Own Your Beauty. with the Belotero range. Enjoy natural results with a filler tailored to your needs.

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1 Own Your Beauty with the Belotero range Enjoy natural results with a filler tailored to your needs.

2 Show your emotions with conf idencefi When was the last time you dared to show your emotions with self-assurance and confidence? Belotero is here to make you feel good in your skin. No matter of your age or individual needs. Belotero offers a broad range of hyaluronic acid fillers tailored to your requirements. They give natural looking results without you losing facial expression or emotion. Bring back what you miss about feeling beautiful, happy and radiant. Because you have the choice to own your age and to own your beauty.

3 Don t let age limit you What is hyaluronic acid? As we age, the production of natural skin moisturisers (such as hyaluronic acid) slowly diminishes, first leaving fine lines and later wrinkles where our skin was once youthful, smooth and radiant. As the levels of collagen and elastin decline, over time our skin loses more and more elasticity. This results in decreased skin quality, a reduction of facial volume and a less youthful appearance overall. At the same time, our bone structure alters as we get older, which gradually changes our facial features. Hyaluronic acid (HA) is our skin s natural moisturiser; you might have come across it in your day and night creams. Naturally present, it binds water which moisturises the skin and provides tightness. Over time, its natural production decreases and the skin becomes flaccid. When only applied externally as a cream or serum, however, HA cannot pass through all layers of our skin. For a truly skin-changing result, HA must be injected into the different layers of the skin to achieve instant, lasting and truly visible effects. What is the Belotero range? Belotero is a premium hyaluronic acid filler range and the right choice for anyone seeking natural-looking results with a long-lasting effect. The Belotero filler range achieves excellent skin integration and provides subtle, smooth results while respecting the natural contours of your face. Belotero offers a broad range of different hyaluronic acid fillers tailored to your needs. The filler is administered into the different layers of the skin with a very fine needle. The face has distinct areas where our skin varies in thickness and has different requirements depending on which zone is treated. Therefore your doctor might choose a different product for the perioral lines than for the treatment of deep nasolabial folds.

4 Surprise yourself and others Smoothing deep folds When it comes to deep folds, the nasiolabal folds are usually those that bother most women as these folds become more pronounced over time. The Belotero range can be used for a subtle, smooth correction of these deep folds. Looking fresh and rested again Beautiful eyes are an essential feature of our beauty. A treatment with the Belotero range can help to reduce the signs of aging in the delicate eye area*. There are far more treatment options you can address with the fillers of Belotero than you might expect. Apart from filling wrinkles, the fillers can hydrate your skin or restore facial volume where required. Refreshing face proportions and treating wrinkles It is not just a single fold that gives the face an aged expression. A combined treatment with the Belotero range can reduce wrinkles, refresh contours and redefine lips for an overall younger look.

5 If you are looking for a filler with excellent skin integration for natural-looking results and a reduction of the signs of aging, the Belotero family is your perfect choice. Which filler meets your individual needs? Skin hydration for: face neck décolletage back of hands Correction of fine lines, such as: peri-oral lines Correction of moderate lines, such as: moderate nasolabial fold glabellar lines* moderate peri-oral wrinkles lip contouring Correction of deeper lines, such as: deep nasolabial fold lip volume marionette folds Restoration of facial volume in: cheeks and cheekbones chin facial volume loss * Belotero Balance can be injected in the glabellar area only by trained experienced practitioners with a deep knowledge of the anatomy. Injection of dermal fillers into this area could potentially lead to local vascular occlusion, ischemia and necrosis.

6 NATURAL1 RESULTS The extended portfolio of advanced hyaluronic acid fillers in the Belotero range are designed to complement each other. Therefore, you can tailor your personal beauty package to your skin s different needs. You are unique and deserve a unique treatment protocol. For the best possible outcome, discuss with your doctor which products are most suitable for you. VERY LOW PAIN LEVEL RESPECTS 3 FACIAL EXPRESSIONS HIGH PATIENT SATISFACTION 1 Prager W., Kerscher M. Investigator and Subject Satisfaction: Results from a Randomized, Evaluator-blinded, Split-face Study. Podium presentation at 5CC Conference, Cannes, France (September 3, September 6, 2015). 2 Fischer, T. C., G. Sattler and G. G. Gauglitz (2016). Hyaluron Filler Containing Lidocaine on a CPM Basis for Lip Augmen tation: Reports from Practical Experience. Facial Plast Surg 32(3): Buntrock, H., et al. (2013). Efficacy, safety, and patient satisfaction of a monophasic cohesive polydensified matrix versus a biphasic nonanimal stabilized hyaluronic acid filler after single injection in nasolabial folds. Dermatol Surg 39(7):

7 Frequently Asked Questions How is hyaluronic acid applied and how does it work? Hyaluronic acid (HA) is injected into the skin with a very fine needle. Naturally present in your skin, it binds water which moisturises the skin and provides tightness. Over time, its natural production decreases and the skin becomes flaccid. HA can be injected to replenish and smooth facial lines, wrinkles, acne scars or other skin flaws. You will see the effect immediately. Are there any side effects? There may be a reaction to punctures such as discoloration, a light pain sensation or mild to moderate redness and swelling, and pinpoint bleeding or bruising. However, these most common side effects are only temporary and usually disappear within a few days. Your doctor will advise you on side effects in more detail during your personal consultation. Are there any reasons I should not be treated with Belotero? Hyaluronic acid injectables, such as Belotero, should not be used if you suffer from autoimmune diseases, have allergies to the anaesthetic lidocaine, are hypersensitive to HA or during immunotherapies; if you have an inclination to proliferative scarring, skin inflammation or infection from punctures; during breastfeeding or pregnancy; when taking drug hemodilution; after pre-treatment with non-biodegradable fillers. Will my expression change? Don t worry; you will look fresher, more relaxed or rested, but you will not lose your ability to show your emotions and be yourself. How much time does the treatment take? At your first consultation, your doctor will discuss your individual treatment goals and expectations. Depending on the affected areas, one treatment will last between 15 and 45 minutes only. Does it hurt? Our fillers are available with lidocaine to reduce any sensation of pain you might feel. As Belotero can be applied with very fine needles, this helps to maximise your comfort. Will I be able to go back to work immediately? The results of a treatment are immediate and you will not need any subsequent rest period. Usually you can resume your daily activities right away. Which wrinkles can be treated with a hyaluronic acid filler? Not only can dynamic or static wrinkles be treated with a filler, but facial volume loss can also be restored and skin rehydrated. How long does the effect of hyaluronic acid last? This depends on various factors such as a person s age, skin type, life habits and muscle activity. What can I do myself to obtain the best possible result after the injection? You can follow your normal daily routine, but should avoid applying make-up during the first 12 hours after treatment. For two weeks after your treatment, you should avoid saunas, Turkish baths and prolonged exposure to the sun or UV rays. Also, try to avoid putting any pressure on treated areas. * Treatment in the region of the eye must be performed by a trained and experienced practitioner with thorough knowledge of the anatomy. The model is an actual Belotero patient. Belotero is a registered trademark of Merz Pharma GmbH & Co. KGaA Belotero is manufactured by Anteis S.A 18, Chemin des Aulx, 1228 Plan-les-Ouates, Geneva Switzerland Merz Pharmaceuticals GmbH Eckenheimer Landstrasse Frankfurt am Main, Germany Date of preparation March 2017 Art.-Nr.: 5009

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