazard Class Non-controlled International Inventories TSCA DSL NDSL EINECS ELINCS ENCS IECSC KECL PICCS AICS Does not Comply Does not Comply Legend TSCA - United States Toxic Substances Control Act Section 8(b) Inventory DSL/NDSL - Canadian Domestic Substances List/Non-Domestic Substances List EINECS/ELINCS - European Inventory of Existing Chemical Substances/European List of Notified Chemical Substances ENCS - Japan Existing and New Chemical Substances IECSC - China Inventory of Existing Chemical Substances KECL - Korean Existing and Evaluated Chemical Substances PICCS - Philippines Inventory of Chemicals and Chemical Substances AICS - Australian Inventory of Chemical Substances NFPA SECTION 16: Other information HMIS Health hazards 0 Flammability 0 Physical hazards 0 Personal protection - Revision Date 14-Jun-2013 Version 2 The information provided in this Material Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text. End of Safety Data Sheet Page 5 / 5