Material Safety Data Sheet NFPA HMIS Personal Protective Equipment Health Hazard Fire Hazard See Section 5. Section. Chemical Product and Company Identification Page Number: Common Name/ Trade Name Polyethylene glycol 335 Catalog Number(s). YY23, YY467, YY25, YY646, PO25 Manufacturer SPECTRUM LABORATORY PRODUCTS INC. 4422 S. SAN PEDRO STREET GARDENA, CA 9248 CAS# RTECS 25322-68-3 TQ35 TSCA T S C A 8 ( b ) i n v e n t o r y : Polyethylene glycol 335 Commercial Name(s) PEG-75; Macrogol 335 Synonym Chemical Name Polyethylene Glycol CI# IN CASE OF EMERGENCY CHEMTREC (24hr) 8-424-93 Chemical Family Chemical Formula Supplier H(OCH2CH2)nOH SPECTRUM LABORATORY PRODUCTS INC. 4422 S. SAN PEDRO STREET GARDENA, CA 9248 CALL (3) 56-8 Section 2.Composition and Information on Ingredients Name CAS # Exposure Limits TWA (mg/m 3 ) STEL (mg/m 3 ) CEIL (mg/m 3 ) % by Weight ) Polyethylene glycol 335 25322-68-3 Toxicological Data on Ingredients Section 3. Hazards Identification Potential Acute Health Effects Potential Chronic Health Effects Slightly hazardous in case of skin contact (irritant, permeator), of eye contact (irritant), of ingestion, of inhalation. CARCINOGENIC EFFECTS: MUTAGENIC EFFECTS: TERATOGENIC EFFECTS: DEVELOPMENTAL TOXICITY: Repeated or prolonged exposure is not known to aggravate medical condition.
Polyethylene glycol 335 Page Number: 2 Section 4. First Aid Measures Eye Contact Skin Contact Serious Skin Contact Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 5 minutes. Cold water may be used. Get medical attention if irritation occurs. Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used. Inhalation Serious Inhalation If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Ingestion Serious Ingestion Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Section 5. Fire and Explosion Data Flammability of the Product Auto-Ignition Temperature Flash Points Flammable Limits Products of Combustion Fire Hazards in Presence of Various Substances May be combustible at high temperature. CLOSED CUP: 246 C (474.8 F). OPEN CUP: 279 C (534. 2 F). These products are carbon oxides (CO, CO2). Slightly flammable to flammable in presence of heat. Explosion Hazards in Presence of Various Substances Risks of explosion of the product in presence of mechanical impact: Risks of explosion of the product in presence of static discharge: Fire Fighting Media and Instructions Fire Hazards Explosion Hazards SMALL FIRE: Use DRY chemical powder. LARGE FIRE: Use water spray, fog or foam. Do not use water jet. Material in powder form, capable of creating a dust explosion. Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard. Section 6. Accidental Release Measures Small Spill Large Spill Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities.
Polyethylene glycol 335 Page Number: 3 Section 7. Handling and Storage Precautions Storage Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not breathe dust. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents, acids, alkalis. Keep container tightly closed. Keep container in a cool, well-ventilated area. Section 8. Exposure Controls/Personal Protection Engineering Controls Personal Protection Personal Protection in Case of a Large Spill Exposure Limits Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. TWA: (mg/m 3 ) from AIHA [United States] Inhalation Consult local authorities for acceptable exposure limits. Section 9. Physical and Chemical Properties Physical state and appearance Solid. (Powdered solid.) Odor Molecular Weight ph (% soln/water) 335 g/mole Taste Color White. Boiling Point >2 C (392 F) Melting Point 53 C (27.4 F) - 57 C. Critical Temperature Specific Gravity.926 (Water = ) Vapor Pressure Vapor Density Volatility Odor Threshold Water/Oil Dist. Coeff. Ionicity (in Water) Dispersion Properties See solubility in water. Solubility Soluble in cold water. Solubility in Water: 67% at 2 deg. C. Soluble in many organic solvents. Readily soluble in aromatic hydrocarbons. Only slightly soluble in aliphatic hydrocarbons. Section. Stability and Data Stability Instability Temperature Conditions of Instability Incompatibility with various substances Corrosivity The product is stable. Excess heat, incompatible materials, dust generation. Reactive with oxidizing agents, acids, alkalis. Non-corrosive in presence of glass.
Polyethylene glycol 335 Page Number: 4 Corrosivity Polymerization Will not occur. Section. Toxicological Information Routes of Entry Toxicity to Animals Chronic Effects on Humans Other Toxic Effects on Humans Toxicity to Animals Chronic Effects on Humans other Toxic Effects on Humans Absorbed through skin. Inhalation. Ingestion. Acute oral toxicity (LD5): > mg/kg [Rat]. Acute dermal toxicity (LD5): 2 mg/kg [Rabbit]. Slightly hazardous in case of skin contact (irritant, permeator), of ingestion, of inhalation. Acute Potential Health Effects: Skin: May cause mild skin irritation. May cause a more significant irritation if skin is abraded. It can be absorbed through the skin and cause systemic effects. Eyes: May cause mild, slight, temporary eye irritation. Corneal injury is unlikely. Inhalation: Inhalation of dust may cause respiratory tract irritation. A single exposure is unlikely to be hazardous. Ingestion: Very low toxicity. May cause nausea, vomiting. It may affect the kidneys, metabolism (metabolic acidosis, hypocalcemia), cardiovascular system (arrhythmias), liver. Chronic Potential Health Effects: Skin: Prolonged or repeated skin contact is not likely to cause significant irritation. There have been findings of metabolic acidosis, hypocalcemia, and hyperosmolality, kidney failure and death occuring in burn patients repeatedly exposed to PEG-containing topical medications. The use of topical medications containing Polyethylene Glycol may not be appropriate in severely burned patients or individuals with impaired renal function. Ingestion: Prolonged or repeated ingeston may cause anaphylaxis, an allergic reaction, and other symtoms similar to that of acute ingestion. Section 2. Ecological Information Ecotoxicity BOD5 and COD Products of Biodegradation Toxicity of the Products of Biodegradation the Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The product itself and its products of degradation are not toxic. Section 3. Disposal Considerations Waste Disposal Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Polyethylene glycol 335 Page Number: 5 Section 4. Transport Information DOT Classification Identification Not a DOT controlled material (United States). Special Provisions for Transport DOT Section 5. Other Regulatory Information and Pictograms Federal and State Regulations California Proposition 65 Warnings Other Regulations Minnesota: Polyethylene glycol 335 TSCA 8(b) inventory: Polyethylene glycol 335 California prop. 65: This product contains the following ingredients for which the State of California has found to cause cancer which would require a warning under the statute: No products were found. California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. EINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances. Canada: Listed on Canadian Domestic Substance List (DSL). China: Listed on National Inventory. Japan: Listed on National Inventory (ENCS). Korea: Listed on National Inventory (KECI). Philippines: Listed on National Inventory (PICCS). Australia: Listed on AICS. Other Classifications WHMIS (Canada) Not controlled under WHMIS (Canada). DSCL (EEC) This product is not classified according to the EU regulations. HMIS (U.S.A.) Health Hazard Fire Hazard Personal Protection E National Fire Protection Association (U.S.A.) Health Flammability Specific hazard WHMIS (Canada) DSCL (Europe) TDG (Canada) ADR (Europe)
Polyethylene glycol 335 Page Number: 6 Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses. Section 6. Other Information MSDS Code References Other Special Considerations P3988 Major Uses: Lubricant for rubber molds, textile fibers, and metal forming operations; in food and food packaging; in cosmetics; in water paints, paper, coatings, polishes; in the ceramic industry; pharmaceutic aid (ointment and suppositoy base; in plasticizers, softening agents, solvents, dispersing agents, binders; chemical intermediates Validated by Sonia Owen on /4/22. Verified by Sonia Owen. Printed /3/23. CALL (3) 56-8 Notice to Reader All chemicals may pose unknown hazards and should be used with caution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned in this MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based on the actual conditions of use. While this MSDS is based on technical data judged to be reliable, Spectrum Quality Products, Inc. assumes no responsibility for the completeness or accuracy of the information contained herein.