LASIK SBK THE COMPARATIVE ANALYSIS OF DRY EYE SYNDROME OF LASIK AND SBK OF MONGOLIAN PATIENTS IN INNER MONGOLIA

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1 224 Journal Of Inner Mongolia Medical University June 2018 Vol.40 No.3 LASIK SBK * laser in situ ker - atomileusis LASIK Sub-Bownom-keratomileusis SBK ~ LASIK 60 SBK 60 1wk 1mo 3mo 6mo fluorescence staining FL tear break-up time BUT SchirmerⅠtest SⅠt 1wk 1mo LASIK SBK FL fluorescence staining FL LASIK 3mo 6mo BUT 1wk 1mo 3mo LASIK SBK 6mo P>0.05 SⅠt 1wk 1mo 3mo P<0.05 SBK 6mo P > 0.05 SBK LASIK SBK LASIK R A DOI: /j.cnki.issn x X THE COMPARATIVE ANALYSIS OF DRY EYE SYNDROME OF LASIK AND SBK OF MONGOLIAN PATIENTS IN INNER MONGOLIA XING Jian-nan ZHAO Hai-xia SUI Yao The Affiliated Hospital Inner Mongolia Medical University Hohhot China Abstract Objective To compare the changes of dry eye after laserinsitukeratomileusis LASIK and Sub-Bowman-Keratomileusis SBK for Mongolian patients in Inner Mongolia.Methods Retrospective analysis from September 2015 to September 2016 there were 120 Mongolian patients in three generations are all Mongolians come to our ophthalmology department to have myopia operation.there are 60 patients in group LASIK and 60 patients in group SBK. And observe the changes before operation and the changes that happened in fluorescence staining FL tear break-up time BUT and SchirmerⅠ test SIT after the operation for one week one month three months and six months.results After the operation for one week and one month we can see the dot dyeing of corneal epithelium of the FL of both group LASIK and group SBK and the number of corneal staining in group LASIK was more.the statisti nmghhzhx@ 163.com

2 cal results were of statistically significance and the proportion of the number of corneal staining eyes of two groups in the three months and six months after operation was not statistically significant.in the two groups the difference was statistically significant between the two groups in the one week one month and three months after the BUT operation.and LASIK group has a shorter breakup time of tear film and the SBK group enjoys a shorter recovery time.however there was no significant difference between the two groups in the six months after operation.the SIT experiment results of the patients in two groups shows that the comparative difference of the two groups in the one week and three months after operation was of statistically significant.and the SBK group has a shorter recovery time of tear secretion function while the data in the six months after operation was not statistically significant. Conclusion The Mongolian patients in Inner Mongolian are all tend to cause dry eye syndrome with different levels after the SBK operation and LASIK operation.and compare to those patients who accepted LASIK operation those patients who accepted SBK operation enjoys a shorter recovery time. Key words laserinsitukeratomileusis sub-bowman-keratomileusis dry eye LASIK SBK LASIK ~ ± 1.3 SBK Trokel ~ 34 26± % 3 4 LASIK LASIK SBK LASIK Moria M2 SBK ~ 110μm LASIK SBK 100mm 130 ~ 160μm 9.0 ~ 10.5mm 5 BSS 6 LASIK SBK 1d ~ LASIK SBK 2013

3 226 Journal Of Inner Mongolia Medical University June 2018 Vol.40 No min +Schirmer I 5mm /5min 2 +BUT 5s 3 +5mm /5min <SchirmerI 10mm /5min+ 4 +5S<BUT 10S cornealfluorescence staining FL 1wk 1mo LASIK SBK % LASIK P<0.05 6mo 3mo P> ~ ~ 30 1 >30 2 BUT 1wk 1mo 3mo 3 7 P<0.05 LASIK tear break-up time BUT 1.5 SPSS 16.0 x±s 珋 t P< BUT s SBK 3 6mo P> SⅠt Schirmer Ⅰ 1wk 1mo 3mo SchirmerⅠtest SⅠt P< SBK 6mo P > 1 / Tab.1 1 LASIK SBK x±s 珋 Comparison of corneal FL scores between LASIK group and SBK group 珋 x±s 1wk 1mo 3mo 6mo LASIK 0.37± ± ± ± ±0.551 SBK 0.38± ± ± ± ±0.475 t P Tab.2 2 LASIK SBK BUT s x±s 珋 Comparison of corneal BUT s between LASIK group and SBK group 珋 x±s 1wk 1mo 3mo 6mo LASIK 14.92± ± ± ± ±0.676 SBK 14.87± ± ± ± ±0.606 t P

4 Tab.3 3 LASIK SBK SⅠt mm x±s 珋 Comparison of corneal SⅠt mm between LASIK group and SBK group 珋 x±s 1wk 1mo 3mo 6mo LASIK 15.08± ± ± ± ±0.503 SBK 15.13± ± ± ± ± t P wk SBK LASIK SBK LASIK SBK LASIK 8~ J ~ 9 2 Solomon KD Fernandez de castro LE Sandoval HP et al. 9 ~3 satisfaction J.Ophthalmology Dawson DG Grossniklaus HE Mccarey BE et al. Biomechanical and wound healing characteristics of corneas after 12 LASIK excimer laser keratorefractive surgery is there a difference 12 between advanced surface ablation and sub-bowman's keratomil-eusis J.Refract Surg SBK 4 Ambrosio rjr Tervo T Wilson SE. LASIK - associated dry eye and neurotrophic epitheliopathy pathophysiology and SBK 3mo 5. LASIK 6mo J LASIK J J SBK J mm LASIK Beheshtnejad AH Hashemian H Kermanshahani AM et 130mm LASIK al. Evaluation of tear osmolarity changes after photorefractive keratectomy J. Cornea J SBK LASIK SBK LASIK world literature review quality of life and patient strategies for prevention and treatment J. Refract Surg 233

5 Gustillo Ⅲ 42Suppl1 SI-S12 vsd J vsd J Vsd J M M. 4. and negative pressure wound therapy vacuum assisted J Acad Orthop Surg J Fleischman W Becker U Bischoff M et al.l vacuum seal -ing indication Technique and results J.Eur J Orthop Surg T rauma Krug E Berg L Lee C et al. Evidence-based recommendations for the use of negative pressure wound therapy in traumatic wounds and reconstructive surgery steps towards an international consensus J. Injury J Wong SL Schneider AM Argenta LC et al. Loxoscelism closure an experimental study J.Int Wound J Streubel PN Stinner DJ Obremskey WT.Use of negativepressure wound therapy in orthopaedic trauma J. J Am 18. J vsd J 檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪檪 Muller LJ Vrensen GF Pels L.Architecture of human corneal nerves J.Invest Ophthalmol Vis Sci Lee JK Chuckrs Park CY. Femtosecond laser refractive surgery small - incision lenticule extraction vs femtosecond laser-assisted lasik J. Curr Opin Ophthalmol functional changes in corneal innervation after laser in situ keratomileusis and their relationship with dry eye J. J lasik J J Alghamdiya Mercadoc Mcclellanal et al.epidemiology of meibomian gland dysfunction in an elderly population J. Cornea Bhandariv Reddyjk Relekark et al.non-invasive assessment of tear film stability with a novel novel corneal topographer in indian subjects J.Int phthalmol Moreno-barriuso E Marcos S Navarro R et al.comparing laser ray tracing The spatially resolved refractometer And the hartmann - shack sensor to measure the ocular wave aberration J.Optom Vis Sci Chao C Stapleton F Zhou X et al. Structural and Graefes Arch Clin Exp Ophthalmol Chaurasia SS Luengo gimeno F Tan K et al.in vivo real- 15. time intraocular pressure variations during lasik flap creation J. Invest Ophthalmol Vis Sci J

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