A NEW VISION OF PERFECTION

A NEW VISION OF PERFECTION

A pioneer in Marine Intelligence, the THALGO Laboratory has been exploring the Oceans for over 50 years to innovate and revolutionise the world of Professional Cosmetics. Thanks to this innovative scientific research, and in close collaboration with skin engineering specialists, including 3 renowned Dermatologists and 1 University Professor, the THALGO Laboratory is venturing into a new area of expertise: The first medically-inspired professional cosmeceutical skincare range with patented Mésolift Marin Developed according to our core values, these products contain advanced molecules used in dermatology and outstanding marine ingredients to: offer major innovations that break away from traditional cosmetics deliver a rigorous cosmetic "treatment" capable of producing visible effects on the skin guarantee the unique effectiveness of our products with proven and measured results. 2

Mésolift Marin is a non-invasive version of the antiageing mesotherapy technique. The bio-regenerative "infusion" compensates for deficiencies in the body s tissues to boost skin cells metabolism and maintain youthful-looking skin. A PATENTED COMBINATION 34 POLY-REVITALISING NUTRIENTS 2 B-VITAMINS, 14 MINERALS, 18 AMINO ACIDS Cellular regenerating ingredients + CELLULAR ANTI-AGEING nucleoside Stimulates the renewal of skin cells ANTI-AGEING HYALURONIC ACID HIGH PENETRATION Plumping, lifting, hydrating VECTORISED THANKS to cutting-edge TECHNOLOGY Mésolift Marin is encapsulated at the centre of the Biosphere*, a unique transport system that releases the complex into skin cells like an "injection". 3 The intelligent concentric structure of this Biosphere propels the bio-regenerative formula right to the heart of the target area. It is able to control its biodistribution, enabling a sustained release for up to 48 hours. This ensures optimal infusion at the deeper layers of the epidermis and an unparalleled bioavailability. *Biosphere: Biocompatible vectorisation system.

EXTRAORDINARY PERFORMANCE FOR AN ANTI-AGEING RESULT Proven and highly significant polyrevitalising effects on youthfulnessboosting cells called fibroblasts 9 %* boost in cellular metabolism 72 hours after a dose of Mésolift Marin Remarkable reactivation of the skin s antiageing functions 373 % more Collagen* synthesised 48 hours after a dose of Mésolift Marin. This protein supports the skin s structure. 121 % more Elastin * synthesised 72 hours after a dose of Mésolift Marin. This protein guarantees the skin s resilience and elasticity MéSOLIFT MARIN accelerates self-regeneration for youthful-looking, firm and radiant skin 4 *Tested in vitro effectiveness of Mésolift Marin (0.28%) on fibroblasts cultivated in the presence of a collagenic matrix in a normal nutritive environment.

Loss of radiance, uneven skin tone, rough microsurface, thick skin texture, dilated pores, localised imperfections, residual marks... All these negative aspects contribute to altering the appearance of the skin. Poor skin quality can be a disorder in its own right, caused by multiple factors that affect all skin types. This is why the THALGO Research Centre has developed a cutting-edge medi-cosmetic programme with Mésolift Marin: Rénovation Radicale The first corrective solution designed to target factors that cause imperfections and irregularities, for youthful-looking, smooth and radiant skin. 5

Unparalleled efficacy, based on patented scientific technology Néo-Skin capable of reconstructing healthy and youthful-looking skin The THALGO Laboratory has identified the main cause of progressive deterioration of the skin s texture: excessive activity of the cells that maintain the skin s integrity. Néo- Skin is a unique combination of 3 highly active extracts specifically designed to regenerate skin. They regulate the cells disruptive activity by targeting sebaceous gland dysfunction to gradually restore the skin s original quality. 6

Rénovation Radicale A 3-step cosmetic "treatment" capable of producing visible results The Rénovation Radicale "consultation" begins with a skin diagnosis aimed at closely analysing the condition of the skin to provide the most suitable corrective cosmetic "treatment". The "treatment" is tailored to perfection with a series of three steps designed to reconstruct ideal skin quality. 7

1 Renovating peel, a key step in the renovation and regeneration of the skin. The THALGO Laboratory has combined 3 highly effective acids in increasing concentrations (8-22.5%) within an optimal ph range (between 2.8 and 2.4) in 3 formulas, depending on the intensity of the problem observed. 2 Bio-regenerative infusion. This polyrevitalising infusion of Active Oxygen in a 5% dose and Pure Mésolift Marin in a 10.2% concentration boosts skin cells metabolism and maintains the appearance of youthful-looking skin. 3 Corrective intervention, personalised via the application of high performance hybrid products: two mask "treatments" with a high dose of serum to regulate and resurface the skin. 4 sessions of cosmetic "treatments" recommended and up to 6 sessions for more severe skin problems, alternating long "treatments" (55 mins) and short "treatments" (30 mins), for a progressive course that respects the skin. 8

Significant results certified by a Dermatologist 100% SATISFACTION* Improved skin quality Reduced imperfections Refined skin texture Clear and radiant complexion Noticeable correction of all aspects of poor skin quality: Smoother skin, clearer complexion and more even skin tone.* Reduction in imperfections, tightened pores.* BEFORE "TREATMENT" AFTER 6 "TREATMENTS" AND 2 WEEKS OF REST A clinical study has shown that the skin s roughness is significantly reduced by 14.9% ** BEFORE "TREATMENT" AFTER "TREATMENT" 9 *Self-assessment by 15 volunteers aged 40-50 who received alternating long and short "treatments" over 6 weeks (Rénovation Radicale "treatment" combined with a Grade 3 facial peel). ** Biometrological measurements on 15 volunteers - fringe projection.

Rénovation Radicale A cosmetic "post-treatment" prescription for use at home 10

PRO-REGULATOR MAKE-UP REMOVER This high performance gel-in-oil with exclusive lipophilic technology removes make-up and impurities and reduces shine while restoring high quality sebum. Actions Highly effective make-up removal with a combination of cleansing agents that "trap" oils and effectively dissolve make-up Restores sebum quality through the concerted action of 3 oils that protect surface lipids to guarantee high quality sebum Proven effectiveness for more than 8 out of 10 women* > Absorbs all the skin s oily residues and impurities: 90% > Healthier skin: 89% > Removes make-up perfectly: 79% Morning and night. 11 *Self-assessment on 19 volunteers with combination or oily skin - Results after 28 days of using the product.

PRO-RENEWAL CLEANSER This exfoliating mousse enriched with revitalising marine minerals cleanses, unclogs pores, refines skin tone and gradually reveals the skin s radiance. Actions Gradual exfoliation thanks to the "Papain/Salicylic Acid" duo which cleans blocked pores, refines skin tone and boosts radiance Marine remineralisation with a brown alga, Macrocystis pyrifera, highly concentrated in minerals and protective amino acids A remarkable product performance* > Skin is perfectly cleansed: 100% > Gently exfoliates the skin: 91% > Restores a more even skin texture: 78% Morning and night. Avoid the delicate eye area. Do not use on sensitive and/or irritated skin. *Self-assessment on 22 volunteers with combination or oily skin - Results after 28 days of using the product. 12

INTENSIVE PEEL 1 7 days to renewed skin. A dual renovating action for a spectacular skin result: persistent roughness is reduced, skin tone is smoother and more refined and the complexion is noticeably clearer. Actions Enzymatic exfoliation with Papain [5%], a high tolerance exfoliating agent that boosts the skin s radiance as effectively as Glycolic Acid Chemical exfoliation with stabilised vitamin C [3%], which is more effective than ordinary vitamin C and perfects the skin s surface by eliminating pigmentation and accelerating cellular renewal Soothing neutralisation thanks to Laminaria ochroleuca algae, which soothes and regulates the appearance of redness A visible skin result in 7 days* > Significant improvement of the skin s microsurface: roughness is reduced by up to +35.3% T0 R = 37.65mm T 7 days = 24.3mm Every evening for 7 consecutive days. Waiting time: 2 to 5 mins. Rinse with water. 13 *Clinical study on 18 volunteers Biometrological measurements Assessment of the condition of the skin s micro-surface (roughness) using surface imaging and fringe projection Assessment of the complexion s radiance using colourimetry Assessment of the effectiveness of cosmetic qualities with a questionnaire. Best results observed 7 days after using the product - Average value: 10.3% // 1 Superficial Peel.

DETOX REGENERATOR One drop to boost the skin s bio-regeneration. Ultra-concentrated in Mésolift Marin, this antiageing "infusion" is complemented by a powerful detoxifying action to reactivate skin cells metabolism and maintain youthful-looking skin. Actions Marine poly-revitalisation via Mésolift Marin [10.2%], which stimulates all the basic metabolic processes in cells Anti-ageing action produced by Mésolift Marin [10.2%], which has a significant stimulating effect on the synthesis of anti-ageing proteins Collagen and Elastin** Elimination of toxins with Lumisource, which reactivates autophagic detoxification to optimise the effects of Mésolift Marin Unparalleled performance in just 7 days* > More toned skin: 85% > Skin is re-energised and regains its vitality: 80% Morning and night for 7 consecutive days before using daily skincare products. Avoid the delicate eye area. *Self-assessment by 20 volunteers with dull complexions and tired-looking features. **Tested in vitro Effectiveness of Mésolift Marin (0.28%) on fibroblasts cultivated in the presence of a collagenic matrix in a normal nutritive environment. 14

NORMALISER CREAM-SERUM SEVERE IMPERFECTIONS The cosmeceutical formula is as concentrated as a serum and fundamentally rebalances the quality of the skin to cleanse, refine skin tone, tighten pores and reduce imperfections. Actions Renovation of the skin thanks to Néo-Skin [6%], which reconstructs optimum skin quality Reduction of imperfections via the improvement of sebum quality, thanks to the antimicrobial action of Totarol and stabilised Omega 6, which rebalances the composition of lipids in the skin s surface Marine poly-revitalisation via Mésolift Marin [3%], encapsulated at the centre of the Biospheres for maximum infusion into the epidermis A remarkable product performance* > Smoother-feeling skin: 85% > More even skin tone: 80% > Healthier skin: 80% Morning and night. 15

RESURFACER CREAM-SERUM SEVERE IRREGULARITIES This multi-perfecting cosmetic product is as concentrated as a serum and targets persistent irregularities on the skin to recreate optimum skin texture and a more even skin tone with a matte finish. Actions Renovation of the skin thanks to Néo-Skin [2%], which reconstructs optimum skin quality. Its action is complemented by Bakuchiol, which works like a retinoid to intensively purify the skin Surface correction with Hexylresorcinol, a powerful brightening agent that corrects residual brown spots Marine poly-revitalisation via Mésolift Marin [3%], encapsulated in the Biospheres for maximum infusion into the epidermis A remarkable product performance* > More even skin tone: 85% > More uniform complexion: 75% > Tightened pores: 75% Morning and night. *Self-assessment by 20 volunteers ages 30-55 - Results after 28 days of twice-daily use. 16

SUNSCREEN SPF 50 + Non-comedogenic* sunscreen with SPF 50 +, enriched with a patented natural marine filter to provide the skin with invisible and optimal protection. Actions Maximum UV protection thanks to Sun Ytol Future [1%], a natural marine filter with broad spectrum UVA and UVB protection. This powerful anti-oxidant maintains the integrity of skin cells and is complemented by 5 organic filters to provide sun protection After applying the Intensive Peel or following a Rénovation Radicale professional cosmetic "treatment". Also before any sun exposure. 17 *Clinical study under dermatological control - Self-assessment by 22 volunteers with combination or oily skin - Results after 28 days of twice-daily use.

THALGO UK LTD Elgin House - 51 Millharbour - Docklands - London E14 9TD Tel: +44 (0)20 7512 0872 - Fax: +44 (0)20 7512 0871 E-mail: enquiry@thalgo.co.uk - www.thalgo.co.uk Join us on: www.facebook.com/thalgouk THALGO IRELAND UNIT 3 - Clonmore Business Park - Mullingar - Co Westmeath - Ireland Tel: +353 (0)44 933 4602 - Fax: +353 (0)44 933 0140 Email: customerservice@pharmed.ie - www.thalgo.ie THALGO AUSTRALIA - BLC Cosmetics Pty Ltd P.O Box 261 Artarmon NSW 1570 9-15 Carlotta Street, Artarmon - NSW 2064 Tel: +61(0)2 9430 2200 E-mail: info@blccosmetics.com - www.thalgo.com.au LT 15068 - Photos : C. LAGEL - J. C. RECHT - J. MENU