WATER COAT NANOFIBERGEL (NFG )

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WATER COAT NANOFIBERGEL (NFG ) NISSAN CHEMICAL CORPORATION

WATER COAT of NFG is effective in a variety of items. Essence Moisturizing Active ingredient penetration enhancer Cream Reduce the stickiness of oil NFG WATER COAT Foundation Reduce shine Give a matte Shampoo Treatment Followed by a moist feeling by gently coat the scalp and hair 2

WATER COAT: Premixes of NANOFIBERGEL WATER COAT NANOFIBERGEL : In advance we have developed premixes containing a combination of NFG, polyvalent alcohol, and etc as a product. ES-01 BA-03 OA-03 TW-01W Palmitoyl Dipeptide-18 10.0% Palmitoyl Dipeptide-18 3.0% Palmitoyl Dipeptide-18 20.0% Plamitoyl Dipeptide-18 4.00% 1,2-Hexanediol 1.0% 1,3-Butanediol 0.2% 2-Ethyl-1,3-hexandiol 1.0% 1,3-Butanediol 1.00% Stearic acid 4.0% Cetanol 0.2% Propylene glycole 8.0% Stearic acid 0.48% Polyoxyetylen Laulyl ether 8.0% Water 77.0% Myristyl alcohol 1.8% Lauryl hydroxy sulfobetaine 20.0% Stearic acid 16.0% Polyoxyetylen Laulyl ether 20.0% Sodium hydroxide 40.00% Water 54.52% Water 74.8% Water 35.0% ES-01 BA-03 OA-03 TW-01W ph of premix 5 5 5 9 Cosmetics Quasi-drugs? In development In development In development Pharmacuticals In development In development 3

ヒト皮膚に浸みこむ Amount of hyaluronan has penetrated into human skin ヒアルロン酸量 [µg/cm 2 ] WATER COAT: Active ingredient penetration enhancer effect Essence Moisturizing Active ingredient penetration enhancer WATER COAT infiltrates such as hyaluronic acid to the skin 16 14 12 Penetration force five times up!! 10 8 6 4 2 0 Hyaluronic acid aqueous solution Without NFG Hyaluronic acid aqueous solution with NFG 4

Amount of water in the stratum corneum WATER COAT: Moisturizing Effect Essence Moisturizing Active ingredient penetration enhancer WATER COAT coats skin. And after skin lotion use, It maintains the moisture content of the skin. Moisturizing is also maintained after the lapse of time!! High moisturizing effect! General lotion without NFG Genaral lotion with NFG After 15min. After 30min. After 60min. After 120min. Test method: 1 Place the test sample to the forearm. 2 After one hour, wash with water without rubbing. 2 After washing with water, after 15min, after 30min, after 60min, and after 120min measure the amount of water in the stratum corneum 5

WATER COAT: It reduces the stickiness of the skin! Cream Reduce the stickiness of oil WATER COAT coats skin. It reduces the stickiness by oil oil water water oil With NFG 20% Jojoba oil + 80% water Green:water Red:Jojoba oil With NFG 60% Jojoba oil+40% water Even increase the amount of oil, It remains water is the continuous phase.

The reflected light intensity (a.u.)@45 WATER COAT: It reduces the shine of the skin Foundation Reduce shine Give a matte WATER COAT coats skin. It reduces sticky of oil and the shine of the skin! 1 With NFG 2 Without NFG 70 Shine 50% cut! Matte finish! 60 50 No shine Shine there Photograph after 15 minutes 40 30 20 oil water oil 10 skin 0 1 With NFG 2 Without NFG Measurement data after 15 minutes 7

WATER COAT: SEM observation of the reflected light sample Foundation Reduce shine Give a matte O/W solution with NFG O/W solution without NFG Oil phase is less in the surface layer oil Often the oil phase in the surface layer. oil Oil phase By oil droplets are embedded in NFG coating, the surface of the oil phase decreases Shine to prevention 8

WATER COAT: Come together hair better WATER COAT gently coats the scalp and hair. Hair of unity will be better after shampooing. Verification results under the same conditions: Photos after drying in both dryer α β Shampoo A α β Sodium cocoyl glutamic acid 7.30% 7.30% Potassium Cocoyl glutamic acid 2.40% 2.40% Sodium Cocoyl taurine 4.20% 4.20% Cocamidopropylbetain 12.00% 12.00% Coconut oil fatty acid diethanolamide 4.00% 4.00% 1,3-BG 4.00% 4.0ko-0% Citric acid 0.35% 0.35% water 45.25% 45.75% B water 20.00% 20.00% ES-01 0.50% 0.00% C Polyoctanium-7 0.50% 0.50% toatal 100.00% 100.00% Hair washing by shampoo with NFG Hair washing by shampoo Without NFG 9

Effect that can be expected by the NFG addition: NFG サ Realize the NFG sample user Effects on skin care a)essence 1 Skin conditions(moist, smooth) will be better and the better the cosmetic glue b)uv milk 1 From the stimulation of UV absorbers and scattering agent, protect the skin, not red c)cleansig 1 After washing also, can the film, there is a sense of moisturizing Effect on the make-up a)bb cream 1 By suppressing the floating of sebum, inhibits the shine 2 It will not collapse makeup 3 People of dry skin is no longer dry Effect of the shampoo a)effect on the bubble: 1 good foaming 2 fine texture of foam b)effect on the hair 1 Hair is moist 2 Out the tension and stiffness in hair 3 To gently coat the hair and scalp 4 Out luster to hair 5 Hair of unity will be better 6 It has the better of the color ring 10

WATER COAT of NFG is effective in a variety of items. Essence Moisturizing Active ingredient penetration enhancer Cream Reduce the stickiness of oil NFG WATER COAT Foundation Reduce shine Give a matte Shampoo Treatment Followed by a moist feeling by gently coat the scalp and hair 11

An inquiry Nissan Chemical Corpration Advanced Materials Planning Division Nobuhide Miyachi E-mail: miyachin@nissanchem.co.jp 12