lipomoist 2036 A MOISTURISING & FIRMING MOLECULAR FILM

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A MOISTURISING & FIRMING MOLECULAR FILM v1

SIGNS OF AGING As we age, skin loses firmness and elasticity. Firmness reduced collagen synthesis increased collagen degradation increased MMP expression & collagen glycation. time

RECOVERING FIRMNESS! Boosting cellular protein levels, skin firmness can be recovered. Focus on: Collagen type IV The most abundant structural component of basement membranes. It constitutes a stable scaffold for the basal lamina of the Dermo- Epidermal Junction. It serves as anchoring support for cells and other constituens of the basement membrane.

MOLECULAR FILM MICROFLUIDISATION Xanthan Gum Pectin Continuous process where the product passes through high pressures Microfluidisation Molecular Film Improving delivery of actives Enhancing moisturisation Delivery system that helps the active ingredients to penetrate more efficiently. Occlusive film that minimises TEWL. STANDARD FILM MOLECULAR FILM Horny Clear Granular Prickle Basal Epidermis

Total Protein (µg) IN VITRO EFFICACY (I) 1. Increase of cellular protein formation on keratinocytes Human keratinocytes spread over a feeder layer of fibrobalsts of the culture cell 3T3 were used. Total protein content was determined with the crystal violet test. Measurements were taken after 5 and 10 days of incubation. 2000 1500 1000 500 5 days 10 days 0 Control 1 ng/ml 1 mg/ml increased significantly the total protein content

Integration Units IN VITRO EFFICACY (II) 2. Increase of Collagen type IV Reconstituted skin was incubated for 5 and 10 days with 1mg/ml of Lipomoist 2036. Collagen type IV increase was determined by the Dot Blot test. 200 150 100 50 +10% +20% 5 days 10 days 0 Control Control lipomoist 1 mg/ml 2036 1mg/ml increases Collagen type IV levels 10% increase after 5 days and 20%, after 10 days.

COSMETIC BENEFITS MOISTURISATION & FIRMNESS for the skin Molecular Film with a firming effect Enhanced delivery of the actives Increase of collagen levels lost due to aging

TECHNICAL INFORMATION DESCRIPTION Molecular film containing a submicrodispersion of heteropolysaccharides obtained by microfluidising techniques that confers a pleasant feeling to the skin, increasing skin moisture and firmness. APPEARANCE Opaque gel. INCI Water (Aqua), Xanthan Gum, Pectin, Hydrolyzed Vegetable Protein, Serine, Arginine, Proline, Disodium EDTA. Please contact us for information on the preservative system. PROPERTIES Lipomoist 2036 forms a moisturising protective film on the skin. It boosts cellular protein formation. APPLICATIONS Lipomoist 2036 can be used in O/W emulsions, body milks, gels, sera and in general in any skin care formulation where a moisturising and firming effect is required. DOSAGE 3-10%

A MOISTURISING & FIRMING MOLECULAR FILM Disclaimer: While the claims and supporting data provided in this publication are believed to be reliable and they are presented free and for guidance only, there are no warranties of any kind. All expressed and implied warranties are disclaimed. The recipient is solely responsible for ensuring that products marketed to consumers comply with all relevant laws and regulations. LIPOTEC is the exclusive holder of the both industrial and intellectual property rights identified herein. Recipient of this publication agrees to indemnify and hold harmless each entity of the LIPOTEC organization for any and all regulatory action arising from recipient s use of any claims or information in this publication, including, but not limited to, use in advertising and finished product label claims, and not present this publication as evidence of finished product claim substantiation to any regulatory authority. All tradenames, trademarks, copyrights and images used herein belong to their respective and lawful owners