AC MVS Lips Lip Plumping. Tomorrow s Vision Today!

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Lip Plumping Tomorrow s Vision Today!

Technical Information: Product Code: 60050 INCI Name: Glycine Soja (Soybean) Seed Extract & Glycyrrhiza Glabra (Licorice) Leaf Extract & Phospholipids INCI Status: Approved Suggested Use Levels: 0.50 5.00% Suggested Applications: Lip Plumping

Lips as a Fashion Accessory Market Trends Popular for both aging populations & younger demographics Cosmetic surgery-type results from a topical cosmetic avoiding a large expense & painful recovery Hydrated, plumped & luscious lips

Plump Lips Achieving the Look! We must look at the injectable preparations available within the medical profession To augment the naturally occurring lip tissue, the most commonly used products are: Purified Collagen Reconstitued Human Tissue Matrix (HTM) The question then becomes, how can we topically deliver collagen to the lips so as to avoid medical procedures?

Overcoming the Obstacle Most lip preparations are lipid-based: Eliminates the possibility of using traditional delivery systems, i.e. liposomes Absence of hair follicles on the lips Solid particulate delivery systems are inefficient & ineffective Active Concepts developed AC MVS Lips, a self-assembling, microscale delivery system

Soybean Seed Extract Phospholipids are dispersed in a biomimetic fractionated soybean extract Enables the product to be easily incorporated into a lipophilic environment of a traditional lip product Upon application, the phospholipids naturally seed & migrate to the more hydrophilic interior of the lips In the hydrophilic environment, the phospholipids readily assemble into a multi-vesicular system Lips Swell Enhances the appearance of increased volume of the lips

Licorice Leaf Extract Licorice leaf extract has been shown to increase the rate of wound healing Directly involves the generation of new collagen fibrils Naturally complementing the function of the self-assembling vesicles, Active Concepts incorporated Licorice Leaf Extract into the AC MVS Lips formulation to: Induce the generation of new collagen Supplement the existing collagen present in the lips

In-vivo Sensory Study AC MVS Lips Subject Time Elapsed for Perceivable Effect 1 Perceivable effect within 5 minutes of application 2 Perceivable effect within 2 minutes of application 3 No perceivable effect within 5 minutes of application 4 Immediate perceivable effect upon application 5 Perceivable effect within 3 minutes of application Results: The data suggests that using AC MVS Lips results in perceivable lip plumping effects within 5 minutes of application Protocol A panel of 5 women, ages 19-37, was assembled for testing Conducted to evaluate the ability of AC MVS Lips to effectively plump the lips & create perceivable fullness The women applied AC MVS Lips directly to their lips Each woman was asked to assess the amount of elapsed time prior to perceiving sensory plumping effects Each panelist abstained from using any lip care product for 3 days prior to the start of the study

Moisturization (µsiemens) In-vivo Moisturization Study AC MVS Lips 500 450 400 350 300 250 200 150 100 50 0 T=0 T=1 T=2 T=4 Time (Weeks) Protocol Equipment: DermaLab Skin Combo 10 M/F subjects 2 mg of each test material on their volar forearms Concentration: 2.0% AC MVS Lips is able to offer long term perceivable moisturization over time compared to control lotions in laboratory testing AC MVS Lips Control Lotion Results: Offering as much as 35% more moisturization than controls

Elasticity (VE) In-vivo Elasticity Study AC MVS Lips 1.6 1.4 1.2 1 0.8 0.6 0.4 Protocol Elasticity is an excellent measure for a number of common aging symptoms 10 M/F subjects Equipment: DermaLab Skin Combo Test area: inner forearm Concentration: 3.0% 0.2 0 T=0 T=1 T=2 T=4 Time (Weeks) AC MVS Lips Control Lotion Results: Able to increase skin elasticity (VE) by nearly 45% over the course of four weeks

Formulation Guidelines: Suggested Use Level: 2.0 15.0% ph Range Stability: 4 7 Solubility in Water: Water Dispersible Temperature Stability: <50 C Formulation Guideline: Incorporate during the cooling phase

Technical Information: Product Code: 60050 INCI Name: Glycine Soja (Soybean) Seed Extract & Glycyrrhiza Glabra (Licorice) Leaf Extract & Phospholipids INCI Status: Approved Suggested Use Levels: 0.50 5.00% Suggested Applications: Lip Plumping

ACTIVE CONCEPTS LLC THANK YOU For more information Visit our website! www.activeconceptsllc.com