2nd TEOXANE EXPERT DAY

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1 Contact TEOXANE Geneva 105 rue de Lyon Les Charmilles CH-1203 Geneva Tel: Fax: TEOXANE France 63 avenue Franklin D Roosevelt F Paris Tel: Fax: info@teoxanefrance.com TEOXANE Germany Am Lohmühlbach 17 D Freising Tel: Fax: info@teoxane.de Partners Schönheit besitzt Konzept Beauty needs concept FINAL PROGRAM 2nd TEOXANE EXPERT DAY November 19th, 2011 in Berlin

2 CHRONICLE - TEOXANE LABORATORIES Dear All EFFECTIVE SAFE LONG-LASTING TEOXANE Laboratories were created in 2003 in Geneva and are specialized in the conception and manufacture of hyaluronic acid-based injectable dermal fillers. On the strength of their success, thanks to the high standard quality products and their daily research for innovation, TEOXANE Laboratories are present in over 90 countries worldwide. They are known as an uncontested dermal filler market leader. In few years, TEOXANE Laboratories took over the third worldwide rank among hyaluronic acidbased dermal fillers manufactures. In 2011 more than 2 Mio. syringes have been injected worldwide* 2003: TEOXANE Laboratoires creation. Manufacturing facility built in central Geneva. 2004: Class III CE Mark approval is obtained for products. The first products are marketed: Meso, Global Action and Deep Lines. 2005: Creation of two subsidiaries: TEOXANE France and TEOXANE Germany. 2006: Production area is doubled in size. New products are launched: Kiss, Ultra Deep and First Lines. TEOXANE LABORATORIES are pleased to welcome you on the 2 nd TEOXANE EXPERT DAY in Berlin. After the great success of the 1 st TEOXANE EXPERT DAY last year in Munich, this event is turning into a milestone for all (TEOSYAL-) Experts. With it s main topic BEAUTY NEEDS CONCEPT, the 2 nd TED is aimed to present you more than just injection techniques of HA. Indeed, we are going a step further in aesthetic education thanks to a high quality medical training focusing on the most current trends and developments in anti-aging medicine as well as innovative interdisciplinary techniques. By looking beyond the horizon and with a thoughtful BEAUTY-CONCEPT, you will be able to reach continuously patients satisfaction with effective, safe and long lasting results. These three pillars have also been the guiding vision of TEOXANE LABORATORIES since They remain the foundation upon which we continue to build our success, and which have allowed us today to be a key leading international brand represented in over 90 countries. Safe, with complete control of the manufacturing process, more than 6-year clinical follow-up and more than 2 million syringes injected. Effective, thanks to our exclusive and patented technology, with an optimal cross-linking process, and the most complete dermal filler range designed for each indication. Long Lasting, proved with several clinical studies realized by experts and independent laboratories. This year s edition program gather international renowned specialists. Thanks to their expertise, we are confident that you will find our lectures and demonstrations enlightening and inspiring. Furthermore, we would like to invite you to our get-together immediately after the end of the training day to exchange experiences with colleagues and widen your network. We are looking forward to have an exciting and successful meeting with you in Berlin. 2009: Launch of Ultimate and Cosmceuticals. 2010: Launch of range containing Lidocaine. 2011: Launch of Redensity [ I ]. Yours sincerely Valérie Taupin CEO TEOXANE LABORATORIES GENEVA *Data March 2011

3 T H E B E S T O F H Y A L U R O N I C A C I D LIGHT FILLING A new treatment to redensify the dermis for a light reflecting skin I 2 nd TEOXANE EXPERT DAY Beauty needs concept 08:30 09:00 Registration 09:00 09:15 Welcome Dr. Wolfgang REDKA-SWOBODA (Donauwörth, GER) 09:15 11:15 Enhancing anatomical facial vectors for full face optimization Dr. Patrick TRÉVIDIC (Paris, FR) 11:15 11:30 Coffee break 11:30 12:30 Combination of fractional-co2-laser and HA-filler PD. Dr. Florian VELTEN (Frankfurt, GER) 12:30 13:30 Lunch break 13:30 15:00 Total facial sculpting with HA-fillers and BTX - a marriage made in heaven Dr. Bob KHANNA (Reading, UK) 15:00 15:30 Coffee break 15:30 17:00 Hand rejuvenation plus nips and tricks for more result with HA M. Sc. Agnes LETTERFORS (Stockholm - Gothenburg, SE) 17:00 18:00 Redensity [ I ] - a new concept between filling techniques and mesotherapy Dr. Britta KNOLL (Munich, GER) 18:00 18:45 Create a beautiful smile Innovative and complex treatment concepts Prof. Dr. Marcel WAINWRIGHT (Düsseldorf, GER) 18:45 19:00 Final discussion 19:00 21:00 Get-together Medical Director: Dr. Wolfgang REDKA-SWOBODA (Donauwörth, GER) Moderator: Dr. Stefan LIPP (Düsseldorf, GER) EXCLUSIVE & SYNERGETIC FORMULA 15mg/g Hyaluronic Acid Dermo-Restructuring Complex Lidocaine LOCATION: Hotel PALACE Budapester- Str. 45 D Berlin

4 Dr. Patrick TRÉVIDIC Enhancing anatomical facial vectors for full face optimization Dr. Patrick Trevidic is a plastic, reconstructive and aesthetic surgeon based in Paris, France and is the Head of the Surgery Department at the Hôpital Sainte-Anne. He majored in Head and Neck Oncology and Maxillo-Facial Prosthesis. A recognized surgeon of the French Medical Council, he is also specialized in maxillofacial surgery and is a member of various international reconstructive and aesthetic societies. He has been instrumental as a key investigator in several anti-aging studies, and has been at the forefront of many others. Dr. Trevidic has published more than 50 scientific articles in various periodicals and international journals and is often called upon to present his work at international congresses. To date, he has participated in over 100 medical congresses in France, Europe and the rest of the world. As well as serving as scientific director of Expert2Expert, the renowned noted European group of surgeons and cosmetic specialists, he is also scientific director for the Anti-Aging Medicine World Congress, and the European Master in Aesthetic and Anti-Aging Medicine. In 2010, Dr Trevidic and Dr Ingallina published Anatomy and botulinum toxin injections, a reference book based on expert observations. Dr. Trevidic is a professor and lecturer on surgery at several universities and schools of medicine in France and abroad.

5 PD. Dr. Florian VELTEN Combination of fractional-co2-laser and HA-filler Since 08/11 President of the German-French Society of esthtetic medicine and mesotherapy Since 01/09 Scientific director of the french association for esthetic medicine and mesotherapy (AMME - association du mésothérapie et médicine esthétique) Since 05/08 Founder and head physician of the dermatological practice Hautarztpraxis Velten Frankfurt Two employed medicines; 5 medical aids, treatment of more than patients up to now Lectures in dermatology at the University of Heidelberg, Dep. of Dermatology Mannheim Services: classical dermatology; esthetic dermatology (filler, botox, mesotherapy incl. mesohair, mesoscratch, bodysculpturing, laser, IPL) dermatological & esthetic surgery; professional dermatology, allergology, mesotherapy 11/07 French Board certification for dermatology and venereology (Strasbourg, France) 03/07 German Board certification for allergology (Freiburg, Germany) 07/07 Habilitation in dermatology (state-certified permanent qualification for professor posts) (Univ. of Heidelberg Germany) 03/07 German Board certification for dermatology and venereology (Freiburg, Germany) 05/01-04/08 Dermatological services, research assistant, Group leader dendritic cells University of Heidelberg, University Medical Ctr. Mannheim, Dep. of Dermatology, Mannheim, Germany (Head: Prof. Dr. S. Goerdt) Clinical service in general dermatology, allergology, oncology, and dermatological surgery 09/99-04/01 Postdoctoral Research Associate Lineberger Comprehensive Cancer Research Center., Laboratory of Mutagenesis and Molecular Therapeutics, University of North Carolina at Chapel Hill, USA (Head: Dr. J.M. Vos) Engineering of Epstein-Barr Virus-based mammalian artificial episomal chromosomes targeting human and non-human mammalian cells 03/98-08/99 Project manager Molecular Biology & Biotechnology Federal Research Center, Kiel, Germany (Head: Prof. Dr. J. Schrezenmeir) Development of alginate and hyaluronic acid-based extracellular matrices for xenotransplantation Biochemical and molecular-biological training of medical students at the Biochemical Institute of the University of Kiel (Head: Prof. Dr. R. Schauer) 03/96-02/98 Postdoctoral Research Fellow Lab. de Radiobiologie et d Etude du Génome INRA-CEA, Jouy-en-Josas, France (Head: Dr. M. Vaiman) 09/94-02/96 Internship in Dermatology, Immunology, and Allergology Wilhelms University Münster, Germany (Head: Prof. Dr. T. Luger) Clinical service in allergology, oncology, dermatological surgery, and general dermatology Membership: Deutsche Dermatologische Gesellschaft (DDG), Deutsche Gesellschaft für Dermatochirurgie (DGDC), European Academy of Dermatology and Venereology (EADV), Association du mésothérapie et médicine esthétique (AMME), Deutsche Gesellschaft für Mesotherapie (DGM)

6 Dr. Bob KHANNA Total facial sculpting with HA-fillers and BTX - a marriage made in heaven Dr. Khanna is a Cosmetic and Reconstructive Dental Surgeon. He runs clinics in Ascot and Reading and carries out a full spectrum of treatments from Aesthetic Dentistry, Surgical Implantology and bone regeneration procedures to full mouth rehabilitation. He was one of the first dentists in the World to venture into facial aesthetic procedures utilising Botulinum Toxin and Dermal Fillers in Shortly after, due to his great success with such treatments he helped develop the concept of hands on training courses in facial aesthetics for other medical and dental professional colleagues. Internationally renowned as a leading lecturer, trainer and expert in aesthetic medicine, Dr. Khanna has trained over 8000 Doctors, Dentists and Plastic Surgeons in non-surgical facial rejuvenation procedures and has developed many of the newer techniques used today. In 2003 Dr Bob Khanna was awarded with a Fellowship from the International Academy of Dental Facial Aesthetics in New York, an accolade shared by some of the worlds most eminent Dentists. He is Founder and President of the highly acclaimed International Academy of Advanced Facial Aesthetics (IAAFA) which is supported by many Internationally accomplished Dentists, Doctors, Plastic surgeons and Dermatologists. Dr Bob Khanna was awarded with the Best training course of the year at the Aesthetic medicine awards 2008 as voted by the profession and UK Private Dentist of the Year Dr Bob Khanna was appointed as Lead Clinical lecturer in facial aesthetics at the Royal College of Surgeons (London) in 2009 and is Clinical director and author of the facial aesthetics module of the Aesthetics Msc at Kings College London. Additionally he has authored over 30 publications in both dental and medical journals in the Uk and Internationally and is currently in the process of creating a full Msc in Facial aesthetics at the Kings college London. He is also an invited faculty board member of IMCAS(Europe,Asia and India).

7 M. Sc. Agnes LETTERFORS / Hand rejuvenation plus nips and tricks for more result with HA M. Sc. in Biomedicine / Neurophysiology. University lecturer in anatomy / physiology since 22 years.nurse, specialized in anesthesia, intensive care and dermatology since Lecturer and Courses for University Uppsala, Meedical School since Education and experience in cosmetic surgery since years experience in fillers and dermatology treatments. Long term experience in Balneology, Hydrotherapy and Spa-therapy from Hungary and other countries.author of two scientific articles on obesity, together with Professor Laszlo Halmy, Budapest, Hungary. International Masters Programmes/courses in Anti-Ageing & Aesthetic Medicine since 10 years.

8 Dr. Britta KNOLL Redensity [ I ] - a new concept between filling techniques and mesotherapy She graduated as a medical practitioner at the University of Erlangen, Germany, in Scholarship for 1 year in France at the Bretonian University of Rennes. Trained in 1983/84 by the originator of mesotherapy, Dr. Michel Pistor in Paris, she has performed over 20,000 mesotherapy procedures over the past 25 years. Since 1989 lecturer and teacher of mesotherapy on a national and international level, in congresses at Paris, Moscow, Vienna, Algier, Berlin, Madrid, Dubai and Mexico Foundation of the German Mesotherapy Society Up to now: presidency, organisation and administration of the Society and its activities, 920 members in Residency at a private 100 bed-clinic in Bavaria, specialisation on complementary oncology and holistic medicine. Approval in general medicine and naturopathy by the Bavarian Medical Association Starting her own clinic for general medicine and naturopathy in Munich, specialisation on mesotherapy in pain-management and non-surgical aesthetic procedures, oncology, holistic approach to anti-aging therapies. Customized patient care Assistance to the foundation of the Austrian Mesotherapy society. Since 2006 Vice president of the International Mesotherapy Society, Paris Consulting specialist in the leading Bahrain private plastic surgery hospital. Extensive experience with Arabic patient-care Assistance to the foundation of the Aserbaijan Mesotherapy society Author of the Illustrated Atlas of Mesotherapy in Aesthetic Medicine and Mesotherapy in Cosmetics Lecturer in the Master Study of Integrative Medicine at the Steinbeis University Berlin. Member and accredited lecturer of the Bavarian Medical Association Member of the French Mesotherapy Society Member of honour of the Swiss Mesotherapy Society

9 Prof. Dr. Marcel A. WAINWRIGHT Create a beautiful smile Innovative and complex treatment concepts Studies at University of Aachen (Ger) 1996 Promotion at University of Aachen with summa cum laude Assistant Dentist in Aachen and Bottrop (Ger) Associated Practice Uzelle/Wainwright 2006 Employed Implantologist in the largest private clinic in Netherlands Employed Dentist/ Associated Practice with Prof. Dr. Martin Jörgens, Dentalspecialists in Duesseldorf (Ger) 2007 Associated Practice Prof. Dr. Martin Jörgens/Prof.Dr. Marcel Wainwright, Foundation of the Educational Center for Implantology and Lasermedicine Kaiserswerth 2009 Foundation of Whitelounge Duesseldorf Activities: Languages: English, French, German, Dutch, Spanish Member of DGI, DGZI, ICOI, DGZMK, AAID, DGKZ, Certified Member of ESCD, Fellow IADFE (N.Y.) Professor for Ultrasonic Surgery and Implantology at State University of Seville (Spain). Postgraduate Mastercourse Conductor, Student s education programs and research coordination since Guest Lecturer of Heinrich-Heine-University Duesseldorf at the Institute for Anatomy and Neuroanatomy (Prof. Dr. Mai) and Course-Leader for Implant- and Ultrasonic Surgery on Cadavers Tutor for Implant courses at the University Santa Clara and Santi Spiritu, Cuba Co-Inventor of surgical techniqes and instruments for ultrasonic surgery with Acteon and the TKW-Research Group (Intralift, Bonesplit, Tunneltechnique) Co-Inventor of the Intralift for the minimal invasive sinus floor elevation Co-Founder and Vice-President of the IAUSI (International Academy for Ultasonic Surgery and Implantology) Speaker for the ESCD Master Study MSc in Esthetic Dentistry Guest Lecturer of the University of North Carolina and director of Intralift -Courses (May 2008) Guest Lecture of the University of Guangzhou and Dalian (China) Member of the Dental Team Olympic Games Beijing (2008) and London (2012) 2010 Gold Medal of the Ukrainian Society for Maxillofacial Surgery and Implantology Speaker for the DGZI Curriculum for Implantology Speaker for the Steinbeis University for the Master of Science in Esthetic Dentistry 2010 More than 40 publications nationally and internationally. Numerous TV reports (Pro7, Sat1, RTL, WDR) Specializations: Minimal invasive oral bone augmentation techniques and implantology Full Face rehabs with dentistry, BTX and Fillers High esthetic metalfree full mouth rehabs Navigated oral surgery and implantology Oral soft tissue microsurgery

10 RANGE - INDICATIONS AND SUMMARY TABLE RANGE PRODUKTÜBERSICHT - INDICATIONS AND und SUMMARY INDIKATIONEN TABLE PARAMETER Meso First Lines First Lines Global Action Global Action Touch Up PARAMETER Deep Lines Deep Lines Kiss Kiss Ultra Deep Ultra Deep Ultimate Ultimate HA Concentration 15 mg/g 20 mg/g 25 mg/g 25 mg/g HA Concentration 25 mg/g 25 mg/g 25 mg/g 22 mg/g Lidocaine Concentration 0,3 % 0,3 % Lidocaine Concentration 0,3 % 0,3 % 0,3 % 0,3 % Volume-creating Capability Volume-creating Capability Needle 30G 1/2 30G 1/2 30G 1/2 30G 1/2 Needle 27G 1/2 27G 1/2 25G1 23G1 Treated areas Rehydration of the dermis with treatment protocol. Lines and superficial crows' feet and peribuccal wrinkles. All moderately pronounced wrinkles. Glabella wrinkles, moderately pronounced nasogenian folds and peribuccal wrinkles. All moderately pronounced wrinkles, ideal for touch-ups. Treated areas Highly pronounced wrinkles. Nasogenian folds and deep Marionette lines. Moderately pronounced tear troughs depression. Lip contour and volume. Very deep wrinkles in thick skin. Creates and restores volumes, facial contours. Cheeks, upper cheeks, chin, facial contours. Injection area Superficial dermis Superficial dermis Mid dermis Mid dermis Injection area Deep dermis Deep dermis Subcutaneous tissue Subdermal or pre-periosteal Blister pack 2 x 1 ml 2 x 0.7 ml 2 x 1 ml 2 x 0.5 ml Blister pack 2 x 1 ml 2 x 1 ml 2 x 1 ml 1 x 3 ml Estimated duration before top-up* 2-3 months 6 months up to 9 months up to 9 months Estimated duration before top-up* 9 months up to 9 months 12 months up to 18 months * Average duration depends on several factors: patient's skin type, severity of the wrinkle, type of injection (superficial, medium or deep dermis) and the injected volume. * Average duration depends on several factors: patient's skin type, severity of the wrinkle, type of injection (superficial, medium or deep dermis) and the injected volume.

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