MATERIAL SAFETY DATA SHEET TWEEN 20 Section 1 - Chemical Product and Company Identification MSDS Name: Tween 20 Synonyms: Polyoxyethylene 20 sorbitan monolaurate, Polysorbate 20 Company Identification: SISCO RESEARCH LABORATORIES PVT. LTD. Andheri(East), Mumbai-400 093. Tel : 2687 2601/2687 8163/2687 8243 Fax : 2687 8241 Section 2 - Composition, Information on Ingredients CAS# Chemical Name Percent EINECS/ELINCS 9005-64-5 Tween 20 unlisted Section 3 - Hazards Identification Appearance: Caution! Target Organs: Potential Health Effects Eye: Ingestion: Inhalation: Chronic: Section 4 - First Aid Measures Eyes: Ingestion: Inhalation: Notes to Physician: EMERGENCY OVERVIEW Light amber to amber. May cause eye and skin irritation. May cause respiratory and digestive tract irritation. None. May cause mild eye irritation. May cause skin irritation. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause respiratory tract irritation. Adverse reproductive effects have been reported in animals. Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear. Treat symptomatically and supportively.
Section 5 - Fire Fighting Measures General Information: Extinguishing Media: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Section 6 - Accidental Release Measures General Information: Spills/Leaks: Use proper personal protective equipment as indicated in Section 8. Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Section 7 - Handling and Storage Handling: Storage: Use with adequate ventilation. Avoid prolonged or repeated contact with skin. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Keep from freezing. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store at around 20 C. Section 8 - Exposure Controls, Personal Protection Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits. Exposure Limits Chemical Name ACGIH NIOSH OSHA - Final PELs POLYSORBATE 20 none listed none listed none listed OSHA Vacated PELs: POLYSORBATE 20: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear safety glasses and chemical goggles if splashing is possible. Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Wear appropriate protective gloves and clothing to prevent skin exposure. Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Respirators: Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or
Section 9 - Physical and Chemical Properties European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Physical State: Liquid Appearance: Pale yellow liquid Specific Gravity/Density: 1.105-1.107 Molecular Formula: C 58 H 114 O 26 Molecular Weight: 1226.78 Section 10 - Stability and Reactivity Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizers Hazardous Decomposition Products: Carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - Toxicological Information RTECS#: CAS# 9005-64-5: TR7400000 LD50/LC50: CAS# 9005-64-5: Oral, mouse: LD50 = >33 gm/kg; Oral, rat: LD50 = 36700 ul/kg; Carcinogenicity: CAS# 9005-64-5: Not listed by ACGIH, IARC, NTP, or CA Prop 65. Other Studies: Section 12 - Ecological Information Ecotoxicity: Environmental: Physical: Other: No data available. No information available. No information reported. No information available. None. Section 13 - Disposal Considerations Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed.
Section 14 - Transport Information Shipping Name: Hazard Class: UN Number: Packing Group: US DOT Not regulated as a hazardous material Canada TDG No information available. Section 15 - Regulatory Information US FEDERAL TSCA CAS# 9005-64-5 is listed on the TSCA inventory. Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List. Chemical Test Rules None of the chemicals in this product are under a Chemical Test Rule. Section 12b None of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA. CERCLA Hazardous Substances and corresponding RQs None of the chemicals in this material have an RQ. SARA Section 302 Extremely Hazardous Substances None of the chemicals in this product have a TPQ. Section 313 No chemicals are reportable under Section 313. Clean Air Act: Clean Water Act: OSHA: STATE California Prop 65 European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. None of the chemicals in this product are listed as Hazardous Substances under the CWA.None of the chemicals in this product are listed as Priority Pollutants under the CWA.None of the chemicals in this product are listed as Toxic Pollutants under the CWA. None of the chemicals in this product are considered highly hazardous by OSHA. CAS# 9005-64-5 is not present on state lists from CA, PA, MN, MA, FL, or NJ. California No Significant Risk Level: None of the chemicals in this product are listed.
Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 9005-64-5: 1 Section 16 - Additional Information SISCO RESEARCH LABORATORIES provides the information contained herein in good faith but makes no representation as to its comprehensiveness or accuracy. This document is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.