Made in France - Marque déposée Laboratoires FILORGA - 10 rue de Vézelay Paris Tel. :

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Made in France - Marque déposée Laboratoires FILORGA - 10 rue de Vézelay - 75008 Paris Tel. : 01 42 93 94 00 www.filorga.com BRO034V002

1 st global anti-ageing peeling without social eviction Brightness, wrinkles, imperfections, brown spots

Chemical superficial dermatological peeling in 4 steps with sequential ph variations. Traditional peelings lower and increase the skin s ph in a very sudden way. GlyKopeel is the first chemical superficial dermatological peeling in 4 steps, with sequential ph variations. By associating a first, preliminary step (Prepeel with a ph of 4.5) with a final repairing phase (mist with a ph of 6.5) we allow a gentle treatment that provides an immediate, visible result with no need for social eviction. PREPEEL Step 1 - ph 4.5-60 ml Glycolic acid: 5 % Kojic acid: 1 % Lipoamino acid: 1 % Camomile extract: 1 % Hamamelis extract: 1 % Glycyrrhizic acid: 0.1 % PEELING Step 2 - ph 2 to 0.8-60 ml Glycolic acid: 70 % max/ph 0.8 70 %/ph 1.6 50 %/ph 1.8 20 %/ph 2 Kojic acid: 5 % Bearberry extract: 1 % White mulberry extract: 1 % Vitamins A, C and E PostPeel Step 3 - ph 8.0-125 ml Glycerin: 20 % Sodium acid carbonate: 7 % Mist Step 4 - ph 6.5-50 ml Purified sea water: 10 % Brown algae oligosalts: 0.10 % Marine chitin: 0.5 % Marine keratosulfate: 0.25 % Anti-inflammatory herbal complex: 2% [Glycyrrhetinic Acid, Vitamin B (D-Panthenol), Allantoin] Hydrating herbal complex: 3 % [Fructose, Glycine, Niacinamide, Urea, Inositol] Directions GlyKopeel is recommended to treat wrinkles, loss of suppleness, dull complexion, hyperpigmentation, microcystic acne and skin imperfections. It visibly improves cutaneous state with no side effects.

ph STEP 1 STEP 2 STEP 3 STEP 4 8 6,5 4,5 PREPEEL ph 4.5 PostPEEL ph 8 MIST ph 6.5 1,6 PEELing ph 0.8-2 Prepare Exfoliate Neutralize Repair GLYKOPEEL is the first peeling with sequential variation of ph in 4 steps. purification and preparation to the peeling This solution contains cleansing, purifying substances (lipo-amino acid, camomile and hamamelis extracts, glycyrrhizic acid) as well as exfoliant, pigmentation removal substances (5% glycolic acid and 1% kojic acid). It reduces the acidity of the skin. PREPEEL purifies the epidermis by eliminating dead cells and sebum and optimises the action of GlyKoPeel peeling solution. e x f o l i a t i o n, s t i m u l a t i o n, c o r r e c t i o n, p r o t e c t i o n The PEELING comes in 3 glycolic acid concentrations and 4 ph levels: 70 %* with a ph of 0.8 and 1.6 ; 50 %* with a ph of 1.8 ; 20 % with a ph of 2. Choice of concentration is made according to skin and indication type (refer to protocol section for more details on selection and usage of different Glykopeel treatments). This keratolytic, exfoliating solution increases dermal permeability and improves penetration of stimulating active ingredients, anti-wrinkle, brown spot correctors and anti-radical protectors. * Concentrations at 70 % and 50 % are exclusively reserved to medical usage. neutralisation and hydration POSTPEEL is essential for neutralising the action of the glycolic acid quickly, hydrating the epidermis superficially and regulating the ph of the skin. POSTPEEL has to be applied during 2 to 6 minutes after the PEELING upon the length of the peeling. anti-ageing and anti-inflammatory action The Mist is a genuine concentrate of marine agents and mineral extracts of marine algae, and it balances the cutaneous ecosystem by adjusting its ph at 6.5, mineralising it and toning it. This isotonic MIST is also a calming and moisturising agent due to the combined presence of marine chitin and marine keratosulfate. The Mist procures a great sensation of freshness at the end of the peeling. Contraindications Do not use on irritated areas, facial herpes, cutaneous allergy or after taking retinoids (or any other potentially irritating substances). Do not perform any epilation including epilation by electrolysis on the area to be treated a week prior to the treatment. Do not shave the area to be treated anytime later than four hours prior to treatment.

anti-ageing superficial chemical peel Protocol THE TYPE OF CHEMICAL PEEL CHOICE DEPENDS ON THE PATIENT S INDICATION AND SKIN TYPE. A gradual protocol during the recommended chemical peel sessions allows progressively increasing cutaneous tolerance and maximising the treatment s efficiency. GLYKOPEEL 20% is adapted to hypersensitive skins and can be performed by a medical attendant. GLYKOPEEL 50% is indicated for sensitive skins and during the first sessions of the treatment. GLYKOPEEL 70% enables a better efficiency level on more tolerant skins, used to chemical peels. GLYKOPEEL 70% MAX penetrates deeply inside the epidermis to provide more intense results whilst remaining a superficial peel. It is only adapted to very tolerant skins. GRADUAL PROTOCOL & APPLICATION DURATIONS Tolerance - Tolerance + Tolerance ++ 1 st session 2 nd session 3 rd session 4 th session 5 th session 20 % - 2 minutes 50 % - 2 minutes 70 % - 2 minutes 20 % - 3 minutes 50 % - 3 minutes 70 % max - 2 minutes 50 % - 4 minutes 70 % - 4 minutes 70 % max - 5 minutes 50 % - 5 minutes 70 % - 5 minutes 50 % - 5 minutes 70 % - 5 minutes Repeat GLYKOPEEL sessions: Every 5 to 7 days 3 to 5 sessions per treatment Twice a year Patient results Efficient and without requiring social eviction, GLYKOPEEL enables to appreciate the results immediately: Restores and brightens complexion Refines skin texture Smoothes over wrinkles Improves skin s elasticity Reduces pigment spots Tightens pores

Session 1 Session 2 Session 3 Session 4 Session 5 post peel Maintenance Revitalisation Phototype I-III GLYKOPEEL 50% - 2 min GLYKOPEEL 70% - 3 min GLYKOPEEL 70% MAX - 4 min Sun protection Vitamin C skincare 1 GLYKOPEEL 70% session 4 months later then every 6 months GLYKOPEEL PROTOCOL Anti-ageing correction Phototype III-VI Acne Pigment spots Skin irregularities GLYKOPEEL 50% - 2 min GLYKOPEEL 50% - 3 min GLYKOPEEL 50% - 3 min GLYKOPEEL 50% - 3 min GLYKOPEEL 70% - 3 min GLYKOPEEL 50% - 4 min GLYKOPEEL 70% - 4 min GLYKOPEEL 70% - 4 min GLYKOPEEL 70% Max - 4 min GLYKOPEEL 70% - 4 min GLYKOPEEL 70% - 5 min GLYKOPEEL 70% - 5 min GLYKOPEEL 70% Max - 5 min depigmenting skincare 6 weeks before GLYKOPEEL 70% MAX - 4 min GLYKOPEEL 70% Max 5 min + depigmenting skincare 6 weeks before GLYKOPEEL 70% MAX - 5 min GLYKOPEEL 70% MAX - 5 min Sun protection Vitamin C skincare Sun protection Sun protection Depigmenting skincare Sun protection Vitamin C skincare 2 GLYKOPEEL 70% MAX sessions 4 months later then every 6 months 1 GLYKOPEEL 70% session every 4 months 1 GLYKOPEEL 70% MAX session 4 months later then every 6 months 1 GLYKOPEEL 70% MAX session 4 months later then every 6 months

GLYKOPEEL is a dermatological chemical peel that visibly improves cutaneous condition, without requiring social eviction. GLYKOPEEL kit PRACTICAL: COMPLETE KIT FOR 25 TREATMENTS 60ml PREEPEEL 60ml PEEL solution - Glykopeel 20% - ph 2 - Glykopeel 50% - ph 1.8 - Glykopeel 70% - ph 1.6 - Glykopeel 70%MAX - ph 0.8 125ml POSTPEEL 50ml MIST 25 disposable applicators Dispenser Sequential ph variation in 4 phases: UNIQUE: THE 1 st CHEMICAL PEEL PROGRAMME IN 4 STEPS Preparation - ph 4.5 Exfoliation - ph 0.8 to 2 depending on concentration chosen Neutralisation - ph 8 Reparation - ph 6.5 New formula: 18 ingredients 4 TARGETED ACTIONS FOR AN EFFICENCY THAT IS IMMEDIATE: Improvement of RADIANCE and SMOOTHNESS PROGRESSIVE: reduction of WRINKLES and PIGMENT SPOTS WITHOUT SOCIAL EVICTION FILORGA guarantees total safety iso13485 certified laboratory, specialised in the production of CE marked medical devices. Buffered ph PEEL solutions: 3 concentrations, 4 ph levels all skin types: Sensitive to tolerant Phototypes I to IV All year long

IMMEDIATE, DURABL 18 ingredients for 4 anti-ageing actions 1exfoliation PURIFYING AND BRIGHTENESS ENHANCER GLYCOLIC ACID / PROPYLENE GLYCOL Glycolic acid is a pure AHA, materia medica quality controlled and buffered ph to ensure safety and efficiency. Comedolytic properties: it penetrates deeply inside the follicular canal where it disintegrates intercellular cement, eliminates the sebum plug and prevents its formulation. It therefore fights acne process. Keratolytic properties: it penetrates intercorneocytic cements to destroy them and eliminate the cornea layers of the epidermis. It therefore corrects cutaneous state: wrinkles and finelines are improved, pores are tightened, skin texture is refined and complexion is more radiant. Propylene glycol eases and spreads out glycolic acid penetration. protection 2ANTI-RADICAL, ANTI-INFLAMMATORY MULBERRY, BROWN ALGAE, VITAMIN E To eliminate any possible erythema, especially on most sensitive skins, Filorga has developed an exclusive anti-oxidant, anti-inflammatory cocktail to trap free radicals and inhibit the formation, amplification and reception of cytokines. This new GLYKOPEEL formula is therefore completely safe, very well tolerated and does not require social eviction. HYDRATING GLYCERIN, GLYCIN, NIACINAMIDE, UREA The hydrating cocktail provides the skin with the necessary elements for its suppleness and elasticity. By integrating POSTPEEL and MIST formulas, these factors provide immediate comfort to the skin following a chemical peel.

E EFFICIENCY 3 stimulation ANTI-WRINKLE AND LIFTING EFFECT GLYCOLIC ACID, VITAMINS A & C Vitamin A has a preventive and corrective action on signs of ageing: it stimulates collagen biosynthesis whilst inhibiting matrix metalloproteinase 1 (MMP-1). Its effects provide a size increase in elastic fibres, glycosaminoglycans and thickness of the dermis. Vitamin C activates cutaneous cellular metabolism by inducing fibroblast stimulation: it intervenes on proline and lysine hydroxylation action in hydroxyproline and hydroxylysine, essential to collagen synthesis. It therefore improves cutaneous tissue firmness and tonus. 4correction OF SUPERFICIAL PIGMENT SPOTS KOJIC ACID AND BEARBERRY Kojic acid and bearberry (arbutine) are powerful depigmenting active ingredients able to reduce melanin synthesis by inhibition of tyrosinase activity. The exclusive association of those two active principles insure progressive and visible treatment of pigmentation problems. vitamine c Ascorbic acid is renowned for its brightening properties; it prevents excessive melanin formation by inhibiting auto-oxidation of the dopa in dopamine. FOR OPTIMAL TREATING ACTION OF PIGMENTATION PROBLEMS, IT IS RECOMMENDED TO COMBINE THE GLYKOPEEL PROTOCOL TO LASER SESSIONS ON THE MOST NOTICEABLE PIGMENT SPOTS AS WELL AS A LONG TERM TOPICAL TREATMENT TO MAINTAIN RESULTS.

GLYKOPEEL 70% MAX A more radical efficiency without social eviction Exclusive formulation For an intensive treatment and radical results, FILORGA laboratories have developed the new GLYKOPEEL MAX. A poly-active formula composed of 18 ingredients, GLYKOPEEL range s signature. Concentration: 70% buffered glycolic acid with a ph of 0.8 EFFICIENCY OF A FREE GLYCOLIC ACID TOLERANCE OF A BUFFERED GLYCOLIC ACID Indications GLYKOPEEL MAX is recommended for tolerant skins to treat: Wrinkles and fine wrinkles Loss of elasticity Lack of brightness Hyper-pigmentation Microcystic acne Skin irregularities Direction for use GLYKOPEEL MAX offers a more radical result. It can be followed by minor side effects for 3 to 7 days: slight erythema, dryness and superficial desquamation. It is recommended not to have injections during the same session. An adapted post-peeling treatment can reduce potential discomfort linked to these side effects and avoid any social eviction.